<i>Folliculin</i> (<i>FLCN</i>) in Thyroid Tumors: Incidence, Significance, and Role as a Driver Gene and Secondary Alteration by Faisal A. Hassan, Camryn Slone, Robert J. McDonald, Julie C. Dueber, Adeel M. Ashraf, Melina J. Windon, Oliver J. Fackelmayer, Cortney Y. Lee, Therese J. Bocklage, Derek B. Allison

“…The lack of <i>FLCN</i> coverage in standard thyroid molecular panels likely underestimates its clinical relevance. …”
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Evaluation of secondary prevention of noncommunicable diseases at the outpatient healthcare level in the Commonwealth of Independent States countries by M. N. Mamedov, V. A. Kutsenko, T. Z. Seisembekov, S. Kh. Mekhdiev, L. V. Yakubova, L. V. Kezhun, I. T. Murkamilov, Zh. A. Kauzbay, B. Zholdin, O. M. Drapkina

“…The survey was carried out using an original questionnaire of the National Medical Research Center for Therapy and Preventive Medicine, which consisted of 11 blocks of questions. …”
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Global, regional, and national estimates of the impact of a maternal Klebsiella pneumoniae vaccine: A Bayesian modeling analysis. by Chirag K Kumar, Kirsty Sands, Timothy R Walsh, Seamus O'Brien, Mike Sharland, Joseph A Lewnard, Hao Hu, Padmini Srikantiah, Ramanan Laxminarayan

“…<h4>Methods and findings</h4>We developed a Bayesian mixture-modeling framework to estimate the effects of a hypothetical K. pneumoniae maternal vaccine with 70% efficacy administered with coverage equivalent to that of the maternal tetanus vaccine on neonatal sepsis infections and mortality. …”
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Rectal Cancer and Lateral Lymph Node Staging: Interobserver Agreement and Success in Predicting Locoregional Recurrence by Hüseyin Akkaya, Okan Dilek, Selim Özdemir, Turgay Öztürkçü, Mustafa Gürbüz, Zeynel Abidin Tas, Süleyman Çetinkünar, Bozkurt Gülek

“…The patients were evaluated according to locoregional rectal cancer and lateral lymph node (LLN) staging, and re-staging was performed using MRI images after neoadjuvant treatment. The ability of the locoregional and LLN staging system to predict locoregional recurrence was evaluated. …”
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Investigation and application of data balancing and combined discriminant model in rock burst severity prediction by Shaohong Yan, Runze Liu, Yanbo Zhang, Xulong Yao, Yueqi Yang, Qi Wang, Bin Guo, Shuai Wang

“…Abstract In the development of intelligent rock burst prediction models, issues such as incomplete data coverage and data imbalance are frequently encountered. …”
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Evaluation of Vaccination Status, Awareness, and Seroprevalence of Hepatitis B Virus Infection among Female Sex Workers in Jos by Hashimu Zakari, Adaobi Vivian Okafor, Y Abubakar Ajang, Jude Y Nkup, Ramman Selvyat Katnap

“…Blood samples were collected using the RecombiLISAHbsAg ELISA kit (CTK Biotech Inc., San Diego, USA) to qualitatively detect HBsAg.Twenty (21) out of the 86 subjects tested positive, yielding a 24.4% prevalence rate.  …”
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Variation patterns of different vegetation types and soil nutrients in water-land ecotone of the Li River by WANG Jing1,2, PAN Fujing3, LU Qianqian2, WANG Bin1*

“…To promote the restoration and reconstruction of ecosystem in the water-land ecotone, based on typical sample investigation, the variation patterns of vegetation species composition and diversity, and soil nutrients under different vegetation types were studied using Pearson correlation coefficient method and redundancy analysis method. …”
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Multi-omics analysis of methylmalonic acidemia caused by a non-coding region variant in MMAA gene combined with uniparental disomy by HUO Xiaoyan, LUO Xiaomei, YE Xiantao, SUN Yu, YU Yongguo, LIANG Lili, FAN Yanjie

