Srebf2 mediates successful optic nerve axon regeneration via the mevalonate synthesis pathway by Mengming Hu, Matthew B. Veldman

“…Results LCM-seq comparison of uninjured versus 3-day post ON injury RGCs identified significant upregulation of the cholesterol synthesis pathway during axon regeneration. …”
Get full text

Risks and benefits of artificial intelligence deepfakes: Systematic review and comparison of public attitudes in seven European Countries by Nik Hynek, Beata Gavurova, Matus Kubak

Get full text

Attention as the basic component of cognitive functions of the brain and its features in children with bronchial asthma by S. M. Nedelska, О. Yu. Akulova, Т. Ye. Shumna

“…To study the characteristics of attention in children with bronchial asthma (BA) taking into account their sex differences, depending on the course, duration and control of the disease. Materials and methods. …”
Get full text

An fMRI study of crossmodal emotional congruency and the role of semantic content in the aesthetic appreciation of naturalistic art by Funda Yilmaz, Tessa M. van Leeuwen, Tessa M. van Leeuwen, Umut Güçlü, Yağmur Güçlütürk, Rob van Lier

“…This demonstrates that emotional congruency not only increased beauty ratings but also increased the in-depth processing of the paintings. For incongruent versus congruent comparisons, the results suggest that a frontoparietal network and caudate may be involved in emotional incongruency. …”
Get full text

Increased Serum Concentrations of TNF-Like Weak Inducer of Apoptosis Predict Higher 28-Day Mortality in Patients with Sepsis by Ying Guo, Manyi Ren, Lili Ge, Chao Sun, Rui Li, Cheng’en Ma, Shujian Sui

“…The serum levels of TWEAK were significantly lower in septic patients compared to controls (417.4 ± 196.7 pg/ml versus 1243.8 ± 174.3 pg/ml, p<0.001). …”
Get full text

Results of a cluster randomized trial testing the Systems Analysis and Improvement Approach to increase cervical cancer screening in family planning clinics in Mombasa County, Keny... by McKenna C. Eastment, George Wanje, Barbra A. Richardson, Emily Mwaringa, Shem Patta, Kenneth Sherr, Ruanne V. Barnabas, Kishorchandra Mandaliya, Walter Jaoko, R. Scott Mcclelland

“…Methods Twenty FP clinics in Mombasa County were randomized 1:1 to SAIA versus usual procedures. SAIA has five steps: (1) cascade analysis tool to understand the cascade and identify inefficiencies, (2) sequential process flow mapping to identify bottlenecks, (3) develop and implement workflow modifications (micro-interventions) to address identified bottlenecks, (4) assess the micro-intervention in the cascade analysis tool, and (5) repeat the cycle. …”
Get full text

Pentoxifylline Enhances Sperm Quality, Reduces Oxidative Stress in Semen, and Decreases Sperm DNA Damage in Men with Asthenozoospermia Undergoing Assisted Reproductive Technology by Oumaima Ammar, Marwa Ben Ali Gannoun, Tesnim Ajina, Assila Hadj Ali, Manel Boussabbeh, Amira Sallem, Zohra Haouas, Mariarosaria Di Tommaso, Meriem Mehdi

“…The sperm samples treated with PTX, compared to the controls, exhibited a significant increase in total sperm motility (71.8 ± 23.03% versus 47.47 ± 4.88%, respectively; <i>p</i> < 0.0001). …”
Get full text

Thermal behavior and switching losses of MOSFET in high-frequency transformer circuits by Jiale Cheng, Yinghao Zhang, Xiangqun Cheng, Kaixin Guo, Yuchen Wang, Mian Jiang, Yabin Wang, Yang Liu

Get full text

Strategy to Reduce Mortality Rates of ST-elevation Acute Myocardial Infarction Using Prehospital Thrombolysis: A Meta-analysis by Barathkumar Ramadoss, Arun Pari, Sharanya Shre Ezhil Santhi, Sailatha Ravi, Ezhilarasan Ramanan

“…Data Sources: In December 2020, the Cochrane search strategy was used to analyze randomized control trials, nonrandomized control studies, and registry studies in PubMed, EMBASE, Cochrane Library, Google Scholar, ClinicalKey, and Clinical Trial Registries. …”
Get full text

Tumour microenvironment markers in spontaneous and induced incubation of breast cancer biopsies by Yu. S. Gergenreter, N. B. Zakharova, O. L. Morozova

“…In group 2, a pronounced vascularization was more often observed: in 6 (40%) patients versus 1 (7%) in group 1 (p &lt; 0.05). In both groups, compared with the control, there was a statistically sig-nificant (p &lt; 0.05) increase in spontaneous production of TNF-α by 4.2 and 4.8 times, MCP-1 by 6.7 and 6.3 times, TGF-β1 – 2.2 and 2.5 times, VEGF 11.9 and 14.6 times; GM-CSF 15.6 and 13.4 times, G-CSF 96.8 and 79.5 times, respectively. …”
Get full text

