Investigating the preliminary adaptation of plants to different levels of salinity (Case study: Dust hotspot No 4, Khuzestan) by Maasoumeh Movaghari, bijan khalili moghadam, Leila Khalasi Ahvazi, Ashkan Yousefi, Amin Zorati Pour, Masoumeh Forouzani, seyed ata Siadat, zeinab Hazbavi, Mohammad Hossein Salehe Shooshtari

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Exploration of circulating metabolites in infants with abusive head trauma by Estelle Maret, Tatjana Sajic, Kim Wiskott, Sylvain Le Gludic, Federica Gilardi, Youssef Daali, Tony Fracasso, Aurélien Thomas

“…However, as recently demonstrated via analysis of serum proteomes of infant victims of AHT, large-scale omic analysis of blood serum samples could help identify molecules with high potential for early detection of human pathologies. …”
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Carer perspectives on overweight, obesity and dental caries in early childhood: findings from a systematic qualitative review by Heilok Cheng, Heilok Cheng, Heilok Cheng, Rebecca Chen, Rebecca Chen, Rebecca Chen, Bradley Christian, Bradley Christian, Jessica Appleton, Jessica Appleton, Jessica Appleton, Amit Arora, Amit Arora, Amit Arora, Amit Arora, Amit Arora, Elizabeth Denney-Wilson, Elizabeth Denney-Wilson, Elizabeth Denney-Wilson

“…There was high or potential risk of bias in qualitative methodology when studies did not address researcher-participant relationships or rigorous data analysis processes.DiscussionFindings highlight the need for strength-based messages for children's teeth and weight, increased understanding of formula and bottle feeding as obesity and ECC risk factors, and holistic approaches to care by dental and primary care professionals.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD42022348783, PROSPERO CRD42022348783.…”
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Study protocol for the Bio-HEAT study: Investigating the Biological pathways from HEAT exposure to preterm birth and other adverse maternal and child health outcomes in South Afric... by Lebohang Radebe, Nicholas B. Brink, Clive Gray, Marié Landsberg, Robyn Hetem, G Justus Hofmeyr, Phelelani T. Mpangase, Sibusisiwe Makhanya, Michael Urban, Shane Norris, Amy Wise, Valerie Vannevel, Karl-Gunter Technau, Matthew F. Chersich, Renate Strehlau, Ijeoma Solarin, Kimberly Mc Alpine, Darshnika Pemi Lakhoo, Admire Chikandiwa, Howard Chang, Margaret M. Brennan

“…Placental and cord blood analyses will assess foetal stress. Infant data will include medical history, hospital visits, neurodevelopment, anthropometric measurements, vital signs, and urine analysis. …”
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Protocol for a hybrid effectiveness-implementation clinical trial evaluating video-assisted electronic consent vs standard consent for patients initiating and continuing haemodialy... by Helen Healy, Ann Bonner, Rebecca B Saunderson, Martin Wolley, Chenlei Kelly Li, Pedro Henrique Franca Gois, Marina Wainstein, Matthew J Damasiewicz, Vera Y Miao, Kirsten Hepburn, Clyson Mutatiri, Bobby Chacko

“…Implementation of eConsent for HD will be evaluated concurrently using the Consolidation Framework for Implementation Research (CFIR) methodology. Analysis: For the randomised controlled trial, data will be analysed using intention-to-treat statistical methods. …”
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Prognostic factors for outcomes of idiopathic sudden sensorineural hearing loss: protocol for the SeaSHeL national prospective cohort study by Helen Blackshaw, Anne GM Schilder, Rishi Mandavia, Gerjon Hannink, Muhammad Nayeem Ahmed, Yaami Premakumar, Timothy Shun Man Chu, Tanjinah Ferdous, Nishchay Mehta, Joseph Manjaly, Maha Khan

