Abstract 072: Risk Factors for Developing Ischemic Strokes While Taking Non‐Vitamin K Antagonist Oral Anticoagulants by Alvin S. Das, Elif Gokcal, Avia Abramovitz Fouks, Mitchell Horn, Robert Regenhardt, Anand Viswanathan, Aneesh Singhal, Lee Schwamm, Steven Greenberg, Edip Gurol

“…Introduction Over the past decade, non‐vitamin K antagonist oral anticoagulants (NOACs) have replaced warfarin as the initial strategy for stroke prevention in non‐valvular atrial fibrillation. …”
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Multiple Approaches to Quantifying the Effective Porosity of Lacustrine Shale Oil Reservoirs in Bohai Bay Basin, East China by Binyu Ma, Qinhong Hu, Shengyu Yang, Na Yin, Hongguo Qiao, Tao Zhang, Mianmo Meng

“…An effective porosity is defined as the ratio of volume of interconnected pore space to total volume of a porous sample. It controls the magnitude of fluid flow and is a key parameter in the assessment of recoverable resources. …”
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Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis by Valerio Secli, Emma Michetti, Francesca Pacello, Federico Iacovelli, Mattia Falconi, Maria Luisa Astolfi, Daniela Visaggio, Paolo Visca, Serena Ammendola, Andrea Battistoni

“…These results unveil an unexpected role for pyochelin in zinc homeostasis and challenge the traditional view of this metallophore exclusively as an iron transporter.IMPORTANCEThe mechanisms underlying the remarkable ability of Pseudomonas aeruginosa to resist the zinc sequestration mechanisms implemented by the vertebrate innate immune system to control bacterial infections are still far from being fully understood. …”
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Comparative effects of different dietary pectin types on growth performance and intestinal health in pearl gentian grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂) by Lulu Zhu, Xiaoxue Meng, Xuehan Wang, Jiongting Fan, Beiping Tan, Junming Deng

“…Four experimental diets were formulated, including an 8 % common low-ester pectin (CLP) diet, 8 % amidated low-ester pectin (ALP) diet, 8 % high-ester pectin (HP) diet, and a control diet in which 8 % pectin was replaced by 8 % dextrin. …”
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Effect of changing the proportion of C16:0 and cis-9 C18:1 in fat supplements on rumen fermentation, glucose and lipid metabolism, antioxidation capacity, and visceral fatty acid p... by Haixin Bai, Lubo Wang, Modinat Tolani Lambo, Yang Li, Yonggen Zhang

“…These adverse effects were alleviated by partially replacing C16:0 with cis-9 C18:1.…”
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Critical Literature Review of Bone Grafts and Orthobiologics for Foot and Ankle Arthrodesis to Facilitate Optimal Clinical Decision Making by Ashley Knight PhD, Eric W. Tan MD, Ioanna W. Bolia-Kavouklis MD

“…Future research will further investigate the role of orthobiologics and their potential to replace autograft to avoid donor site complications during hindfoot and ankle arthrodesis procedures.…”
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Adherence to urate-lowering therapy while following the national guidelines for the management of patients with gout (preliminary evidence) by M. N. Chikina, E. V. Ilyinykh, M. S. Eliseev

“…Due to its inefficacy, allopurinol was replaced by febuxostat in 24 patients. In this group, the target UA level was recorded in 16 (67%) patients. …”
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Comparative evaluation of immunomodulatory cytokines for oncolytic therapy based on a high-efficient platform for oHSV1 reconstruction by Yingzheng Gao, Yufang Zou, Changjing Wu, Juan Tao, Zuqing Nie, Jinyuan Yan, Pengfei Wang, Xinwei Huang

“…Methods We developed a CRISPR/Cas9-mediated platform for high-efficiency oHSV1 engineering, replacing the ICP47 locus with murine IFN-γ, GM-CSF, or IL-15Rα/IL-15 fusion protein (IL15Fu). …”
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Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology. by Andria Mousa, Gina Cuomo-Dannenburg, Hayley A Thompson, R Matthew Chico, Khalid B Beshir, Colin J Sutherland, David Schellenberg, Roly Gosling, Michael Alifrangis, Emma Filtenborg Hocke, Helle Hansson, Ana Chopo-Pizarro, Wilfred F Mbacham, Innocent M Ali, Mike Chaponda, Cally Roper, Lucy C Okell

“…We find that a placebo or control group with no drug protection is valuable but not always feasible. …”
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Compensatory mechanisms in γδ T cell-deficient chickens following Salmonella infection by Felix Tetzlaff, Felix Tetzlaff, Ulrich Methner, Theresa von Heyl, Christian Menge, Benjamin Schusser, Benjamin Schusser, Angela Berndt

