Safety profiles of IDH inhibitors: a pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database by Ximu Sun, Han Zhou, Yanming Li, Yanhui Luo, Qixiang Guo, Yixin Sun, Chenguang Jia, Bin Wang, Maoquan Qin, Peng Guo

“…The median time to onset was 26–31 days for ivosidenib and enasidenib. AML was the most common indication in the differentiation syndrome reports. …”
Get full text

Bacteria-specific modified nucleoside is released and elevated in urine of patients with bacterial infections by Ryosuke Yamamura, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko, Keiichi Yamamoto, Koki Matsushita, Miho Shimamura, Akihiro Kunisawa, Korin Sakakida, Takeshi Chujo, Masataka Adachi, Yutaka Kakizoe, Yuichiro Izumi, Takashige Kuwabara, Masashi Mukoyama, Kazuhito Tomizawa

“…In this study, we performed liquid chromatography-mass spectroscopy (LC-MS) analysis of modified nucleosides from the RNA of 23 pathogenic bacteria, revealing 2-methyladenosine (m2A) as a common bacteria-specific modified nucleoside detected in all bacterial RNAs. …”
Get full text

Impact of social media interventions and tools among informal caregivers of critically ill patients after patient admission to the intensive care unit: A scoping review. by Stephana J Cherak, Brianna K Rosgen, Mungunzul Amarbayan, Kara Plotnikoff, Krista Wollny, Henry T Stelfox, Kirsten M Fiest

“…., Text Messaging, Web Camera) were the most commonly used social media tool (n = 17), followed by social networking sites (e.g., Facebook, Instagram) (n = 6), and content communities (e.g., YouTube, SlideShare) (n = 5). …”
Get full text

High Prevalence but Insufficient Treatment of Iron-Deficiency Anemia in Patients with Inflammatory Bowel Disease: Results of a Population-Based Cohort by Claudia Ott, Anne Liebold, Angela Takses, Ulrike G. Strauch, Florian Obermeier

“…Iron-deficiency anemia is described to be a common problem in patients with inflammatory bowel disease (IBD), which is frequently associated with a reduced quality of life. …”
Get full text

Identification of major hemorrhage in trauma patients in the prehospital setting: diagnostic accuracy and impact on outcome by Nigel R M Tai, Evangelia Kyrimi, Jared M Wohlgemut, Zane B Perkins, William Marsh, Michael Christian, Erhan Pisirir, Rebecca S Stoner, Thomas Hurst

“…Background Hemorrhage is the most common cause of potentially preventable death after injury. …”
Get full text

The Impact of Pelvic Floor Muscle Strengthening on the Functional State of Women Who Have Experienced OASIS After Childbirth by Atėnė Simanauskaitė, Justina Kačerauskienė, Dalia Regina Railaitė, Eglė Bartusevičienė

“…One year after initial consultation, gas incontinence was also more significantly common in the case group (<i>p</i> = 0.037). <i>Conclusions:</i> This study found that PFM strengthening exercises significantly improved pelvic floor function in women who experienced OASIS two years after delivery. …”
Get full text

Effectiveness of Digital Mental Health Interventions in the Workplace: Umbrella Review of Systematic Reviews by Gillian Cameron, Maurice Mulvenna, Edel Ennis, Siobhan O'Neill, Raymond Bond, David Cameron, Alex Bunting

“…AMSTAR-2 was used to complete a quality assessment of the reviews, and the results were critically low for 7 literature reviews and low for the other 7 literature reviews. The most common types of digital intervention studied were cognitive behavioral therapy, mindfulness/meditation, and stress management followed by other self-help interventions. …”
Get full text

Therapeutic Effect of Human Umbilical Cord Mesenchymal Stem Cells at Various Passages on Acute Liver Failure in Rats by Yongting Zhang, Yuwen Li, Wenting Li, Jie Cai, Ming Yue, Longfeng Jiang, Ruirui Xu, Lili Zhang, Jun Li, Chuanlong Zhu

