Rapid iPSC-derived neuromuscular junction model uncovers motor neuron dominance in amyotrophic lateral sclerosis cytopathy by Hsiao-Chien Ting, Yun-Ting Guo, Hong-Lin Su, Yu-Shuan Chen, Shinn-Zong Lin, Horng-Jyh Harn, Chia-Yu Chang

“…Quantitative analysis of 3D confocal microscopy images revealed a critical role of MNs in initiating ALS-related NMJ cytopathies, characterized by alterations in the volume, number, intensity, and distribution of acetylcholine receptors, ultimately leading to impaired muscle contractions. Our rapid and precise in vitro NMJ model offers significant potential for advancing research on NMJ physiology and pathology, as well as for developing treatments for NMJ-related diseases.…”
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Instance-level semantic segmentation of nuclei based on multimodal structure encoding by Bo Guan, Guangdi Chu, Ziying Wang, Jianmin Li, Bo Yi

“…The framework incorporates: (1) A multi-scale feature fusion and knowledge distillation module utilizing the Contrastive Language-Image Pre-training (CLIP) model’s image encoder; (2) A method to transform morphological features of cells into textual descriptions for semantic representation; and (3) A graph neural network approach to learn spatial relationships and contextual information between cell nuclei. …”
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CNP-pGC-cGMP-PDE3-cAMP Signal Pathway Upregulated in Gastric Smooth Muscle of Diabetic Rats by Ying-Lan Cai, Mo-Han Zhang, Xu Huang, Jing-Zhi Jiang, Li-Hua Piao, Zheng Jin, Wen-Xie Xu

“…The results demonstrated that the inhibitory effect of CNP on the spontaneous contraction of gastric antral circular smooth muscle was potentiated in STZ-induced diabetic rat. …”
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Global, regional, and national burden of esophageal cancer using the 2019 global burden of disease study by Liangchao Sun, Kaikai Zhao, Xiaoli Liu, Xue Meng

“…Over the past three decades, esophageal cancer has exhibited a substantial global burden, marked by a significant increase in absolute numbers, contrasting with a decline in age-standardized metrics. …”
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Gene metabolite relationships revealed metabolic adaptations of rice salt tolerance by Mojdeh Akbarzadeh Lelekami, Mohammad Hadi Pahlevani, Khalil Zaynali Nezhad, Keyvan Mahdavi Mashaki

“…This study examined the effects of high salinity on the roots and shoots of rice genotypes with contrasting tolerances: CSR28 (tolerant) and IR28 (sensitive) at the seedling stage. …”
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Versatile application of fast green FCF as a visible cholangiogram in adult mice to medium-sized mammals by Tomoyuki Niimi, Nanae Miyazaki, Hironobu Oiki, Mami Uemura, Shihan Zeng, Watcharapon Promsut, Noriaki Ota, Shunji Nonaka, Hajime Takei, Hiroshi Nittono, Seiko Narushima, Ayaka Yanagida, Ryuji Hiramatsu, Masami Kanai-Azuma, Shohei Takami, Jun Fujishiro, Yoshiakira Kanai

“…In Mab21l1 −/− mice with contracted gallbladders, FG influx was limited to the gallbladder neck. …”
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Coping strategies of fathers and siblings of children with cancer: a literature review by Teresa Rea, Vincenza Sansone, Andrea Zibaldo, Anna Bellingrath, Assunta Guillari

“…The three categories have in common the expression of contrasting feelings by each member of the family that generates changes in roles and responsibilities.Conclusions Further studies are needed to better understand how nurses can lead a family centred care approach to improve the general familiar management and coping strategies.…”
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EEG Correlates of Central Origin of Cancer-Related Fatigue by Didier Allexandre, Dilara Seyidova-Khoshknabi, Mellar P. Davis, Vinoth K. Ranganathan, Vlodek Siemionow, Declan Walsh, Guang H. Yue

“…EEG was examined during a sustained submaximal contraction (SC) task to further understand our prior research findings of greater central contribution to early fatigue during SC in CRF. …”
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Th17: A New Participant in Gut Dysfunction in Mice Infected with Trichinella spiralis by Yu Fu, Wenfeng Wang, Jingjing Tong, Qi Pan, Yanqing Long, Wei Qian, Xiaohua Hou

“…When jejunual smooth muscle strips were cultured with IL-17, contractions elicited by Ach were enhanced in a concentration-dependent manner. …”
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Ion‐Permeable Electrospun Scaffolds Enable Controlled In‐Vitro Electrostimulation Assay of Myoblasts by Serafina Pacilio, Francesco Decataldo, Roberta Costa, Tobias Cramer, Beatrice Fraboni, Giovanna Cenacchi, Maria Letizia Focarete

“…The induction of electric fields orthogonal to the scaffold surface allows for accurately mimicking the excitation‐contraction coupling mechanism observed in native skeletal muscle tissue. …”
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The Genetic Diversity, Population Structure, and Historical Dynamics of Wild <i>Pyrus</i> Species on the Yunnan–Kweichow Plateau by Xiang Yang, Xingguang Dong, Kunming Li, Ying Zhang, Chenxi Xu, Hongliang Huo, Luming Tian, Jiayu Xu, Chao Liu, Dan Qi, Yufen Cao

