A refined analysis of Neanderthal-introgressed sequences in modern humans with a complete reference genome by Shen-Ao Liang, Tianxin Ren, Jiayu Zhang, Jiahui He, Xuankai Wang, Xinrui Jiang, Yuan He, Rajiv C. McCoy, Qiaomei Fu, Joshua M. Akey, Yafei Mao, Lu Chen

“…While studies on archaic admixture in modern humans have so far relied on the GRCh37 reference due to the availability of archaic genome data, the impact of T2T-CHM13 in this field remains unexplored. …”
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Biodistribution and dosimetry of the PET radioligand [18F]CHDI-650 in mice for detection of mutant huntingtin aggregates by Jordy Akkermans, Alan Miranda, Jeroen Verhaeghe, Filipe Elvas, Franziska Zajicek, Jonathan Bard, Longbin Liu, Vinod Khetarpal, Robert Doot, Steven Staelens, Daniele Bertoglio

“…Ex vivo and PET-imaging biodistribution of [18F]CHDI-650 showed rapid washout after 30 min in most of the organs with the highest uptake in the gallbladder and urine in mice. Extrapolation of the data to human phantoms with OLINDA showed a total mean in vivo based effective dose of 21.7 μSv/MBq with the highest equivalent organ dose in the urinary bladder wall (4.52 μSv/MBq). …”
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Evaluating ultrastructural preservation quality in banked brain tissue by Macy Garrood, Alicia Keberle, Allison Sowa, William Janssen, Emma Thorn, Claudia De Sanctis, Kurt Farrell, John Crary, Andrew McKenzie

“…However, electron microscopy (EM) data is difficult to interpret when the preservation quality is imperfect, which is common in brain banking and may render it unsuitable for certain research applications. …”
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White matter microstructure links with brain, bodily and genetic attributes in adolescence, mid- and late life by Max Korbmacher, Mario Tranfa, Giuseppe Pontillo, Dennis van der Meer, Meng-Yun Wang, Ole A. Andreassen, Lars T. Westlye, Ivan I. Maximov

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Arthroscopic versus open fixation for medial malleolus fractures improves trauma response and bone healing by Xihong Xie, Danting Ji, Feiqiang Chen, Zejin Lin, Kai Deng, Jinqi Song, Jing Wang

“…Recently, arthroscopy-assisted reduction percutaneous internal fixation (ARPF) demonstrates advantages in minimizing soft tissue damage, improving joint visualization, and enhancing postoperative recovery, however, robust comparative evidence remains sparse on the efficacy of ARPF versus open reduction and internal fixation (ORIF) in treating medial malleolus fractures. …”
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Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response by Rebecca Warfvinge, Linda Geironson Ulfsson, Parashar Dhapola, Fatemeh Safi, Mikael Sommarin, Shamit Soneji, Henrik Hjorth-Hansen, Satu Mustjoki, Johan Richter, Ram Krishna Thakur, Göran Karlsson

“…In addition, we found the ratio of LSC/HSC to be higher in patients with prospective treatment failure compared to optimal responders, at diagnosis as well as following 3 months of TKI therapy. Collectively, this data builds a framework for understanding therapy response and adapting treatment by devising strategies to extinguish or suppress TKI-insensitive LSCs.…”
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Predicting in-hospital mortality in patients with alcoholic cirrhosis complicated by severe acute kidney injury: development and validation of an explainable machine learning model by Meina Sun, Shihui Liu, Jie Min, Jie Min, Lei Zhong, Lei Zhong, Jinyu Zhang, Jinyu Zhang, Zhian Du

“…This study aims to develop and validate machine learning models to predict the mortality risk of this population during hospitalization.MethodsA retrospective analysis was conducted on 856 adult patients with alcoholic cirrhosis complicated by severe AKI, utilizing data from the MIMIC-IV database. Within the dataset, 627 patients from the period 2008–2016 were designated as the training cohort, whereas 229 patients from 2017 to 2019 comprised the temporal external validation cohort. …”
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Improvement of Gasless Laparoscopic Single-Site Lifting and Use in Surgery for Endometrial Carcinoma by Bingbing Zhao, Xinqiu Lu, Xuli Gan, Zhijun Yang, Li Li, Jieqing Zhang

“…We analyzed the differences in procedures in 177 cases of endometrial carcinoma. We collected data on operative time, hemoglobin change, number of lymph nodes removed, postoperative recovery time and postoperative complications for open surgery, multi site laparoscopic surgery, single site laparoscopic surgery and gasless laparoscopic single-site surgery. …”
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Flu‐CED: A comparative transcriptomics database of influenza virus‐infected human and animal models by Yue Wu, Jue Wang, Jing Xue, Zhiguang Xiang, Jianguo Guo, Lingjun Zhan, Qiang Wei, Qi Kong

“…Using integrated and processed transcriptomic data, we established a user‐friendly website for realizing the integration, online retrieval, visualization, and exploration of gene expression of influenza virus infection in different species and the biological functions involved in differential genes. …”
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SmartCityOS: Making Tomorrow Smarter by H. Xu, H. Xu, H. Xu, H. Xu, H. Xu, B. He, B. He, B. He, B. He, C. Zhang, C. Zhang, C. Zhang, C. Zhang, H. Lin, H. Lin, H. Lin, H. Lin, X. Kuai, X. Kuai, X. Kuai, X. Kuai, R. Guo, R. Guo, R. Guo, R. Guo

