Clinical Utility of Serum Lactate and Albumin in Predicting Mortality in Patients with Sepsis Admitted to the Intensive Care Unit: A Prospective Cohort Study by Benjamin Isac John, AS Sathiqali, Rohith George, B Mukhtarahmed

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Mitochondrial Dysfunction Contributes to Sustained Muscle Loss After Cardiac Surgery: A Prospective Observational Study by Ashley N. Thomas, Antonis Kalakoutas, Martin Yates, John Yap, Julie Sanders, Paul Kemp, Mark J. D. Griffiths

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Utility of the neonatal and pediatric sequential organ failure assessment scores in critically ill term neonates by Lara Nicolas, James L. Wynn, Diomel de la Cruz

“…BackgroundThe pediatric sequential organ failure assessment (pSOFA) and neonatal SOFA (nSOFA) scores are used to assess organ dysfunction and predict mortality in critically ill children and neonates. …”
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The Comparison of scoring systems: SOFA, APACHE-II, LODS, MODS, and SAPS-II in critically ill elderly sepsis patients by Bilal Tekin, Jehat Kiliç, Gürhan Taşkin, İhsan Solmaz, Onur Tezel, Bilgin Bahadır Başgöz

“…We evaluated the predictive value of frequently used scoring systems on mortality in critically ill elderly sepsis patients. Methodology: In this single-center, observational, prospective study, critically ill elderly sepsis patients were evaluated. …”
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The Prevalence of Chronic Diseases in Children who Have Undergone Critical Periods with A Different Severity of Organ Dysfunction in the Neonatal Period: A Retrospective Cohort Study by Elena N. Serebryakova, Leyla S. Namazova-Baranova, Irina A. Belyaeva, Dmitrii K. Volosnikov

“…It is assumed that the severity of the multiple organ dysfunctions syndrome (MODS) in children who have experienced critical conditions in the neonatal period may influence the prevalence of chronic diseases in the preschool age. …”
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Multi-center randomized superiority clinical trial in the early phase of mechanically ventilated patients to preserve diaphragm thickness using non-invasive magnetic phrenic nerve... by Annia F. Schreiber, Carles Subirà, Michael Sklar, Marlene Santos, Matthew Ko, Alessandro Panelli, Stefan J. Schaller, Danny Theodore, Daniel D. Rowley, David Watson, Pramod Bonde, Elias N. Baedorf Kassis, Daniel S. Talmor, Marco Ranieri, Ewan C. Goligher, Arthur Slutsky, Laurent J. Brochard

Subjects: “…Ventilator-induced diaphragm dysfunction…”
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The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19 by Britta Westhus, Patrick Thon, Lars Palmowski, Katharina Rump, Björn Koos, Frederik Wiebel, Birte Dyck, Martin Eisenacher, Martin Eisenacher, Barbara Sitek, Barbara Sitek, Stephanie Pfaender, Stephanie Pfaender, Nina Babel, Moritz Anft, Christian Putensen, Stefan Felix Ehrentraut, Christina Weisheit, Alexander Zarbock, Thilo von Groote, Andrea Witowski, Matthias Unterberg, Hartmuth Nowak, Hartmuth Nowak, Alexander Wolf, Lars Bergmann, Michael Adamzik, Dominik Ziehe, Tim Rahmel

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Clinical utility of diaphragmatic ultrasound for mechanical ventilator liberation in adults: a systematic review and meta-analysis by Naonori Tashiro, Hiroki Nishiwaki, Takashi Ikeda, William M. M. Levack, Hisashi Noma, Noyuri Yamaji, Erika Ota, Takeshi Hasegawa

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The Incidence of Acute Respiratory Infections in Children who Have Undergone Critical Conditions in the Neonatal Period, Depending on the Severity оf Organ Dysfunction.... by Elena N. Serebryakova, Irina A. Belyaeva, Dmitrii K. Volosnikov

“…Background: It is assumed that the severity of the multiple organ dysfunctions syndrome (MODS) in children who have experienced critical conditions in the neonatal period is a risk factor for the development of acute respiratory infections (ARI). …”
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Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome by Cao Z, Zhou Q, An J, Guo X, Jia X, Qiu Y

“…This review synthesizes current evidence on glycolysis’s critical role in PCOS pathophysiology, its influence on follicular energetics and oocyte quality, and highlights metabolic targets for future therapies, offering a foundation for novel mechanism-driven interventions in PCOS management.Keywords: polycystic ovary syndrome, glycolysis, metabolic dysfunction, insulin resistance, granulosa cells, oxidative stress, metabolic therapy…”
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SOX17 is a Critical Factor in Maintaining Endothelial Function in Pulmonary Hypertension by an Exosome‐Mediated Autocrine Manner by Xiaozhou Zou, Ting Liu, Zhongjie Huang, Wei Zhou, Mengnan Yuan, Hongying Zhao, Zongfu Pan, Pengcheng Chen, Yanfei Shao, Xiaoping Hu, Su Zhang, Shuilian Zheng, Yiwen Zhang, Ping Huang

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European Society of Intensive Care Medicine и Society of Critical Care Medicine: 6 key provisions for management of sepsis patients. Where do we go next? by V. A. Rudnov, V. A. Bagin, M. N. Аstafieva

“…The objective: to analyze the validity of recommendations of the special research committee of the European Society of Intensive Care Medicine (ESICM) and Society of Critical Care Medicine (SCCM) concerning the most important provisions for the management of patients with sepsis and septic shock identifying predictors of long-term need for medical care and lethality.Subjects and methods. …”
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The Predisposition, Infection, Response and Organ Dysfunction (PIRO) Scoring System in Predicting Organ Dysfunction and Mortality in Septic Patients by Ahmed Atef, Mohamed Abo Hamela, Mahmoud Khaled, Khaled Hussein

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Sonographic diaphragmatic parameters as a predictor of weaning failure in critically ill patients in need of invasive mechanical ventilation: a prospective observational cohort stu... by Prathmesh G. Kumbhar, Manvinder Tejpal, Sunaina T. Karna, Pooja Singh, Saurabh Saigal, Vaishali Waindeskar

“… Weaning from invasive mechanical ventilation is difficult in critically ill patients, with diaphragmatic dysfunction being a key factor. …”
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NK cell dysfunction in antiphospholipid syndrome by Anush Martirosyan, Eva Kriegova, Gayane Manukyan, Gayane Manukyan

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Risk analysis of the association between EASIX and all-cause mortality in critical ill patients with atrial fibrillation: a retrospective study from MIMIC-IV database by Yu Xia, Anfeng Liang, Mei Wang, Jianlin Zhang

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Apoptosis in Critical Conditions by A. M. Golubev, E. Yu. Moskaleva, S. E. Severin, T. P. Vesnyanko, A. N. Kouzovlev, A. S. Alkadarsky, G. G. Poroshenko

“…Based on a literature update, the authors analyze the role of apoptosis in the pathogenesis of various critical conditions: acute lung lesion (neutrophilic and epithelial hypotheses), sepsis, myocardial infarction, and ischemic stroke (apoptosis of tubular epithelial cells), hepatic dysfunction in sepsis, myopathies in critical conditions. …”
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Myocardial Dysfunction in Sepsis: A Large, Unsolved Puzzle by Constantino Jose Fernandes Jr., Murillo Santucci Cesar de Assuncao

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Postoperative Pulmonary Dysfunction and Mechanical Ventilation in Cardiac Surgery by Rafael Badenes, Angels Lozano, F. Javier Belda

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Failed Weaning from Mechanical Ventilation and Cardiac Dysfunction by Jahan Porhomayon, Peter Papadakos, Nader D. Nader

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