Oral Cyclophosphamide for Patients With Metastatic Castration-Resistant Prostate Cancer in a Scenario of Limited Health Care Resources by Diana del Cisne Pineda, Gabriel Berlingieri Polho, Yumi Ricucci Shinkado, Gustavo Alves Contado, Nathalia de Souza Crusoe, Vivian Naomi Horita, Joao Carlos Resende, Jamile Almeida Silva, Guilherme Fialho de Freitas, David Queiroz Muniz, Caio V. Suartz, Leopoldo Alves Ribeiro-Filho, Paulo M. Hoff, José Mauricio Mota

“…PSA50 response was associated with no prior docetaxel use and Eastern Cooperative Oncology Group performance status 0 or 1.CONCLUSIONOral cyclophosphamide is a feasible treatment option for patients with mCRPC, particularly in a scenario of limited health care resources.…”
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Hypoxia-inducible factor 1α is required to establish the larval glycolytic program in Drosophila melanogaster by Yasaman Heidarian, Tess D. Fasteen, Liam Mungcal, Kasun Buddika, Nader H. Mahmoudzadeh, Travis Nemkov, Angelo D'Alessandro, Jason M. Tennessen

“…Notably, our study also reveals that the Sima/HIF1α-dependent gene expression program shares considerable overlap with that observed in dERR mutant, suggesting that Sima/HIF1α and dERR cooperatively regulate embryonic and larval glycolytic gene expression.…”
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Students Perceptions, Satisfactions and Challenges on Problem-Based Learning (PBL): A Survey Study Among Final Year Pharmacy Students by Engku Nuraishah Huda E. Zainudin, Fakhira Damia Khaidir, May Khin Soe, Nurul Asyiqin Yusof, Khairool Azizul Mohammad

“…Most felt comfortable participating in discussions (69%), and nearly all students were satisfied with their group members’ cooperation (95.2%). Although, most findings highlight positive aspects of PBL, this study also identified three major challenges in PBL implementation, namely 1) insufficient time for PBL preparation, 2) lack of teamwork, and 3) difficulty in finding adequate reading materials. …”
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Research hotspots and frontiers in the tumor microenvironment of colorectal cancer: a bibliometric study from 2014 to 2024 by Xinran He, Tingyi Xie, Li Shi, Xuyi Kuang, Lei Li, Xingyu Shang, Bo Fu

“…In addition, keyword and cluster analysis showed that immune checkpoint inhibitors, cancer-associated fibroblasts, macrophage polarization, intestinal microbiota, colorectal cancer liver metastasis, drug resistance, scRNA-seq, etc. may be the research hotspots and trends in this field.ConclusionsColorectal cancer and tumor microenvironment research is in the developmental stage, and strengthening international cooperation can help to drive this field forward. The main components and signaling in TME, CRC immunotherapy, colorectal cancer liver metastasis, and new research techniques are the hot research directions in this domain. …”
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Seasonal resource selection of a grassland bird in a dynamic landscape: Importance of a heterogeneous landscape by Sprih Harsh, Robert C. Lonsinger, Hilary R. Kauth, Andrew J. Gregory

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High Relative Humidity‐Induced Growth of Perovskite Nanowires from Glass toward Single‐Mode Photonic Nanolasers at Sub‐100‐nm Scale by Zhiqiang Wang, Xinkuo Li, Chenduan Chen, Minhan Lou, Jiajia Wu, Kai Gao, Zengling Li, Ke Sun, Zhou Li, Zhu Xiao, Linhan Li, Pan Wang, Sai Bai, Jianrong Qiu, Dezhi Tan

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Surface crystal-orientation-dependent second-order nonlinear optical properties of cubic boron arsenide (c-BAs) by Lipeng Zhu, Yachao Ma, Chuyi Zhou, Tanwen Lai, Aochi Jia, Yipeng Zheng, Kaili Ren, Dongdong Han, Jun Dong, Ze Xue, Yani Ren, Qiyi Zhao, Chuan He, Jiming Zheng

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The right to be forgotten in the context of the Russian-Ukrainian war by S. O. Popova

“…It has been established that companies must cease cooperation with the russia or persons related to it. …”
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Decade-Long Analysis: Unravelling the Spatio-Temporal Dynamics of PM10 Concentrations in Malaysian Borneo by Salwa Naidin, Justin Sentian, Farrah Anis Fazliatul Adnan, Franky Herman, Siti Rahayu Mohd Hashim

“…In order to improve air quality in Malaysian Borneo, it is necessary to take a multifaceted approach encompassing source emissions reduction, inter-country collaboration, region-wide strategies for land and forest management improvement, and reinforced cooperation on pollution monitoring, reporting and reduction efforts.…”
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Interventions to reduce social isolation and loneliness among minority ethnic populations in OECD countries: A scoping review. by Emmanuel Sunday Nwofe, Amirah Akhtar, Sahdia Parveen, Karen Windle

