Monitoring the Microcirculation in Critical Conditions: Possibilities and Limitations by T. O. Tokmakova, S. Yu. Permyakova, A. V. Kiseleva, D. L. Shukevich, E. V. Grigoryev

“…The paper provides an analytical review of the references on the role of microcirculatory disorders in the development of critical conditions, the significance of circulatory monitoring, specifically, to make a presumptive prognosis of multiple organ dysfunction. …”
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Management of Atrial Fibrillation in Critically Ill Patients by Mattia Arrigo, Dominique Bettex, Alain Rudiger

“…This paper provides a reappraisal of the management of AF with a special focus on critically ill patients with haemodynamic instability. …”
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Viscoelastic Haemostatic Assays in Cardiovascular Critical Care by Aniket S Rali, Ahmed M Salem, Melat Gebre, Taylor M Garies, Siva Taduru, Arthur W Bracey

“…The initiation and management of anticoagulation is a fundamental practice for a wide variety of indications in cardiovascular critical care, including the management of patients with acute MI, stroke prevention in patients with AF or mechanical valves, as well as the prevention of device thrombosis and thromboembolic events with the use of mechanical circulatory support and ventricular assist devices. …”
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Aspects of cytomegalovirus reactivation in critically ill patients by V. V. Gorbachev, T. I. Dmitrachenko, V. M. Semenov, S. K. Egorov

“…The study included 118 critically ill patients with severe bacterial and viral-bacterial infections accompanied by multiple organ dysfunction. …”
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Oxidative Stress in Critical Conditions and its Correction by N. A. Osipova, N. V. Edeleva, R. I. Yakubovskaya, Ye. R. Nemtsova, V. I. Chissov

“…Severe postoperative complications and critical conditions caused by profuse hemorrhage, pulmonary thromboembolism, anaphylactic shock in response to drugs, as well as circulatory arrest, pyoseptic processes are accompanied by significant activation of free radical lipid oxidation along with progressive depletion of the antioxidative defense system, i. e. the development of oxidative stress underlying the development of acute multiple organ dysfunctions (MOD) of posthypoxic or toxemic genesis, and they require special treatment policy. …”
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Plasma proteomic profiles correlate with organ dysfunction in COVID‐19 ARDS by Moemen Eltobgy, Brett Klamer, Daniela Farkas, James D. Londino, Joshua A. Englert, Jeffrey C. Horowitz, Rama K. Mallampalli, Guy Brock, Joseph S. Bednash

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Prevalence of erectile dysfunction as long-COVID symptom in hospitalized Japanese patients by Hideaki Kato, Nao Ichihara, Hiroki Saito, Shigeki Fujitani, Kohei Ota, Yuji Takahashi, Toshiyuki Harada, Takeshi Hattori, Mitsuru Komeya, Mariko Hosozawa, Yoko Muto, Miyuki Hori, Arisa Iba, Hiroyasu Iso, Hiroyasu Iso, The COVID-19 Recovery Study II Group

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Patterns of left and right ventricular dysfunction and their clinical outcomes in septic patients by Hongmin Zhang, Beijun Gao, Ye Liu, Qing Zhang, Xiaoting Wang

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Developmental parameters and physical fitness in preschool children with Minor Neurological Dysfunction by Halil Alkan, Akmer Mutlu, Göknur Haliloğlu

“…The preschool years constitute a critical period during which significant changes are experienced in the acquisition of locomotor skills due to maturation of the nervous system. …”
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GABA dysfunction in schizophrenia: The GABAA receptor as a potential therapeutic target by Brandon L.M. Crotchett, Seth D. Reighard, Henry A. Nasrallah

“…Growing evidence supports a broader neurobiological framework in which cortical excitation-inhibition (E/I) imbalance acts as an upstream contributor to dopaminergic dysregulation in schizophrenia, with the neurotransmitters gamma-aminobutyric acid (GABA) and glutamate playing a critical role in this homeostasis. Herein, we summarize such evidence, including preclinical findings from animal models of schizophrenia that support the role of GABAergic dysfunction in disease pathophysiology and validate the GABAA receptor as a promising therapeutic target. …”
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Urinary tract microbiota in patients with multiple sclerosis and neurogenic pelvic dysfunction by E. I. Luzanova, M. I. Karpova, O. S. Abramovskikh, E. A. Chetvernina, S. V. Kupriyanov

“…Therefore, the issue of infection prevention in MS is critical. Effective personalized prevention of urogenital infections is possible with a clear understanding of the microbiota composition. …”
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Research progress on the role of oxidative stress in the development of diabetic bladder dysfunction by WANG Liyang, XUE Wei

“…Recent studies have highlighted the critical role of oxidative stress in the development and progression of DBD. …”
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Dysfunctional K⁺ Homeostasis as a Driver for Brain Inflammation by Nagihan Ozsoy, Mark L. Dallas

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Circadian clock dysfunction in Parkinson’s disease: mechanisms, consequences, and therapeutic strategy by Müge Yalçin, Valentina Grande, Tiago Fleming Outeiro, Angela Relόgio

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Research progress of mitochondrial dysfunction induced pyroptosis in acute lung injury by Luhan Yang, Qingyi Ren, Yaohui Wang, Yucheng Zheng, Fei Du, Fang Wang, Jie Zhou, Linxi Gui, Shengdong Chen, Xiurui Chen, Wanting Zhang, Yuhong Sun, Xiaolin Zhong, Hao Liu, Xian Jiang, Zhuo Zhang

“…Abstract Acute lung injury (ALI) is a common critical respiratory disease in clinical practice, especially in the ICU, with a high mortality rate. …”
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Social Cognition Dysfunctions in Neurodegenerative Diseases: Neuroanatomical Correlates and Clinical Implications by Foteini Christidi, Raffaella Migliaccio, Hernando Santamaría-García, Gabriella Santangelo, Francesca Trojsi

“…Specifically, in some NDs these deficits may represent core diagnostic criteria, such as for behavioral variant frontotemporal dementia (bvFTD), or may emerge during the disease course as critical aspects, such as for Parkinson’s and Alzheimer’s diseases. …”
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The status of studies on the mechanism of microcirculatory dysfunction in the process of diabetic kidney injury by Zeng Wu, Yu Gao, Chun-yue Zuo, Xiao-rong Wang, Xiao-han Chen, Xiao-hong Zhou, Wei-juan Gao

“…Moreover, persistent hyperglycemia is also a critical factor causing renal microcirculatory dysfunction. …”
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Prevalence and contributing factors of executive cognitive dysfunction symptoms in university students. by Mohammad Fraiwan, Fidaa Almomani, Hanan Hammouri

“…Conversely, regular sports participation and exercise were linked to lower dysfunction scores (p = 0.0327), suggesting a protective effect. …”
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Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target by Chiara Piazzai, Alessio Petrone, Andrea Stefanini, Flavio D’Ascenzi, Iacopo Olivotto, Iacopo Olivotto, Matteo Cameli

“…Early detection through comprehensive multimodal imaging and timely therapeutic intervention can potentially mitigate these risks, making atrial myopathy both a critical prognostic factor and a promising therapeutic target.…”
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Sexual dysfunction following low-dose-rate brachytherapy for prostate cancer by A. D. Anosov, M. E. Efremov, V. L. Medvedev, M. I. Kogan

“…Despite the advantages associated with LDRT, evidence has accumulated regarding the potential complications accompanying this treatment approach, including sexual dysfunction and erectile dysfunction. Sexual satisfaction constitutes a critical concern for men undergoing PCa treatment. …”
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