Multiparametric performance comparison of dental composites for clear aligner attachments by Yunlin Guan, Jiarong Xu, Junhong Qiu, Hao Cai, Wenxuan Xia, Zhou Ye, Ting Sang

“…Conclusions Z250 underperformed in color stability, SBS, and durability versus Z350/P60, though demonstrated cost-effectiveness. …”
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The Efficacy of Conversational AI in Rectifying the Theory-of-Mind and Autonomy Biases: Comparative Analysis by Marcin Rządeczka, Anna Sterna, Julia Stolińska, Paulina Kaczyńska, Marcin Moskalewicz

“…ObjectiveThis study aimed to assess the effectiveness of therapeutic chatbots (Wysa and Youper) versus general-purpose language models (GPT-3.5, GPT-4, and Gemini Pro) in identifying and rectifying cognitive biases and recognizing affect in user interactions. …”
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Immunological profiling in type 2 diabetes mellitus and type 2 diabetic kidney disease: insights from single-cell LacNAc sequencing by Mengyun Xiao, Zigan Xu, Xiaohui Zhu, Jing Chen, Ru Wang, Yaxuan Wang, Xiang Gao, Shaodong Luan, Xiaoyan Pu

“…However, the underlying mechanism remains unclear.MethodsWe employed single-cell LacNAc sequencing (scLacNAc-seq) to characterize immune cell populations, glycosylation patterns, and functional alterations in peripheral blood mononuclear cells (PBMCs), focusing on low-density granulocytes (LDGs), from patients with T2DM and T2DKD versus healthy controls (HC). In vitro cultures of primary human neutrophils under high glucose and high glucose plus serum from patients with T2DKD were used to assess NET formation via myeloperoxidase (MPO) detection. …”
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Interneuron transcriptomics reveals pathologic markers of Alzheimer's disease progression by Kevin S. Chen, Mohamed H. Noureldein, Diana M. Rigan, John M. Hayes, Kyle J. Loi, Junguk Hur, Masha G. Savelieff, Eva L. Feldman

“…To reveal underlying mediators, we spatially profiled the transcriptome of neuronal subtypes in 5XFAD versus control mice at early- and late-stage disease. …”
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Computerized cognitive training in cognitively healthy older adults: a systematic review and meta-analysis of effect modifiers. by Amit Lampit, Harry Hallock, Michael Valenzuela

“…The overall effect size (Hedges' g, random effects model) for CCT versus control was small and statistically significant, g = 0.22 (95% CI 0.15 to 0.29). …”
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Elevated Expression of <i>TGFB1</i> in PBMCs Is Associated with Intracranial Aneurysm Formation, but <i>TGFB3</i> Expression Implicated Rupture by Kinga Sutkowska, Olga Martyna Koper-Lenkiewicz, Marta Żebrowska-Nawrocka, Marta Jakoniuk, Tomasz Łysoń, Marzena Tylicka, Ewa Balcerczak, Joanna Matowicka-Karna, Joanna Kamińska

“…<b>Introduction:</b> The transforming growth factor beta (TGF-β) signaling pathway plays a critical role in cellular processes, including maintaining vascular integrity and regulating vascular remodeling. …”
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Impaired splicing machinery in craniopharyngiomas unveils PRPF8 and RAVER1 as novel biomarkers and therapeutic targets by Antonio C. Fuentes-Fayos, Miguel E. G-García, Teresa Sánchez-Medianero, John Apps, Álvaro Flores-Martínez, Ana S. De la Rosa-Herencia, Ignacio Gil-Duque, Georg Otto, Eva Venegas-Moreno, Eugenio Cárdenas Ruiz-Valdepeñas, Aura D. Herrera-Martínez, Juan Solivera, Manuel D. Gahete, David A. Cano, Rosa Ortega, Alfonso Soto-Moreno, María A. Gálvez-Moreno, Juan Pedro Martínez-Barberá, Raúl M. Luque