“…Objective·To investigate the genetic etiology of a rare and complex case clinically suspected to be methylmalonic acidemia (MMA), but with negative whole exome sequencing (WES) results, using a multi-omics sequencing approach.Methods·DNA and RNA samples were extracted from the peripheral blood of the proband and both parents. …”
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Tacrolimus eye drops treatment for recurrent exposure of the Ahmed glaucoma valve tube by Li-Li Chen, Yu Chen, Lin Fu, Li-Qing Wei, Wei-Hua Pan

“…Four eyes were treated with allogeneic scleral patch transplantation, while two eyes were repaired using autologous conjunctival transplants. The primary clinical manifestations in both groups were bulbar conjunctival perforations and erosion. …”
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Soil Erosion and Spatio-temporal Variations in Huangshui River Basin Based on MODIS and Landsat Data by Du Mei, Zhao Jianyun, Yang Jing, Ding Yuanyuan, Liu Wenhui, Li Guorong, Wang Zushun, Zhao Lijiang

“…[Methods] Based on MODIS and Landsat images, precipitation, population density, and the economy in 2000 and 2018, we used low altitude UAV remote sensing, the RUSLE model, and geostatistics to calculate, validate, and analyze the spatio-temporal variability of a soil erosion model in the Huangshui River basin. …”
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Flood Risk Assessment in Coastal Cities: A Case Study of Lingang New City, Shanghai by CHEN Li-hui, CHEN Jie, GAO Guo-ping

“…A high-resolution grid unit of 30m × 30m was innovatively adopted, and a combined subjective-objective weighting approach was used by integrating the Analytic Hierarchy Process (AHP) and the entropy weight method. …”
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The economic burden of breast cancer in western Iran: a cross-sectional cost-of-illness study by Banafsheh Darvishi Teli, Meysam Behzadifar, Mania Beiranvand, Aziz Rezapour, Seyed Jafar Ehsanzadeh, Samad Azari, Ahad Bakhtiari, Payam Haghighatfard, Mariano Martini, Maryam Saran, Masoud Behzadifar

“…Methods A retrospective cost-of-illness analysis utilizing a cross-sectional design was performed from November 2023 to July 2024. Data were collected using patient medical records and telephonic interviews. …”
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Assessing five-year trend and socio-demographic determinants of caesarean section delivery in Ghana by Alfred Kwesi Manyeh, Anthony Ofosu, Anthony Kolsabilik Kuug, Atsu Ayi, Comfort Dede Tetteh, Saviour Edem Vidzro, Christopher Tetteh Odopey, Angela Nana Esi Ackon, Evelyn Acquah, Desmond Klu, Mustapha Immurana, Maxwell Ayindenaba Dalaba, Hubert Amu

“…This study aims to assess the trend and factors associated with CS deliveries in Ghana using secondary data from the District Health Information Management System 2 (DHIMS-2) database. …”
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Measure selection for an electronic patient-reported outcome (ePRO) system for CAR T-cell therapy patients: a modified Delphi consensus studyResearch in context by Sarah E. Hughes, Foram Khatsuria, Christel McMullan, Karen L. Shaw, Anita Walker, Francesca Kinsella, David Burns, Olalekan L. Aiyegbusi, Elin Haf Davies, John Ansell, Evelyn Chakera, Charles Craddock, Alastair Denniston, Rebecca Lloyd, Paul Ferguson, Ronjon Chakraverty, Melanie Calvert

