Locus coeruleus tonic upregulation increases selectivity to inconspicuous auditory information in autistic compared to non-autistic individuals: a combined pupillometry and electro... by Nico Bast, Jumana Ahmad, Luke Mason, Emily J. H. Jones, Magdalena Matyjek, Leonie Polzer, Christina Luckhardt, Anna Katharina Müller, Grainne M. McAlonan, Tobias Banaschewski, Sarah Baumeister, Eva Loth, Christine M. Freitag, The EU-AIMS LEAP group consists of

“…A more negative MMN-amp to standards was associated with a higher SEPR to standards. Controlling for these associations, autistic versus non-autistic individuals showed a higher SEPR in response to standards. …”
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Hypoxic cancer-associated fibroblast exosomal circSTAT3 drives triple negative breast cancer stemness via miR-671-5p/NOTCH1 signaling by Lu Yang, Siyuan Zhao, Xu Liu, Yuchen Zhang, Shaorong Zhao, Xuan Fang, Jin Zhang

“…Clinical validation used BC tissues (n = 60) and plasma exosomes from BC patients (n = 40) versus healthy controls (n = 25). Results Hypoxic CAF-derived exosomes efficiently transferred circSTAT3 to TNBC cells, promoting proliferation, migration, EMT, and stemness marker expression. …”
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In vitro assessment of the effect of free amino acids on ruminal fermentation and 15N enrichment of ruminal nitrogen pools by S.E. Räisänen, C.V. Almeida, X. Zhu, L.F. Martins, A. Richards, D. Wasson, A.N. Hristov

“…For statistical analysis, the individual AA treatments were grouped and analyzed by set of incubations: EAA1 (incubations 1 and 2), EAA2 and NEAA (incubations 3 and 4) versus Amicase and AS. Additionally, responses to Amicase and individual AA treatments were compared expressed as the percent difference from AS (negative control). …”
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On Colour, Category Effects, and Alzheimer’s Disease: A Critical Review of Studies and Further Longitudinal Evidence by F. Javier Moreno-Martínez, Inmaculada C. Rodríguez-Rojo

“…We examined whether colour benefits the ability of Alzheimer’s disease (AD) patients and normal controls (NC) when naming items differing in colour diagnosticity: living things (LT) versus nonliving things (NLT). …”
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High-resolution 3D spatial distribution of complex microbial colonies revealed by mass spectrometry imaging by Yuting Shen, Yisu Wang, Jianing Wang, Peisi Xie, Chengyi Xie, Yanyan Chen, Niaz Banaei, Kangning Ren, Zongwei Cai

“…Additionally, we investigated metabolite spatiotemporal dynamics in multiple colonies, observing changes over time and distinct patterns in single versus merged colonies. These findings shed light on the repel-merge process for multi-colony formation. …”
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Prognostic value of miR-106a and miR-20a in AML patients with chemotherapy or allo-HSCT treatment by Yue Liu, Jiayu Liu, Yuehua Feng, Xiaoguang Xu, Yingjie Miao, Huijuan Chen, Yu Zhou, Yijun Pan, Yan Liu, Weiying Gu, Yang Cao

“…GSEA and PPI were constructed using ClusterProfiler and STRING database.Results: MiR-106a and miR-20a elevated in AML versus healthy controls. In chemotherapy group, miR-106ahigh or miR-20ahigh predicted poor OS and EFS, with dual-high expression conferring the worst outcome. …”
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Are the Largest Benefits of Kilometer‐Scale Climate Models Over Mountains or Over Flatland? by Basile Poujol, Junhong Lee, Thomas Rackow, Mathias W. Rotach, Nikolina Ban

“…Abstract Climate and weather simulations are challenging in mountainous regions, due to complex meteorological processes. While a kilometer‐scale grid spacing significantly improves the representation of topography, little is known about the associated added value over mountains. …”
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Driving factors of aerosol acidity: a new hierarchical quantitative analysis framework and its application in Changzhou, China by X. Duan, X. Duan, G. Zheng, C. Chen, Q. Zhang, K. He

“…Aerosol pH shows large temporal variations, while the driving factors of chemical profiles versus meteorological conditions are not fully understood due to their intrinsic complexity. …”
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Understanding patient pathways to Mother and Baby Units: a longitudinal retrospective service evaluation in the UK by Nikolina Jovanović, Žan Lep, Giles Berrisford, Aysegul Dirik, Julia Barber, Bukola Kelani, Olivia Protti

“…Electronic records were accessed to extract data on the type of admission, the referral process and the type of pathway (simple or complex). …”
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Impact of Biochar Aging on Soil Physicochemical Properties by Tamara Apostolović, Arthur Gross, Álvaro Fernando García Rodríguez, José María de la Rosa, Bruno Glaser, Heike Knicker, Snežana Maletić

