Closing the loop: establishing an autonomous test-learn cycle to optimize induction of bacterial systems using a robotic platform by Jan Benedict Spannenkrebs, Aron Eiermann, Thomas Zoll, Silke Hackenschmidt, Johannes Kabisch, Johannes Kabisch, Johannes Kabisch

“…As a result, even in times of rapidly advancing artificial intelligence, the common design-build-test-learn (DBTL) cycle is still not circular without human intervention. …”
Get full text

Halo-RPD: searching for RNA-binding protein targets in plants by A. O. Shamustakimova

“…Currently, various methods are available to investigate these interactions with, RNA immunoprecipitation (RIP) being the most common. The search for RNA targets has largely been conducted using antibodies to an endogenous protein or to GFP-tag directly. …”
Get full text

The Red Supergiant Progenitor Luminosity Problem by Emma R. Beasor, Nathan Smith, Jacob E. Jencson

“…How close is this to the bolometric luminosity for that same star inferred from the full optical-to-IR spectral energy distribution (SED)? We find common assumptions adopted in progenitor studies systematically underestimate the bolometric luminosity by a factor of 2, typically leading to inferred progenitor masses that are systematically too low. …”
Get full text

Mechanisms of (Fisch.) Bge. var. mongholicus (Bge.) Hsiao (huang qi) and (Oliv.) Diels (dang gui) in Ameliorating Hypoxia and Angiogenesis to Delay Pulmonary Nodule Malignant Tra... by Ying Guo PhD, Peng Yang MS, Zihong Wu PhD, Sanyin Zhang PhD, Fengming You PhD

“…In traditional Chinese medicine (TCM), PN is referred to as “Feiji,” which is mainly attributed to Qi and blood deficiency, correspondingly, the most commonly prescribed medicines are Astragalus membranaceus (Fisch.) …”
Get full text

Disruption Risk Analysis of Substitutable Dual Product Supply Chain: A System Dynamics Framework by Jing Ke, Weiqiang Jia, Ye Zhou, Xin Wang

“…In addition, the disruption of traditional products will cause consumers to flow to the green product market, resulting in a sudden increase in order for green products and components in a short period of time, causing a delayed impact on the inventory of suppliers and manufacturers of green products. (2) The disruption of upstream suppliers in traditional products causes the highest profit losses for all traditional product suppliers, while the disruption of downstream suppliers in green products causes the highest profit losses for the manufacturer and all green product suppliers. (3) From the perspective of the service level, compared to other components, the disruption of critical components in traditional products poses the highest risk of out of stock in the supply chain, while the risk of out-of-stock in the intermediate component of green product is the smallest. (4) Common sense may suggest that the more the suppliers disrupt, the higher the damage of the supply chain. …”
Get full text

Comprehensive Analysis of <i>blaCTX-M1</i> Gene Expression Alongside <i>iutA</i>, <i>csgA</i>, and <i>kpsMII</i> Virulence Genes in Septicemic <i>Escherichia coli</i> Using Real-Ti... by Mohsen Karbalaei, Mojgan Esmailpour, Valentyn Oksenych, Majid Eslami

“…<b>Results:</b> Antibiotic resistance was common in isolates carrying <i>blaCTX-M1</i>, including tetracycline (93%) and erythromycin (99%). …”
Get full text

Clinicopathological features of Lynch syndrome pedigrees with MSH2 c.351G>A gene variant by Shuai Zhang, Guanyu Fu, Gongping Sun, Yuanxin Tang, Jin Meng, Zhigang Wang, Rongjun Su, Wei Liu, Xiaoxia Li

“…The clinicopathological characteristics of LS in this family include common simultaneous or heterogeneous multiple primary cancers, a broad tumor spectrum, and a younger age with the continuation of genetic algebra.…”
Get full text

Sofosbuvir Based Regimens in the Treatment of Chronic Hepatitis C with Compensated Liver Cirrhosis in Community Care Setting by Vijay Gayam, Amrendra Kumar Mandal, Mazin Khalid, Osama Mukhtar, Arshpal Gill, Pavani Garlapati, Mowyad Khalid, Mohammed Mansour

“…Fatigue (35%) was the most common adverse effect and no patients discontinued treatment due to adverse effects. …”
Get full text

A genome-wide association study identified SNP markers and candidate genes associated with morphometric fruit quality traits in mangoes by Shamseldeen Eltaher, Jin Li, Barbie Freeman, Sukhwinder Singh, Gul Shad Ali

“…Of these markers, 7 were commonly associated with different traits, while 96 markers were uniquely associated with specific traits. …”
Get full text

Association of polymorphism <i>TP53</i> Arg72Pro with radon-induced lung cancer in the Kazakh population by O. Bulgakova, A. Kussainova, A. Kakabayev, А. Kausbekova, R. Bersimbaev

“…The tumor suppressor gene TP53 is a key mediator of the DNA damage response cascade following cell exposure to ionizing radiation. The common polymorphism TP53 Arg72Pro (rs1042522) is a risk factor for lung cancer in the Asian population, but until now no genetic association studies have been done in the Kazakh population. …”
Get full text

