Human Retinal Organoid Model of Ocular Toxoplasmosis by Liam M. Ashander, Grace E. Lidgerwood, Amanda L. Lumsden, João M. Furtado, Alice Pébay, Justine R. Smith

“…This progression was accompanied by changes in the levels of selected tachyzoite transcripts—<i>SAG1</i>, <i>GRA6</i>, and <i>ROP16</i>—and human cytokine transcripts—<i>CCL2</i>, <i>CXCL8</i>, <i>CXCL10</i>, and <i>IL6</i>—in infected versus control conditions. Our human retinal organoid model of ocular toxoplasmosis offers the opportunity for many future lines of study, including tachyzoite interactions with retinal cell populations and leukocyte subsets, parasite stage progression, and disease processes of different <i>T. gondii</i> strains, as well as drug testing.…”
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Neurophysiological Markers of Design-Induced Cognitive Changes: A Feasibility Study with Consumer-Grade Mobile EEG by Nathalie Gerner, David Pickerle, Yvonne Höller, Arnulf Hartl

“…Twenty participants completed two crossover sessions in an office-like setting with nature-inspired versus urban-inspired design elements. Each session included controlled phases of focused on-screen cognitive task and off-screen breaks. …”
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Bertolotti's syndrome in low-backache population: Classification and imaging findings by Reddy Ravikanth, Pooja Majumdar

“…Dysplastic transverse processes were classified according to the Castellvi radiographic classification system. …”
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Transforming Growth Factor β1 and Myocardial Remodeling in Patients with Chronic Heart Failure of Ischemic Genesis by N. E. Zakirova, A. N. Zakirova, D. F. Nizamova

“…The intensity of myocardial remodeling and fibrosis processes in patients with a progressive course of CHF is related to ТФР-β1 hyperexpression and is associated with a high level of activity of natriuretic peptides.…”
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The biosensor using the target urine volatile organic compounds for detecting diabetic kidney disease by Chatchai Kreepala, Vichayut Suthat Na Ayutaya, Rungrueang Phatthanakun, Kittipong Thabsuwan, Jirayupa Paewponsong

“…Our results demonstrated that hydrogen and ethanol VOCs, measured at a minimum electrical resistance threshold of 4500 mV, effectively distinguished DKD from NS and other control groups. The mean differences in electrical resistance among DKD versus normal, DM without DKD, and NS were 868.3, 145.5, and 881.2 ohms, respectively (p < 0.05). …”
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Strategies for Enhancing Students' Mathematical Reasoning and Disposition Ability in a Freedom Curriculum by Getut Pramesti, Enny Pardjijanti, Arofah Adzarori Nugraha

“…The study focuses on grade IX students at a public senior high school in Surakarta, Indonesia. The control group is class Phase E-8, which follows a direct learning approach and is known as the Non-CORE class. …”
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Collective behavior quantification on human odor effects against female Aedes aegypti mosquitoes-Open source development. by Abdul Halim Poh, Mahmoud Moghavvemi, Cherng Shii Leong, Yee Ling Lau, Alireza Safdari Ghandari, Alexlee Apau, Faisal Rafiq Mahamd Adikan

“…The setup is demonstrated by testing a simple response of mosquitoes in the presence of human odor versus control, one session with continuous human presence as a stimuli and the other with periodic presence. …”
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Collaborative Search Algorithm for Multi-UAVs Under Interference Conditions: A Multi-Agent Deep Reinforcement Learning Approach by Wei Wang, Yong Chen, Yu Zhang, Yong Chen, Yihang Du

“…However, in the presence of interference, communication disruptions between UAVs and ground control stations can severely degrade coordination efficiency, leading to prolonged search times and reduced mission success rates. …”
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Somatosensory Plasticity in Pediatric Cerebral Palsy following Constraint-Induced Movement Therapy by Pawel J. Matusz, Alexandra P. Key, Shirley Gogliotti, Jennifer Pearson, Megan L. Auld, Micah M. Murray, Nathalie L. Maitre

“…Before and directly after the treatment, we recorded their cortical event-related potential (ERP) responses to calibrated light touch (versus a control stimulus) at the more and less affected hand. …”
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Dysbiosis of gut and urinary microbiota in urolithiasis patients and post-surgical cases by Yuanyuan Jia, Meng Han, Haoyu Ge, Jie Qiao, Ruyan Chen, Chenyu Li, Cailin Liu, Lei Fang, Yanhao Shen, Saiqi Qi, Yuli Wang, Xiaobing Guo

“…We conducted 16S rRNA sequencing analysis to evaluate the variations in microbial communities among these groups during urinary stone production and therapy processes.ResultsIn fecal microbiota, alpha diversity was lower in the stone group versus the control group, with the postoperative group showing the lowest diversity. …”
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Third-Generation Fatty Emulsions as Part of Parenteral Feeding in Operated Cancer Patients by S. V. Lomidze, I. V. Nekhayev, A. V. Sytov, I. A., Klimanov, N. B. Borovkova, S. V. Yefimenko, I. S. Korotkov, A. A. Severin