“…Biochar undergoes significant transformations in soil as a result of chemical, physical, and biological processes. These alterations can impact its initial properties, influencing both its agronomic effectiveness and its capacity for carbon sequestration. …”
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Effect of desflurane, sevoflurane or propofol on the incidence of postoperative delirium in older adults undergoing moderate- to high-risk major non-cardiac surgery: study protocol... by Mario Kofler, Barbara Sinner, Alexandra Graf, Edith Fleischmann, Susanne Trübsbach, Christian Reiterer, Barbara Kabon, Alexander Taschner, Nikolas Adamowitsch, Melanie Fraunschiel, Katharina Horvath, Nicole Hantakova, Simon Schallmeiner, Christine Eckhardt, Beatrix Hochreiter, Oliver Zotti, David Emler, Kira Margarete Hörl, Helena Langthaler, Magdalena List, Barbara Rossi, Mathias Stiefsohn, Giulia Zanvettor, Florian Wolfgang Zenz, Iris Emshoff, Christoph Geiger, Nicole Innerhofer, Sasa Rajsic, Beatrix Reyer, Melanie Widmann

“…Therefore, we will evaluate the effect of desflurane versus sevoflurane versus propofol for the maintenance of anaesthesia on the incidence of postoperative delirium in older adults undergoing moderate- to high-risk major non-cardiac surgery. …”
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Spectrophotometric Studies on the Thermodynamics of the ds-DNA Interaction with Irinotecan for a Better Understanding of Anticancer Drug-DNA Interactions by Reza Hajian, Tan Guan Huat

“…The Kb at a low concentration of salt is dominated by electrostatic interaction (98.5%) while that at a high concentration of salt is weakly controlled by nonelectrostatic processes (19.0%). A moderate stabilization of the double helix ds-DNA occurs when CPT-11 binds to ds-DNA as indicated by the increase in Tm of ct-DNA by approximately 15°C in the presence of CPT-11. …”
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Cognitive and Functional Impairment in Stroke Survivors with Basilar Artery Occlusive Disease by Kenia Repiso Campanholo, Adriana Bastos Conforto, Carolina Medeiros Rimkus, Eliane Correa Miotto

“…The aims of this study were (1) to compare the cognitive statuses of BAOD survivors versus healthy controls and (2) to correlate the functional capacity outcomes with the cognitive profiles of BAOD patients. …”
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Chromatin measurements reveal contributions of synthesis and decay to steady‐state mRNA levels by Sylvia C Tippmann, Robert Ivanek, Dimos Gaidatzis, Anne Schöler, Leslie Hoerner, Erik van Nimwegen, Peter F Stadler, Michael B Stadler, Dirk Schübeler

“…Abstract Messenger RNA levels in eukaryotes are controlled by multiple consecutive regulatory processes, which can be classified into two layers: primary transcriptional regulation at the chromosomal level and secondary, co‐ and post‐transcriptional regulation of the mRNA. …”
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The Creation of Artificial Data for Training a Neural Network Using the Example of a Conveyor Production Line for Flooring by Alexey Zaripov, Roman Kulshin, Anatoly Sidorov

“…As a tool-platform solution, the concept of digital twins for simulating technological processes was considered, within which synthetic data is utilized. …”
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Sensitivity Analysis of the Thermal Structure Within Subduction Zones Using Reduced‐Order Modeling by Gabrielle M. Hobson, Dave A. May

“…Using the ROMs, we can efficiently investigate the sensitivity of temperature to input parameters, physical processes, and modeling choices. We find that temperature, and by extension the potential rupture extent, is most sensitive to variability in parameters that describe shear heating on the slab interface, followed by parameters controlling the thermal structure of the incoming lithosphere and coupling between the slab and the mantle. …”
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Vector Autoregressive Hierarchical Hidden Markov Models for Extracting Finger Movements Using Multichannel Surface EMG Signals by Nebojša Malešević, Dimitrije Marković, Gunter Kanitz, Marco Controzzi, Christian Cipriani, Christian Antfolk

“…The effectiveness of the novel algorithms was assessed versus methods commonly used for real-time classification of EMGs in a prosthesis control application. …”
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Domain acquisition enabled functional expansion of the TFIIS transcription factor family by Kateryna Matveyeva, Ainhoa Sánchez de Diego, María Ángeles García-López, Julio Gutiérrez, Thierry Fischer, Karel H.M. van Wely

“…In metazoans, the architecture has evolved additional extensions to act on downstream RNA processing. Here, we argue in favor of a single protein superfamily encompassing TFIIS, BYE1, and their metazoan homologs. …”
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A lightweight intelligent compression method for fast Sea Level Anomaly data transmission. by Xiaodong Ma, Xiang Wan, Lei Zhang, Dong Wang, Zeyuan Dai

“…Generalization tests reveal controlled performance degradation: PSNR reduced by 4.2 ± 0.3 dB, SSIM by 0.7126, and Iden by 4.1%, confirming robustness under marine operational scenarios. …”
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Experiences with the privatization of home care: evidence from Denmark by Barbara Fersch, Per H Jensen

“…We have identified four areas of tensions: 1) those between liberal and libertarian ideas and values versus local political orientations and practices; 2) new tensions and lines of demarcation among political actors, where old political conflicts no longer holds; 3) tensions between promises and actual delivery, due to insufficient control of private contractors; and 4) those between market principles and the professional ethics of care providers.…”
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