Unravelling the complex interplay of cuproptosis, lncRNAs, and immune infiltration in Alzheimer’s disease: a step towards novel therapeutic targets by Yi Zeng, Siqi Qian, Yuan Cao, Wenbiao Xiao

“…The RF model pinpointed the five most critical CRGs, which were validated in the test set with an AUC of 0.90. …”
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Building boundary-crossers in clinical-translational research: An exploratory study of a novel communication intervention by Carrie Cameron, Irene Rull-Garcia, Laura G. Meyer, Jose-Armando Fernandez-Guerrero, Erin K. Dahlstrom, Christine Bell, Christine Pribbenow

“…Data were organized, individually coded, and then iteratively and collectively into pre-defined and emergent themes. …”
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Characterizing adaptation responses to drought risk of livestock farmers in the Spanish dehesa agroforestry system by Nikoletta Ropero Szymañska, Nuria Hernández-Mora, Lucia De Stefano

“…Qualitative data was collected through interviews, focus groups and workshops, and coded and analyzed through deductive content analysis and complementary statistical correlation and multicriteria analysis. …”
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LncRNA GTF3C1 promotes diabetic corneal wound healing by regulating GABARAP and PTEN to augment autophagy by Danling Liao, Wenqu Chen, Yuyang Deng, Shijia Wei, Li Wang, Jianzhang Hu

“…This study aims to explore the role of long non-coding RNAs (lncRNAs) in modulating autophagy during diabetic pathogenesis, focusing on lncRNA general transcription factor IIIC subunit 1 (GTF3C1) and its potential as a therapeutic target for diabetic corneal neuropathy (DCN). …”
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A transcriptomic analysis of Echinococcus granulosus larval stages: implications for parasite biology and host adaptation. by John Parkinson, James D Wasmuth, Gustavo Salinas, Cristiano V Bizarro, Chris Sanford, Matthew Berriman, Henrique B Ferreira, Arnaldo Zaha, Mark L Blaxter, Rick M Maizels, Cecilia Fernández

“…In the context of the biology of E. granulosus, our analyses reveal: (i) a diverse group of abundant long non-protein coding transcripts showing homology to a middle repetitive element (EgBRep) that could either be active molecular species or represent precursors of small RNAs (like piRNAs); (ii) an up-regulation of fermentative pathways in the tissue of the cyst wall; (iii) highly expressed thiol- and selenol-dependent antioxidant enzyme targets of thioredoxin glutathione reductase, the functional hub of redox metabolism in parasitic flatworms; (iv) candidate apomucins for the external layer of the tissue-dwelling hydatid cyst, a mucin-rich structure that is critical for survival in the intermediate host; (v) a set of tetraspanins, a protein family that appears to have expanded in the cestode lineage; and (vi) a set of platyhelminth-specific gene products that may offer targets for novel pan-platyhelminth drug development.…”
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New technologies and related changes at work as triggers for professional development in the nursing domain: an exploratory interview study by L. Romina Bornhaupt, Regina H. Mulder

“…Data analysis was conducted in a combination of deductive and inductive qualitative content analysis using a concept-driven coding frame. Results Changes in work characteristics were reported for each category of technology. …”
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Characterization of novel human endogenous retrovirus structures on chromosomes 6 and 7 by Nicholas Pasternack, Nicholas Pasternack, Ole Paulsen, Avindra Nath

“…Of these, HERV-K subtype HML-2 is a transposable element that plays a critical role in embryonic development and in the pathogenesis of several diseases. …”
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A virtual-reality (VR) cognitive pupillometry analysis of auditory and visual phonemic awareness tasks involving ‘th’ sound variations by Mohsen Mahmoudi-Dehaki, Nasim Nasr-Esfahani

“…Rooted in the Cognitive Load (CL) and Dual Coding theories, this sequential explanatory study examined the CL levels experienced by 36 available Iranian pre-intermediate English as a Foreign Language (EFL) learners in auditory and visual Phonemic Awareness Tasks (PATs). …”
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Engaging primary care physicians in system change – an interpretive qualitative study in a remote and rural health region in Northern British Columbia, Canada by David Snadden, Trish Reay, Neil Hanlon, Martha MacLeod

“…Flexibility in working from local priorities was a critical part of developing relationships that facilitated the design and implementation of system reform.…”
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A comparative study of ultra-massive MIMO intelligent receivers with adversarial robustness and energy efficiency for 6G applications by Pushkar Nidagundi, Advesh Darvekar, Malik Amber, Ramesh R

“…The findings establish deployment guidelines for mission-critical versus energy-sensitive 6G applications.…”
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Birthing parent perspectives on measuring the quality of perinatal care: metrics, timing, and process by Kristin P. Tully

