Efficacy of Second Generation Direct-Acting Antiviral Agents for Treatment Naïve Hepatitis C Genotype 1: A Systematic Review and Network Meta-Analysis. by Thanthima Suwanthawornkul, Thunyarat Anothaisintawee, Abhasnee Sobhonslidsuk, Ammarin Thakkinstian, Yot Teerawattananon

“…Incidence rates of SVR12 and SVR24, and adverse drug events of each treatment regimen were pooled using 'pmeta' command in STATA program.<h4>Results</h4>Overall, 869 studies were reviewed and 16 studies were eligible for this study. …”
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What drives the development of digital rural life in China? by Chunlin Xiong, Yaling Wang, Zhenyu Wu, Fen Liu

“…Among these configurations, six paths stand out with the highest coverage. These six paths can be further classified into three modes of rural digital life development in China: environment-empowered type, organization-pushed type, and compound-driven type. …”
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Enhancing infectious intestinal disease diagnosis through metagenomic and metatranscriptomic sequencing of 1000 human diarrhoeal samples by Edward Cunningham-Oakes, Blanca M. Perez-Sepulveda, Yan Li, Jay C. D. Hinton, Charlotte A. Nelson, K. Marie McIntyre, Maya Wardeh, Sam Haldenby, Richard Gregory, Miren Iturriza-Gómara, Christiane Hertz-Fowler, Sarah J. O’Brien, Nigel A. Cunliffe, Alistair C. Darby, on behalf of the INTEGRATE consortium

“…Metatranscriptomics gave near-complete transcriptome coverage for Human mastadenovirus F and detected Cryptosporidium via identification of Cryptosporidium parvum virus (CSpV1). …”
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Weighted EHR-based prevalence estimates for hypertension at the state and local levels in Louisiana by Wenjun Li, Meng Zhang, Jie Cheng, Sandra L. Jackson, Adam S. Vaughan, Michael Klompas, Thomas W. Carton, Elizabeth Nauman, Lee Mendoza, Arun Adhikari, Jeanie Donovan, Katherine H. Hohman

“…Methods MENDS, the Multi-State-EHR-Based Network for Disease Surveillance, uses EHR data to calculate chronic disease and risk factor prevalence metrics. …”
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Discovery of Novel Diagnostic Biomarkers for Common Pathogenic <i>Nocardia</i> Through Pan-Genome and Comparative Genome Analysis, with Preliminary Validation by Chaohong Wang, Xinmiao Jia, Ming Wei, Jun Yan, Qing Sun, Sibo Long, Maike Zheng, Yiheng Shi, Guanglu Jiang, Yan Zhao, Hairong Huang, Xinting Yang, Li Gu, Guirong Wang

“…Comparative genome analysis of these core genes with the validation-set gene sequences was then performed using BLAT, with a threshold of 30% amino acid coverage and identity, in order to distinguish specific core genes. …”
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Moisture Content Vegetation Seasonal Variability Based on a Multiscale Remote Sensing Approach by Filippe L. M. Santos, Gonçalo Rodrigues, Miguel Potes, Flavio T. Couto, Maria João Costa, Susana Dias, Maria José Monteiro, Nuno de Almeida Ribeiro, Rui Salgado

“…This work used four dataset sources, collected monthly between June 2022 and July 2023: (i) Vegetation samples used to calculate the LFMC; (ii) Vegetation reflectance spectral signature using the portable spectroradiometer FieldSpec HandHeld-2 (HH2); (iii) Multispectral optical imagery obtained from the Multispectral Instrument (MSI) sensor onboard the Sentinel-2 satellite; and (iv) Multispectral optical imagery derived from a camera onboard an Unmanned Aerial Vehicle Phantom 4 Multispectral (P4M). …”
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Characterisation of between-cluster heterogeneity in malaria cluster randomised trials to inform future sample size calculations by Joseph Biggs, Joseph D. Challenger, Dominic Dee, Eldo Elobolobo, Carlos Chaccour, Francisco Saute, Sarah G. Staedke, Sibo Vilakati, Jade Benjamin Chung, Michelle S. Hsiang, Edgard Diniba Dabira, Annette Erhart, Umberto D’Alessandro, Rupam Tripura, Thomas J. Peto, Lorenz Von Seidlein, Mavuto Mukaka, Jacklin Mosha, Natacha Protopopoff, Manfred Accrombessi, Richard Hayes, Thomas S. Churcher, Jackie Cook

