Exploring the interaction effects of subclinical hypothyroidism and major depressive disorder on brain networks by Shuai Zhao, Jindan Wu, Xiaomei Liu, Yishan Du, Xiaoqin Wang, Yi Xia, Hao Sun, Haowen Zou, Xumiao Wang, Zhilu Chen, Rui Yan, Hao Tang, Qing Lu, Zhijian Yao

“…This study aimed was to investigate the neurological mechanisms underlying this co-occurrence using a data-driven approach to analyze brain activity patterns. …”
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The cellular and extracellular proteomic signature of human dopaminergic neurons carrying the LRRK2 G2019S mutation by Felix Knab, Giambattista Guaitoli, Mohamed Ali Jarboui, Felix von Zweydorf, Fatma Busra Isik, Franziska Klose, Anto Praveen Rajkumar, Thomas Gasser, Thomas Gasser, Christian Johannes Gloeckner

“…We isolated extracellular vesicles and neuronal cell lysates and characterized their proteomic signature using data-independent acquisition proteomics. Then, we performed differential expression analysis to identify dysregulated proteins in the mutated line. …”
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A Comparison of Retinoblastoma Cases in the Philippines by Roland Joseph D. Tan, MD, MS, MIH, Aldous Dominic C. Cabanlas, MD, Benedicto Juan E. Aguilar, MD, Gabrielle S. Evangelista, MD, John Michael Maniwan, MD, Andrei P. Martin, MD, Calvin Y. Martinez, MD, John Alfred A. Lim, MD, Rena Ivy Bascuna, MD, Rachel M. Ng, MD, MPH, Kevin B. Agsaoay, MD, Kris Zana A. Arao, MD, Ellaine Rose V. Apostol, MD, Mara Augustine S. Galang, MD, Josemaria M. Castro, MD, Kimberley Amanda K. Comia, MD, Gary John V. Mercado, MD, Patricia E. Cabrera, MD, Paulita Pamela P. Astudillo, MD, Rolando Enrique D. Domingo, MD, Josept Mari S. Poblete, MD, PhD, Charmaine Grace M. Cabebe, MD, Adriel Vincent R. Te, MD, Melissa Anne S. Gonzales, MD, Jocelyn G. Sy, MD, Beltran Alexis A. Aclan, MD, Jayson T. So, MD, Fatima G. Regala, MD, Beatriz M. Prieto, MD

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Changes in glycinergic neurotransmission alter mammalian retinal information processing by Anneka Joachimsthaler, Anneka Joachimsthaler, Katharina Hauf, Katharina Hauf, Anja Armbruster, Shiri Zayit-Soudry, Efrat Naaman, Ido Perlman, Rina Leibu, Alina Kurolap, Hagit Baris Feldman, Hagit Baris Feldman, Jan Kremers, Jan Kremers, Volker Eulenburg, Volker Eulenburg, Volker Eulenburg

“…However, the impact of loss of glycinergic neurotransmission on retinal signal processing and visually guided behavior, has not yet been elucidated. …”
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Number, treatment, and mortality of paediatric pelvic ring fractures in two level 1 trauma centres in the Netherlands: a multicentre retrospective cohort study by Anna H. M. Mennen, Esther M. M. Van Lieshout, Frank W. Bloemers, Abby E. Geerlings, Meike E. Van Haeringen, Justus R. De Jong, Michael H. J. Verhofstad, Mark G. Van Vledder, Daphne Van Embden

“…Methods: This multicentre, retrospective cohort study analyzed paediatric patients (aged ≤ 18 years) with pelvic ring fractures treated between 2001 and 2021 at two level 1 trauma centres. Data on patient demographics, injury characteristics, treatment approaches, and outcomes were collected, and visual trend analysis was conducted to identify patterns. …”
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Combining patient-reported outcome measures to screen for active disease in rheumatoid arthritis and psoriatic arthritis by Annette H M van der Helm-van Mil, Pascal H P de Jong, Paco M J Welsing, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Paul Baudoin, Lindy-Anne Korswagen, Selinde V J Snoeck Henkemans, Agnes E M Looijen, Gonul Hazal Koc

