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Mathematical assessment of the optimal intervention strategy for Cercospora fungal disease in orange plants
Published 2025-06-01“…Cercospora fragariae is a fungal plant pathogen. Citrus trees and shrubs are particularly vulnerable to Cercospora infections, which can result in significant crop losses. …”
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Prevalence and penetrance of pathogenic and likely pathogenic LDLR and APOB gene variants linked to familial hypercholesterolemia and increased risk of ischemic heart disease
Published 2025-08-01“…Such informed screening would facilitate early identification of at-risk individuals, enabling timely intervention and management.MethodsWe analyzed genetic data from 4,856 individuals with various cardiovascular conditions for pathogenic and likely pathogenic variants in the PCSK9, APOB, and LDLR genes. …”
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Antibiotics’ collateral effects on the gut microbiota in the selection of ESKAPE pathogens
Published 2024-11-01“…Background: ESKAPE pathogens, consisting of Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp., labelled high-priority by WHO, evade antibiotics, posing treatment challenges and escalating healthcare costs. …”
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Antimicrobial resistance in foodborne pathogens: consequences for public health and future approaches
Published 2025-06-01“…Abstract Foodborne pathogen-associated antimicrobial resistance (AMR) is a major global public health concern, complicating infection control and placing another strain on medical resources. …”
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Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation.
Published 2024-05-01“…Health economic assessments found that, for SA-type interventions, the amount one could spend on control whilst maintaining a cost-effective intervention (termed threshold unit intervention cost) was very sensitive to the strength of symptom propagation.…”
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A paper-based loop-mediated isothermal amplification assay for highly pathogenic avian influenza
Published 2025-04-01“…Therefore, prompt, reliable, and cost-effective diagnostic devices are crucial for scrutinizing and confining highly pathogenic avian influenza viruses (HPAIVs). …”
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Budget impact analysis of routinely using whole-genomic sequencing of six multidrug-resistant bacterial pathogens in Queensland, Australia
Published 2021-02-01“…Objective To predict the cost and health effects of routine use of whole-genome sequencing (WGS) of bacterial pathogens compared with those of standard of care.Design Budget impact analysis was performed over the following 5 years. …”
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Healthy homes: Stakeholder perspectives on housing interventions to reduce environmentally mediated infections.
Published 2025-01-01“…Funding and financial mechanisms to address housing interventions were highlighted as key barriers, alongside the need to provide more rigorous evidence and cost-benefit analyses for housing interventions. …”
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Enhancing bloodstream infection diagnostics: a novel filtration and targeted next-generation sequencing approach for precise pathogen identification
Published 2025-03-01“…Next-generation sequencing (NGS) is a powerful tool for rapid, precise pathogen identification. While metagenomic NGS (mNGS) offers broad pathogen coverage, it is often costly and complex. …”
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Recent Advances in Biosensor Technologies for Meat Production Chain
Published 2025-02-01“…Biosensors are innovative and cost-effective analytical devices that integrate biological recognition elements (bioreceptors) with transducers to detect specific substances (biomolecules), providing a high sensitivity and specificity for the rapid and accurate point-of-care (POC) quantitative detection of selected biomolecules. …”
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A Smart Semi‐Implantable Device Integrating Microchannel‐Enhanced Sampling and Multiplex Biochemical Testing for Deep Wound Monitoring and Pathogen Identification
Published 2025-02-01“…The device's capability to rapidly and accurately identify pathogenic bacteria is also demonstrated both in vitro and in vivo, potentially facilitating precise intervention in infected wounds. …”
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Seasonal Dynamics and Legionellosis-Associated Hospitalization in Spain: A Retrospective Study
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Development of a Multiplex Real-Time PCR Assay for the Detection of Eight Pathogens Associated with Bovine Respiratory Disease Complex from Clinical Samples
Published 2025-07-01“…In conclusion, the developed multiplex qPCR assay provides a reliable, rapid, and cost-effective tool for simultaneous detection of multiple BRDC-associated pathogens, which will hold great promise for enhancing disease surveillance, early diagnosis, and targeted intervention strategies, ultimately contributing to improved BRDC management and cattle health outcomes.…”
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A Review of Swine Breeding Herd Biosecurity in the United States to Prevent Virus Entry Using Porcine Reproductive and Respiratory Syndrome Virus as a Model Pathogen
Published 2024-09-01“…Biosecurity protocols must be science-based, a way of life, continuously validated, cost-effective, and benchmarked over time. This paper will review these concepts, the direct and indirect routes of transmission of porcine reproductive and respiratory syndrome virus (PRRSV), and the interventions that have been designed and validated to prevent infection of the breeding herd. …”
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Discovery of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> Lytic Phages with Extensive Host Range Across Rapid- and Slow-Growing Pathogenic Mycobacterial Species
Published 2024-10-01“…Background/Objectives: Developing interventions for Johne’s disease, which focuses on controlling <i>Mycobacterium avium</i> subsp. …”
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Cost-effectiveness of wastewater-based environmental surveillance for SARS-CoV-2 in Blantyre, Malawi and Kathmandu, Nepal: A model-based study.
Published 2025-01-01“…Implementing ES for multiple pathogens may improve its cost-effectiveness.…”
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Climate change and plant protection: challenges and innovations in disease forecasting systems in developing countries
Published 2025-07-01“…This proactive approach assesses the likelihood of disease outbreaks and increases in disease intensity, enabling timely intervention and resource optimization. However, climate change exacerbates this challenge by altering pathogen evolution and host-pathogen interactions, fostering the emergence of new pathogenic strains, shifting pathogen ranges, and expanding the geographic spread of plant diseases. …”
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Clean Hands, Safe Care: Role of hand hygiene training interventions in improving knowledge and Hand hygiene compliance rate among healthcare workers
Published 2025-03-01“…Background: Hand hygiene (HH) is proven low-cost crucial intervention to curtail the problem of hospital-acquired infection (HAI). …”
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Immunogenicity, Pathogenesis, and Host’s Immuno-Responses to Marburg Virus Infection
Published 2025-03-01“…Due to the sudden emergence and burnout nature of Marburg virus (MARV) outbreaks, little is known about MARV’s pathogenicity and immunogenicity. These gaps in knowledge are limiting our understanding of the disease and the implementation of cost-effective prevention and control measures including case management through safe and effective therapeutic modalities. …”
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