Cross-species single-cell RNA-seq analysis reveals disparate and conserved cardiac and extracardiac inflammatory responses upon heart injury by Eric Cortada, Jun Yao, Yu Xia, Friederike Dündar, Paul Zumbo, Boris Yang, Alfonso Rubio-Navarro, Björn Perder, Miaoyan Qiu, Anthony M. Pettinato, Edwin A. Homan, Lisa Stoll, Doron Betel, Jingli Cao, James C. Lo

“…Abstract The immune system coordinates the response to cardiac injury and controls regenerative and fibrotic scar outcomes in the heart and subsequent chronic low-grade inflammation associated with heart failure. …”
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The role of mindfulness training supported by virtual reality in the nonpharmacological treatment of schizophrenia-research design by Andrzej Cechnicki, Adrian Chrobak, Iga Plencler, Przemysław Stankiewicz, Aneta Kalisz, Piotr Błądziński, Dawid Kruk, Stanisław Radoń, Bernadetta Szewczyk, Agata Faron-Górecka, Michał Korostyński, Marcin Siwek

“…The study protocol, designed according to the Oxford Quality Assessment System, outlines a randomized controlled trial (RCT) evaluating a novel Virtual Reality-based Mindfulness Skills Training (VR-MST) versus standard, non-VR MST in patients with schizophrenia (SZ). …”
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oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21 by Thomas Nickel, Susanne Pfeiler, Claudia Summo, Reinhard Kopp, Georgios Meimarakis, Zeljka Sicic, Marius Lambert, Korbinian Lackermair, Robert David, Andres Beiras-Fernandez, Ingo Kaczmarek, Michael Weis

“…CCL21- and CCR7-mRNA levels were significantly downregulated in atherosclerotic plaques versus non-atherosclerotic controls [90% for CCL21 and 81% for CCR7 (𝑃<0.01)]. …”
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Intercountry and intracountry variations in opinions of palliative care specialist physicians in Germany, Italy, Japan and UK about continuous use of sedatives: an international cr... by Guido Miccinesi, Lenzo Robijn, Nigel Sykes, Lalit Krishna, Takuya Kawahara, Carsten Klein, Madelon T Heijltjes

“…Also, the proportion of physicians who agreed versus disagreed with the statement that CUS may not alleviate suffering adequately even in unresponsive patients, was approximately equal. …”
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Machine vision system combined with multiple regression for damage and quality detection of bananas during storage by Mai Al-Dairi, Pankaj B. Pathare, Rashid Al-Yahyai, Nasser Al-Habsi, Hemanatha Jayasuriya, Zahir Al-Attabi

“…The study used a machine vision system and applied image process analysis to assess the bruise parameters of the damage zone and external quality attributes of 18 treatments generated from bruised (30 cm and 60 cm drop heights) and non-bruised (control) ‘Fard’ and ‘Somali’ banana cultivars stored at 5, 13, and 22 °C for 21 d Experiments include digital image analysis of fractal dimension (FD), grayscale (Igray), bruise susceptibility (BS), color, surface area (AS), and some other physical attributes like weight loss %, peel thickness reduction %, and firmness. …”
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Establishment and Comparison of Juvenile Female Mouse Models of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis by Lishan Zhou, Deliang Liu, Zhiwei Wang, Hui Dong, Xiaohu Xu, Shunchang Zhou

“…The aim of this study was to present a direct comparison of the maternal versus postweaning female juvenile NAFLD and nonalcoholic steatohepatitis (NASH) animal models. …”
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Mathematical Modeling of <i>Salmonella</i> Inactivation During Apple Drying and Pre-Drying Heating in Closed Environments by Ren Yang, Shuang Zhang, Juming Tang

“…There is now an urgent need to understand the influence of process conditions on the thermal inactivation of pathogens in various drying operations. …”
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DYNAMICS OF CHANGES IN THE ELECTROMYOGRAPHIC INDICATORS OF MASTICATING MUSCLES DURING THE PROSTHETIC REHABILITATION OF PATIENTS WITH PATHOLOGICAL ABRASION OF TEETH WHEN USING REMOV... by H.M. Balia, V.S. Kuz, O.V. Shemetov, I.M. Martynenko, I.O. Kuz

“… Pathological abrasion of teeth is a fast process, accompanied by changes in the dental tissues and tissues of periodontium, as well as a disorder of the functions of the masticatory muscles and TMJ (temporomandibular joint). …”
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Cognitive mechanisms of mindfulness-based pain management in chronic pain by Emily Mohr, Sophie Matthew, Lipika Narisetti, Colin Duff, Poppy Schoenberg

“…Since aberrations in cognitive executive functioning are apparent in chronic pain and corroborate with higher pain severity and poorer clinical outcomes, we conducted a two-part mechanistic clinical study that aimed to examine; (1) cognitive performance deficits measured during neurophysiology tasks, in chronic pain patients versus healthy controls; and (2) a mechanistic trial into whether Mindfulness-Based Pain Management/MBPM modulates cognitive functioning, and its interplay with clinical symptoms, in chronic pain patients versus a treatment-as-usual/TAU matched patient control. …”
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Tuning Frontiers of Efficiency in Tissue P Systems with Evolutional Communication Rules by David Orellana-Martín, Luis Valencia-Cabrera, Bosheng Song, Linqiang Pan, Mario J. Pérez-Jiménez

