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53461
Mechanisms of organotropism in breast cancer and predicting metastasis to distant organs using deep learning
Published 2025-06-01“…Methods To investigate the mechanisms of organ-specific metastasis in breast cancer, we employed an integrative approach combining single-cell RNA sequencing, bulk RNA sequencing, ChIP-seq data, and deep learning techniques. Single-cell analysis provided detailed insights into cellular heterogeneity and microenvironment interactions at metastatic sites. …”
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53462
SLEEP DISORDERS AND THE RISK OF MYOCARDIAL INFARCTION AND STROKE IN MEN OF NOVOSIBIRSK CITY
Published 2014-09-01“…The program of screeing examination included the registration of social and demographic data, sleep disorders assessment with Jenkins C. …”
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53463
Multi-omics driven biomarker discovery and pathological insights into Pseudomonas aeruginosa pneumonia
Published 2025-05-01“…Data were analyzed using advanced statistical techniques to identify differentially expressed proteins and metabolites. …”
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53464
Exploring Ethical, Cultural, and Transnational Competence Among International Healthcare Management Students: An Australian Perspective
Published 2025-03-01“…A cross-sectional survey of 35 international postgraduate health services management students collected quantitative and qualitative data. Quantitative data were summarized using descriptive statistics, while thematic analysis, informed by the Gioia methodology, was applied to qualitative responses.Results: Key ethical challenges identified included healthcare inequity, resource allocation, and patient safety. …”
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53465
Understanding discrepancies in soil moisture from SMAP and AMSR2: insights into performance and dry-down behavior
Published 2025-12-01“…The satellite-derived SM data are evaluated and compared using 40 globally distributed SM observation networks at both regional (dense network) and grid scales. …”
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53466
Role of the Perceived Social Responsibility of the Company and the Psychological Mechanisms to Achieve the Employees' Creative Behavior (Case Study: Electro Kavir Company of Yazd)
Published 2025-03-01“…The data collection tool in this research was standard questionnaires, the validity of which was confirmed using the opinions of a number of experts in this field, and Cronbach's alpha coefficient and composite reliability were used to determine the reliability of the measurement tool, and the analysis method used in this research was structural equation modeling technique. …”
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53467
An immune-focused supplemental alignment pipeline captures information missed from dominant single-cell RNA-seq analyses, including allele-specific MHC-I regulation
Published 2025-08-01“…Nimble uses a previously developed pseudoaligner to process either bulk- or single-cell RNA-seq data using custom gene spaces. …”
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53468
Potential common mechanisms between primary Sjögren’s syndrome and Hashimoto’s thyroiditis: a public databases-based study
Published 2025-04-01“…Based on KEGG, PID, Reactome, and BioCarta enrichment analysis, pathway annotations were performed. A PPI network was developed using STRING. …”
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53469
The nonlinear relationship between the ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol and the risk of diabetic kidney disease in patients...
Published 2025-02-01“…The multivariable logistic regression analysis showed that T2DM patients with higher NHHR levels exhibited a 45% reduction in the risk of developing DKD in comparison to those with lower NHHR levels (Q2 vs. …”
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53470
School-level prediction and management of myopia in children and adolescents
Published 2025-08-01“…After two-year follow-up, 915,991 individuals were included in analysis. Data were analyzed from June 2022 to July 2023. …”
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53471
Risk factors and prognosis of silent cerebral infarction after transcatheter aortic valve replacement
Published 2025-04-01“…This was a single-center study including 613 patients with severe aortic stenosis undergoing TAVR, with all data collected prospectively in a dedicated database.We compared clinical baseline data, preoperative imaging results, perioperative factors, and intraoperative variables between patients with and without SCI according to VARC-3. …”
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53472
Obesity phenotypes and the risk of myocardial infarction: a prospective cohort study
Published 2019-07-01“…The analysis was carried out in individuals with a metabolically phenotype of healthy obesity (MHO). …”
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53473
A nomogram for predicting early bacterial infection after liver transplantation: a retrospective study
Published 2025-04-01“…Therefore, this study investigated the risk factors of early bacterial infections after liver transplantation and used them to establish a nomogram.MethodsWe retrospectively collected the clinical data of 232 patients who underwent liver transplantation. …”
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53474
Construction and validation of a meropenem-induced liver injury risk prediction model: a multicenter case-control study
Published 2025-05-01“…Univariate analysis and multiple logistic regression analysis were employed to identify the related factors for MiLI, and a nomogram risk prediction model for MiLI was constructed. …”
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53475
Qualitative Exploration of Speech Pathologists' Experiences and Priorities for Aphasia Service Design: Initial Stage of an Experience‐Based Co‐Design Project to Improve Aphasia Ser...
Published 2024-06-01“…Research questions and study design (e.g., analysis methods and assessment measures) were developed by the research team (authors L.A., V.J.P., D.A.C. and S.J.W.).…”
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53476
MTNR1B variants increase gestational diabetes mellitus risk in young Chinese pregnant women
Published 2025-06-01“…SNP-age interactions were further explored through stratified analysis and GRS. A predictive model was developed using logistic regression, validated with bootstrap resampling, and its clinical utility was evaluated with decision curve analysis. …”
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53477
Assessment of the carcinogenic potential of particulate matter generated from 3D printing devices in Balb/c 3T3-1-1 cells
Published 2024-10-01“…However, limited toxicological research data on 3D printing make it challenging to confirm a causal relationship between 3D printing and cancer. …”
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53478
Applicability evaluation of the GFR equations in Chinese patients with diabetes mellitus complicated with CKD
Published 2019-01-01“…Bland-Altman analysis was used to compare the consistency limits of eGFR and rGFR for each equation. …”
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53479
CHARACTERISTIC FEATURES OF PARATEXTS IN UKRAINIAN TRANSLATIONS OF THE HOLY SCRIPTURES
Published 2024-06-01“…The article’s assumptions are grounded in the interdisciplinary approach at the interface of translation studies, biblical studies, religious studies, and historiography. The objective of developing a classification of paratexts in Bible translations within historical, theoretical, and critical contexts is accomplished via the methods of analysis, synthesis, induction, and modelling. …”
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53480
Life cycle greenhouse gas emissions of conventional and alternative steel production methods in countries dependent on energy import: A South Korean case study
Published 2025-01-01“…The data used in the analysis was selected through a literature review and thermodynamic modeling of the process. …”
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