Gastroduodenal form of Crohn's disease by I. V. Mayev, D. N. Andreev, Yu. A. Kucheryavy

“…To highlight modern aspects of clinical presentation, diagnostics and treatment of gastroduodenal variant of Crohn's disease (GDCD).Key points. Gastroduodenal involvement at CD is a rare clinical variant of disease and develops in less than 5,5% of cases. …”
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Features of Crohn's Disease Depending on the Age of Disease Onset by E. G. Ganich, O. B. Shchukina

“…Aim: to evaluate the characteristics of Crohn's disea depending on the age of the disease onset in patients observed in a specialized City Center for Inflammatory Bowel Diseases Diagnosis and Treatment.Materials and methods. …”
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Gut microbiota dysfunction in Crohn’s disease by Sylvie Buffet-Bataillon, Sylvie Buffet-Bataillon, Gabriela Durão, Isabelle Le Huërou-Luron, Olivier Rué, Olivier Rué, Yann Le Cunff, Vincent Cattoir, Guillaume Bouguen

“…IntroductionCrohn’s disease (CD) results from alterations in the gut microbiota and the immune system. …”
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Significance of immune factors in Crohn's disease development by D. S. Stavtsev, T. A. Astrelina, O. V. Knyazev, T. V. Pukhlikova

“…To analyze modern approach to pathogenesis of Crohn's diseases (CD), to determine effect of individual immunogenetic factors on development and progression of disease, in particular, in relation to HLA profile.Summary. …”
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The effect of maintenance therapy on Crohn’s disease clinical outcomes by O. B. Schukina, E. A. Kondrashina, A. M. Kharitidis, Ye. G. Vepreva, A. G. Kharitonov, A. Yu. Baranovsky

“…To study the effect of maintenance therapy on clinical outcomes of Crohn’s disease (CD) in patients with inflammatory and complicated forms. …”
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Prominence of Microbiota to Predict Fibrous Stenosis in Crohn’s Disease by Yang X, Pan Y, Gao CP, Li H, Zhang YH, Huang CL, Cao L, Xiao SY, Zhou Z

“…Xue Yang,* Yan Pan,* Cai-Ping Gao, Hang Li, Ying-Hui Zhang, Chun-Li Huang, Lu Cao, Shi-Yu Xiao, Zhou Zhou Department of Gastroenterology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhou Zhou; Shi-Yu Xiao, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China, Email doublezhouu2006@163.com; xiaoshiyu57@163.comPurpose: Intestinal fibrous stenosis due to Crohn’s disease (CD) is highly prevalent. Although several clinical risk factors for fibrous stenosis have been identified, such as perianal fistulizing disease, small bowel disease location, and deep mucosal ulceration, predicting fibrous stenosis remains challenging. …”
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Disutility Study for Adult Patients with Moderate to Severe Crohn’s Disease by Melany Worbes-Cerezo, Beenish Nafees, Andrew Lloyd, Katy Gallop, Imran Ladha, Cicely Kerr

“…**Background:** Crohn’s disease (CD) treatments and associated adverse events (AEs) can be burdensome for patients. …”
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Multi-detector computer tomography as effective method for Crohn's disease diagnostics by A. A. Tikhonov, A. V. Gorinov, I. V. Zarodnyuk, I. L. Khalif, Ye. S. Korolevsky

“…Improvement of diagnostics and efficacy of radiological methods of investigation by technique computer-tomography (CT) enterography at inflammatory bowel diseases.Material and methods. Original investigation was based on the data of comprehensive clinical and instrumental investigation of 111 patients with suspected Crohn's disease (CD). …”
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Altered functional network topology properties to detect anxiety and depression caused by Crohn’s disease and disease severity by Jiaxing Yang, Kechen Yue, Jingwen Sun, Changjie Pan, Xintong Wu, Yongjun Cheng, Xiaomeng Wu, Haifeng Shi

“…Objective: Here we investigated changes in topological properties of functional brain networks among individuals with Crohn’s disease (CD) and to determine whether these changes are related to CD severity, as well as CD-associated anxiety and depression, which are regulated by the brain–gut axis mechanism. …”
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Prevalence and predictors of severe Crohn’s disease at a tertiary hospital in South Africa by C Gounden, V Naidoo, Y Moodley

