Assessing ResNeXt and RegNet Models for Diabetic Retinopathy Classification: A Comprehensive Comparative Study by Samara Acosta-Jiménez, Valeria Maeda-Gutiérrez, Carlos E. Galván-Tejada, Miguel M. Mendoza-Mendoza, Luis C. Reveles-Gómez, José M. Celaya-Padilla, Jorge I. Galván-Tejada, Antonio García-Domínguez

“…The experimental design involved partitioning the data into training (70%), validation (20%), and testing (10%) sets. …”
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Targeting Nanotherapeutics for Highly Efficient Diagnosis and Treatment of Systemic Lupus Erythematosus through Regulation of Immune Response by Ting Liu, Zhiming Lin, Xi Zhang, Yu Yang, Guanning Huang, Yanzi Yu, Bin Xie, Lizhen He, Tianfeng Chen

“…Moreover, MSNs‐DNA can also help visualize the distribution of anti‐dsDNA antibodies in the lesions of the kidney. …”
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In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma by Kathrin Philipp‐Abbrederis, Ken Herrmann, Stefan Knop, Margret Schottelius, Matthias Eiber, Katharina Lückerath, Elke Pietschmann, Stefan Habringer, Carlos Gerngroß, Katharina Franke, Martina Rudelius, Andreas Schirbel, Constantin Lapa, Kristina Schwamborn, Sabine Steidle, Elena Hartmann, Andreas Rosenwald, Saskia Kropf, Ambros J Beer, Christian Peschel, Hermann Einsele, Andreas K Buck, Markus Schwaiger, Katharina Götze, Hans‐Jürgen Wester, Ulrich Keller

“…Based on these highly encouraging data on clinical PET imaging of CXCR4 expression in a cohort of MM patients, we conclude that [68Ga]Pentixafor PET opens a broad field for clinical investigations on CXCR4 expression and for CXCR4‐directed therapeutic approaches in MM and other diseases.…”
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A Framework for Cervical Cancer Elimination in Low-and-Middle-Income Countries: A Scoping Review and Roadmap for Interventions and Research Priorities by Michelle B. Shin, Gui Liu, Nelly Mugo, Nelly Mugo, Patricia J. Garcia, Patricia J. Garcia, Darcy W. Rao, Darcy W. Rao, Cara J. Broshkevitch, Linda O. Eckert, Linda O. Eckert, Leeya F. Pinder, Leeya F. Pinder, Judith N. Wasserheit, Judith N. Wasserheit, Judith N. Wasserheit, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas

“…Effective prevention methods include HPV vaccination, screening using visual inspection and HPV testing, and thermocoagulation. …”
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The overgrowth of structure-function coupling in premature brain during infancy by Rong Wang, Tianyu Fang, Yue Zhang, Yue Cheng, Chunfang Wang, Yuanyuan Chen, Qiuyun Fan, Xin Zhao, Dong Ming

“…In this study, the multimodal MRI data from the dHCP database were used to investigate the coupling between brain structure and function in infants, with a particular focus on how prematurity influences this relationship. …”
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AI-driven MRI analysis reveals brain atrophy patterns in benign relapsing-remitting multiple sclerosis by M. Niiranen, M. Niiranen, P. Bendel, P. Bendel, J. Koikkalainen, J. Lötjönen, T. Selander, E. Solje, E. Solje, P. Hartikainen, S. Simula, R. Vanninen, R. Vanninen, A. M. Portaankorva

“…In this study, we aimed to investigate the brain atrophy patterns related to benign relapsing-remitting MS (BRRMS), particularly regarding location and extent.MethodsWe analyzed global and regional gray matter (GM) and white matter (WM) volumes, WM lesion load, corpus callosum index (CCI) and corpus callosum area (CCA) in well-defined benign relapsing-remitting MS patients (BRRMS, n = 35) compared to healthy controls (HC, n = 35). Imaging data were analyzed using an AI-based volumetric analysis MRI (cNeuro®) and confirmed visually by an experienced neuroradiologist, ensuring robust validation.ResultsTotal brain tissue volume was significantly smaller in patients with BRRMS compared to HC (p < 0.001), but the cortical (p = 0.011) and cerebral (p = 0.002) GM volumes, as well as cingulate gyrus (p=0.032) and entorhinal area volumes (p < 0.001), were larger in BRRMS. …”
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Impact of IYCF practices, as measured by national nutrition surveys from 2018 to 2022, on stunting and under-5 survival in Burkina Faso: a LiST analysis by Natacha Kere, Ella W. R. Compaore, Ella W. R. Compaore, Youssouf Keita, Daniel S. Ouedraogo, Souleymane Tirogo, Estelle A. Bambara, Z. Thierry Coulibaly, Mamoudou H. Dicko

