Changes of Radial Diffusivity and Fractional Anisotopy in the Optic Nerve and Optic Radiation of Glaucoma Patients by Tobias Engelhorn, Georg Michelson, Simone Waerntges, Marlen Otto, Ahmed El-Rafei, Tobias Struffert, Arnd Doerfler

“…Regions of interest were positioned on RD and FA maps, and mean values were calculated for ON and OR and correlated with optic nerve atrophy and reduced spatial-temporal contrast sensitivity (STCS) of the retina. We found, that RD in glaucoma patients was significantly higher in the ON (0.74 ± 0.21 versus 0.58 ± 0.17⋅10−3 mm2 s−1; P<0.05) and OR (0.79 ± 0.23 versus 0.62 ± 0.14⋅10−3 mm2 s−1; P<0.05) compared to controls. …”
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Epstein-Barr Virus Encephalitis in an Immunocompetent Child: A Case Report and Management of Epstein-Barr Virus Encephalitis by Gulsen Akkoc, Eda Kepenekli Kadayifci, Ayse Karaaslan, Serkan Atici, Nurhayat Yakut, Sevliya Ocal Demir, Ahmet Soysal, Mustafa Bakir

“…Cranial magnetic resonance imaging showed contrast enhancement in the bilateral insular cortex and the right hypothalamus. …”
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Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis by Blake A. Caldwell, Susanti Ie, Amy Lucas, Liwu Li

“…After one week of recovery, we profiled bone marrow and splenic reservoir monocytes in Ticam2 -/- mice and found that, in contrast to the persistent exhaustion observed in wild-type monocytes, Ticam2 -/- monocytes largely resembled healthy controls. …”
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Aromatic Amino Acid Mutagenesis at the Substrate Binding Pocket of Yarrowia lipolytica Lipase Lip2 Affects Its Activity and Thermostability by Guilong Wang, Zimin Liu, Li Xu, Yunjun Yan

“…Though its crystal structure has been resolved, its structure-function relationship has rarely been reported. By contrast, there are two amino acid residues (V94 and I100) with significant difference in the substrate binding pocket of YLLip2; they were subjected to site-directed mutagenesis (SDM) to introduce aromatic amino acid mutations. …”
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Climate change impacts on flood risks in the Abou Ali River Basin, Lebanon: A hydrological modeling approach by Fouadi AlZaatiti, Jalal Halwani, Mohamed R. Soliman

“…The findings show an overall decrease in precipitation of -10.8 % (ACCESS-CM2) and -13.2 % (MIROC6) under SSP5–85, respectively, aligning with broader regional trends. In contrast, BCCCSM2-MR predicts an 8 % increase in precipitation, under the same scenario. …”
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Referral to an Electronic Screening and Brief Alcohol Intervention in Primary Health Care in Sweden: Impact of Staff Referral to the Computer by Preben Bendtsen, Diana Stark Ekman, AnneLie Johansson, Siw Carlfjord, Agneta Andersson, Matti Leijon, Kjell Johansson, Per Nilsen

“…Staff-referred responders reported reduced weekly alcohol consumption with an average decrease of 8.4 grams. In contrast, self-referred responders reported an average increase in weekly alcohol consumption of 2.4 grams. …”
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Spastic Paraparesis in Young Men With Spinal Meningioma and Spinal Arteriovenous Malformation: A Case Report by Leonard Christianto Singjie, Ivan Jeremia, Esdras Ardi Pramudita

“…Laminectomy and extirpation of the spinal meningioma were done as the gold standard of therapy, and the symptom was relieved. In contrast, spinal AVM was not performed­ and is still under observation.…”
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DREDGING IMPACT ON THE LAKE MANZHEROK (REPUBLIC OF ALTAY) HYDRO/ BIOLOGICAL AND SANITARY/MICRO/BIOLOGICAL CHARACTERISTICS by Dmitry M. Bezmaternykh, Vladimir V. Kirillov, Nadezhda I. Yermolaeva, Laura M. Kipryanova, Lyubov V. Yanygina, Elena Y. Mitrofanova, Olga N. Vdovina, Anton V. Kotovschikov, Evgeniya Y. Zarubina

“…In comparison with 2015 the filtering zooplankton organisms’ abundance and biomass were 10–15 times lower. In contrast with 14–15 species in previous years we identified 5 species of macrophytes. …”

Procalcitonin and C-reactive protein - early predictors of low colorectal anastomotic leakage by Yu. A. Shelygin, M. A. Tarasov, M. A. Sukhina, I. V. Zarodnyuk, Ye. G. Rybakov

“…AL was diagnosed in 20% (20 of 100) of patients: in 11% (11 of 100) - with clinical manifestations, in 9% (9 of 100) - without clinical symptoms (contrast leakage according to X-ray study). In the group of patients with anastomotic leak, the median of C-reactive protein level differed from that in patients with uncompromised integrity of anastomosis at 3rd day after surgery (156 mg/L vs 81 mg/L, respectively - t-test, p=0.0004) and postoperative day 6 (136 mg/L vs. 52 mg/L, respectively - t-test, p…”
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Time series models for prediction of leptospirosis in different climate zones in Sri Lanka. by Janith Warnasekara, Suneth Agampodi, Rupika Abeynayake

