Machine learning for predicting antimicrobial resistance in critical and high-priority pathogens: A systematic review considering antimicrobial susceptibility tests in real-world h... by Carlos M Ardila, Daniel González-Arroyave, Sergio Tobón

“…However, limitations such as retrospective methodology for model development, nonstandard data processing, and lack of validation in randomized controlled trials must be considered before applying these models in clinical practice.…”
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Noradrenergic deficits contribute to apathy in Parkinson's disease through the precision of expected outcomes. by Frank H Hezemans, Noham Wolpe, Claire O'Callaghan, Rong Ye, Catarina Rua, P Simon Jones, Alexander G Murley, Negin Holland, Ralf Regenthal, Kamen A Tsvetanov, Roger A Barker, Caroline H Williams-Gray, Trevor W Robbins, Luca Passamonti, James B Rowe

“…More broadly, these results reconcile emerging predictive processing accounts of the role of noradrenaline in goal-directed behaviour with the clinical symptom of apathy and its potential pharmacological treatment.…”
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CCR2 restricts IFN-γ production by hippocampal CD8 TRM cells that impair learning and memory during recovery from WNV encephalitis by Shenjian Ai, Artem Arutyunov, Joshua Liu, Jeremy D. Hill, Xiaoping Jiang, Robyn S. Klein

“…Using CCR2-deficient mice, we determined that CCR2 expression is not essential for CNS T cell recruitment or virologic control during acute WNV infection. However, transcriptomic analyses of forebrain CCR2+ versus CCR2− CD8 TRM during WNV recovery reveal that CCR2 signaling significantly regulates hippocampal CD8 TRM phenotype and function via extrinsic and intrinsic effects, limiting expression of CD103, granzyme A and IFN-γ, respectively, and increasing the percentages of virus-specific CD8 T cells. …”
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The Effects of Ultra-High Pressure Combined with Egg White Protein on the Gel Physical Properties of Reduced-Salt Shrimp Surimi by Yefan Wang, Zisheng Zhai, Xinchi Yu, Deyang Li

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An investigation of plasma cell-free RNA for the detection of colorectal cancer: From transcriptome marker selection to targeted validation. by Emmalee J Northrop-Albrecht, Chung Wah Wu, Calise K Berger, William R Taylor, Patrick H Foote, Karen A Doering, Anna M Gonser, Aditya Bhagwate, Zhifu Sun, Douglas W Mahoney, Kelli N Burger, Lisa A Boardman, John B Kisiel

“…There were 895 exons that were differentially expressed (325 upregulated, 570 downregulated) among cancers versus controls. In phases 2 and 3, fewer markers were validated than expected in independent sets of patients, most of which were from previously published literature (FGA, FGB, GPR107, CDH3, and RP23AP7). …”
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Genetic effects on molecular network states explain complex traits by Matthias Weith, Jan Großbach, Mathieu Clement‐Ziza, Ludovic Gillet, María Rodríguez‐López, Samuel Marguerat, Christopher T Workman, Paola Picotti, Jürg Bähler, Ruedi Aebersold, Andreas Beyer

“…Genetic variants affecting this PT state globally shifted the molecular network along a single‐dimensional axis, thereby modulating processes including energy and amino acid metabolism, transcription, translation, cell cycle control, and cellular stress response. …”
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An Integrated Analysis of Transcriptomic and Metabolomic Effects Reveals Insights into Stress Responses in Largemouth Bass (<i>Micropterus salmoides</i>) Under MS-222 (Tricaine Met... by Ping Gao, Rimeng Chen, Deyun Ma, Shanshan Lin, Haodong Yu, Xuezhen Zhang

“…Methods: Experimental groups exposed to 40 mg/L MS-222 for 12 h were compared with untreated controls, and then transcriptomic and metabolomic analyses were performed on gill and liver samples. …”
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Investigation of heavy metal contamination in doogh distributed in Shahrekord by Hadiseh Baharlou, Maryam Abbasvali, مجتبی Boniadian

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An approach to measuring language-specific brain function in developmental language disorder by Caroline Larson, Jason C. Crutcher, Hannah R. Thomas, Michael C. Stevens

“…Methods and results: The adaptive semantic matching paradigm involved word-similarity judgements (e.g., age-night) and perceptual-similarity judgements of symbol strings (e.g., τουχφ-τουχε; i.e., control condition) during fMRI scanning. The adaptive component involved increases or decreases in task difficulty depending on in-the-moment individual participant accuracy (2-up-1-down adaptive weighted staircase, converges >80 % accuracy); controlling for individual variability in task performance. …”
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Early-life cognitively stimulating activities and late-life cognitive function in the St. Louis Baby Tooth Later Life Health Study by Andrea L. Roberts, Xinye Qiu, Kaleigh A. McAlaine, Laura T. Germine, Ran S. Rotem, Marc G. Weisskopf

“…Six tasks measured overall cognitive function, processing speed, visual short-term memory, attention, cognitive control, episodic memory, working memory, perception, vocabulary, and verbal reasoning. …”
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Potato Protein Concentrate: Improving Quality Using a More Effective and Sustainable Method by Thomas Wilbur Davis, Ecevit Yilmaz, William R. Newson