“…In PsA, these percentages are 41% and 4%, respectively.Conclusion A combination of general health, HAQ-DI, EQ-5D and pain could aid as a screening tool for active disease in patients with RA and PsA. These data could help facilitate remote monitoring of RA and PsA patients in the future.Trial registration numbers ISRCTN26791028, NTR2754.…”
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Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…Postoperative pancreatitis developed in 2 cases (5.9%, 2/34), and hyperamylasemia occurred in 5 cases (14.7%, 5/34). The postprocedure visual analogue scale (VAS) score for abdominal pain significantly decreased from 6 to 1 (P < 0.001). …”
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Feasibility and safety of transvaginal natural orifice transluminal endoscopic surgery (V-NOTES) panhysterectomy: a polycentric retrospective study by Panlian Qian, Weimin Chen, Bin Su, Yao Chen, Wulin Shan, Huimin Tang, Weiwei Wei, Huihui Wang, Bairong Xia, Jiming Chen

“…Methods A retrospective analysis was conducted on the data of 75 patients who underwent panhysterectomy for hysteromyoma in the Department of Obstetrics and Gynecology of Tongxiang Maternal and Child Health Hospital; Department of Gynecology, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University and Department of Gynecology, The First Affiliated Hospital of USTC from June 2019 to June 2020. …”
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Outcomes of arthroscopic one-stage repair and reconstruction of Schenck II–IV knee dislocations with multiple ligament injuries: a single-center study by Shengwen Xiang, Zhen Hu, Zihao Ren, Guangqing Cai, Zhijiang Ao, Weiguo Hu, Yangbo Liu, Xing Li, Licheng Wei

“…Methods We retrospectively reviewed the data of patients with Schenck II–IV knee dislocations and multiple ligament injuries treated in our hospital during 2019–2022. …”
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The influence of type 2 diabetes mellitus on clinical manifestations of osteoarthritis by E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, E. A. Strebkova, E. P. Sharapova, N. M. Savushkina, K. M. Mikhailov, T. A. Raskina, I. B. Vinogradova, E. N. Otteva, E. V. Zonova, O. N. Anoshenkova, A. M. Lila

“…An individual record card was filled out for each patient, it contained anthropometric parameters, medical history and clinical examination data, knee pain assessment using a visual analogue scale (VAS), WOMAC, parameters of KOOS questionnaire and patient's global assessment of health. …”
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Predictive Factors and Nomogram for 30-Day Mortality in Heatstroke Patients: A Retrospective Cohort Study by Anxin Li, Yuchen Zhang, Xiaoshi Zhang, Zixiao Duan, Yan Chen, Xiaoyan Jiang, Wuquan Deng

“…Methods: We conducted a retrospective cohort study, analyzing the clinical data of 203 HS patients between May 2016–September 2024. …”
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SPING Block Analgesia in Non-Operative Management of Proximal Femur Fractures in Older Adults Living with Frailty: A Retrospective Cohort Study by Miriam W. A. van der Velden, Thamar Kroes, Nick J. G. Visschers, Frank P. J. F. de Loos, Pleun Janssens, Bart Spaetgens, Miriam C. Faes, Marieke H. J. van den Beuken-van Everdingen, Arnela Suman

“…The patient living situation was visualized with a Sankey diagram. Changes in pain scores and opioid use were assessed using the Wilcoxon Signed Rank test. …”
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Knowledge, Attitudes, and Practices of Parents Regarding Ophthalmological Screening of Preschool-Aged Children in Jazan, Saudi Arabia by Mohamed Salih Mahfouz, Samy Shaban Mahmoud, Saleha Qaseem Haroobi, Latifah Mohammed Bahkali, Shahad Ibrahim Numan, Areen Mohsen Taheri, Ohoud Ali Hakami, Orjuwan Adel Zunquti, Sarah Mohammed Khered