“…The coefficient of variation (k), a measure of such heterogeneity, is typically used in malaria CRTs yet is often predicted without prior data. …”
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Draft genome sequence of first Vibrio diabolicus in Mexico strain InDRE-D1-M1, an emergent threat by Elena Berenice Nava-Soberanes, Edgar Ruben Mendieta-Condado, Fabiola Garcés-Ayala, Adnan Araiza-Rodríguez, Pablo Aguilera-Perez, Alberto Alfaro-López, Alma Cecilia Ibarra-Buelna, Norma Angélica Montes-Colima, Irma López-Martínez, Lucía Hernández-Rivas, Afonso Méndez-Tenorio, Maribel González-Villa, Jorge Membrillo-Hernandez, José Ernesto Ramírez-González, Alma Guadalupe Buelna-Romero

“…Whole genome sequencing was performed using the Miseq system (Illumina, USA). Results: The Multi Locus Sequence Typing profile of the isolated Vibrio bacteria coincided only with 4 specific loci (atpA, gyrB, pyrH and recA) and with a total coverage of the species belonging to Vibrio spp. …”
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Community benefits of mass distribution of three types of dual-active-ingredient long-lasting insecticidal nets against malaria prevalence in Tanzania: evidence from a 3-year clust... by Eliud Andrea Lukole, Jackie Cook, Jacklin F Mosha, Nancy S Matowo, Manisha A Kulkarni, Elizabeth Mallya, Tatu Aziz, Jacklin Martin, Mark Rowland, Immo Kleinschmidt, Alphaxard Manjurano, Franklin W Mosha, Natacha Protopopoff

“…Noticeably, even when usage was ≤ 40% in the chlorfenapyr arm, non-users were better protected than non-users in the higher coverage pyrethroid-only arm. The greater difference in malaria risk observed between users and non-users indicates that LLINs play a crucial role in providing personal protection against malaria infection for the people using the net.…”
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High-LET Proton Irradiation Significantly Alters the Clonogenic and Tumorigenic Potential of Human Breast Cancer Cell Lines In Vitro and In Vivo by Margarita Pustovalova, Rita Mohammad, Yuzhe Wang, Wenyu Xue, Philipp Malakhov, Viktor Nekrasov, Elizaveta Kontareva, Zain Nofal, Vyacheslav Saburov, Dmitry Kolesov, Andreyan Osipov, Sergey Leonov

“…Methods: The relative biological effectiveness (RBE) of PBI was assessed using a clonogenic assay. DNA double-strand break (DSB) repair, epithelial–mesenchymal transition (EMT), and filamentous actin (F-actin) were evaluated using immunofluorescence analysis. …”
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The impact of mass screening and treatment interventions on malaria incidence and prevalence: a retrospective analysis of a malaria elimination programme in eastern Myanmar, and sy... by Jade D. Rae, Angela Devine, Chanapat Patekkham, Aung Myint Thu, Gilles Delmas, Daniel M. Parker, Richard J. Maude, Jacher Wiladphaingern, Ladda Kajeechiwa, May Myo Thwin, Saw Win Tun, Julie A. Simpson, François H. Nosten

“…Results from nine studies identified in the systematic review demonstrate the variable impact of MSAT, which is likely influenced by a variety of factors, including intervention coverage and uptake, baseline malaria endemicity, and methods used for MSAT delivery. …”
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Whole genome and transcriptome analyses identify genetic markers associated with growth traits in Qinchuan black pig by Yaxin Wang, Guangquan Lv, Zhe Liu, Ye Cheng, Rongrong Ding, Gongshe Yang, Taiyong Yu

“…In this study, whole genome and transcriptome analyses revealed the candidate genes associated with growth traits in QCB pigs based on imputed low-coverage whole-genome resequencing data. Results In total, we used 197 low-depth whole-genome resequencing data with an average depth of 3.5X, and then the data were imputed to resequencing data using SWIM reference panel, the imputation accuracy parameters, allele frequency r2 and concordance rate were 0.86 and 95.83%, respectively. …”
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Expanding SCINTIX Biology-Guided Radiotherapy Beyond Lung and Bone: A Planning Feasibility and Dosimetric Study on the RefleXion X1 System by Haozhao Zhang MSc, Grant Gibbard MSc, Chenyang Shen PhD, Thomas I. Banks PhD, Hao Peng PhD, Angela Da Silva PhD, Gopinath Kuduvalli PhD, Todd A. Aguilera MD, PhD, Tu Dan MD, Shahed N. Badiyan MD, Kenneth Westover MD, PhD, David J. Sher MD, Aurelie Garant MD, Raquibul Hannan MD, PhD, Steve B. Jiang PhD, Orhan K. Oz MD, PhD, Robert D. Timmerman MD, Bin Cai PhD

“…Introduction SCINTIX ® therapy, a form of biology-guided radiotherapy using real-time positron emission tomography (PET) imaging on the RefleXion ® X1 platform, recently received FDA clearance for FDG-guided treatment of lung and bone tumors. …”
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Security decision method for the edge of multi-layer satellite network based on reinforcement learning by Peiliang ZUO, Shaolong HOU, Chao GUO, Hua JIANG, Wenbo WANG