“…Demographic analyses indicated that wild <i>Pyrus</i> populations on the Yunnan–Kweichow Plateau are currently in a state of population contraction, with evidence of migration events between these populations.…”
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Replication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population by Nam Hee Kim, Young Jin Kim, Ji Hee Oh, Yoon Shin Cho

“…Considering that the GJA1-encoded protein is a major component of cardiac gap junctions, a functional study might be necessary to validate its genuine molecular biological role in the synchronized contraction of the heart.…”
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Adult Wilms Tumor With Inferior Vena Cava Thrombus on an Incomplete Duplex Collecting System Ureter Fissus Proximalis Managed at a Tertiary Hospital in Tanzania: A Case Report and... by Amini Mitamo Alexandre, Joseph Martin Lori, Gabriel F. Mtaturu, Victor Patrick Sensa, Sylvia Bedas Nsato, Mariam Athumani Mbezi, Obadia V. Nyongole, Charles A. Mkony

“…A 28‐year‐old female patient presented to our department with a 4‐month history of right flank pain and flank mass and was diagnosed by abdominal contrasted CT to have a right renal tumor with tumor thrombi in the renal vein and the inferior vena cava. …”
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Potential Use of Essential Oil Isolated from Cleistocalyx operculatus Leaves as a Topical Dermatological Agent for Treatment of Burn Wound by Gia-Buu Tran, Nghia-Thu Tram Le, Sao-Mai Dam

“…Among three groups of mice, wound contraction rate of essential oil treated group (100%) was significantly higher than tamanu oil treated (79%) and control mice (71%) after 20 days (0.22±0.03 versus 0.31±0.02 cm2, resp., p<0.05). …”
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Ethics and Biosafety in Dental Care for Patients with Human Immunodeficiency Virus by Ana Ibis Betancourt García, Carlos Lázaro Nodal García, Jorge Manuel García Rodríguez, Diosky Ferrer Vilches, Elizabeth Álvarez Heredia

“…<strong>Background:</strong> the only way of contracting human immunodeficiency virus during dental treatment is through contact with the blood of an HIV-positive patient with non-intact skin or mucosa of the professional. …”
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Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations by Hewison, A.J. Mark, Bonnot, Nadège C., Gaillard, Jean-Michel, Kjellander, Petter, Lemaitre, Jean-François, Morellet, Nicolas, Pellerin, Maryline

“…We investigated sex differences in over winter body mass change across five intensively monitored populations of roe deer (Capreolus capreolus) with markedly contrasting environmental conditions. At winter onset, males weighed, on average, 8.4% (from 4.7% in the most northerly population to 11.6% in the most southerly one) more than females. …”
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Combined Input Deep Learning Pipeline for Embryo Selection for In Vitro Fertilization Using Light Microscopic Images and Additional Features by Krittapat Onthuam, Norrawee Charnpinyo, Kornrapee Suthicharoenpanich, Supphaset Engphaiboon, Punnarai Siricharoen, Ronnapee Chaichaowarat, Chanakarn Suebthawinkul

“…In addition, a custom weight was trained using a self-supervised learning framework known as the Simple Framework for Contrastive Learning of Visual Representations (SimCLR) in cooperation with generated images using generative adversarial networks (GANs). …”
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Public health implications of Bovine Cysticercosis from Cattle slaughtered at Dilla Municipal abattoir, Southern Ethiopia by Fikadu Tesfaye, Jemere Bekele, Mesele Abera, Nebyou Moje Hawas

“…Of the total 69 interviewed respondents, 57.79% (40/69) had contracted T. saginata infection. The majority of the respondent had an experience of raw meat consumption (65.2%; 45/69) as a result of traditional and cultural practice. …”
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Soil Acidobacterial 16S rRNA Gene Sequences Reveal Subgroup Level Differences between Savanna-Like Cerrado and Atlantic Forest Brazilian Biomes by Elisa C. P. Catão, Fabyano A. C. Lopes, Janaína F. Araújo, Alinne P. de Castro, Cristine C. Barreto, Mercedes M. C. Bustamante, Betania F. Quirino, Ricardo H. Krüger

“…16S rRNA sequences from the phylum Acidobacteria have been commonly reported from soil microbial communities, including those from the Brazilian Savanna (Cerrado) and the Atlantic Forest biomes, two biomes that present contrasting characteristics of soil and vegetation. …”
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Investigation of Complex Characteristics of Waterjet Propulsion Device with Intake Grid by Can Luo, Shuaihao Lei, Chuan Wang, Li Cheng, Chenzhi Xia, Di Zhang, Qiang Guo

“…The causes of hydraulic loss in the contraction segment and straight pipe segment are the intake grid and the inflow velocity, respectively; meanwhile, the loss in the belt pipe segment owes to the vortex, flow separation, and impact on the back. …”
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