“…The survey tool consisted of four main sections: socio-demographic data, knowledge about eye care, attitudes toward eye screening, and eye care practices. …”
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Exogenous Application of 1-Aminocyclopropane-1-carboxylic Acid as a New Strategy to Trigger the Color Development of Table Grapes Grown in Subtropics by Aline Cristina de Aguiar, Fábio Yamashita, Renata Koyama, Bruna Evelise Bosso Caetano, Carlos Akira Komoli Utiamada, Sergio Ruffo Roberto

“…The data were subjected to analysis of variance, and means were compared by Tukey’s test at 5% significance using R-Studio software. …”
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Nutritional and Technological Benefits of Pine Nut Oil Emulsion Gel in Processed Meat Products by Berik Idyryshev, Almagul Nurgazezova, Zhanna Assirzhanova, Assiya Utegenova, Shyngys Amirkhanov, Madina Jumazhanova, Assemgul Baikadamova, Assel Dautova, Assem Spanova, Assel Serikova

“…Functional improvements were observed in emulsion stability, cooking yield, and water retention. Textural and visual characteristics remained within acceptable sensory thresholds. …”
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Use of MedSafer electronic decision support for deprescribing in patients on hemodialysis: a qualitative study by Émilie Bortolussi-Courval, Jimmy J. Lee, Emilie Trinh, Lisa M. McCarthy, M. Battistella, Ryan Hanula, Todd C. Lee, Kathleen Rice, Emily G. McDonald

“…Interviews with participating nephrologists were conducted and transcribed by the study lead. Afterwards, data was coded and analyzed thematically with a focus on their perspective on participating in a quality improvement project during their clinical practice. …”
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CLINICAL EFFECTIVENESS OF NEUROTRANSMITTERS PATIENTS WITH PRIMARY GLAUCOMA VEGF INHIBITOR IN PATIENTS WITH CHOROIDAL NEOVASCULARIZATION CAUSED BY DEGENERATIVE MYOPIA by L. P. Danilova, V. V. Egorov, G. P. Smolyakova, L. P. Emanova, D. A. Povalyaeva

“…After 3 months from the beginning of observation according to FAG and OCT data relapse of activity of myopic CNV occurred in 5 patients (15.6%) after a single injection, and in 2 patients (6.3%) — after a double injection of ranibizumab. …”
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Environmental monitoring and spatiotemporal trend analysis of avian influenza virus in Xinjiang, 2021-2023 by Zhe Yin, Fuerhati Wushouer, Jia Huang, Yan Dong, Qi Wang, Xiapikatijiang Aihaiti, Xiayidanmu Abudusaimaiti, Yuanyuan Ma, Zihan Chen, Ruiying Qiu, Quanxi Li, Zhenguo Gao

“…Real-time RT-PCR was used to detect nucleic acid for H5, H7, and H9 subtypes. Data were statistically analyzed using Excel and SPSS, and spatial distribution was visualized through Kriging interpolation using ArcGIS. …”
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Wheat Powdery Mildew Severity Classification Based on an Improved ResNet34 Model by Meilin Li, Yufeng Guo, Wei Guo, Hongbo Qiao, Lei Shi, Yang Liu, Guang Zheng, Hui Zhang, Qiang Wang

“…Subsequently, the optimal training strategy was determined through hyperparameter tuning experiments, and GrabCut-based background processing along with data augmentation were introduced to enhance model robustness. …”
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Lactylation and its roles in diseases: a systematic bibliometric exploration of the research landscape by Mengjia Li, Mengjia Li, Yuhang Liu, Chuhan Jiang, Shiyu Zhang, Mengyu Nan, Jiaxi Liu, Yangyang Han, Yangyang Han

“…Excel tracked publication trends, VOSviewer generated author density maps, and CiteSpace visualized collaboration networks, co-cited references, and keyword clusters. …”
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