Cognition and behavior in adults with neurofibromatosis type 1 by Anja Bos-Roubos, Anja Bos-Roubos, Anja Bos-Roubos, Hanneke van Leeuwen, Hanneke van Leeuwen, Hanneke van Leeuwen, Ellen Wingbermühle, Ellen Wingbermühle, Ellen Wingbermühle, Ellen Wingbermühle, Louisa van den Bosch, Lindsey Ossewaarde, Walter Taal, Walter Taal, Laura de Graaff, Laura de Graaff, Laura de Graaff, Jos Egger, Jos Egger, Jos Egger, Jos Egger, Jos Egger

“…Cognition and behavior was tested against population means constructed by bootstrapping.ResultsPerformance on the cognitive measures oral reading speed, visuospatial copying, visuospatial immediate recall, visual learning/imprinting, and visual memory immediate recall in the NF1 group were lower than normative means. …”
Get full text

Comparison of the TNM9th and 8th editions for localized and locally advanced anal squamous cell carcinoma treated nonsurgically and proposal of a new stage grouping system by Aihong Zheng, Yiwen Wang, Shuang Li, Yingjie Wang, Hong'en Xu, Jieni Ding, Bingchen Chen, Tao Song, Lei Lai

“…Abstract Objective To compare the survival discrimination of the TNM9th and 8th editions for localized and locally advanced anal squamous cell carcinoma (ASCC) treated nonsurgically and suggest a simple revised staging system with data from the Surveillance, Epidemiology, and End Results (SEER) database. …”
Get full text

Key motor and non-motor features in early dementia with Lewy bodies by Anna Planas-Ballvé, Anna Planas-Ballvé, José Rios, Lourdes Ispierto, Mireia Gea, Laia Grau, Marta Jiménez, Cynthia Cáceres, Sílvia Martínez, Katrin Beyer, Ramiro Álvarez, Pau Pastor, Dolores Vilas, Dolores Vilas

“…Demographic and clinical data were collected, and motor and non-motor symptoms were assessed using structured interviews and validated scales and questionnaires.ResultsA total of 107 participants were included (23 DLB, 27 PD, 26 AD, and 31 controls). …”
Get full text

Machine Learning Model Based on Prognostic Nutritional Index for Predicting Long‐Term Outcomes in Patients With HCC Undergoing Ablation by Nan Zhang, Ke Lin, Bin Qiao, Liwei Yan, Dongdong Jin, Daopeng Yang, Yue Yang, Xiaohua Xie, Xiaoyan Xie, Bowen Zhuang

“…Methods From January 2009 to December 2019, we analyzed data from 848 primary HCC patients who underwent local ablation. …”
Get full text

Does the number of drain tubes influence the formation of postoperative spinal epidural hematoma following biportal endoscopic unilateral laminotomy for bilateral decompression (BE... by Zhuolin Zhong, Jingjing Ying, Shaohua Zhang, Kaili Cai, Xiaowei Jing, Zhengyu Xu, Lejian Jiang, Tianxin Wu, Guojun Wei, Qingfeng Hu

“…Patients were divided into two groups: Group A (one drain tube) and Group B (two drain tubes). Demographic data were collected, including preoperative visual analog scale (VAS) scores for leg pain and preoperative blood pressure (BP). …”
Get full text

Opioid versus opioid-free analgesia after surgical discharge: protocol for a systematic review and meta-analysis by Charbel El-Kefraoui, Ghadeer Olleik, Marc-Aurele Chay, Araz Kouyoumdjian, Philip Nguyen-Powanda, Fateme Rajabiyazdi, Uyen Do, Alexa Derksen, Tara Landry, Alexandre Amar-Zifkin, Agnihotram V. Ramanakumar, Marc-Olivier Martel, Gabriele Baldini, Liane Feldman, Julio F Fiore Jr

“…Teams of reviewers will, independently and in duplicate, assess eligibility, extract data and evaluate risk of bias. Our main outcomes of interest are pain intensity and postoperative vomiting. …”
Get full text

Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes by Sophia Grotz, Jessica Schäfer, Kirsten A Wunderlich, Zdenka Ellederova, Hannah Auch, Andrea Bähr, Petra Runa‐Vochozkova, Janet Fadl, Vanessa Arnold, Taras Ardan, Miroslav Veith, Gianluca Santamaria, Georg Dhom, Wolfgang Hitzl, Barbara Kessler, Christian Eckardt, Joshua Klein, Anna Brymova, Joshua Linnert, Mayuko Kurome, Valeri Zakharchenko, Andrea Fischer, Andreas Blutke, Anna Döring, Stepanka Suchankova, Jiri Popelar, Eduardo Rodríguez‐Bocanegra, Julia Dlugaiczyk, Hans Straka, Helen May‐Simera, Weiwei Wang, Karl‐Ludwig Laugwitz, Luk H Vandenberghe, Eckhard Wolf, Kerstin Nagel‐Wolfrum, Tobias Peters, Jan Motlik, M Dominik Fischer, Uwe Wolfrum, Nikolai Klymiuk