“…There was no association with RH in contrast to previous studies. Based on altitude and rainfall data, meteorological variables could effectively predict the incidence of leptospirosis with different models for different climatic zones. …”
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A case of sclerosing angiomatoid nodular transformation with central calcification by Eri Nakamura, MD, Yasutaka Ichikawa, MD, PhD, Kensuke Domae, MD, Yuzuna Aoki, MD, Yoichi Kozaki, MD, Miki Usui, MD, Akito Taniguchi, MD, Motonori Nagata, MD, PhD, Hajime Sakuma, MD, PhD

“…Image findings of SANT have been reported as low signal intensity on T2-weighted magnetic resonance (MR) images and a characteristic enhancement pattern on dynamic contrast-enhanced computed tomography (CT) and MR images. …”
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The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke by Katherine Hernandez, Nathan Jones, Sterling B. Ortega

“…Seventy-two hours later, behavior function and infarct area were assessed.ResultsIn contrast to previous rat studies that demonstrated improvements in clinical outcomes, a single administration of PNU following stroke induction led to a reduction in acute neuropathology but did not produce a significant improvement in motor outcomes. …”
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TYPOCHEMISTRY OF MAGNETITE FROM MASSIVE SULFIDE AND IRON DEPOSITS OF THE URALS ACCORDING TO LA-ISP-MS DATA by V.V. Maslennikov, N.R. Ayupova, A.S. Tseluyko, N.P. Safina, D.A. Artemyev, U.A. Yatimov, S.I. Bryukhov, P.V. Khvorov, M.A. Rassomakhin

“…It is established using laser ablation inductively coupled plasma mass spectrometry (LA-ICPMS) that, in contrast to magnetite of iron deposits, magnetite of ore-controlling volcanosedimentary horizons of the Urals massive sulfide deposits is characterized by a higher content and stable associations of Bi, Te, Co, As, Cd, Zn, Cu and Mo due to relict inclusions of sulfide clasts and products of their halmyrolysis. …”
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Deformation and strengthening behavior of Al-Cu-based alloys at ambient and elevated temperatures by Mehran Shahhosseininia, Mohammadreza Zamani

“…SEM images illustrated that as-cast and heat-treated Al-Cu-Mg and Al-Cu-Mg-Ag alloys underwent a brittle deformation with intergranular-transgranular fracture mechanisms at ambient temperature. In contrast, at elevated testing temperatures, some dimples were observed to form. …”
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ARTIFICIAL INTELLIGENCE IN BUSINESS OPERATIONS: EXPLORING PRODUCTIVITY AND ACCEPTANCE by Ioana CIOFU, Giulia KONDORT, Stefana POP, Roxana CIOC

“…This is likely to reflect their familiarity with technology. In contrast, older respondents exhibited lower levels of trust and acceptance, particularly in contexts requiring precision, such as financial transactions. …”
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Climate sensitivity and attribution analysis of water resources in China by Youzhu Zhao, Qiuxiang Jiang, Zilong Wang

“…Previous studies have focused on TWS sensitivity to a single climate variable, such as precipitation or temperature. In contrast, this study examines TWS sensitivity to both, revealing regional variations. …”
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Pseudogenization of the Slc23a4 gene is necessary for the survival of Xdh-deficient mice by Kazuki Terada, Tamaki Watanabe, Nobuhiro Yasuno, Toshio Ohtsubo, Shigeru Shibata, Kimiyoshi Ichida, Makoto Hosoyamada

“…Abstract In most patients with type 1 xanthinuria caused by mutations in the xanthine dehydrogenase gene (XDH), no clinical complications, except for urinary stones, are observed. In contrast, all Xdh(− / −) mice die due to renal failure before reaching adulthood at 8 weeks of age. …”
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Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy by Moein Ala

“…Sestrin2 knockdown aggravated diabetic nephropathy in animal models. In contrast, upregulation of Sestrin2 enhanced autophagy, mitophagy, and mitochondrial biogenesis and suppressed oxidative stress, ER stress, and apoptosis in diabetic nephropathy. …”
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Newer Oral Anticoagulants in the Treatment of Acute Portal Vein Thrombosis in Patients with and without Cirrhosis by P. Priyanka, J. T. Kupec, M. Krafft, N. A. Shah, G. J. Reynolds

“…NOAC use is the standard of care for stroke prophylaxis in nonvalvular atrial fibrillation and treatment of acute VTE involving extremities and pulmonary embolism. In contrast, most guidelines in the literature support the treatment of acute portal vein thrombosis (PVT) with low molecular weight heparin (LMWH) and vitamin K antagonists (VKA). …”
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Identification of mitochondrial carrier homolog 2 as an important therapeutic target of castration-resistant prostate cancer by Yankui Liu, Anjie Chen, Yufan Wu, Jiang Ni, Rong Wang, Yong Mao, Ning Sun, Yuanyuan Mi

“…The silencing or KO of MTCH2 significantly inhibited cell viability, proliferation, and migration, together with a marked increase in apoptosis in the primary CRPC cells. In contrast, ectopic expression of MTCH2 provided CRPC cells with pro-tumorigenic properties, enhancing ATP production and promoting cell proliferation and migration. …”
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