Primary healthcare expansion and mortality in Brazil's urban poor: A cohort analysis of 1.2 million adults. by Thomas Hone, Valeria Saraceni, Claudia Medina Coeli, Anete Trajman, Davide Rasella, Christopher Millett, Betina Durovni

“…This study evaluates the impact of an ambitious program to rapidly expand FHS coverage in the city of Rio de Janeiro, Brazil, since 2008.…”
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A comprehensive strategy for the development of a multi-epitope vaccine targeting Treponema pallidum, utilizing heat shock proteins, encompassing the entire process from vaccine de... by Jing Jiang, Jing Jiang, Linglan Xu, Linglan Xu, Xuefeng Wang, Ming Wang, Youde Cao, Ranhui Li, Kang Zheng, Xian Wu

“…The population coverage of the designed vaccine was 94.41% worldwide. …”
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IMMUNOLOGICAL AND MORPHOLOGICAL PREDICTORS OF CLINICAL HETEROGENEITY OF PATIENTS WITH GRAVES' DISEASE (BASED ON RESEARCH OF THE THYROID GLAND OPERATIONAL MATERIAL) by T. V. Saprina, T. S. Prokhorenko, N. V. Ryazantseva, I. N. Vorozhtsova, S. Yu. Martynova, A. N. Dzyuman, A. P. Zima, O. S. Popov, I. A. Khlusov, K. T. Kasoyan, I. P. Shabalova

“…The study included: definition of the standard for GD hormonal and serological profile (free T4, free T3, and TSH, antibodies to TPO, antibodies to the TSH receptor), the cultivation of mononuclear leukocytes in complete culture medium within 24 hours with subsequent determination of interleukins concentrations (IL-2, IL-4, TNF-alpha) in culture medium using enzyme-linked immunosorbent assay, determination of the number of blood cells carrying membrane-bound receptors to IL-2, IL-4, TNF-R1 by flow laser cytometry on cytometer BD FACS Canto tmΙΙ (USA) using labeled monoclonal antibody, the standard postoperative histological examination of thyroid gland tissue samples and immunohistochemical detection in samples of thyroid tissue receptors to IL-2, IL-4, TNF-alpha.Results. …”
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Advances in plant-based raw materials for food 3D printing by Zhihao Liu, Xinna Hu, Shuyu Lu, Bo Xu, Chenyu Bai, Tao Ma, Yi Song

“…Three-dimensional (3D) printing is an emerging technology in the food industry, and in recent years, with its unique advantages, it has been widely used in the food industry. Its organic combination with food production provides customization, personalization, and intelligent features. …”
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Genome-wide association study for numbers of vertebrae in Dezhou donkey population reveals new candidate genes by Yan SUN, Chang-heng ZHAO, Jun TENG, Yong-hui WANG, Tian-qi WANG, Xiao-yuan SHI, Zi-wen LIU, Hai-jing LI, Ji-jing WANG, Wen-wen WANG, Chao NING, Chang-fa WANG, Qin ZHANG

“…A genome-wide association study was conducted using whole genome sequence data imputed from low-coverage genome sequencing. …”
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Benefits and challenges of host depletion methods in profiling the upper and lower respiratory microbiome by Chun Wang, Li Zhang, Chuanwen Kan, Junyan He, Weijie Liang, Ruiyan Xia, Linyu Zhu, Jing Yang, Xuan Jiang, Wentai Ma, Zhihang Liang, Zhiqing Xiao, Juanjuan Zhang, Jiaxin Zhong, Xiao Sun, De Chang, Zhang Wang, Guoliang Zhang, Mingkun Li

“…In this study, we benchmarked seven host depletion methods, including a new method (F_ase), using bronchoalveolar lavage fluid (BALF), oropharyngeal swab (OP), and mock samples. …”
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Intranasal trivalent candidate vaccine induces strong mucosal and systemic immune responses against Neisseria gonorrhoeae by Qin Lu, Hui Yang, Hui Yang, Yanfeng Peng, Yanfeng Peng, Zeling Dong, Zeling Dong, Pujing Nie, Pujing Nie, Guangli Wang, Guangli Wang, Shilu Luo, Shilu Luo, Xun Min, Xun Min, Jian Huang, Jian Huang, Meirong Huang