Get full text

Development and validation of an early diagnosis model for severe mycoplasma pneumonia in children based on interpretable machine learning by Si Xie, Mo Wu, Yu Shang, Wenbin Tuo, Jun Wang, Qinzhen Cai, Chunhui Yuan, Cong Yao, Yun Xiang

“…Methods The study comprised 597 SMPP patients aged between 1 month and 18 years. Clinical data were selected through Lasso regression analysis, followed by the application of eight machine learning algorithms to develop early warning model. …”
Get full text

Test-retest reliability of diffusion kurtosis imaging metrics in the healthy adult brain by Liu-Yang Wu, Yao Xu, Lan-Lan Chen, Wen-Rui Yang, Yan Li, Song-An Shang, Xian-Fu Luo, Wei Xia, Jing Xia, Hong-Ying Zhang

“…Although the DKI reliability of GM regions varied, the default mode and visual areas consistently demonstrated the highest ICC reliability for a series of kurtosis-related metrics. …”
Get full text

Ice loss detection of glacierets in the Desert and Central Andes of Chile between 2018 and 2023 by Felipe Ugalde, Felipe Ugalde, Helena Valenzuela-Astudillo, Helena Valenzuela-Astudillo, Helena Valenzuela-Astudillo, Martina Toledo, Martina Toledo, Javiera Carrasco, Javiera Carrasco, Lucas Ruiz, Lucas Ruiz, Ashley Apey, Diego Pinto, Diego Pinto, Cedomir Marangunic

“…We validate our results through a visual inspection for all the small glacierets (area below 0.01 km2) using high-resolution optical imagery for the period 2018–2023. …”
Get full text

The potential for dementia prevention in Brazil: a population attributable fraction calculation for 14 modifiable risk factorsResearch in context by Claudia K. Suemoto, Wyllians V. Borelli, Ismael L. Calandri, Laiss Bertola, Raphael M. Castilhos, Paulo Caramelli, Ricardo Nitrini, Sonia M.D. Brucki, Jerson Laks, Naaheed Mukadam, Gill Livingston, Cleusa P. Ferri

“…The three risk factors with the highest PAFs were less education (9.5%, 95% CI = 8.9–10.1), untreated visual loss (9.2%, 95% CI = 8.6–9.8), and midlife depression (6.3%, 95% CI = 5.8–6.8). …”
Get full text

Effect of fusion and arthroplasty for cervical degenerative disc disease in patients with physically demanding occupations by Harjot Uppal, MBA, George Abdelmalek, MD, Neil Patel, MD, Daniel Coban, MD, Stuart Changoor, MD, Nikhil Sahai, MD, Kumar Sinha, MD, Ki Hwang, MD, Arash Emami, MD

“…Participants were followed for a minimum of 2 years. Data collected included demographic details, perioperative events, and complication rates. …”
Get full text

Predicting the risk of postoperative avascular necrosis in patients with talar fractures based on an interpretable machine learning model by Jian Zhang, Jian Zhang, Jian Zhang, Jihai Xu, Jihai Xu, Jiapei Yu, Jiapei Yu, Jiapei Yu, Hong Chen, Hong Chen, Xin Hong, Songou Zhang, Xin Wang, Xin Wang, Chengchun Shen, Chengchun Shen, Chengchun Shen

“…PurposeThis study aims to develop and validate an interpretable machine learning model for predicting avascular necrosis (AVN) following talar fracture, thereby aiding in personalized prevention and treatment.MethodsA retrospective cohort study included patients undergoing surgical intervention for talar fractures at Ningbo No.6 Hospital between January 2018 and December 2023. Multidimensional data encompassing demographic characteristics, fracture-related variables, surgery-related parameters, and follow-up information were collected. …”
Get full text

Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics by Nils A. Koch, Benjamin W. Corrigan, Michael Feyerabend, Roberto A. Gulli, Michelle S. Jimenez-Sosa, Mohamad Abbass, Julia K. Sunstrum, Sara Matovic, Megan Roussy, Rogelio Luna, Samuel A. Mestern, Borna Mahmoudian, Susheel Vijayraghavan, Hiroyuki Igarashi, Kartik S. Pradeepan, William J. Assis, J. Andrew Pruszynski, Shreejoy Tripathy, Jochen F. Staiger, Guillermo Gonzalez-Burgos, Andreas Neef, Stefan Treue, Stefan Everling, Wataru Inoue, Anmar Khadra, Julio C. Martinez-Trujillo

“…To address this, we recorded macaque lateral prefrontal cortex (LPFC) neurons in vivo during a visually guided saccade task and in vitro in brain slices. …”
Get full text

Non-contrast enhanced functional lung MRI in children: report on 900 own measurements using matrix-pencil decomposition (MP-) MRI by Carmen Streibel, Carmen Streibel, Carmen Streibel, Grzegorz Bauman, Grzegorz Bauman, Oliver Bieri, Oliver Bieri, Orso Pusterla, Orso Pusterla, Orso Pusterla, Enno Stranzinger, C. Corin Willers, Marion Curdy, Carmen Casaulta, Bettina Sarah Frauchiger, Insa Korten, Sophie Yammine, Yasmin Salem, Philipp Latzin, Elisabeth Kieninger

“…The exemplary cases from different disease groups illustrate its value in the clinical setting. In conclusion, visualizing regional functional deficits and respective underlying pathophysiological nature of lung impairment seems promising for increasing use of NCE-MRI in the future.…”
Get full text

Deep anterior chamber depth may be a risk factor for axial length growth in children by Huijie Cao, Huijie Cao, Yongguo Xiang, Yongguo Xiang, Hong Cheng, Hong Cheng, Kexin Sun, Kexin Sun, Shijie Zheng, Shijie Zheng, Miaomiao Du, Miaomiao Du, Ning Gao, Ning Gao, Tong Zhang, Xin Yang, Jiuyi Xia, Wenjuan Wan, Wenjuan Wan, Ke Hu, Ke Hu

“…Six months later, the above examinations were repeated to obtain follow-up data. Visual habits questionnaire was gained to analyze the correlation between the AL growth and vision-related behavior.ResultsA total of 417 students from Chongqing were enrolled in this study. …”
Get full text

Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials by Zhaokai Jin, Yi Tang, Hua Huang, Lei Chen, Zhongyi Zhang, Tianyou Ma, Zhengming Wang, Hai Su, Haojing Zhou, Shuaijie Lv, Peijian Tong

“…We extracted the required data according to the Cochrane Handbook for Systematic Reviews of Interventions. …”
Get full text

Modified double-row suture bridge technique for anterior colliculus fractures combined with deltoid ligament injury: a retrospective study by Jianlong Ni, Zhihao Chen, Wang Wei, Ruiying Li, Dazhi Wang, Dongjian Wang, Zenan Tian, Zhikun Jia, Qichun Song, Meng Feng, Zhibin Shi

“…For clinical outcome evaluation, objective data are presented through clinical examination findings; radiographic assessments, including X-rays and computed tomography (CT); and follow-up analysis utilizing American Orthopaedic Foot & Ankle Society ankle‒hindfoot (AOFAS) scores, Olerud Molander Ankle Scores (OMAS), and visual analogue scale (VAS) scores. …”
Get full text

Prevention of extubation failure in neurocritical care patients with residual disorder of consciousness: the Brain-Injured Patients Extubation Readiness (BIPER) study protocol for... by Emmanuel Futier, Bruno Pereira, Russell Chabanne, Elodie Caumon, Dominique Morand, Audrey De Jong, Jean-Michel Constantin, Matthieu Jabaudon, Thomas Godet, Benjamin Andanson, Pierre Borrel, Leo Astier, Nathalie Bourguignon, Lise Laclautre

Get full text

Clinical characteristics and risk factors of bacillary layer detachment in central serous chorioretinopathy: a comparative multicenter study by Antonio M. Casella, Raphaela M. Fuganti, Ahmad M. Mansour, José Ignácio Fernández-Vigo, Suthasinee Sinawat, Ali Osman Saatci, Jay Chhablani, Arman Zarnegar, Juliana Prazeres, Igor Kozak, Lorenzo López Guajardo, Michel E. Farah, Claudio Zett, Francisco Rodriguez, William E. Smiddy, Janet L. Davis, Philip J. Rosenfeld, Stephen G. Schwartz, Luiz H. Lima, Maurício Maia

“…Methods This observational, retrospective, multicenter case–control study collected data from 12 retina centers worldwide on patients with central serous chorioretinopathy (CSC) from December 1, 2022, to April 1, 2023. …”
Get full text