Controlled field study investigating effects of 2 methods of enriching moderate-quality maternal colostrum on transfer of passive immunity and well-being of neonatal dairy calves by W.A. Knauer, M.A. Brown, E.M. Oosterheert, R. Schell, A. Geiger, S.M. Godden

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Evaluation of the SAMe-TT2R2 score to predict the quality of anticoagulation control in patients after mitral valve replacement by Yilin Li, Yang Gao, Qiuming Hu, Xu Meng, Shubin Li

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The effect of prehabilitation for older patients awaiting total hip replacement. A randomized controlled trial with long-term follow up by Odd-Einar Svinøy, Jakob Vangen Nordbø, Are Hugo Pripp, May Arna Risberg, Astrid Bergland, Pål Oliver Borgen, Gunvor Hilde

“…Methods In a two-armed randomized controlled trial we recruited 98 participants aged 70 years or older with a Harris Hip Score less than 60 awaiting elective primary total hip replacement. …”
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Norsesquiterpenes from <i>Lolium perenne</i> and Their Replacement Control of an Invasive Plant, <i>Ageratina adenophora</i>, Through Allelopathy by Wenbo Shi, Tong An, Xiaomin Yang, Youlin Li, Amanula Yimingniyazi, Zhixiang Liu, Yulong Feng

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Prevention Of Breast and Endometrial cancer using Total Diet Replacement (PROBE-TDR) trial: protocol for a randomised controlled trial by Robert Clarke, Emma J Crosbie, Basil G Issa, John Belcher, Helen Clarke, Anthony Howell, Michelle Harvie, Hannah Harrison, Cheryl Lombardelli, Suzanne Krizak, Katharine Sellers, Yit Y Lim, Caroline Parkin, Shruthi Patel, Anthony J Maxwell, Julie Wisely, Sacha J Howell

“…This study aims to examine the cellular and molecular changes in breast and endometrial tissue in high-risk women following TDR-induced weight loss, as well as longer-term adherence to a 12-month TDR weight loss intervention.Methods and analysis PROBE-TDR (PRevention Of Breast and Endometrial cancer using Total Diet Replacement) is a prospective, non-blinded, randomised controlled trial of 47 women at increased risk of breast and/or endometrial cancer. …”
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Selection of timing of continuous renal replacement therapy in patients with acute kidney injury: A meta-analysis of randomized controlled trials. by Jiawei Qi, Wenwen Wu, Jingzhu Wang, Xin Guo, Chengyun Xia

“…Consequently, we aimed to assess the impact of continuous renal replacement therapy (CRRT) initiation on the outcomes of patients with AKI. …”
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Perioperative metformin use in patients undergoing total joint replacement surgery: protocol for a randomised, placebo-controlled pilot study by Aidan Morrell, Steven Shelofsky, Hannah Hoffman, Cole McCallister, Thomas W Huff, Kathryn L Schabel, Avital Y O’Glasser, Ryland P Kagan

“…Although correction of hyperglycaemia has been shown to improve patient outcomes, there is a lack of consensus regarding optimal perioperative glucose management after total joint replacement surgery. This pilot study aims to assess the feasibility of performing a multicentre randomised controlled trial to investigate the effect of perioperative metformin use on glycaemic control in the setting of total joint arthroplasty.Methods and analysis This blinded, placebo-controlled, pilot randomised controlled trial will enrol 40 participants aged 18–99 years undergoing total hip or knee arthroplasty at a single academic tertiary centre. …”
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Effectiveness of Tranexamic Acid to Prevent Blood Loss in Patients Undergoing Hip Arthroplasty: A Randomised Controlled Study by Arun Karthik Ravichandran, Rajavel Kalirajan, Gowthaman NaNambiraj, Sabari Vaasan Lakshmi Kanthan, Madhan Raju, Tathagath Tiwary, Saravanan Ravi, Aravindhan Krishnasamy Yuvaraj

“…Results: In the present study, 69 of the 138 individuals received TXA in the interventional group, while 69 received a placebo in the control group. The mean±Standard Deviation (SD) age was 44.6±17.6 years in the interventional group and 48.5±16.4 years in the control group. …”
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The Role of Correcting Structural and Functional Albumin Properties in Ascites Control in Decompensated Cirrhotic Patients by A. A. Turkina, M. V. Maevskaya, M. S. Zharkova, V. T. Ivashkin

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Analysis of factors associated with the initiation of renal replacement therapy in patients on veno-arterial extracorporeal membrane oxygenation: a case–control study by Michel Perez-Garzon, Ana Castillo-Castillo, Maria Ferro-Peñuela, Claudia Poveda-Henao, Mario Mercado-Diaz, Henry Robayo-Amortegui