“…Therefore, increasing the coverage of vaccination by using a multivalent vaccine may be more effective. …”
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Study of the Stability and Anti-Inflammatory Activity of Paeonol–Oleanolic Acid Liposomes by Microfluidic Technology by Xianzheng Ma, Hui Zhang, Jinkai Luan, Mingfa Tian, Xiuxin Zhang, Ammara Sohail, Dong Liang, Jiguo Liu, Fuzhan Tao, Zheng Wang, Daijie Wang

“…(1) Background: This study used a microfluidic approach to prepare paeonol (PAE) liposomes with oleanolic acid (PAE-ONLs) instead of cholesterol (PAE-CNLs), aiming to reduce cholesterol levels and enhance stability and anti-inflammatory activity. (2) Methods: The liposome formula was optimized, characterized, and tested for anti-inflammatory activities in zebrafish and RAW 264.7 macrophages, utilizing various stability and molecular interaction methods. (3) Results: The best PAE-ONL preparation conditions were 10.25 mg/mL of soy lecithin, 0.82 mg/mL of oleanolic acid, and 0.22% (wt%) of Tween 80, with an <i>EE</i> of 64.61 ± 0.42%. …”
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Comprehensive metabolomic/lipidomic characterization of patients with mitochondrial ATP synthase, short-chain acyl-CoA dehydrogenase and combined variant deficiencies by Dana Dobešová, Matúš Prídavok, Radana Brumarová, Aleš Kvasnička, Barbora Piskláková, Eliška Ivanovová, Katarína Brennerová, Jana Šaligová, Ľudmila Potočňáková, Simona Drobňaková, Jana Potočňáková, David Friedecký

“…Analyses were conducted using high-performance liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). …”
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Joint external evaluation of the International Health Regulation (2005) capacities: current status and lessons learnt in the WHO African region by Ibrahima Socé Fall, Ali Ahmed Yahaya, Ambrose Talisuna, Soatiana Cathycia Rajatonirina, Mary Stephen, Antonio Oke, Allan Mpairwe, Amadou Bailo Diallo, Emmanuel Onuche Musa, Daniel Yota, Freddy Mutoka Banza, Roland Kimbi Wango, Nathalie Amy Roberts, Rajesh Sreedharan, Nirmal Kandel, Adrienne May Rashford, Linda Lucy Boulanger, Qudsia Huda, Stella Chungong, Zabulon Yoti

“…From February 2016 to March 2019, 40 of 47 WHO African region countries (81% coverage) evaluated their IHR capacities using the JEE tool. …”
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Quantifying the dosimetric impact of online daily adaptation for MR-guided RT in cervical cancer by Amerah Alshamrani, Robert Chuter, Marianne Aznar, Peter Hoskin, Claire Nelder, Ananya Choudhury, Lisa Barraclough, Cynthia L. Eccles

“…Methods: A retrospective analysis of five node-negative, locally advanced cervical cancer patients treated under the MOMENTUM study (NCT04075305) using adapt-to-shape (ATS) on an Elekta Unity MR-Linac. …”
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It depends on how you tell: a qualitative diagnostic analysis of the implementation climate for community-wide mass drug administration for soil-transmitted helminth by Judd L Walson, Saravanakumar Puthupalayam Kaliappan, Sitara Swarna Rao Ajjampur, Sarah Lawrence, Khumbo Kalua, Euripide Avokpaho, Amy Roll, Angelin Titus, Yesudoss Jacob, Marie Claire Gwayi-Chore, Félicien Chabi, Comlanvi Innocent Togbevi, Abiguel Belou Elijan, Providence Nindi, Moudachirou Ibikounle, Kumudha Aruldas, Arianna Rubin Means

“…We used the Consolidated Framework for Implementation Research to guide the design of the interview guide and thematic analysis.Results Across all three sites, aspects of the implementation climate that were facilitators to cMDA launch included: high community member demand for cMDA, integration of cMDA into existing vaccination campaigns and/or health services, and engagement with familiar health workers. …”
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A Phase 3 Randomized Trial Investigating the Safety, Tolerability, and Immunogenicity of V116, an Adult-Specific Pneumococcal Vaccine, Compared with PPSV23, in Adults ≥50 Years of... by Veronika Jotterand, Vinita Jagannath, Andrea Accini Diaz, Juan Diego Velez, Arna Letica, Silvia Narejos Perez, Rebecca Clark, Yoseph Caraco, Olaf Degen, Kyung-Hwa Park, Serhat Ünal, Frederick Wittke, Kimberly Hurtado, Clay Churchill, Ying Zhang, Doreen Fernsler, Jianing Li, Ulrike K. Buchwald, Heather Platt