“…Nevertheless, 920 lives were saved nationwide, 232 in the Center region and 202 in the Sahel region.ConclusionThe study highlighted the need to strengthen the implementation of IYCF interventions, coupled with a significant improvement in the quality of NNS data collection, given the up and down nature of the indicators, which makes them difficult to use for decision-making.…”
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Telemedicine for under-resourced patients with systemic lupus erythematosus: a qualitative study exploring the views and experiences of patients and their healthcare team by Savannah Bowman, Sandeep K. Agarwal, Keshia C. Ferguson, Maryjo J. Maliekel, Maria A. Lopez-Olivo, Maria E. Suarez-Almazor, Maria I. Danila, Maria I. Danila, Jinoos Yazdany, Sebastian Bruera

“…Interview content was coded using inductive and deductive approaches. Data collected proceeded until thematic saturation was reached. …”
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Quality of Life and Well‐Being in Adults With Fontan Physiology: Findings From the Australian and New Zealand Fontan Registry Quality of Life Study by Kate H. Marshall, Yves d'Udekem, David S. Winlaw, Diana Zannino, David S. Celermajer, Robert Justo, Ajay Iyengar, Rachael Cordina, Gary F. Sholler, Susan R. Woolfenden, Nadine A. Kasparian

“…Health‐related QOL was assessed using the Pediatric Quality of Life Inventory, and global QOL was assessed using a visual analog scale (0–10). Participants reported lower total health‐related QOL (P<0.001), as well as lower physical (P<0.001) and social (P=0.002) functioning compared with normative data. …”
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Investigating the Effect of Reducing the Signs and Symptoms of Lid Wiper Epitheliopathy in Patients With Dry Eye Disease With Perfluorohexyloctane by Chris Lievens, OD, MS, PhD, FNAP, FAAO, Andrew D. Pucker, OD, PhD, FAAO, Quentin Franklin, BS, Stephen M. Montaquila, OD, FAAO, Brad Giedd, OD, MS, FAAO, Gina Wesley, OD, MS, FAAO, Morgan Bromley, PhD, Zackarias Coker, MS, John Meyers, MS, Marta Vianya-Estopa, PhD

“…Objective: To examine the potential of using perfluorohexyloctane for reducing the signs and symptoms of lid wiper epitheliopathy (LWE). Methods: Data were collected at 4 visits spanning 2 months. …”
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Histological Grade, Tumor Breadth, and Hypertension Predict Early Recurrence in Pediatric Sarcoma: A LASSO-Regularized Micro-Cohort Study by Alexander Fiedler, Mehran Dadras, Marius Drysch, Sonja Verena Schmidt, Flemming Puscz, Felix Reinkemeier, Marcus Lehnhardt, Christoph Wallner

“…Forty-six baseline variables were extracted per patient, including clinical, histological, and comorbidity data. Tumor recurrence was the primary binary endpoint. …”
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Predicting peripartum depression using elastic net regression and machine learning: the role of remnant cholesterol by Hongxu Chen, Denglan Wang, Juanjuan Shen, Baoyan Guo, Chun Song, Duo Ma, Yan Wu, Guohui Liu, Guangxue Chen, Yan Ni, Tiantian Kong, Fan Wang

“…After excluding incomplete or incorrect baseline data, 325 participants were ultimately included in the study. …”
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‘Water is life’: developing community participation for clean water in rural South Africa by Kathleen Kahn, Rhian Twine, Jennifer Hove, Lucia D'Ambruoso, Denny Mabetha, Maria van der Merwe, Peter Byass, Sonto Khosa, Sophie Witter