“…In the study group, the serum anti-inflammatory activity of IL-4 was more evident than that in the control group and the proinflammatory activity (IL-6 concentration) decreased, which can support that as compared with the second-generation fatty emulsions, third-generation ones with a balanced omega 3 to omega-6 fatty acid ratio (1:2.7) had a normalizing effect on systemic inflammatory processes and cytokine balance with increased anti-inflammatory and reduced proinflammatory activities. …”
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Reviewing the ecological evidence base for management of emerging tropical zoonoses: Kyasanur Forest Disease in India as a case study. by Sarah J Burthe, Stefanie M Schäfer, Festus A Asaaga, Natrajan Balakrishnan, Mohammed Mudasssar Chanda, Narayanaswamy Darshan, Subhash L Hoti, Shivani K Kiran, Tanya Seshadri, Prashanth N Srinivas, Abi T Vanak, Bethan V Purse

“…Options may include "ecological interventions" that target vectors or hosts and require good knowledge of underlying transmission processes, which may be more effective, economical, and long lasting than conventional approaches. …”
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Strategies for recruitment of adolescent girls into physical activity programmes: a systematic review protocol [version 2; peer review: 2 approved] by Tanya O'Brien, Emer M Barrett, Catherine D Darker, David Mockler

“…Background Physical activity is essential for youth physical and mental health, yet just 15% of adolescent girls versus 22% of adolescent boys worldwide meet the World Health Organization guideline of at least an average of 60 minutes of moderate-to-vigorous physical activity per day. …”
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Strategies for recruitment of adolescent girls into physical activity programmes: a systematic review protocol [version 1; peer review: 2 approved] by Tanya O'Brien, Emer M Barrett, Catherine D Darker, David Mockler

“…Background Physical activity is essential for youth physical and mental health, yet just 15% of adolescent girls versus 22% of adolescent boys worldwide meet the World Health Organization guideline of 60 minutes of moderate-to-vigorous physical activity per day. …”
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Primipaternity in multiparas as a predominant high risk factor for preeclampsia over prolonged birth intervals: A study of 33,000 singleton pregnancies in Reunion Island. by Pierre-Yves Robillard, Silvia Iacobelli, Simon Lorrain, Francesco Bonsante, Malik Boukerrou, Marco Scioscia, Phuong Lien Tran, Gustaaf Dekker

“…<h4>Objectives</h4>To evaluate the relative importance of changing paternity ("primipaternity", direct inquiry with patients) in multiparas versus prolonged birth/pregnancy interval as risk factors for preeclampsia (PE) by a logistic regression model comparing the adjusted odds ratios of both exposures.…”
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Identifying predictors of response to oral non-steroidal anti-inflammatory drugs and paracetamol in osteoarthritis: a hypothesis-driven protocol for an OA Trial Bank individual par... by Michael Doherty, Jie Wei, Yilin Xiong, Marienke van Middelkoop, Weiya Zhang, Monica S M Persson

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Strategies for recruitment of adolescent girls into physical activity programmes: a systematic review protocol [version 3; peer review: 3 approved] by Tanya O'Brien, Emer M Barrett, Catherine D Darker, David Mockler

“…Background Physical activity is essential for youth physical and mental health, yet just 15% of adolescent girls versus 22% of adolescent boys worldwide meet the World Health Organization guideline of at least an average of 60 minutes of moderate-to-vigorous physical activity per day. …”
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Comprehensive proteomic profiling of intestinal tissues in patients with ulcerative colitis by Huiling Wang, Qi Xie, Yi Xie, Weiguang Luo

“…This study aimed to investigate the proteomic differences in the intestinal tissues of patients with UC and healthy individuals using high-throughput liquid chromatography–tandem mass spectrometry (LC–MS/MS) and bioinformatics methods.MethodsThe study employed a comprehensive proteomic analysis using LC–MS/MS to identify protein expression differences in intestinal tissues from five patients with UC versus five healthy controls. Subsequent bioinformatics analyses, including Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, elucidated altered biological processes.ResultsWe identified 194 upregulated and 323 downregulated proteins in the tissues of patients with UC, indicating a significant difference in protein expression. …”
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Invited perspectives: Integrating hydrologic information into the next generation of landslide early warning systems by B. B. Mirus, B. B. Mirus, T. Bogaard, R. Greco, M. Stähli

“…Given the increasing number of studies across the globe using hydrologic monitoring, mathematical modeling, or both in combination, it is now possible to make some insights into the advantages versus limitations of this approach. The extensive progress demonstrates the value of in situ hydrologic information for reducing both failed and false alarms through the ability to characterize infiltration during – as well as the drainage and drying processes between – major storm events. …”
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Demonstration of the presence of the "deleted" MIR122 gene in HepG2 cells. by Ibrahim A Y Hamad, Yue Fei, Anastasia Z Kalea, Dan Yin, Andrew J P Smith, Jutta Palmen, Steve E Humphries, Philippa J Talmud, Ann P Walker

“…MicroRNA 122 (miR-122) is highly expressed in the liver where it influences diverse biological processes and pathways, including hepatitis C virus replication and metabolism of iron and cholesterol. …”
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