“…<b>Interpretation</b>: In regions with established vaccination programs, V116 could broaden the serotype coverage for residual pneumococcal disease in adults.…”
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The state of COVID-19 contact tracing following relaxation of the national lockdown: A qualitative study among surveillance response teams in Kampala, Uganda by Andrew Kuguminkiriza Tusubira, Steven Ssendagire, Angela Nakanwagi Kisakye, Elizabeth Muhumuza, Dorothy Akong, Winnie Agwang, David Kansiime, Stella Martha Migamba, Doreen Tuhebwe, Elizabeth Ekirapa Kiracho

“…Interviews were audio recorded and transcribed verbatim. We used a conventional approach for content analysis to identify emergent themes. …”
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Performance of RIS-Secured Short-Packet NOMA Systems With Discrete Phase-Shifter to Protect Digital Content and Copyright Against Untrusted User by Nguyen Quang Sang, Hye-Young Kim, Tan N. Nguyen, Minh Bui Vu, Phuong T. Tran, Tran Trung Duy, Byung-Seo Kim, Miroslav Voznak

“…On this foundation, we derive closed-form expressions for the average block-error rate (BLER) to analyze the performance of trustworthy users as well as the average secure BLER to quantify the secure performance when untrustworthy users wiretap trustworthy users&#x2019; information using successive interference mechanisms. Moreover, we further develop asymptotic expressions for both cases to measure the diversity gain and induce key parameters. …”
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Impact and elastic modulus of coal mining on terrestrial ecosystems by Jihong Dong, Wenting Dai, Jiren Xu, Hui Zhang, Yunpeng Li, Fei Xie

“…Identifying the impact of coal mining on terrestrial ecosystems and adopting resilient recovery measures are crucial prerequisites for advancing green coal mining efforts and attaining carbon peaking and carbon neutrality goals. Using China’s open-pit coal mining as a case study: (1) the research examines the fundamental attributes and evolving patterns of spatial distribution among these mines within the country. …”
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Utilization and Determinants of Antenatal Care Visits in East African Countries: A Multicountry Analysis of Demographic and Health Surveys by Zemenu Tadesse Tessema, Amare Minyihun

“…This study aimed to identify the utilization and determinants of attending at least four visits in 12 East African countries. Methods. The study used the demographic and health survey data from 12 East African countries from 2008 to 2018. …”
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Long-term hydro-economic analysis tool for evaluating global groundwater cost and supply: Superwell v1.1 by H. Niazi, S. B. Ferencz, N. T. Graham, J. Yoon, T. B. Wild, M. Hejazi, D. J. Watson, C. R. Vernon

“…We also demonstrate and discuss examples of how these cost curves could be used by linking Superwell's outputs with other models to explore coupled human–environmental system challenges, such as water resources planning and management, or broader analyses of multisectoral feedbacks.…”
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Importance of four-dimensional computed tomography simulation in locally advanced lung cancer radiotherapy: Impact on reducing planning target volume by Marić Slavica, Janjić Petar, Bosančić Borut, Mijailović Milan, Lukić Snežana

“…Four-dimensional (4D) computed tomography (CT) simulation is a useful tool for motion assessment in lung cancer radiotherapy. …”
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Climate variability off Africa's southern Cape over the past 260&thinsp;000 years by K. Purcell, K. Purcell, K. Purcell, M. H. Simon, M. H. Simon, M. H. Simon, E. J. Pryor, E. J. Pryor, S. J. Armitage, S. J. Armitage, H. J. L. van der Lubbe, E. Jansen, E. Jansen, E. Jansen

“…X-ray fluorescence (XRF) core scanning, calibrated with discrete samples analysed by XRF spectroscopy, was used to determine the variability in the bulk elemental composition of the core over time. …”
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