“…However, the most effective phenolic-binding resin resulted in a lower PPC yield versus control. In contrast, WAX 003 showed moderate phenolic removal but resulted in a higher yield (60 ± 0.69% to 90.1 ± 0.1% of control), demonstrating a trade-off between phenolic reduction and PPC recovery. …”
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Neuroimaging Correlates of Post-COVID-19 Symptoms: A Functional MRI Approach by Marine M. Tanashyan, Polina I. Kuznetsova, Sofya N. Morozova, Vladislav A. Annushkin, Anton A. Raskurazhev

“…Task fMRI data were processed using the SPM12 software package based on MATLAB R2022a. …”
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Determination of Main Bearing Dynamic Clearance in a Shield Tunneling Machine Through a Broadband PMUT Array with a Decreased Blind Area and High Accuracy by Guoxi Luo, Haoyu Zhang, Delai Liu, Wenyan Li, Min Li, Zhikang Li, Lin Sun, Ping Yang, Ryutaro Maeda, Libo Zhao

“…In addition, a specific ultrasound signal processing circuit with functions of transmitting, receiving, and processing ultrasonic waves was developed. …”
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High‐Intensity Interval Training Mitigates Sarcopenia and Suppresses the Myoblast Senescence Regulator EEF1E1 by Yaoshan Dun, Wenliang Zhang, Yang Du, Kangling Xie, Yuan Liu, Cui Li, Ling Qiu, Siqian Fu, Thomas P. Olson, Yuqiong Long, Baiyang You, Suixin Liu

“…Methods We conducted a randomized crossover trial to evaluate plasma proteomic reactions to acute HIIT (four 4‐min high‐intensity intervals at 70% maximal capacity alternating with 4 min at 30%) versus MICT (constant 50% maximal capacity) in inactive adults. …”
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Statins for primary prevention of cardiovascular events in people with HIV: target trial and modelling study by Sarah R Haile, Oliver Senn, Nicola Serra, Eva A Rehfuess, Milo A Puhan, Mona Loutfy, Jennifer E Thorne, Greer A Burkholder, Michael J Silverberg, Raynell Lang, Timothy R Sterling, Vincent C Marconi, Huldrych F Günthard, Sally B Coburn, Gregory M Lucas, Henock G Yebyo, Oliver Langselius, Jonathan A Colasanti, Sonia Napravnik, Maile Karris, Keri N Althoff

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Assessing the impact of deep‐learning assistance on the histopathological diagnosis of serous tubal intraepithelial carcinoma (STIC) in fallopian tubes by Joep MA Bogaerts, Miranda P Steenbeek, John‐Melle Bokhorst, Majke HD vanBommel, Luca Abete, Francesca Addante, Mariel Brinkhuis, Alicja Chrzan, Fleur Cordier, Mojgan Devouassoux‐Shisheboran, Juan Fernández‐Pérez, Anna Fischer, C Blake Gilks, Angela Guerriero, Marta Jaconi, Tony G Kleijn, Loes Kooreman, Spencer Martin, Jakob Milla, Nadine Narducci, Chara Ntala, Vinita Parkash, Christophe dePauw, Joseph T Rabban, Lucia Rijstenberg, Robert Rottscholl, Annette Staebler, Koen Van de Vijver, Gian Franco Zannoni, Monica vanZanten, AI‐STIC Study Group, Joanne A deHullu, Michiel Simons, Jeroen AWM van derLaak

“…The level of certainty that the participants felt versus their own assessment also significantly increased, by 0.24 on a 10‐point scale (p < 0.01). …”
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Changes in runoff from major alpine watersheds on the Qinghai-Tibetan plateau: A review by Guohui Li, Zongxing Li, Baoqing Zhang, Zongjie Li

“…This study systematically evaluates: (1) shifts in runoff recharge mechanisms under climate warming, (2) the relative contributions of precipitation, groundwater, and cryospheric meltwater to runoff generation, and (3) the differential impacts of climate change versus anthropogenic activities on hydrological processes. …”
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Vergence Eye Movements: From Basic Science to Clinical Application by Wolfgang Jaschinski, Rudolf Groner

“…Human vision under natural conditions involves both eyes in coordination controlled by interacting processes subsumed under the concept of vergence.. …”
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Eye movements of children with and without developmental dyslexia in an alphabetic script during alphabetic and logographic tasks by Susanne Trauzettel-Klosinski, Theda Faisst, Vera Schick, Giulia Righetti, Christoph Braun, Angelika Cordey-Henke, Ching-Chu Sun, Stephan Kuester-Gruber

“…Abstract Eye movements (EM) during naming alphabetic versus logographic stimuli in children with and without developmental dyslexia (DD) were examined for each stimulus separately to identify conspicuous characteristics that influence naming performance. 40 children (group DD = 18; control group C = 22) were taught Chinese characters. …”
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Crotonylation deficiency of S100A7 K49 promotes psoriatic keratinocyte proliferation through enhanced interaction with RAGE by Huifang Liang, Ying Wang, Junqin Li, Kaiming Zhang

“…To investigate the profile of lysine crotonylation and its pathogenic role in psoriasis, we conducted a comparative analysis of crotonylation-modified proteins in psoriatic lesions versus healthy controls. Mutant keratinocytes with crotonylation deficiency of S100A7 were generated to explore its functional effects in psoriasis. …”
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