“…Thematic analysis of narrative and visual data was performed.Results Repeated and prolonged periods when piped water is unavailable were reported, as was unreliable infrastructure, inadequate service delivery, empty reservoirs and poor supply exacerbated by droughts. …”
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Standardized low-resolution brain electromagnetic tomography does not improve EEG Alzheimer's disease assessment by Wolfgang Frühwirt, Martin Mairhofer, Andreas Hahn, Heinrich Garn, Markus Waser, Reinhold Schmidt, Thomas Benke, Peter Dal-Bianco, Gerhard Ransmayr, Dieter Grossegger, Stephen Roberts, Georg Dorffner

“…Finally, these findings do not diminish the value of 3D source localization for visual EEG inspection.…”
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Neuroadaptive changes in brain structural–functional coupling among pilots by Xi Chen, Qingbin Meng, Qingsong Song, Peiran Xu, Shicong Zhang, Donglin Huang, Qi Chu, Jiamin Fan, Cheng Luo, Xiuyi Li

“…However, prior research has predominantly focused on identifying structural and functional differences in the brain, while the relationship between structure and function remains insufficiently elucidated.MethodsThis study collected T1-weighted structural magnetic resonance imaging (MRI), resting-state functional MRI (rs-fMRI), and diffusion tensor imaging (DTI) data from 47 pilots and 38 matched controls. Structural–functional coupling (SFC) strength was quantified using the Structural Decoupling Index (SDI) based on graph signal processing (GSP). …”
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Effects of gut microbiota on cognitive impairment in Parkinson’s disease: a comprehensive Mendelian randomization and case–control study by Yukun Feng, Yukun Feng, Qi Chang, Hao Zhou, Wei Zhang, Wei Zhang, Ling Xie, Xueyang Deng, Xueyang Deng, Tao Chen, Tao Chen, Weiguo Liu

“…However, the relationship between the gut microbiome (GM) and PD dementia (PDD) remains debated, with their causal effects and underlying mechanisms not yet fully understood.MethodsUtilizing data from large-scale genome-wide association studies (GWASs), this study applied bidirectional and mediating Mendelian randomization (MR) to investigate the causal relationship and underlying mechanisms between the GM and PDD. …”
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Evaluation of blood flow in arteritic anterior ischemic optic neuropathy using laser speckle flowgraphy: A case series by Chiaki Yamaguchi, Naoki Kiyota, Noriko Himori, Takahiro Oshima, Takayuki Takeshita, Kazuko Omodaka, Satoru Tsuda, Toru Nakazawa

“…This disease results in significant ocular blood flow (BF) impairment, though data on ocular hemodynamics are limited. Methods: This observational case series enrolled four patients treated for AAION (age: 81.8 ± 7.8 years; male to female ratio: 3:1) who underwent laser speckle flowgraphy (LSFG) scanning at the initial visit and after steroid treatment in both eyes. …”
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The Effect of Rosa Foetida Extract along with Self-Care Education on Primary Dysmenorrhea: A Prospective Randomized Clinical Trial by Fatemeh Shabani, Shabnam Omidvar, Parvin Sajadi Kaboudi, Hajar Pasha, Soraya Khafri, Hossein Najafzadehvarzi, Fatemeh Nasiri-Amiri, Mahbobeh Faramarzi, Zinatossadat Bouzari

“…The third group received no medication. Data were collected through questionnaires including demographic characteristics questionnaire, a visual analogue scale (VAS), menstrual distress scale questionnaire (MDQ), dysmenorrhea self-care behaviors scale questionnaire (DSCS), and Pictorial Blood Loss Assessment Chart (PBAC). …”
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A prediction model for moderate to severe pain in primary hepatic carcinoma after chemotherapy: a multi-center prospective case‒control study by Siting Huang, Aiqin Liu, Xiaoruo Yu, Zhifeng Qiu, Guizhen Weng, Dun Liu, Yan Wang, Yan Zhuo, Liuqing Yao, Mei Yang, Hui Lin, Xi Ke

“…Population was PHC patients who received chemotherapy from April to August to 2024 in three grade 3 and first-class hospital. Data were collected in two periods (on the day of admission and within 24 h of chemotherapy). …”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…<b>Methods</b>: The review methodology was co-designed with four caregivers. Data sources were the peer-reviewed scientific literature and a call for innovations. …”
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