“…People from minority ethnic backgrounds living in Organisation for Economic Cooperation and Development (OECD) member states may be particularly vulnerable to experiencing SIL. …”
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Three effective cases of transcatheter arterial embolization after atezolizumab and bevacizumab treatment for hepatocellular carcinoma: a case report by Koji Rinka, Kiyohide Kioka, Yuga Amano, Takashi Nakai, Yasuko Kawasaki, Norifumi Kawada

“…Abstract Background The Barcelona Clinic Liver Cancer staging system classifies hepatocellular carcinoma on the basis of tumor characteristics, liver function, and Eastern Cooperative Oncology Group performance status. Hepatocellular carcinoma is divided into five stages, and the treatment options for intermediate-stage hepatocellular carcinoma have evolved in recent years. …”
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Assessment of Physicochemical Characteristics of Produced Water from Terminals of Some Oil Industry Facilities in Nigeria by CC Obunwo, C Chukwudi

“…The samples were preserved accordingly and transported to the laboratory in ice - packed coolers. The levels of the physico-chemical properties of produced water in the two locations, showed that mean temperature, pH, TDS, TSS, salinity and turbidity levels were: 24.40± 0.35oC – 25.50 ± 0.35oC; 7.49 ± 0.28 – 7.89 ± 0.30; 8428 ±2332mg/l – 9205 ± 2100mg/l; 8.50 ± 3.40mg/l – 14.30 ± 5.10mg/l; 6108± 1250mg/l – 7422 ± 2280mg/l and 16.00 ± 5.00 NTU – 37.00 ± 9.60 NTU respectively. …”
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Gendered impact of COVID-19 containment measures on unpaid care work and mental health in Europe: a scoping review protocol by Kathleen Pöge, Hande Gencer, Regina Brunnett, Maria A Marchwacka, Petra Rattay, Tobias Staiger, Hürrem Tezcan-Güntekin

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Multiple Dimensions Define Thresholds for Population Resilience of the Eastern Oyster, Crassostrea virginica by Megan K. La Peyre, Hongqing Wang, Shaye E. Sable, Wei Wu, Bin Li, Devin Comba, Carlos Perez, Melanie Bates, Lauren M. Swam

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Shade signals activate distinct molecular mechanisms that induce dormancy and inhibit flowering in vegetative axillary buds of sorghum by Tesfamichael H. Kebrom

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Aplikasi Pencari Kerja Sampingan Berbasis Framework Flutter by Desy Intan Permatasari, M. Udin Harun Al Rasyid, Yuliarta Rizki Nusantoko

“…This problem prompted the author to create a side job seeker application that brings side job providers and side job seekers together in one digital platform in order to encourage the creation of economic mutual cooperation in people's lives. The application that will be made by the author combines the features of the Grab/Go-JEK application with the E-commerce application. …”
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Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers by Pin Deng, Hongshuo Shi, Xuyue Pan, Huan Liang, Shulong Wang, Junde Wu, Wei Zhang, Fasen Huang, Xiaojie Sun, Hanjie Zhu, Zhaojun Chen

“…The University of Washington had the greatest number of publications within this time period (n=103), and it had the most cooperative units and was in the core position in all research institutions, followed by the University of Manchester (n=94) and the University of Miami (n=92). …”
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The People's Commissariat of Foreign Affairs (NKID) of the USSR in the City of Kuibyshev (1941-1943) by S. I. Chernyavsky

“…Among other tasks were the search for allies, establishing effective military, economic and political cooperation with them, counteracting the expansion of the Nazi coalition at the expense of Sweden and Turkey, and conducting an extremely balanced policy in the Far East in order to avoid a military clash with Japan.Due to the deterioration of the military situation on the Western Front and the imminence of the capture of Moscow, on October 16, 1941, the main staff of the People's Commissariat for Foreign Affairs, headed by its Deputy Chairman A. …”
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Analysis of Adverse Pregnancy Outcomes of Pregnant Women with Syphilis and Maternal-Infant Serological Association in Changzhou, China, 2015–2019 by Chaorong Bian, Zhiqiang Qin, Jieying Zhang, Mengtao Sun, Manman Gu, Kejin Chen

“…Pregnant women with syphilis should actively cooperate with their doctors in the standardized treatment of pregnancy, and doctors should also pay more attention to pregnant women with syphilis whose initial titers are greater than 1 : 8. …”
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Simulation of Flow Around a Finite Rectangular Prism: Influence of Mesh, Model, and Subgrid Length Scale by Xutong Zhang, Maxime Savoie, Mark K. Quinn, Ben Parslew, Alistair Revell

“…Ten turbulence modelling and simulation approaches, including both ‘scale-modelling’ Reynolds-Averaged Navier–Stokes (RANS) models and ‘scale-resolving’ Delayed Detached Eddy Simulation (DDES), were tested across six different mesh resolutions. A case with sharp corners allows the location of the flow separation to be fixed, which facilitates a focus on the separated flow region and, in this instance, the three-dimensional interaction of three such regions. …”
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