Genetic causality between insomnia and specific orthopedic conditions: Insights from a two-sample Mendelian randomization study by Mingyi Yang, Jiale Xie, Yani Su, Ke Xu, Pengfei Wen, Xianjie Wan, Hui Yu, Zhi Yang, Lin Liu, Peng Xu

“…Objective: To investigate the genetic causality for the insomnia and common orthopedic diseases, such as rheumatoid arthritis (RA), ankylosing spondylitis (AS), osteoporosis (OP), and gout (GT). …”
Get full text

Development of the modified Safety Attitude Questionnaire for the medical imaging department by Ravi Chanthriga Eturajulu, Maw Pin Tan, Mohd Idzwan Zakaria, Karuthan Chinna, Kwan Hoong Ng

“…Introduction: Medical errors commonly occur in medical imaging departments. These errors are frequently influenced by patient safety culture. …”
Get full text

The presence of risk factors in the home environment that influences the fall of people of the third age by Ratko Zlatičanin, Amila Jaganjac, Arzija Pašalić, Amra Mačak Hadžiomerović

“…According to the World Health Organization, falls are the second leading cause of unintentional injury death in the world and represent a major global public health problem. Falls are most commonly caused by intrinsic and extrinsic risk factors. …”
Get full text

Picking interstitial lung disease out of the myositis haystack by Jennifer Hannah, Harsha Gunawardena

“…Interstitial lung disease (ILD) is a common manifestation of the connective tissue disease (CTD) associated idiopathic inflammatory myopathies (IIM). …”
Get full text

Diversity of frontier processes in Amazonian subnational jurisdictions: Frontier metrics reveal major patterns of human–nature interactions by Guido Briceño, Julie Betbeder, Agnès Bégué, Guillaume Cornu, David Katz-Asprilla, Marie-Gabrielle Piketty, Solen Le Clech, Vinicius Silgueiro, Hélène Dessard, Lilian Blanc

“…This approach provides valuable insights for stakeholder to target interventions and policies adapted to each archetype, for example, payment for ecosystem services, command and control policies, land tenure regulations, land restoration strategies or land use intensification.…”
Get full text

Heterogeneity of Clostridioides difficile asymptomatic colonization prevalence: a systematic review and meta-analysis by Daniel De-la-Rosa-Martínez, Rodrigo Villaseñor-Echavarri, Diana Vilar-Compte, Virna Mosqueda-Larrauri, Paola Zinser-Peniche, Seth Blumberg

“…Conclusion Our study revealed that tCDAC is a common phenomenon. We found high prevalence estimates that showed significant variability across populations. …”
Get full text

Presentation of Religious Tourism Pattern Based on Foundation Data Theory in International Borders by Ali Rostami, Mohammad Aidi, Alireaza slambolchi, Mohammadreza Rabiee Mandejin

“…Having determining the sample size qualitatively via snowball method, 14 experts of religious tourism including academics and trustees of religious tourism were recognized and they were interviewed directly and the research findings showed that religious tourism pattern in Mehran International Border has six main components including casual conditions (religious and tribal communities, provincial infrastructures, common border of Iraq and vicinity to The Holy of Holies, advertisements) categories (tourism and its subcategories, religious places in Iran and Iraq, security) grounds (commercial free zone in Mehran welfare and health services, economic part of religious tourism), interferer factors (political factors, conveying affairs to non-governmental sector, weather changes), strategies (cooperating with educational centers and universities, increasing governmental investing, using capacities of religious days) consequences & results (income and creating jobs, people’s persistence in border and non-immigration, cultural development of province, destruction of environmental, road and jungles of province) which could be introduced as a proper pattern for religious tourism in Mehran International Border according to the opinion of experts. …”
Get full text

Comparison of Renal Tubular Damage with Kidney Injury Molecule-1 in Open and Laparoscopic Colorectal Cancer Surgery by Abdullah Gürhan Duyan, Celalettin Vatansev, Rahim Kocabaş, Melek Yalçın Koç, Muhammed Ali Akbulut

“…<i>Background and Objectives</i>: Colorectal cancer is the third most common type of cancer in men and women. With advancements in technology, minimally invasive treatment options have become increasingly prominent in colorectal cancer surgery. …”
Get full text

Effects of Mulch Type, Plant Cultivar, and Insecticide Use on Sweet Potato Whitefly Population in Chili Pepper by Andi Nasruddin, Nurariaty Agus, Alam Saubil, Jumardi Jumardi, Burhanuddin Rasyid, Andry Siriniang, Andi Dirham Nasruddin, Firdaus Firdaus, Ahwiyah Ekawaty Said

“…This approach could substantially reduce the number of insecticide applications from twice per week (commonly practiced by chili farmers in the area) to one application only in two weeks.…”
Get full text

Epidemiological analysis of reported acute glyphosate poisoning in Malaysia: identifying risk factors and high-risk groups (2006–2023) by Yin-Hui Leong, Noor Afiza Abdul Rani, Mohd Fadhli Razali, Nurul Iffah Amir Shah Ruddin, Fahim Mohamed, Nurul Izzah Ahmad

“…From 2013 to 2023, 73.7% of cases were minor, 11.5% moderate, 0.8% severe and 0.1% fatal.Conclusions In Malaysia, the reported intentional glyphosate poisoning most commonly affects young adults, resulting in generally minor to moderate symptoms. …”
Get full text