TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles by Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Konstantina Psatha, Dimitris Kletsas, Michalis Aivaliotis, Carl-Henrik Heldin, Aristidis Moustakas

“…EVs transport transforming growth factor-β (TGF-β), which is commonly activated under late stages of cancer progression. …”
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Lenvatinib Therapy in Patients with Unresectable Hepatocellular Carcinoma in Real Clinical Practice by V. V. Petkau, A. V. Sultanbaev, K. V. Menshikov, A. S. Antipin, M. V. Volkonsky, V. M. Filippova, Yu. V. Vasilyeva, A. A. Tarkhanov, M. R. Mukhitova, M. Zh. Murzalina, A. R. Safarova

“…AEs were registered in 81.0% (n = 47) of patients. Among the most common AEs were arterial hypertension (32.8 %), weakness (24.1 %), weight loss (12.1 %) and appetite loss (10.3 %). …”
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Evaluation of the Antimicrobial Activity of Phytochemicals from Tea and Agarwood Leaf Extracts against Isolated Bacteria from Poultry and Curd by Shah Rucksana Akhter Urme, Syeda Fahmida Ahmed, Mohammed Mostafa Al Quadir, Mst Rubaiat Nazneen Akhand, Mohammad Mehedi Hasan Khan

“…Antibiotic-resistant bacteria are becoming increasingly common, leading to a global health crisis. The effects of abusing antibiotics not only increase pathogenic resistance but also cause various diseases and syndromes. …”
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Application of Patient-Generated Health Data Among Older Adults With Cancer: Scoping Review by Yesol Kim, Geonah Kim, Hyeonmi Cho, Yeonju Kim, Mona Choi

“…Almost half of the studies were conducted in North America (38/88, 43%), followed by Europe (30/88, 34%). The most common setting in which the studies were conducted was the participant’s home (69/88, 78%). …”
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Interstep Variations of Stairways and Associations of High-Contrast Striping and Fall-Related Events: Observational Study by Sara A Harper, Chayston Brown, Shandon L Poulsen, Tyson S Barrett, Christopher J Dakin

“…Unfortunately, interstep variations in riser height and depth are common, particularly in older stairways, but its impact may be lessened by highlighting steps’ edges using a high-contrast stripe on the top front edge of each step. …”
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Treatment of chronic hepatitis C by cepeginterferon alpha-2b in combination to ribavirin by M. V. Mayevskaya, O. O. Znoyko, Ye. A. Klimova, S. L. Maximov, S. N. Kizhlo, N. A. Petrochenkova, F. I. Nagimova, Yu. N. Linkova

“…Therefore the response at the end of treatment (direct virologic response, DVR) and sustained virologic response (SVR) were estimated for patients of the 1-st and 2-nd groups in common (n=100). Among patients with HCV 2/3 genotypes, receiving Algeron, DVR was observed in 93,6%, in control group – in 81,8%, in patients with the 1-st virus genotype — in 83 and 71,4 % of cases respectively (р>0,05 at comparison of all scores between groups). …”
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Olutasidenib in combination with azacitidine induces durable complete remissions in patients with relapsed or refractory mIDH1 acute myeloid leukemia: a multicohort open-label phas... by Jorge E. Cortes, Gail J. Roboz, Maria R. Baer, Brian A. Jonas, Gary J. Schiller, Karen Yee, P. Brent Ferrell, Jay Yang, Eunice S. Wang, William G. Blum, Alice Mims, Hua Tian, Aaron Sheppard, Stéphane de Botton, Pau Montesinos, Antonio Curti, Justin M. Watts, the Olutasidenib Combination Therapy Study Group

“…In patients who achieved CR/CRh and were transfusion-dependent at baseline, transfusion independence (RBC and platelets) was achieved in 64% (7/11) and 57% (4/7) of patients, respectively. The most common Grade 3 or 4 adverse events (> 20% patients) were decreased platelet count (37%), red blood cell count (25%), and neutrophil count (24%). …”
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Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM by Fuxiang Luan, Yuying Cui, Ruizhe Huang, Zhuojie Yang, Shishi Qiao

“…Genetic analysis revealed that Deep deletions were the most common type of NTN1 alteration. Additionally, a positive correlation was observed between NTN1 CNAs and its expression levels. …”
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Designing and modeling an intelligent system for managing the distribution and scheduling of farmed fish feed using the Arduino Uno microcontroller by Shayesteh Tabatabaei

“…In this system, at the specified time, the Arduino board sends a command to activate the servo motor. Upon activation, the gears of the servo motor rotate in four different positions, determined by the set time for the feeding session, causing the feeder connected to the motor to rotate. …”
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The Effects of Artificial vs. Natural Rearing on Growth Performance, Thyroid Hormone Levels, Locomotor Activity, Carcass Traits and Meat Quality Characteristics in Chios Lambs by Panagiotis Simitzis, Georgia Alexopoulou, Eftychis Karampekos, Konstantina Linardopoulou, Anargyros Rigakis, Niki Stamelou, Michael Goliomytis, Iosif Bizelis, Ioannis Bossis