Effect of midlife exercise on lipid metabolism in aging mice: comparable to lifelong exercise, better than ceasing midlife exercise by Ling Yang, Tuanhui Peng, Xu Yan, Pengjie Lin

“…Abstract This study examines the effects of continuous versus interrupted lifelong exercise on lipid metabolism in naturally aging male BALB/c mice. …”
Get full text

Machine vision system combined with multiple regression for damage and quality detection of bananas during storage by Mai Al-Dairi, Pankaj B. Pathare, Rashid Al-Yahyai, Nasser Al-Habsi, Hemanatha Jayasuriya, Zahir Al-Attabi

“…The study used a machine vision system and applied image process analysis to assess the bruise parameters of the damage zone and external quality attributes of 18 treatments generated from bruised (30 cm and 60 cm drop heights) and non-bruised (control) ‘Fard’ and ‘Somali’ banana cultivars stored at 5, 13, and 22 °C for 21 d Experiments include digital image analysis of fractal dimension (FD), grayscale (Igray), bruise susceptibility (BS), color, surface area (AS), and some other physical attributes like weight loss %, peel thickness reduction %, and firmness. …”
Get full text

Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury by Eric Cortada, Jun Yao, Yu Xia, Friederike Dündar, Paul Zumbo, Boris Yang, Alfonso Rubio-Navarro, Björn Perder, Miaoyan Qiu, Anthony M. Pettinato, Edwin A. Homan, Lisa Stoll, Doron Betel, Jingli Cao, James C. Lo

“…Abstract The immune system coordinates the response to cardiac injury and controls regenerative and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation associated with heart failure. …”
Get full text

Behavioral Biases in Investor Decision-Making: A Comparative Meta-Analysis of Behavioral Finance Research by Seyed Amir Sabet, Saeed Aibaghi esfahani, Abdolmajid Abdolbaghi Ataabadi

“…The consistency of findings across domestic and international studies underscores how fundamental behavioral biases are to financial decision-making processes.…”
Get full text

The role of mindfulness training supported by virtual reality in the nonpharmacological treatment of schizophrenia-research design by Andrzej Cechnicki, Adrian Chrobak, Iga Plencler, Przemysław Stankiewicz, Aneta Kalisz, Piotr Błądziński, Dawid Kruk, Stanisław Radoń, Bernadetta Szewczyk, Agata Faron-Górecka, Michał Korostyński, Marcin Siwek

“…The study protocol, designed according to the Oxford Quality Assessment System, outlines a randomized controlled trial (RCT) evaluating a novel Virtual Reality-based Mindfulness Skills Training (VR-MST) versus standard, non-VR MST in patients with schizophrenia (SZ). …”
Get full text

oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21 by Thomas Nickel, Susanne Pfeiler, Claudia Summo, Reinhard Kopp, Georgios Meimarakis, Zeljka Sicic, Marius Lambert, Korbinian Lackermair, Robert David, Andres Beiras-Fernandez, Ingo Kaczmarek, Michael Weis

“…CCL21- and CCR7-mRNA levels were significantly downregulated in atherosclerotic plaques versus non-atherosclerotic controls [90% for CCL21 and 81% for CCR7 (𝑃<0.01)]. …”
Get full text

Intercountry and intracountry variations in opinions of palliative care specialist physicians in Germany, Italy, Japan and UK about continuous use of sedatives: an international cr... by Guido Miccinesi, Lenzo Robijn, Nigel Sykes, Lalit Krishna, Takuya Kawahara, Carsten Klein, Madelon T Heijltjes

“…Also, the proportion of physicians who agreed versus disagreed with the statement that CUS may not alleviate suffering adequately even in unresponsive patients, was approximately equal. …”
Get full text

Use of an anatomical atlas in real-time EIT reconstructions of ventilation and pulsatile perfusion in preterm infants by Christopher J. Rocheleau, Trevor D. Overton, Nilton Barbosa da Rosa, Gary J. Saulnier, Omid Rajabi Shishvan, Christopher D. Baker, Katelyn G. Enzer, Jennifer L. Mueller

“…EIT parameters describing homogeneity of ventilation distribution throughout the lung and the distribution anterior/posterior and in the left versus right lung were computed for each infant. The left/right ventilation distribution was found to distinguish between the healthy and the preterm infants with statistical significance (p-value< 0.05). …”
Get full text

Establishment and Comparison of Juvenile Female Mouse Models of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis by Lishan Zhou, Deliang Liu, Zhiwei Wang, Hui Dong, Xiaohu Xu, Shunchang Zhou

“…The aim of this study was to present a direct comparison of the maternal versus postweaning female juvenile NAFLD and nonalcoholic steatohepatitis (NASH) animal models. …”
Get full text

Mathematical Modeling of <i>Salmonella</i> Inactivation During Apple Drying and Pre-Drying Heating in Closed Environments by Ren Yang, Shuang Zhang, Juming Tang

“…There is now an urgent need to understand the influence of process conditions on the thermal inactivation of pathogens in various drying operations. …”
Get full text