Efficacy and safety of HYYK formula for residual follicle revival in premature ovarian insufficiency: a multicenter, randomized, double-blind, placebo-controlled trial protocol by Yin Peng, Jian Liu, Yang Li, Guangning Nie, Fangping Cheng, Daning Feng, Qiaolin Du, Jian Huang, Hongyan Yang

“…Conventional hormone replacement therapy (HRT) alleviates symptoms but fails to restore ovarian function. …”
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Radiological and clinical outcomes of combined wedge versus lateral closing wedge high tibial osteotomy for medial osteoarthritis of the knee: a randomized controlled trial by Maarten R. Huizinga, A. J. de Vries, T. M. van Raaij, R. W. Brouwer

“…Conclusions In this randomized controlled trial CW and LCW give similar accuracy of correction. …”
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Interactive Computer-Adaptive Chronic Kidney Disease (I-C-CKD) Education for Hospitalized African American Patients: Protocol for a Randomized Controlled Trial by Akilah King, Tayo Omoniyi, Lindsay Zasadzinski, Cynthia Gaspard, Denesha Gorman, Milda Saunders

“…This includes 50 patients in the control group and 46 patients in the intervention group. …”
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Effect of testosterone treatment during puberty in boys with Klinefelter syndrome (The TIPY Study): protocol for a nationwide randomised, double-blinded, placebo-controlled study by Gary Butler, Anders Juul, Judith L Ross, Jørgen Holm Petersen, Kurt Kristensen, Ann-Margrethe Rønholt Christensen, Ida Dyhr Caspersen, Andrés Felipe Østergaard Fritzbøger, Niels Birkebæk, Anders Jørgen Schou, Shanlee Davis, Sophie van Rijn, Lise Aksglaede

“…Currently, testosterone replacement therapy (TRT) in adolescence is considered the first-line treatment by some physicians for patients with KS and biochemical signs of hypogonadism. …”
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Dynamic Modeling of Multi-category Jointing for the Autonomous-railRapid Tram and Real Vehicle Validation by HUANG Ruipeng, YUAN Xiwen, HU Yunqing, ZHANG Xinrui, ZHANG Sha, LI Xiaoguang

“…Autonomous-rail rapid tram replaces traditional steel wheels with rubber tires, and uses machine vision to track the central virtual track line to control vehicle motion. …”
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Grid Forming Converters for Low Inertia Systems<bold>-</bold>Capabilities and Limitations: A Critical Review by Qusay Salem, Bayan Bany Fawaz, Rafat Aljarrah, Mazaher Karimi

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Positioning Technology Without Ground Control Points for Spaceborne Synthetic Aperture Radar Images Using Rational Polynomial Coefficient Model Considering Atmospheric Delay by Doudou Hu, Chunquan Cheng, Shucheng Yang, Chengxi Hu

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Quadrature-Phase-Locked-Loop-Based Back-Electromotive Force Observer for Sensorless Brushless DC Motor Drive Control in Solar-Powered Electric Vehicles by Biswajit Saha, Aryadip Sen, Bhim Singh, Kumar Mahtani, José A. Sánchez-Fernández

“…This work presents a sensorless brushless DC motor (BLDCM) drive control, optimized for solar photovoltaic (PV)- and battery-fed light electric vehicles (LEVs). …”
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Hybrid Efficient Fast Charging Strategy for WPT Systems: Memetic-Optimized Control with Pulsed/Multi-Stage Current Modes and Neural Network SOC Estimation by Marouane El Ancary, Abdellah Lassioui, Hassan El Fadil, Yassine El Asri, Anwar Hasni, Abdelhafid Yahya, Mohammed Chiheb

“…A neural-network-based state of charge (SOC) estimator provides accurate real-time monitoring, complemented by MA-tuned PI control for enhanced resonance stability and adaptive pulsed current–MCM profiles for the optimal energy transfer. …”
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Safety of bioinductive bovine collagen implants for arthroscopic rotator cuff repair by Hideki Kinjo, MD, Naoki Suenaga, MD, PhD, Naomi Oizumi, MD, PhD, Kotaro Nishida, MD, PhD

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Impact of decreasing the proportion of higher energy foods and reducing portion sizes on food purchased in worksite cafeterias: A stepped-wedge randomised controlled trial. by James P Reynolds, Minna Ventsel, Daina Kosīte, Brier Rigby Dames, Laura Brocklebank, Sarah Masterton, Emily Pechey, Mark Pilling, Rachel Pechey, Gareth J Hollands, Theresa M Marteau

“…<h4>Methods and findings</h4>This stepped-wedge randomised controlled trial (RCT) evaluated 2 interventions: (i) availability: replacing higher energy products with lower energy products; and (ii) size: reducing the portion size of higher energy products. …”
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The effects of instability core training on balance ability and paddling performance among young male Chinese flatwater sprint kayakers: a randomized controlled trial by Jianxin Gao, Zhigang Gong, Shamsulariffin Samsudin, Borhannudin Bin Abdullah, Roxana Dev Omar Dev

