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Evidence of differences in diurnal electrodermal, temperature and heart rate patterns by mental health status in free-living data
Published 2025-08-01“…Most strikingly, differences in EDA between those with high versus low symptoms were most prominent during the early morning. …”
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503
N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis
Published 2025-01-01“…Methods Quantitative untargeted mass spectrometric proteomic and lipidomic analyses were conducted to examine changes in protein and lipid abundance in wild-type (WT) versus N88S seipin-expressing mutant cells. Differentially expressed proteins were categorized into functional networks to highlight altered protein functions and signaling pathways. …”
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504
Melanoma Vaccines: Comparing Novel Adjuvant Treatments in High-Risk Patients
Published 2025-06-01“…Key differences between the two trials include the use of CPIs, with 100% of patients in the mRNA trial receiving pembrolizumab versus 37% of the patients in the TL trial receiving either an anti-PD-1 or anti-CTLA-4. …”
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505
Behavioral Biases in Investor Decision-Making: A Comparative Meta-Analysis of Behavioral Finance Research
Published 2025-12-01“…The consistency of findings across domestic and international studies underscores how fundamental behavioral biases are to financial decision-making processes.…”
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506
Toward a marginal Arctic sea ice cover: changes to freezing, melting and dynamics
Published 2025-06-01“…Our analysis shows that a different balance of processes controls the volume budget of the MIZ versus the pack ice. …”
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507
The effects of dietary supplementation with red grape pomace treated with ozone gas on ruminal fermentation activities, nutrient digestibility, lactational performance, and blood m...
Published 2024-12-01“…The digestibility coefficients of the DM and the NDF increased (P < 0.001) in diets containing RGP versus the control, but not for the crude protein and ether extract. …”
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508
Révision de l’espèce Homo erectus (Dubois, 1893)
Published 2000-06-01“…Concerning the rigorous use of index, arguments on the rules which are to be adopted are still published (Atchley et al., 1976; Atchley et Anderson, 1978 versus Albrecht, 1978; Dodson, 1978; Hills, 1978). …”
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End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence
Published 2025-01-01“…Then, the pipeline subsequently incorporates a classification module to categorize the effective connectivity (directed graphs) of brain networks of patients versus matched healthy control. The graph convolutional architecture is also compared to legacy methods such as random forest and support vector machine providing a complete benchmark. …”
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The influence of “Efial” medicine on the chondrocytes functional state
Published 2014-12-01“…Adding the medicine at concentrations from 70 µg/ml to 1.5 µg/ml in a nutrient medium at plating and the on 3-rd cultivation day resulted in a reduction of glycosaminoglycans (GAG) and collagen type II content compared to the control (without medicine). Using the test medicine at concentrations from 0.15 µg/ml to 1.5 ng/ml caused the increase of GAG by 17.1±2.3 % (in conditions of adding at seeding) and by 19.4±2.5 (in conditions of adding on 3-rd cultivation day), and the increase in collagen type II content in the chondrocyte culture by 10.3±1.7 % (in conditions of adding on 3-rd cultivation day) and without effect in conditions of adding when seeding (0.1-1.7 x105 cells) versus the control. …”
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Machine Learning-Driven Transcriptome Analysis of Keratoconus for Predictive Biomarker Identification
Published 2025-04-01“…<b>Methods:</b> We analyzed the GSE77938 (PRJNA312169) dataset for differential gene expression (DGE) and performed gene set enrichment analysis (GSEA) using Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways to identify enriched pathways in keratoconus (KTCN) versus controls. Machine learning algorithms were then used to analyze the gene sets, with SHapley Additive exPlanations (SHAP) applied to assess the contribution of key feature genes in the model’s predictions. …”
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512
Increasing robustness of in vitro assay for immnosuppressive effect of mesenchymal stromal/stem cells: The role of inflammatory cytokine production by peripheral blood mononuclear...
Published 2025-03-01“…Conclusions: To make robust the MSC immunosuppressive potency assay system, controlling the quality of PBMCs used for the assay is essential. …”
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Probiotic potential of Phocaeicola coprocola in modulating learning and memory behaviors in the honeybee model
Published 2025-06-01“…Gut microbial composition was analyzed using full-length 16S rRNA gene sequencing based on PacBio SMRT technology, and metabolic profiling was conducted using untargeted LC–MS/MS analysis.ResultsP. coprocola supplementation significantly improved cognitive performance, with learning success rates of 74.13% in the treatment group versus 50.85% in controls (p = 0.0093). This intervention also led to increased gut diversity (Shannon index, p = 0.0079). …”
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Effect of short PSG peptide fragments on the cytokine profile in Wistar rats during allogeneic transplantation <i>in vivo</i>
Published 2022-07-01“…We used an original model of host-versus-graft response in male Wistar rats transplanted with bone marrow, without prior conditioning treatment of recipients. …”
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Human bodies in virtual worlds: a systematic review of implicit sense of agency and ownership measured in immersive virtual reality environments
Published 2025-08-01“…., temporal or spatial misalignment between actions and outcomes) and movement control (e.g., replacing user actions with pre-recorded movements). …”
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TDP-43 pathology is associated with divergent protein profiles in ALS brain and spinal cord
Published 2025-08-01“…In the cortex mitochondrial membrane/envelope and ion transmembrane transport pathways were enriched in the detergent-insoluble fraction. RNA/DNA metabolic processes (in spinal cord) versus mitochondrial and synaptic protein pathways (in cortex) were upregulated in the detergent-soluble fraction of ALS cases and downregulated in the insoluble protein fraction. …”
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Features of Bone Mineral Density, Calcium-Phosphorus Metabolism and Bone Remodeling in Patients with Systemic Lupus Erythematosus
Published 2024-06-01“…The mean value of osteocalcin in woman with SLE was significantly lower than in CG and control (11.81 ± 0.49 ng/ml versus 18.61 ± 0.75 ng/ml and 19.28 ± 1.88, p < 0.001). …”
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Epilepsy is associated with the accelerated aging of brain activity in sleep
Published 2024-11-01“…Subanalyses were conducted on a subset with NIH Toolbox cognitive testing for total, fluid, and crystallized composite cognition.Results138 patients with epilepsy (32 exclusively focal and 106 generalizable [focal seizures with secondary generalization]) underwent in-patient monitoring, and age-matched, non-epilepsy controls were analyzed. The mean BAI was higher in epilepsy patients vs controls and differed by epilepsy type: −0.05 years (controls) versus 5.02 years (all epilepsy, p < 0.001), 5.53 years (generalizable, p < 0.001), and 3.34 years (focal, p = 0.03). …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT
Published 2024-12-01“…Methods The feasibility randomised control trial involved 13 sites across two counties in England. …”
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