“…Here, we uncover a profound dysregulation in the expression of relevant spliceosome-components and splicing-factors in craniopharyngiomas versus control non-tumour tissues, identifying PRPF8 and RAVER1 as key tumour suppressor factors associated with relevant oncogenic processes. …”
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What is the most relevant soil structure parameter to describe field-measured N2O emissions? by Emile Maillet, Agnès Grossel, Isabelle Cousin, Laurent Arbaret, Lionel Cottenot, Marine Lacoste

“…Nevertheless, the gas transfer parameters can be easily measured over a short period of time, whereas the soil structure indicators determined from 3D images require an acquisition and a processing phase that can be time consuming. A good compromise to evaluate the field N2O flux potential from an easy measure would be to evaluate the relative gas diffusivity, which directly controls the diffusion of oxygen in soil and thereby the microbial processes of N2O production.…”
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Eggshell Quality Traits and Transcriptome Gene Screening Between Yunnong and Jingfen Chicken Breeds by Zijian Li, Hao Wu, Jing Fu, Maida Mushtaq, Muhammad Khan, Yong Liu, Zobia Azeem, Hongmei Shi, Yang He, Ru Zhang, Muhammad Aziz Ur Rahman, Jiajia Kang, Changrong Ge, Kun Wang

“…This study aimed to compare eggshell quality traits and identify genetic markers in YN chickens versus commercial Jingfen chickens (JF). A total of 400 chicks (200 per breed) were reared for 300 days under controlled conditions. …”
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Repurposing losartan potassium against rheumatoid arthritis via transdermally-delivered leciplexes: Accentuated efficacy through modulation of angiotensin II/AT1R/AT2R axis by Amira A. Hussein, Basmah N. Aldosari, Randa M. Zaki, Obaid Afzal, Adel A. Ali, Heba M. Aboud, Yasmin M. Ahmed, Demiana M. Naguib

“…To accomplish this objective, LST-LPX dispersions were assembled through a single-step process and optimized via D-optimal design for various physicochemical traits employing Design-Expert® software. …”
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Compost and Biochar to Promote Soil Biological Activities under Sweet Potatoes Cultivation in a Subtropical Semiarid Region by Josabeth Navarro, Jahdiel Salazar, James Jihoon Kang, Jason Parsons, Chu-Lin Cheng, Alexandria Castillo, Engil Isadora Pujol Pereira

“…Sweet potato was cultivated during summer 2018 in McAllen, Texas, under control (no fertilizer), NPK (synthetic fertilizer), RC (yard-waste compost), and AC (compost produced under an enhanced composting process), and biochar (gasified walnut shell at 900°C), each with three replicates. …”
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Support and Assessment for Fall Emergency Referrals (SAFER 1): cluster randomised trial of computerised clinical decision support for paramedics. by Helen Anne Snooks, Ben Carter, Jeremy Dale, Theresa Foster, Ioan Humphreys, Philippa Anne Logan, Ronan Anthony Lyons, Suzanne Margaret Mason, Ceri James Phillips, Antonio Sanchez, Mushtaq Wani, Alan Watkins, Bridget Elizabeth Wells, Richard Whitfield, Ian Trevor Russell

“…Non-significant differences between groups included: subsequent emergency contacts (34.6% versus 29.1%; OR 1.27, 95% CI 0.93 to 1.72); quality of life (mean SF12 differences: MCS -0.74, 95% CI -2.83 to +1.28; PCS -0.13, 95% CI -1.65 to +1.39) and non-conveyance (42.0% versus 36.7%; OR 1.13, 95% CI 0.84 to 1.52). …”
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DIRECT EFFECT OF RED LASER IRRADIATION ON TESTICULAR AND EPIDIDYMIS TISSUE FUNCTION IN MALE RABBITS