“…ObjectiveCentering birthing parents is critical for improving reproductive health policies and practices. …”
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Unraveling access barriers and challenges of sexual and reproductive health services for individuals with psychosocial disabilities in Nigeria: insights from family, caregivers, an... by Ibrahim Muhammad Usman, Robert A. C. Ruiter, Schaafsma Dilana

“…Sixty (N = 60) participants were purposively and conveniently selected to include caregivers, and family members of PPSD, and community actors’ who are familiar with mental health issues and its related PSD. Responses were coded and analyzed thematically, guided by the socio-ecological framework.ResultsThe study reported key barriers to SRH access for PPSD, including limited mental health awareness, stigma, financial constraints, and poor healthcare infrastructure. …”
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Smart Infrastructure and Additive Manufacturing: Synergies, Advantages, and Limitations by Antreas Kantaros, Paraskevi Zacharia, Christos Drosos, Michail Papoutsidakis, Evangelos Pallis, Theodore Ganetsos

“…The lack of comprehensive building codes, certification protocols, and quality assurance measures for 3D-printed structures limits their widespread acceptance in mainstream construction. …”
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Genetic variant rs1205 is associated with COVID-19 outcomes: The Strong Heart Study and Strong Heart Family Study. by Lyle G Best, Esther Erdei, Karin Haack, Jack W Kent, Kimberly M Malloy, Deborah E Newman, Marcia O'Leary, Rae A O'Leary, Quan Sun, Ana Navas-Acien, Nora Franceschini, Shelley A Cole

“…<h4>Background</h4>Although COVID-19 infection has been associated with a number of clinical and environmental risk factors, host genetic variation has also been associated with the incidence and morbidity of infection. The CRP gene codes for a critical component of the innate immune system and CRP variants have been reported associated with infectious disease and vaccination outcomes. …”
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Link stability - based optimal routing path for efficient data communication in MANET by Renisha Pulinchuvallil Salim, Rajesh Ramachandran

“…Following this, PCC-SWIFFT methodologies are utilized to generate hash codes, serving as unique identifiers for data packets or routing information. …”
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Multiple copy number variants of VC1 gene reveal single-copy expression as a key determinant of vicine content by Samson Ugwuanyi, Manar Makhoul, Agnieszka A. Golicz, Christian Obermeier, Rod J. Snowdon

“…Moreover, two SNPs within the coding sequence of RIBA2 segregated with v-c content, offering a reliable alternative for marker-assisted selection in faba bean breeding. …”
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“We’re all learning together”: exploring peer educator engagement in Recovery Colleges through a participatory research approach by Betsabeh Parsa, Angela Towle, Sue Macdonald

“…Qualitative data were analyzed using thematic analysis, with coding refined through an iterative process.ResultsWe identified five themes for sustaining peer educator engagement: Inclusivity, Connectedness, Adaptability, Empowerment, and Implementation Factors. …”
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Research Progress on the Functional Regulation Mechanisms of ZKSCAN3 by Jianxiong Xu, Xinzhe Li, Jingjing Xia, Wenfang Li, Zhengding Su

“…The zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) has emerged as a critical regulator of diverse cellular processes, including autophagy, cell cycle progression, and tumorigenesis. …”
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Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene. by Simon Maguire, Jeanne Estabel, Neil Ingham, Selina Pearson, Edward Ryder, Damian M Carragher, Nicolas Walker, Sanger MGP Slc25a21 Project Team, James Bussell, Wai-In Chan, Thomas M Keane, David J Adams, Cheryl L Scudamore, Christopher J Lelliott, Ramiro Ramírez-Solis, Natasha A Karp, Karen P Steel, Jacqueline K White, Anna-Karin Gerdin

“…In humans it has been hypothesised that the 2-oxoadipate mitochondrial carrier coded by SLC25A21 may be involved in the disease 2-oxoadipate acidaemia. …”
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Survival assessment and pre-diagnostic risk factors for lung cancer incidence: Insights from the Golestan Cohort Study. by Seyedeh Fatemeh Mousavi, Sahar Masoudi, Negar Rezaei, Farzad Pourghazi, Maryam Sharafkhah, Maysa Eslami, Akram Pourshams, Hossein Poustchi, Gholamreza Roshandel, Rasoul Aliannejad, Sadaf G Sepanlou, Reza Malekzadeh

“…Our analysis included all cases of lung, tracheal, and bronchial cancers diagnosed under ICD-10 codes C33-C34 from the study's inception to 2022, tracking participants until death. …”
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