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Echo Intima-Media Thickness (IMT) in the Evaluation of Early Atherosclerosis in Inflammatory Bowel Disease (IBD) Patients – a Prospective Study by Ana Maria NEGREANU, Simona BADIU, Eugenia PANAITESCU, Monica IONITA, Lucian NEGREANU

“…Conclusions: In our study we found an increased echo IMT in IBD patients versus control, but the values did not reach statistical significance. …”
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Continuous Skin Rejuvenation by Combining Nonablative Fractional Laser With Daily Application of a Multibeneficial Composition Formulation: A Blinded Randomized Clinical Trial Stud... by Xinxuan Zhang, Manru Ning, Mengqing Lin, Qi Tang, Yihuai Liang, Feifei Wang, Xiaoke Xu

“…ABSTRACT Background and Aims Skin aging is a common concern among individuals, and laser treatments are recognized as one of the most effective approaches to mitigate the aging process. The study aims to compare a multibeneficial formula serum versus a blank formulation in achieving maximum efficacy following a single treatment of nonablative fractional laser for facial skin rejuvenation. …”
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Interactive Effect of Residue Quality and Agroecologies Modulate Soil C- and N-Cycling Enzyme Activities, Microbial Gene Abundance, and Metabolic Quotient by Birhanu Agumas, Getachew Agegnehu, Tesfaye Feyisa

“…Leucine-aminopeptidases and TLP were identified as rate-limiting factors for protein and peptide decomposition, while β-xylosidase controlled hemicellulose degradation. In summary, this study provides insights into the intricate relationships between agroecology, residue quality, enzymatic activities, and microbial communities, shedding light on key processes governing soil ecological functions.…”
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Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by V. V. Moroz, V. T. Dolgikh, S. A. Karpitskaya

“…Neuropsychological testing revealed postoperative cognitive dysfunction on standard therapy which included impaired attention and concentration, executive function, memory, speech, visual constructional skills, abstract thinking, counting, and orientation (21 points on the MoCA scale versus 28–30 points for normal). We found that the pathogenetic factors of cognitive dysfunction included insufficient antioxidant protection, decreased TNF-α and elevated interleukin-18 levels along with an increased level of C-reactive protein in plasma, which manifested as activation of free-radical oxidation processes and reduced antioxidant system and performance of nonspecific resistance. …”
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Urolithiasis complicated by chronic obstructive pyelonephritis in patients with concomitant diseases of the cardiovascular system by R. V. Royuk, S. K. Yarovoy, R. A. Khomov

“…Exacerbations of ChOP in patients of group I developed 1.5 times more often (once in 2.8-3 years) than in patients from the control group (on average after 18 months versus 28), and in group II almost annually (1 time in 13 months). …”
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Evaluation of Ocular and Systemic Oxidative Stress Markers in Patients with Diabetic Retinopathy by Ana Karen López-Contreras, Diana Esperanza Arévalo-Simental, Fermín Paúl Pacheco-Moisés, María Guadalupe Martínez-Ruíz, Cecilia Olvera-Montaño, Ricardo Raúl Robles-Rivera, Sonia Sifuentes-Franco, Tannia Isabel Campos-Bayardo, Selene Guadalupe Huerta-Olvera, Adolfo Daniel Rodríguez-Carrizalez

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TPM4 overexpression drives colon epithelial cell tumorigenesis by suppressing differentiation and promoting proliferation by Rajsumeet S. Macwan, Giulio Ferrero, Barbara Pardini, Alessio Naccarati, Piotr B. Kozlowski, Michael J. Papetti

“…We hypothesize that aberrant expression of genes involved in the crypt-luminal migration of colon epithelial cells, a process necessary for their growth arrest and maturation, may disrupt differentiation and transition cells from a normal to tumorigenic state. …”
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Adequate post-ischemic reperfusion of the mouse brain requires endothelial NFAT5 by Reiner Kunze, Paul Wacker, Paula Breuer, Emil Nasyrov, Ivan M. Kur, Andreas Weigert, Andreas H. Wagner, Hugo H. Marti, Thomas Korff

“…In contrast, MCAO-induced edema formation, inflammatory processes and angiogenesis were not altered in Nfat5 (EC)−/− mice. …”
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Comparison of maternal and neonatal outcomes of midwifery-led care with routine midwifery care: a retrospective cohort study by Shirin Shahbazi Sighaldeh, Elaheh Eskandari, Shahla Khosravi, Elham Ebrahimi, Shima Haghani, Fatemeh Shateranni

“…Abstract Introduction Globally, the management of low-risk pregnancies by midwives often leads to a more natural childbirth process, which enhances physical and psychological outcomes for mothers and their babies. …”
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Predicting deformation kinetics and fractures propagation in coal-rock masses using acoustic emission testing by Majid Khan, Xueqiu He, Dazhao Song, Zhenlei Li, Xianghui Tian

“…Using the micro-crack density criterion and 3D-crack growth theory, changes in above parameters verified the cracks transformation process. These findings showed that, the proposed approach compared with the conventional approaches, can improve disaster control and management plans, predict critical failures, and save lives in global mining projects when applied to field-scale studies.…”
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