“…Interpretation: In the absence of guidance on PRO measure selection for CAR T-cell therapies, consensus-based methods represent an important step towards use of PROs with this clinical population. Modest sample size and representativeness of the patient subgroup are limitations of this study. …”
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Trends, risk factors, and outcomes of unplanned extubation in a neonatal intensive care unit: a seven-year retrospective study by Kamal Ali, Kamal Ali, Kamal Ali, Mohammed Almahdi, Mohammed Almahdi, Saleh S. Algarni, Saleh S. Algarni, Saleh S. Algarni, Saif Alsaif, Saif Alsaif, Saif Alsaif, Reem O. Alharbi, Maisa A. Alqahtani, Rashed Aldubaian, Malak Alsharif, Mark Castro, Abigail Esclanda, Manal Althubaiti, Mohanned Alrahili, Musaab Alshareef, Abdulaziz Homedi, Ibrahim Ali

“…Trends in UE rates over the seven-year study period were analyzed using linear regression. Logistic regression analysis was performed to identify predictors of reintubation following UE.ResultsA total of 175 UE episodes were recorded over the study period. …”
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Identification of OqxB Efflux Pump and Tigecycline Resistance Gene Cluster tmexC3D2-toprJ3 in Multidrug-Resistant Pseudomonas Stutzeri Isolate G3 by Amande TJ, Kaszyk V, Brown F

“…Tivkaa Joseph Amande,1,2 Vanessa Kaszyk,2 Fiona Brown2 1School of Life and Health Sciences, University of Roehampton, London, UK; 2Department of Biological Sciences, University Centre Peterborough, Part of Inspire Education Group, Peterborough, UKCorrespondence: Tivkaa Joseph Amande, School of Life and Health Sciences, Parkstead House, Whitelands College, University of Roehampton, London, SW15 4JD, UK, Tel +44 (0)20 8392 3531, Email tivkaa.amande@roehampton.ac.ukPurpose: To identify antibiotic resistance genes (ARGs) and understand the molecular basis of multidrug resistance in P. stutzeri isolate G3.Methods: Whole-genome sequencing of isolate G3 was conducted at 30X coverage using Illumina NovaSeq 6000. Reads were trimmed using Trimmomatic and assessed using a combination of scripts that incorporated Samtools, BedTools, and bwa-mem. …”
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Optimization design of liquid crystal-based reconfigurable intelligent surface-assisted indoor visible light communication systems by Lisu YU, Xinxin LÜ, Run ZHONG, Mingli ZHANG, Zhenghai WANG, Yuhao WANG

“…To overcome such obstacles, reconfigurable intelligent surfaces (RISs) have been effectively used in wireless networks. Meta-surface-based simultaneous transmission and reflection reconfigurable intelligent surfaces (STAR RISs) have emerged to address LoS blockage and provide 360° coverage in radio-frequency wireless systems. …”
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Forest aboveground biomass retrieval integrating ICESat-2, Landsat-8, and environmental factors by Sunjie Ma, Jisheng Xia, Chun Wang, Zhifang Zhao, Fuyan Zou, Maolin Zhang, Guize Luan, Ci Li, Xi Tu, Letian Li

“…In the AGB retrieval model using canopy metrics, mean canopy height, relative canopy height, canopy coverage, and canopy quadratic mean were strong predictors (correlation coefficients of 0.67, 0.65, 0.63, and 0.62, respectively). …”
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Expectation Confirmation and Technology Acceptance: A Study of the Public's Attention to Accept the Government's Digital Human Avatar by Jinghao CHEN, Feng JIA, Qianxi LIU

“…The data were analyzed using structural equation modeling (SEM), which provides robust statistical insights into the relationships between these constructs. …”
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Polygenic risk score prediction accuracy convergence by Léo Henches, Jihye Kim, Zhiyu Yang, Simone Rubinacci, Gabriel Pires, Clara Albiñana, Christophe Boetto, Hanna Julienne, Arthur Frouin, Antoine Auvergne, Yuka Suzuki, Sarah Djebali, Olivier Delaneau, Andrea Ganna, Bjarni Vilhjálmsson, Florian Privé, Hugues Aschard

“…Our analyses suggest that increasing the variant coverage of PRS, using either more imputed variants or sequencing data, is a key component for future improvements in prediction accuracy.…”
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