“…Artificial rearing (AR) of lambs is nowadays a common practice in Mediterranean dairy sheep production systems to enhance the milk available for cheese or yoghurt manufacturing. …”
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Development of a Comprehensive Fall Risk Assessment Tool for Older People in Elderly Care Institutions and Its Test by LUO Yuan, ZHANG Hua, WANG Sanxiang, ZHANG Mengxi, DENG Yuqian, RAN Haiye, LIU Jiaxin, ZHANG Yi, CHEN Xi, WU Yibo, ZHAO Liping

“…Conclusion This study has developed a comprehensive fall risk assessment tool for elderly people in elderly care institutions, which contains three sub-instruments that complement each other to improve the whole pathway from assessment to prevention, with good reliability, validity and predictive ability, and can provide a reference for fall prevention and management in the future.…”
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Maximizing the potential of water buffalo milkability: best practices and lessons learned by Carlo Boselli, Antonio Borghese

“…In buffalo milking management, the milking machine is a critical point, and the characteristics of the milking vacuum and the pulsation rate are closely related to milk flow observations; in Italy, the most commonly used vacuum levels are 44–46 kPa (range 40–53 kPa). …”
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Advertising in Lithuanian Periodicals in 1918-1940: Characteristics of its Quantitative and Qualitative Developement by Giedrė Polkaitė

“…Advertising of warehouses, shops, and goods contained therein rather than that of separate trademarks or brand products was much more common.   2) 1921-1926 - it did not take long for advertising to come to life again following economic and political disturbances. …”
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Digital Surveillance of Mental Health Care Services in Saudi Arabia: Cross-Sectional Study of National e-Referral System Data by Abdullah A Alharbi, Nawfal A Aljerian, Meshary S Binhotan, Hani A Alghamdi, Ali K Alsultan, Mohammed S Arafat, Abdulrahman Aldhabib, Yasser A Alaska, Eid B Alwahbi, Mohammed A Muaddi, Ahmad Y Alqassim, Ronnie D Horner

“…Emergency cases were the most common type of referral overall, followed by routine inpatient and routine outpatient department referrals. …”
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Prevalence and determinants of full vaccination coverage according to the national schedule among children aged 12–35 months in Ghana by Berhan Tekeba, Tadesse Tarik Tamir, Alebachew Ferede Zegeye

“…Abstract Universal immunization of children against common vaccine-preventable diseases is crucial in reducing infant and child morbidity and mortality. …”
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Rock breaking regularity of layered rock mass blasting under the influence of different resistance lines by Jianxin YU, Pengzhan MENG, Xin ZHANG, Zhenzhen LI

“…Layered rock is a common geological structure of underground engineering construction, drilling and blasting method construction in layered rock is manifested in poor blasting and shaping effect, serious phenomenon of over and under excavation, uneven vibration propagation and other problems. …”
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Intracranial pressure monitoring in patients with spontaneous onset of orthostatic headache by Linda D’Antona, Sanjay Cheema, Dwij Mehta, Fion Bremner, Laurence Dale Watkins, Ahmed Kassem Toma, Manjit Singh Matharu

“…The only clinical feature that was more common in patients with abnormal ICP compared to patients with normal ICP results was audiovestibular disturbance, namely aural fullness or muffled hearing (67% versus 17%, p = 0.015). …”
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Uji Daya Hambat Air Perasan Buah Jeruk Nipis (Citrus aurantifolia s.) Terhadap Pertumbuhan Bakteri Staphylococcus Aureus Secara In Vitro by Abdul Razak, Aziz Djamal, Gusti Revilla

“…<br />Abstract Lime (Citrus aurantifolia S.) is kind of family’s herbal medicine, most using in the community is widely used as a traditional herb. The most common used part is the lime fruit squeeze with one of the function is used for removing acne and wound healing to prevent the form of abscess. …”
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Les quais nos 1, 12 et 13 du port romain de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) by Xavier Favreau, Nicolas Ménez

“…Their facades, built following the model of a timber framework system, bear witness to a process rarely attested to for the Roman world in a harbor context. Their state of preservation is remarkable and despite varying degrees of legibility from one box to another, it has allowed for the observation of an entire series of traces left by the carpenters and for the reconstruction of the operational chain of construction for the docks. …”
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Efficacy and safety of acupuncture monotherapy or combined with pelvic floor muscle training for female stress urinary incontinence: a systematic review and meta-analysis by Tong Jiang, Zhi-Yu Dong, Ying Shi, Yang-Qing Zhou, Hong-Bin Zhang, Yi Gong

“…Pelvic floor muscle training (PFMT) is a common physical therapy for SUI, but has low adherence and its long—term effectiveness is uncertain. …”
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