“…Method A randomized controlled trial (RCT) recruited 63 eligible kayakers aged 16–19 years from the Nanchang Yao Lake kayaking training base in Jiangxi province, China. …”
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Wake-up timer and binary exponential backoff for ZigBee-based wireless sensor network for flexible movement control system of a self-lifting scaffold by Hua Liang, Guangxiang Yang, Ye Xu, Iqbal Gondal, Chao Wu

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Comparison of utilizing a hypertonic saline solution and mannitol to improve brain relaxation during craniotomy in patients with brain tumours: a prospective randomized controlled... by Cattleya Thongrong, Worapoom Tangphikunatam, Pornthep Kasemsiri, Pichayen Duangthongphon, Amnat Kitkhuandee, Narin Plailaharn, Apinya Kittiponghansa, Darunee Sripadungkul, Monsicha Somjit, Lumyai Sabangban, Thirada Jimarsa

“…Researchers conducted a prospective, double-blind, randomized controlled trial. Sixty-six patients with supratentorial or posterior fossa brain tumours undergoing craniotomy were randomized into two groups. …”
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Effects of chronic low-frequency pulsed magnetic fields exposure on the contractility and morphology of biceps brachii in healthy adults–a randomized controlled, double-blind trial... by Zhongshan Li, Zhongshan Li, Wenhao Li, Shi Bai, Tieli Yang

“…However, from the analysis of the change trends, the PEMF group showed a downward trend, while the control group showed an increasing trend. In the PEMF group, all four parameters of muscle morphology were significantly higher than pre-test, while in the control group, all but one of the muscle stiffness metrics were significantly lower. …”
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Efficacy of shared decision making in tobacco cessation among health facilities of Haryana, India – A double blinded, parallel group Randomized Controlled trial Protocol by Pranav Kshtriya, Sonu Goel, Abhishek Ghosh

“…Methods: 1) Design: a two-arm parallel group randomized controlled trial (RCT) 2) Setting: Three selected government health centers of Haryana, India. 3) Participants: 596 tobacco users aged ≥18 visiting the outpatient department/Tobacco cessation centers (TCC) of selected health centers. 4) Intervention and Comparator: The intervention group will receive shared decision process for prescribing pharmacotherapy (Nicotine replacement therapy, Bupropion) using specially designed decision aid based on three-talk model for tobacco cessation, while the control group will get standard care. 5) Measurements: Primary outcomes include urinary cotinine analysis for evaluating 7-day point prevalence abstinence. …”
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Altered co-expression patterns of synovial fluid proteins related to the immune system and extracellular matrix organization in late stage OA, compared to non-OA controls by Jenny Lönsjö, Martin Rydén, Aleksandra Turkiewicz, Velocity Hughes, Jon Tjörnstand, Patrik Önnerfjord, Martin Englund, Neserin Ali

“…ObjectiveSynovial fluid contains proteins that may have been released from surrounding tissues, our aim was to gain new insights into the proteomic profiles of human synovial fluid in knees with and without osteoarthritis (OA).MethodsWe used synovial fluid from 11 patients with end-stage medial compartment knee OA, aspirated during total knee replacement, and from 13 deceased donors who had no prior history of knee OA (healthy controls). …”
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Randomised controlled trial comparing hydroxyapatite coated uncemented hemiarthroplasty with cemented hemiarthroplasty for the treatment of displaced intracapsular hip fractures: a... by Nicholas Parsons, Matthew L Costa, Juul Achten, Melina Dritsaki, Robin Gillmore Lerner, Alwin McGibbon, Miguel Antonio Fernandez, Katy Mironov, May E Png, Jenny Gould, Xavier Griffin

“…The most common type of hip fracture (displaced intracapsular) is treated for the majority of patients with a partial hip replacement (hemiarthroplasty). The hemiarthroplasty implant can be fixed to the bone with or without bone cement. …”
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Evaluating the Impact of Pharmacotherapy in Augmenting Quit Rates Among Hispanic Adults in an App-Delivered Smoking Cessation Intervention: Secondary Analysis of a Randomized Contr... by Margarita Santiago-Torres, Kristin E Mull, Brianna M Sullivan, Ana Paula Cupertino, Ramzi G Salloum, Matthew Triplette, Michael J Zvolensky, Jonathan B Bricker

“…We then examined whether the use of any pharmacotherapy (ie, nicotine replacement therapy [NRT], varenicline, or bupropion) and NRT alone augmented each app-based intervention efficacy. …”
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Genicular nerve radiofrequency ablation, phenol neurolysis or conservative medical management in patients with knee osteoarthritis: protocol for the RADIOPHENOL randomised controll... by Markus W Hollmann, Johan Haumann, Bram Thiel, Marc B Godfried, Jan-Willem Kallewaard, Paul R de Wit, Rienk van Beek, Monique Schokker, Carin Wensing, Gezina Oei, Derk A van Kampen, Lars Elzinga, Gijs Hendriks, Jeroen van de Heiden, Jan Willem Coumou

“…The RADIOPHENOL study investigates if denervation of knee sensory (genicular) nerves can serve the gap between conservative and invasive treatment for younger patients and for patients who cannot undergo joint replacement surgery due to comorbid health conditions.Methods and analysis The RADIOPHENOL study is a multicentre unblinded randomised controlled trial with three parallel arms (1:1:1). …”
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