“…In later stages of the infection, the γδ T cells and their functions appear to be replaced by other cells.…”
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CLINICAL STUDIES OF MATERIALS FOR TEMPORARY REMOVABLE PROSTHESIS by O.S. Kyrmanov

“…This aspect is particularly important if there is a large middle part of the design and replaced a large amount of hard substance of the tooth (crown thick walls). …”
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Orange-flesh sweet potato powder as a promising partial substitution rice flour to produce high quality and low glycemic index vermicelli by Tran Ngoc Giau, Hong Van Hao, Ngo Van Tai, Vo Quang Minh, Nguyen Minh Thuy

“…This study aims to improve the quality of vermicelli products by replacing a portion of rice flour with orange-fleshed sweet potato powder at four ratios ranging from 10 % (F1) to 25 % (F4) (5 % interval), while the control sample used 100 % rice flour (F0). …”
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Electrophysiological characterisation of intranigral-grafted hiPSC-derived dopaminergic neurons in a mouse model of Parkinson’s disease by Bérengère Ballion, Marie-Laure Bonnet, Sébastien Brot, Afsaneh Gaillard

“…Cell therapy for PD aims to replace lost mDA neurons to restore the DA neurotransmission in the denervated forebrain targets. …”
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Feed-grade hempseed as alternative protein source in organic broilers diet: Growth performance, carcass characteristics and meat quality by Francesco Serrapica, Claudia Lambiase, Felicia Masucci, Ada Braghieri, Jose Manuel Lorenzo, Antonio Di Francia

“…Treatments included a control diet containing 30 % SBE and two experimental diets with FG-HS replacing SBE at 50 % (H15) or 100 % (H30). …”
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Nutritional Enhancement of Crackers Through the Incorporation of By-Products from the Frozen Pumpkin Industry by Miguel A. Gallardo, M. Esther Martínez-Navarro, Irene García Panadero, José E. Pardo, Manuel Álvarez-Ortí

“…Crackers were prepared by replacing 10% and 20% of wheat flour with pumpkin flour, assessing the effects based on drying method. …”
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Nutrient management approach to improve productivity and profitability of pigeonpea (Cajanus cajan) in north east hill zones of India by SARMISTHA SARKAR, BIMAN DE, PARTHA DAS, DEBASREE SAHA, DURGA PRASAD AWASTHI, NILADRI PAUL, DEBASHISH SEN

“…Results indicated that applying vermicompost @5 t/ha and phosphorus-solubilizing bacteria @30 kg/ha markedly increased number of nodules (17.38) and leaf area index (5.54) at 90 and 120 days after sowing, respectively, with highest seed yield (1.90 t/ha) and stover yield (7.93 t/ha), when 50% of recommended doses had been replaced. Nutrient uptake, soil availability and microbial populations also showed the same trends. …”
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Antimicrobial and antifungal activity of some (5-(adamantane-1-yl)-4R-1,2,4-triazole-3-ylthiols substitutes by V. M. Odyntsova

“…The substance of the antibacterial drug Trimethoprim has been applied as a control in determining antimicrobial activity of the compounds against the investigated strains of microorganisms. …”
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Green Approach in Obtaining Grape Extracts Displaying Cytotoxic Activity by Nevena Dabetic, Vanja Todorovic, Jelena Antic Stankovic, Dragana Bozic, Ivana Djuricic, Sladjana Sobajic

“…For this reason, there is an aspiration to replace widely used organic solvents with greener ones. …”
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Estimating the prediction ability of reverse degree-based entropy indices for the physicochemical properties of lymes disease drugs by Guoping Zhang, Guoping Zhang, Yali Li, Yali Li, Abdul Rauf, Muhammad Aamir Afzal, Parvez Ali, Adnan Aslam

“…While this framework offers a cost-effective preliminary tool for predicting physicochemical properties, it complements rather than replaces rigorous experimental validation required for regulatory reporting. …”
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Performance of Banana Peelings Extract as A Natural Coagulant in the Treatment of Surface Water Case Study: River Rwizi, Mbarara. by Asingya, Derrick

“…However, many researchers have come up with different plant-based coagulants to replace Aluminum sulphate thus, the main objective of this research was to the investigate performance of banana peelings extract as a natural coagulant in the treatment of surface water by comparing the coagulation action of the raw and ripe banana peelings extracts against Aluminium sulphate, a chemical coagulant as the control experiment. …”
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