“…Methods This was a retrospective chart review of patients with Crohn's disease (CD) attending the Gastroenterology Unit at a tertiary hospital in Durban, South Africa. …”
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Investigating the Activity Status of Inflammatory Bowel Disease and its Related Factors: A Study Protocol by Mehrnaz Asgharnezhad, Ehsan Amini-Salehi, Niloofar Faraji, Soheil Hassanipour, Saman Maroufizadeh, Adele Isanazar, Marjan Mahdavi-Roshan, Zahra Hedayatzadeh, Farahnaz Joukar, Fariborz Mansour Ghanaei

Subjects: “…crohn’s disease (cd)…”
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Controversies in the management of anti-TNF therapy in patients with Crohn’s disease: a Delphi consensus by Ignacio Marin-Jimenez, Guillermo Bastida, Daniel Carpio, Fernando Muñoz, Yago González-Lama, Elena Ricart, Daniel Ceballos, Daniel Ginard, Luis Menchen

“…Background Despite research, there are still controversial areas in the management of Crohn’s disease (CD).Objective To establish practical recommendations on using anti-tumour necrosis factor (TNF) drugs in patients with moderate-to-severe CD.Methods Clinical controversies in the management of CD using anti-TNF therapies were identified. …”
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Assessment of Serum Dynamic Thiol/Disulfide Homeostasis and Oxidative/Nitrosative Stress in Patients with Crohn’s Disease by Ancel Aysun Bağdaş, Sezgin Barutçu, Ahmet Saracaloğlu, Abdullah Tuncay Demiryürek

“…Background/Aims: Crohn’s disease (CD) is a major subtype of chronic relapsing inflammatory gastrointestinal disorders. …”
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Epidemiology and Treatment Patterns of Fistulizing Crohn’s Disease in a Large, Real-World Australasian Cohort by Jack McNamara, William Wilson, Joseph L. Pipicella, Simon Ghaly, Jakob Begun, Ian C. Lawrance, Richard Gearry, Jane M. Andrews, Susan J. Connor

“…Background and Aims: Fistulizing Crohn’s Disease (fCD) affects up to 50% of people with Crohn’s Disease over their lifetime. …”
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Role of autophagy defects and significance of adherent-invasive <i>Escherichia coli</i> in Crohn's disease development by I. V. Mayev, D. N. Andreev, D. V. Rakitina, Yu. P. Baykova

“…To present new data on a role of molecular genetic disorders of innate immunity at Crohn's disease (CD), and to demonstrate the role of adherent-invasive Escherichia coli (AIEC) as the microorganisms potentially involved in CD development.Summary. …”
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Comparative analysis of enteroscopy, computed tomography enterography, and intestinal ultrasound for the evaluation of small bowel Crohn’s disease by Bo Peng, Zhongcheng Liu, Zicheng Huang, Huixian Lin, Zhiyue Wang, Qin Guo

“…Background: The comparable evaluation of computed tomography enterography (CTE), enteroscopy, and intestinal ultrasound in small bowel Crohn’s disease (CD) is imprecise. Objectives: The purpose of this study was to analyze the findings of enteroscopy, CTE, and intestinal ultrasound to determine the advantages and disadvantages of each method for the evaluation of small bowel CD. …”
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Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease by D. A. Kuznetsova, M. V. Merzlyakov, G. V. Vavin, A. S. Razumov, V. L. Emanue

“…To discuss features of prevalence and the clinicodiagnostic role of R702W, G908R and 3020insC NOD2 gene polymorphisms associated to Crohn's disease (CD) in various populations and regions of the world. …”
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Lymphocyte levels in Crohn’s disease patients in clinical remission are significantly lower than those in healthy people by Asi He, Tulan Hu, Linzhen Li

“…Patients and methods A total of 94 Crohn’s disease (CD) and 20 ulcerative colitis (UC) patients were included in this study. …”
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Sources of Bias in Common Diagnosis of Chronic Inflammatory Bowel Diseases by O. A. Svatkova, A. A. Sheptulin

“…We continuously sampled 80 CIBD histories (44 of ulcerative colitis, UC, and 36 of Crohn’s disease, CD) to estimate the time and nature of first complaints, primary diagnosis, time lapse between the first physician visit and diagnosis and reasons for a late diagnosis.Results. …”
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Analysis of Healthcare Resource Utilization and Costs after the Initiation of Biologic Treatment in Patients with Ulcerative Colitis and Crohn’s Disease by Sue Perera, Shibing Yang, Marni Stott-Miller, Joanne Brady

“…**Background:** This retrospective cohort study aimed to describe and quantify healthcare resource utilization and costs for patients with ulcerative colitis (UC) and Crohn’s disease (CD) following initiation of biologic therapy. …”
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