“…Methods A retrospective case–control study that included patients who received VA-ECMO and were admitted to the intensive care unit between 2019 and 2023. …”
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Nanosurgery and Bioengineered Regenerative Protocols for the Treatment of Hip Osteoarthritis: A Double-Blind Randomized Controlled Trial as an Alternative to Surgical Hip Replacement by Cezary Wasilczyk, Bartosz Wasilczyk

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High-dose glucocorticoid treatment vs. glucocorticoid replacement in immune checkpoint inhibitor associated hypophysitis (CORTICI): an open, randomised controlled trial by Verena Theiler-Schwetz, Christian Trummer, Lisa Schmitt, Angelika Terbuch, Barbara Obermayer-Pietsch, Erika Richtig, Stefan Pilz

“…This is the first randomised study to evaluate whether hormonal recovery differs in patients treated with high-dose glucocorticoids versus glucocorticoid replacement therapy.Design/Methods In this single-centre, open, randomised controlled study, patients with ICI associated hypophysitis were randomised 1:1 to high-dose glucocorticoid treatment (1 mg/kg of prednisolone for two weeks, followed by tapering until week 7 and a switch to hydrocortisone 20 mg total daily dose in week 8) or glucocorticoid replacement therapy (hydrocortisone 20 mg total daily dose) over 8 weeks. …”
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Evaluation of the therapeutic effect of estrogen replacement therapy combined with autologous serum therapy in controlling severe dry eye disease in perimenopausal women by Tao Li, Juan Tang, Xiao Wang, Zhiwu Lin, Changfen Li, Guogang Liu, Guibao Xiao

“…Abstract To explore the therapeutic effect of estrogen replacement therapy combined with autologous serum therapy in controlling severe dry eye disease in perimenopausal women. …”
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REST: a preoperative tailored sleep intervention for patients undergoing total knee replacement – feasibility study for a randomised controlled trial by Simon White, Rachael Gooberman-Hill, Emma Johnson, Joel Glynn, Vikki Wylde, Chris Penfold, Katie Whale, Nicholas Howells, Ashley Blom, Amanda Burston, Wendy Bertram, Dane Rayment

“…Objectives To test the feasibility of a randomised controlled trial (RCT) of a novel preoperative tailored sleep intervention for patients undergoing total knee replacement.Design Feasibility two-arm two-centre RCT using 1:1 randomisation with an embedded qualitative study.Setting Two National Health Service (NHS) secondary care hospitals in England and Wales.Participants Preoperative adult patients identified from total knee replacement waiting lists with disturbed sleep, defined as a score of 0–28 on the Sleep Condition Indicator questionnaire.Intervention The REST intervention is a preoperative tailored sleep assessment and behavioural intervention package delivered by an Extended Scope Practitioner (ESP), with a follow-up phone call 4 weeks postintervention. …”
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Efficacy of virtual reality-based rehabilitation following total knee replacement: a systematic review and meta-analysis of randomized control trials by Afaf A. M. Shaheen, Maha F. Algabbani, Manar M. Alshahrani, Fatimah A. Z. Alshahrani, Hana I. Alsobayel, Mohammed Taher Ahmed Omar, Abdulrahman M. Alsubiheen

“…The randomized controlled trials (RCTs) were included if they were in English, participants aged ≥ 18 years, underwent a unilateral or bilateral TKR and were treated using VRBR. …”
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A prospective randomized placebo-controlled study evaluating the safety and benefits of tranexamic acid injections for primary unilateral total knee replacement by Prashant Bhavani, Suhas Aradhya Bhikshavarthi Math, Mainak Roy, Mulagondla Harshavardhan Reddy, Deepanjan Das, Priyanshu

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Analysis of results to optimize anticoagulant therapy in patients who underwent mechanical heart valve replacement: a pilot singlecenter controlled study by S. A. Uranova-Tkachenko, A. V. Bogachev-Prokophiev, R. M. Sharifulin, Y. M. Smirnov, A. N. Pivkin, A. S. Zalesov, D. A. Astapov

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MODEL OF ADAPTIVE VECTOR CONTROL OF STOCHASTIC HYBRID CACHING ALGORITHM by Alexander I. Zhukov

“…The problem of increasing the cache system efficiency using the adaptive vector control of the stoch a s tic hybrid caching algorithm is investigated. …”
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Reassessing the need for scheduled replacement of short term central venous catheters: A narrative comprehensive review by Regev Cohen

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Enhancing Seismic Repairability of Precast RC Frames Through an Innovative Replaceable Plastic Hinge Technology by Resat Oyguc, Ali Berk Bozan

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