“…The study objectives are to: (1) map the patient pathway and identify the characteristics of adult patients presenting to NHS ENT and hearing services with SSNHL, (2) develop a prognostic model to predict recovery for patients with idiopathic SSNHL and (3) establish the impact of idiopathic SSNHL on patients’ quality of life (QoL).Methods and analysis Study design: national multicentre prospective cohort study across 97 NHS trusts.Inclusion criteria: adult patients presenting to NHS ENT and hearing services with SSNHL.Outcomes: change in auditory function; change in QoL score.Analysis: multivariable prognostic model, using prespecified candidate predictors. …”
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Multimodal Deep Learning Integrating Tumor Radiomics and Mediastinal Adiposity Improves Survival Prediction in Non‐Small Cell Lung Cancer: A Prognostic Modeling Study by Ye Niu, Han‐bing Xie, Hao‐bo Jia, Lin Zhao, Le Liu, Ping‐ping Liu, Xue‐meng Li, Rui‐tao Wang, Yuan‐zhou Li

“…Model performance was evaluated using Harrell's concordance index (C‐index) and receiver operating characteristic (ROC) analysis. Risk stratification was performed using an optimal threshold derived from training data, with subsequent Kaplan–Meier survival curve comparison between high‐ and low‐risk cohorts. …”
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Interpractice variability in antibiotic prescribing for acute respiratory tract infections: a cross-sectional study of Australian early-career general practitioners by Elizabeth Holliday, Parker Magin, Amanda Tapley, Andrew Davey, Neil Spike, Mieke L van Driel, Alison Fielding, Josh Davis, Lisa Clarke, Ben Mitchell, Anna Ralston, Alexandria Turner, Katie Mulquiney, Jason Dizon, Emma Baillie

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Next-generation diagnostics of bloodstream infections enabled by rapid whole-genome sequencing of bacterial cells purified from blood culturesResearch in context by Vincenzo Di Pilato, Chiara Bonaiuto, Fabio Morecchiato, Alberto Antonelli, Tommaso Giani, Gian Maria Rossolini

“…Novel molecular approaches have been developed to provide faster results but are also affected by limitations. …”
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CNA landscape of HER2-negative breast cancer during administration of taxane-containing schemes of neoadjuvant chemotherapy by M. K. Ibragimova, E. A. Kravtsova, M. M. Tsyganov, N. V. Litviakov

“…The results were processed using Chromosome Analysis Suite 4.0 (Affymetrix, uSA) software. Statistical data processing was performed in Statistica 8.0 (StatSoft Inc., uSA) software.Results. …”
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Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness by Karamoko Niaré, Karamoko Niaré, Rebecca Crudale, Abebe A. Fola, Abebe A. Fola, Neeva Wernsman Young, Victor Asua, Victor Asua, Melissa D. Conrad, Pierre Gashema, Anita Ghansah, Stan Hangi, Deus S. Ishengoma, Deus S. Ishengoma, Jean-Baptiste Mazarati, Ayalew Jejaw Zeleke, Philip J. Rosenthal, Abdoulaye A. Djimdé, Abdoulaye A. Djimdé, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jeffrey A. Bailey, Jeffrey A. Bailey

“…While these microhaplotypes were developed based on variations from Sub-Saharan African WGS data, 59.3% (2,529) of SNPs were also common in Southeast Asia. …”
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Epithelial – mesenchymal transition markers, proliferation markers, and cytokine secretion in breast tissue in malignant and benign breast diseases by A. I. Autenshlyus, S. A. Arkhipov, E. S. Mikhaylova, V. V. Arkhipova, A. V. Proskura, N. A. Varaksin, V. V. Lyahovich

“…The parameters of less than 10% of patients with NCBD who fell into other clusters practically coincided with the studied parameters of the ICNT group, which suggests that these patients may form a risk group with the malignancy probability of more than 90%.Conclusion. The data obtained made it possible to develop methodological grounds for assessing the likelihood of breast malignancy in patients with NCBD.…”
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Impact factors and genetic characteristics of head lice infestation in schoolchildren: a cross-sectional study from 2018 to 2023 in central China by Yi-Tian Fu, Yuan-Ping Deng, Yue Xie, Hui-Mei Wang, Yan-Yan Peng, Guo-Hua Liu, Xiang Wu

