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The Crohn’s Disease Activity Index, Its Derivatives and the Inflammatory Bowel Disease Questionnaire: A Review of Instruments to Assess in Crohn’s Disease
Published 1999-01-01“…The Crohn’s Disease Activity Index (CDAI) has been used to measure Crohn’s activity for over a quarter of a century. …”
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Assessment of the usefulness of imaging studies and biomarkers in the activity of Crohn’s disease
Published 2020-03-01Subjects: “…crohn’s disease activity index…”
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3
Systemic Immune-Inflammation Index: A Promising, Non-Invasive Biomarker for Crohn’s Disease Activity and Severity Assessment
Published 2025-01-01“…We aim to evaluate the systemic immune-inflammation index (SII) as a prognostic biomarker in CD and its utility in predicting disease activity and severity.Patients and Methods: This retrospective study analyzed CD patients using the Harvey-Bradshaw index (HBI) for disease stratification and the Simple Endoscopic Score for Crohn’s Disease (SES-CD) for post-treatment evaluation. …”
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4
Combination Ciprofloxacin and Metronidazole for Active Crohn’s Disease
Published 1998-01-01“…Recent experimental evidence underscores the contribution of intestinal bacteria to the inflammatory process of Crohn's disease. This open study examined the efficacy and safety of combination ciprofloxacin and metronidazole for patients with active Crohn's disease of the ileum and/or colon. …”
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Impact of Disease Activity on the Quality of Life of Crohn’s Disease Patients
Published 1996-01-01“…The 10 patients with the largest decrease in disease activity over time (mean decrease of 43.54 points using the Dutch Activity Index) had significant improvement in quality of life on the bowel and systemic subscales. …”
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6
Oral 5-Aminosalicyclic Acid Versus 6-Methylprednisolone in Active Crohn's Disease
Published 1990-01-01“…The Crohn's disease activity index (CDAI) and the van Hees index were not significantly different in both treatment groups at the entrance examination (median CDAI 232 in the 5-ASA group and 220 in the methylprednisolone group). …”
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Open Trial of Cyclosporine in Patients with Severe Active Crohn's Disease Refractory to Conventional Therapy
Published 1988-01-01“…T he remaining 10 patients all improved within four weeks as measured by three different clinical indices: Crohn's Disease Activity Index, Simple Index of Crohn's Disease Activity and Mean Score of Therapeutic Goals (MSTG). …”
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Role of Cyclosporine in Crohn's Disease
Published 1990-01-01“…A prospective, placebo controlled, international trial of cyclosporine A in patients with steroid-resistant Crohn's disease was recently published. All patients in this study had active Crohn's disease (Crohn's disease activity index greater than 150). …”
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A review of magnetic resonance enterography based Crohn’s disease activity indices in paediatric patients
Published 2022-03-01“…Following a PubMed database literature search (January 2008 – November 2021), out of 316 research papers, 10 original papers about MRE-CD activity indices were included in the analysis. Four MRE-based scoring systems were discussed: Magnetic Resonance Index of Activity (MARIA), the Crohn’s Disease Magnetic Resonance Imaging Index (CDMI), the Magnetic Resonance Enterography Global Score (MEGS) and the Visual Analogue Scale (VAS). …”
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Interrelationships of the Intestinal Microbiome, Trimethylamine N-Oxide and Lipopolysaccharide-Binding Protein with Crohn’s Disease Activity
Published 2024-12-01“…Crohn’s disease (CD) is a multifactorial inflammatory bowel disease whose pathogenetic mechanisms are a field of ongoing study. …”
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Thiopurines in the Management of Crohn’s Disease: Safety and Efficacy Profile in Patients with Normal TPMT Activity—A Retrospective Study
Published 2016-01-01“…Thiopurines are used in the treatment of Crohn’s disease (CD) and thiopurine S-methyltransferase (TPMT) activity can guide thiopurine dosing to avoid adverse events. …”
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Assessment of Disease Activity in Small Bowel Crohn’s Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score
Published 2015-01-01“…A significant correlation p<0.0001 was observed between MRIA and mMRIA scores and between both MR indexes and SES p<0.0001. Conclusions. mMRIA was comparable to MRIA in the evaluation of disease activity in Crohn’s disease.…”
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13
Alterations of Serum Bile Acid Profile in Patients with Crohn’s Disease
Published 2022-01-01“…The correlation analysis showed that the SBA, DCA, GDCA levels, and DCA/(DCA + CA) ratio had an inverse relationship with Crohn’s Disease Activity Index. Conclusion. The BA profile exhibits significant alterations in CD patients. …”
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Long-Term Clinical Behavior of Jejunoileal Involvement in Crohn’s Disease
Published 2005-01-01“…New treatments are required, possibly defined on the basis of their effectiveness in reducing the severity and extent of intestinal disease, rather than more conventional statistically driven reductions in disease activity indexes.…”
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Difficulties the Conservative Treatment of Crohn’s Disease Complicated by Autoimmune Hemophilia A
Published 2020-01-01“…To present a clinical case describing the management of a patient with Crohn’s disease complicated by recurrent intestinal bleeding and autoimmune hemophilia A.General provisions: A 21-year-old patient was admitted to St. …”
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A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecie...
Published 2025-03-01“…Secondary objectives of immunogenicity were assessed by ELISpot (enzyme-linked immunosorbent spot) and clinical response by Crohn’s Disease Activity Index (CDAI) and Simple Endoscopic Score for Crohn’s Disease (SES-CD). …”
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Exclusive Enteral Nutrition versus Infliximab in Inducing Therapy of Pediatric Crohn’s Disease
Published 2017-01-01“…To compare the effectiveness of exclusive enteral nutrition (EEN) and infliximab (IFX) therapy in pediatric Crohn’s disease (CD). Methods. In a prospective study of children initiating EEN or infliximab therapy for CD, we compared clinical outcomes using the pediatric Crohn’s disease activity index (PCDAI), growth improvement, endoscopic mucosal healing, and adverse effects. …”
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Infliximab Combined with Enteral Nutrition for Managing Crohn’s Disease Complicated with Intestinal Fistulas
Published 2016-01-01“…We evaluated the laboratory indexes, Crohn’s disease activity index (CDAI), Crohn’s disease simplified endoscopic score (SES-CD), and healing of fistula in the two groups before treatment, at 14 weeks, and at 30 weeks, respectively. …”
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Leucine-rich alpha-2 glycoprotein in combination with C-reactive protein for predicting endoscopic activity in Crohn’s disease: a single-centre, cross-sectional study
Published 2025-12-01“…In patients undergoing ileocolonoscopy or balloon-assisted enteroscopy within 60 days before or after LRG measurement, endoscopic activity was evaluated with the simple endoscopic score for Crohn’s disease (SES-CD). …”
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Adalimumab for endoscopic and histopathological mucosal healing in paediatric patients with moderate to severe Crohn’s disease
Published 2016-12-01“…Colonoscopy and gastroscopy with sample collection were performed in all patients before and after induction treatment with ADA. Clinical activity of the disease was assessed using the Paediatric Crohn’s Disease Activity Index (PCDAI), and the endoscopic activity was scored using the Simple Endoscopic Score (SES-CD). …”
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