“…Key technologies, including ubiquitous city perception, digital modeling, spatio-temporal big data fusion and analysis, 3D city visualization, and simulation and digital twin interaction, are emphasized as critical areas of focus. …”
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Temporal, spatial and demographic distributions characteristics of COVID-19 symptom clusters from chinese medicine perspective: a systematic cross-sectional study in China from 201... by Bin Liu, Tian Song, Mingzhi Hu, Zhaoyuan Gong, Qianzi Che, Jing Guo, Lin Chen, Haili Zhang, Huizhi Li, Ning Liang, Jing Wan, Kunfeng Wang, Yanping Wang, Nannan Shi, Luqi Huang

“…Data analysis and visualization were conducted using R software (4.2.0), while the association analysis of symptom clusters was performed using Cytoscape (3.10.2). …”
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Atom Probe Tomography (APT) and Its Application in Ore Deposits by Peng TAO, Shiwen XIE, Tao LONG, Mingzhu MA, Xiaochao CHE

“…From the end of the 20th century to the beginning of the 21st century, the application of laser pulse mode enabled APT to be applied to semiconductors and insulating materials[15-19], and the application of Local Electrode TM Atom Probe (LEAP) improved several key parameters such as the data acquisition rate and mass resolution of APT by several orders of magnitude[20]. …”
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DIAGNOSTICS AND PLANNING OF ORTHODONTIC TREATMENT OF PATIENTS WITH DENTAL ARCH NARROWING USING 3D TECHNOLOGIES by Yu.M. Voliak, Z.R. Ozhohan

“…It is not necessarily to keep numerous stone models to create an archive data of orthodontic patients before and after treatment. …”
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Development and validation of a machine learning-based risk prediction model for stroke-associated pneumonia in older adult hemorrhagic stroke by Yi Cao, Yi Cao, Haipeng Deng, Shaoyun Liu, Xi Zeng, Yangyang Gou, Weiting Zhang, Yixinyuan Li, Hua Yang, Min Peng

“…External validation utilized retrospective data from January–December 2023. After univariate and multivariate regression analyses, four ML models (Logistic Regression, XGBoost, Naive Bayes, and SVM) were constructed. …”
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User Experiences With Digital Future-Self Interventions in the Contexts of Smoking and Physical Inactivity: Mixed Methods Multistudy Exploration by Kristell M Penfornis, Nele Albers, Willem-Paul Brinkman, Mark A Neerincx, Andrea WM Evers, Winifred A Gebhardt, Eline Meijer

“…MethodsSecondary analyses of quantitative and qualitative survey data from 3 studies using digital FSIs as a means to encourage smoking cessation or increase PA were conducted. …”
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Artificial intelligence in endoscopy and colonoscopy: a comprehensive bibliometric analysis of global research trends by Negin Letafatkar, Amr Ali Mohamed Abdelgawwad El-Sehrawy, KDV Prasad, KDV Prasad, Ahmad Alkhayyat, Ahmad Alkhayyat, Ahmad Alkhayyat, Ehsan Amini-Salehi, Maryam Hasanpour, Masoomeh Namdar Taleshani, Mohammad Hashemi, Hadi Alotaibi, Pegah Rashidian, Mohammad-Hossein Keivanlou, Soheil Hassanipour

“…The data were analyzed using VOSviewer, CiteSpace, and R software, focusing on co-authorship, co-citation, and keyword trends.ResultsResearch output on AI in endoscopy and colonoscopy has seen significant growth since 2016, peaking in 2023 with 345 publications. …”
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THE INFLUENCE OF HEART RATE VARIABILITY ON CLINICAL COURSE OF CHRONIC HEART FAILURE AND RENAL FUNCTION IN ATRIAL FIBRILLATION PATIENTS by E. A. Polyanskaya, S. V. Mironova, N. A. Koziolova

“…One of possible mechanisms of the target organs with HRV decline, by our data, might be transformation of collagenolysis towards collagenogenesis in intracellular matrix, according to the dynamics of TIMP-1.…”
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Predicting hypoglycemia risk after gastrointestinal surgery in type 2 diabetes mellitus: a retrospective cohort study by Huilan Yao, Shijin Yuan, Hongying Pan, Sisi Hong, Chen Huang, Linfang Zhao, Hongdi Yuan, Lei Mei, Yinghong Zheng, Xiaolong Liu, Weina Lu

“…ObjectiveTo identify factors influencing hypoglycemia in patients with type 2 diabetes mellitus (T2DM) following gastrointestinal tumor surgery and construct a predictive model for assessing hypoglycemia risk.MethodsWe retrospectively collected data on 1280 patients with T2DM who underwent gastrointestinal tumor surgery and divided them into two groups—one for model building (n = 982) and another for validation (n = 298). …”
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Obliterated cavum septi pellucidi: Clinical significance and role of fetal magnetic resonance by Ilaria Fantasia, Claudia Ciardo, Gabriella Bracalente, Elisa Filippi, Flora Maria Murru, Anita Spezzacatene, Maura Bin, Olivia Mendez Quintero, Elisa Montaguti, Christoph Lees, Katherine Papanikolaou, Gianluigi Pilu, Federico Prefumo, Baskaran Thilaganathan, Tamara Stampalija

“…Where available, postnatal data were collected to obtain information on neurodevelopment. …”
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BibMon: An open source Python package for process monitoring, soft sensing, and fault diagnosis by Afrânio Melo, Tiago S.M. Lemos, Rafael M. Soares, Deris Spina, Nayher Clavijo, Luiz Felipe de O. Campos, Maurício Melo Câmara, Thiago Feital, Thiago K. Anzai, Pedro H. Thompson, Fábio C. Diehl, José Carlos Pinto

“…This paper introduces BibMon, a Python package that provides predictive models for data-driven fault detection and diagnosis, soft sensing, and process condition monitoring. …”
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