“…The histological sample was taken after necropsy method of all experimental animals for preparation slide processes to examine under a light microscope. The result of the experiment showed histological changes induced by exposure the animals to red laser (650nm-10w) which present as versus changes and these pathological changes are directly fit with period of exposure which appears as degeneration, oedematous, hyperemia and necrosis into testicular and epididymis.…”
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Composition Medium Comparability in a Direct Writing Assessment of Non-Native English Speakers by Edward W. Wolfe, Jonathan R. Manalo

“…This study sought to determine whether performance on a direct writing assessment is comparable for examinees when given the choice to compose essays in handwriting versus word processing. We examined this relationship controlling for English language proficiency and several demographic characteristics of examinees using linear models. …”
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Understanding episodic memory dynamics: Retrieval and updating mechanisms revealed by fMRI and tDCS by Dong-ni Pan, CuiZhu Lin, Ma Xin, Oliver T. Wolf, Gui Xue, Xuebing Li

“…Interference trials elicited heightened activation in the Inferior Parietal Lobe (IPL), Dorsolateral Prefrontal Cortex (DLPFC), and Dorsal Anterior Cingulate Gyrus (dACC) versus no-retrieval controls, and increased frontoparietal and Occipital Fusiform Gyrus (OFG) activation versus relearning. …”
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Effect of a structured Orem’s self-care model nursing intervention on sleep quality and academic self-efficacy in nursing students by Mir Amirhossein Seyednazari, Kourosh Amini, Farhad Ramezani-Badr, Abdolah Khorami Markani

“…Results The results showed that before the intervention, there was no statistically significant difference in the average total sleep quality score (7.64 ± 2.48 in the experimental group versus 7.42 ± 2.74 in the control group) or academic self-efficacy (148.38 ± 12.10 in the experimental group versus 144.66 ± 10 in the control group) between the two groups. …”
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How mindfulness-based training improves stress-related health: a selective review of randomized clinical trials comparing psychological mechanisms of action by Lara M. C. Puhlmann, Lara M. C. Puhlmann, Lara M. C. Puhlmann, Veronika Engert, Veronika Engert, Veronika Engert

“…Most MBIs rely on training programs that simultaneously target multiple and distinct mental processes, hampering mechanistic conclusions. Addressing this shortcoming, the present selective review provides an overview of randomized controlled trials (RCTs) that directly contrast the effects of distinct components of mindfulness on stress-related health. …”
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The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells by Friederike Behler-Janbeck, Anke Baranowsky, Timur A. Yorgan, Michelle Y. Jaeckstein, Anna Worthmann, Marceline M. Fuh, Karthikeyan Gunasekaran, Gisa Tiegs, Michael Amling, Thorsten Schinke, Joerg Heeren

“…Overall, these data indicate that acetate regulates bone architecture via SCFA-Gpr41/43 signaling by modulating the osteogenic versus adipogenic differentiation of mesenchymal stem cells.…”
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Design of 20-deoxyingenol-esters-based PKC agonists and their lysosome biogenesis-enhancing activity by Jia-Jia Wan, Qiu-Yuan Yin, Mao Sun, Cui-Shan Zhang, Hao-Jing Zang, Pei-Tong Yao, Ming-Rui Yuan, Ding-Kang Chen, Feng Guo, Qun Chen, Bo-Wen Ouyang, Zi-Fei Xu, Ming-Ming Cao, Chong-Lin Yang, Xiao-Jiang Hao, Ying-Tong Di

“…At 20 μM, these derivatives enhanced autophagic flux by 2.45-fold and 2.31-fold versus vehicle control. Moreover, compounds 4 and 18 exhibited a dose-dependent increase in lysosome numbers, promoted TFEB nuclear translocation, and enhanced lysosome-mediated lipid droplet clearance. …”
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Clinical Features of Juvenile Open-angle Glaucoma by A. V. Malyshev, A. S. Apostolova, A. A. Sergienko, A. F. Teshev, G. Yu. Karapetov, M. K. Ashhamahova, B. N. Hatsukova

“…JOAG patients were younger than the control group — 30.1 ± 1.5 and 37.0 ± 1.9 years, p = 0.007, there were 58 % men versus 42 % women. …”
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