“…Impact factors for infestation were analyzed using the data collected by a questionnaire. The mt cytb gene sequences of head lice collected in the current study were used for sequence analysis, then were added to the global pool to conduct the phylogenetic analyses. …”
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Individualized evaluation of risk and prognosis in uterine leiomyosarcoma patients with synchronous distant metastases: a real-world retrospective study by Zhongli Liu, Feng Gao, Tao Min, Qianqian Shang, Bin Wang, Jing Pu

“…Subsequently, two practical nomograms were developed and validated to assess the probability of distant metastases and predict survival outcomes for these with distant metastases, respectively.MethodsA real-world retrospective study was carried out using data from patients diagnosed with primary uLMS in the Surveillance, Epidemiology, and End Results (SEER) database spanning the years 2010 to 2015. …”
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Urban–rural disparities in fall risk among older Chinese adults: insights from machine learning-based predictive models by LiHan Lin, LiHan Lin, XiaoYang Liu, CaiHua Cai, YiKun Zheng, Delong Li, GuoPeng Hu

“…Identifying key factors and differences in fall risks, along with developing predictive models, is essential for differentiated and precise interventions in China’s urban and rural older populations.MethodsThe data of 5,876 older adults were obtained from the China Health and Retirement Longitudinal Survey (Waves 2015 and 2018). …”
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The attitude of the unvaccinated children’s parents toward pediatric COVID-19 vaccination in Tabriz, Iran by Nasrin Jafari, Hossein Akbari, Anahita Maghsoodi, Parvin Sarbakhsh

“…A random sample of 400 parents was selected from five healthcare centers using a cluster sampling method in conjunction with the Iranian SIB system. To gather data, a questionnaire was developed based on a comprehensive literature review and interviews with local parents. …”
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Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer by Lijing Gao, Yanbing Li, Chao Qu, Yan Dong, Qingzhen Fu, Haibo Zhou, Ning Zhao, Xianyu Zhang, Da Pang, Yashuang Zhao

“…Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC), and prognostic value was evaluated using Cox regression analysis. A multiplex digital droplet PCR (mddPCR) assay was developed to simultaneously detect cg06268921 and cg23247845 in cfDNA from TNBC (n = 33) and non-TNBC (n = 80) patients. …”
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Framework Construction and Dynamic Characteristics of Spring Low-Temperature Disasters Affecting Winter Wheat in the Huang-Huai-Hai Region, China by Meixuan Li, Zhiguo Huo, Qianchuan Mi, Lei Zhang, Yi Wang, Rui Kong, Mengyuan Jiang, Fengyin Zhang

“…In order to ensure the timely, precise, and comprehensive capture of disaster processes, we have developed a dynamic evaluation framework for winter wheat spring LTD in the Huang-Huai-Hai (HHH) region, driven by meteorological data. …”
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Remnant cholesterol in early pregnancy as a predictor of gestational diabetes mellitus beyond triglyceride levels: a retrospective cohort study by Xiang-Xiang Li, Jia-Yi Zhang, Si-Yuan Chen, Xiao-Fei Wu, Chun-Fang Ma, Hao Shen

“…Methods We performed a retrospective cohort study involving pregnant women admitted to the Suzhou Ninth Hospital affiliated to Soochow University. Data were obtained from the electronic medical record system. …”
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Nomogram based on pan-immune-inflammation value to predict short-term prognosis in spontaneous intracerebral hemorrhage by Shuai Wang, Shuai Wang, Wei Zhang, Jingjing Li, Jingjing Li, Xinxin Yang, Yuqiao Wang, Yuqiao Wang

“…IntroductionThe aim of this study was to investigate the impact of the Pan-Immune-Inflammation Value (PIV) on the prognosis of spontaneous intracerebral hemorrhage (ICH) and to develop and validate a nomogram for identifying patients with a poor prognosis following ICH.MethodsWe retrospectively collected the clinical data of 742 patients with ICH admitted to the Affiliated Hospital of Xuzhou Medical University from September 2018 to March 2024. …”
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