“…This paper uses deep reinforcement learning algorithms to implement edge security decisions for satellite networks. …”
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BONE MARROW ASPIRATION: COST ANALYSIS OVER 12 YEARS IN BRAZIL by RC Venâncio, JISD Gomes, AEO Rego, JEB Silva, PRC Passos, JVC Goes, MFD Nascimento, GM Penha, CCV Costa, EBS Martins

“…The data were obtained through a careful process, detailed as follows: The “Tabnet” platform was accessed through DATASUS, followed by selecting the “Health Assistance” axis and the “Ambulatory Production (SIA/SUS)” topic using the “by place of care - from 2008” option, and restricting to “Geographic Coverage”, then to “Brazil and Region by Federal Unit”. …”
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Acceptability, feasibility and appropriateness of integrating HPV self-sampling for cervical cancer screening into voluntary family planning services in Malawi by Patani Mhango, Andrew Kumitawa, Monica Patricia Malata, Jennifer H. Tang, Effie Chipeta, Bianca Kandeya, Medrina Mtende, Princess Kaira, Razak Mussa, Wanangwa Chimwaza, Lameck Chinula, Ireen Magongwa, Jacqueline Mbendera, Eneli Mhango, Eunice Mwandira, Lizzie Msowoya, Jennifer S. Smith, Mitch Matoga, Agatha Bula, Luis Gadama, Victor Mwapasa

“…The World Health Organization recommends cervical cancer screening (CCS) using human papillomavirus (HPV) testing. The coverage of HPV-based CCS is low but may increase with self-sampling of vaginal fluid. …”
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High-throughput method for improving rice AGB estimation based on UAV multi-source remote sensing image feature fusion and ensemble learning by Jinpeng Li, Jinpeng Li, Jinxuan Li, Jinxuan Li, Dongxue Zhao, Dongxue Zhao, Qiang Cao, Qiang Cao, Fenghua Yu, Fenghua Yu, Fenghua Yu, Yingli Cao, Yingli Cao, Yingli Cao, Shuai Feng, Shuai Feng, Shuai Feng, Tongyu Xu, Tongyu Xu, Tongyu Xu

“…However, vegetation indices (VIs) often suffer from saturation due to high canopy coverage and vertical organs, limiting their accuracy across multiple growth stages. …”
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Building evidences in Public Health Emergency Preparedness (“BePHEP” Project)—a systematic review by Michelangelo Mercogliano, Gloria Spatari, Chiara Noviello, Francesca Di Serafino, Maria Elisabetta Mormile, Giuseppa Granvillano, Annalisa Iagnemma, Riccardo Mimmo, Irene Schenone, Eleonora Raso, Andrea Sanna, Enrica Frasson, Veronica Gallinoro, Marcello Di Pumpo, Duha Shellah, Caterina Rizzo, Nunzio Zotti

“…Study quality was assessed using the Joanna Briggs Institute checklist. Results Eleven studies were identified from 1,415 unique articles. …”
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Elimination of lymphatic filariasis as a public health problem in Malawi. by John Chiphwanya, Square Mkwanda, Storn Kabuluzi, Themba Mzilahowa, Bagrey Ngwira, Dorothy E Matipula, Limbikani Chaponda, Paul Ndhlova, Prince Katchika, Chawananga Mahebere Chirambo, Philemon Moses, Justin Kumala, Martin Chiumia, Carrie Barrett, Hannah Betts, Joan Fahy, Maria Rebollo Polo, Lisa Reimer, Michelle C Stanton, Brent Thomas, Sian Freer, David H Molyneux, Moses J Bockarie, Charles D Mackenzie, Mark J Taylor, Sarah Martindale, Louise A Kelly-Hope

“…First, to stop the spread of infection (i.e., interrupt transmission) and reduce the circulating filarial antigen prevalence from as high as 74.4% to below the critical threshold of 1-2% prevalence, mass drug administration (MDA) using a two-drug regime was implemented at high coverage rates (>65%) of the total population, with supplementary interventions from other programmes (e.g., malaria vector control). …”
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A novel three-dimensional navigation technology for ultrasound-guided transcarotid artery revascularization by William R. Warner, MEM, Kirthi S. Bellamkonda, MD, MSc, Richard J. Powell, MD, Roberta M. diFlorio-Alexander, MD, MS, Keith D. Paulsen, PhD, Xiaoyao Fan, PhD

“…Technical success was assessed in terms of lesion coverage by the stent placed using the coregistered (to pre-procedure CT) US image guidance. …”
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