“…Previous studies have shown that the concentration of hepatocyte growth factor (HGF) in the injured liver was significantly increased. HGF is commonly known as the ligand of c-Met. The level of c-Met in hUC-MSCs as detected by Western blotting indicated that at a higher passage number, there is a decrease in c-Met. …”
Get full text

Conocimiento y uso de anticonceptivos entre los jóvenes mexicanos. El papel del género by Irene Casique

“…No obstante, cuando se incorporan al análisis elementos proPios de la relación de noviazgo y secircunscribe el análisis a la frecuencia de uso del condón en las relaciones sexuales con la pareja actual, pierden relevancia los factores objetivos y cobran significancia ciertos elementos más subjetivos propios de la relación: la diferencia de edad con la pareja (Para hombres y mujeres), la duración del noviazgo (Para las mujeres), quién decide cuándo y cómo tener sexo (Para los hombres), el apoyo que ofrece la pareja (sólo los hombres), la actitud hacia los roles de género (en el caso de los hombres), y la presen¬cia de violencia emocional (Para los hombres) y de violencia física.…”
Get full text

Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study by Giorgio Bedogni, Roberto Berni Canani, Laura Carucci, Rita Nocerino, Serena Coppola, Pasqualina Capasso, Veronica Giglio

“…Background We aimed at identifying the factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies (non-IgE-GIFA), a group of common paediatric conditions including food protein–induced: enteropathy (FPE), allergic proctocolitis (FPIAP), enterocolitis syndrome (FPIES), and motility disorders (FPIMD).Methods Prospective multicentre cohort study involving paediatric patients (both sexes, aged ≤14 y) with non-IgE-GIFA diagnosed and followed for 24 months at a Tertiary Centre for Paediatric Allergy, Gastroenterology and Nutrition. …”
Get full text

Human phospholipases A2: a functional and evolutionary analysis by I. I. Turnaev, M. E. Bocharnikova, D. A. Afonnikov

“…Phylogenetic analysis showed that a common origin can be established only for secretory PLA2s (G1, G2, G3, G5, G10 and G12). …”
Get full text

Red blood cell indices in different hemoglobinopathies: A cross-sectional study in Eastern India by Ayandip Nandi, Manas Talukdar, Saikat Bhattacharya, Susruta Sen, Supratik Biswas, Kuntal Roy

“…Introduction: Beta thalassemia and hemoglobin (HbE)-related hemoglobinopathies are common public health problems in developing countries. …”
Get full text

Adaptation of global primary production model to the Greenland Sea conditions: parameterization and monitoring for 1998-2022 by Aleksandra Cherkasheva, Rustam Manurov, Piotr Kowalczuk, Alexandra N. Loginova, Monika Zabłocka, Astrid Bracher, Astrid Bracher

“…As a baseline, we chose the commonly used global primary production model and tested it with different combinations of empirical relationships and input data. …”
Get full text

Assessing the Adherence of ChatGPT Chatbots to Public Health Guidelines for Smoking Cessation: Content Analysis by Lorien C Abroms, Artin Yousefi, Christina N Wysota, Tien-Chin Wu, David A Broniatowski

“…About half of the responses included the recommendation to consider using nicotine replacement therapy (52.7%), the recommendation to seek out social support from friends and family (55.6%), and information on how to deal with cravings when quitting smoking (44.4%). The least common was information about considering the use of non–nicotine replacement therapy prescription drugs (14.1%). …”
Get full text

Motor Learning Deficits in a Neonatal Mouse Model of Hypoxic-Ischemic Injury by Maria Marlicz, Weronika Matysik, Emily Zucker, Sarah Lee, Hannah Mulhern, Jennifer Burnsed

“…Background/Objectives: Motor deficits following neonatal brain injury, from cerebral palsy to subtle deficits in motor planning, are common yet underreported. Rodent models of motor deficits in neonatal hypoxia–ischemia (HI) allow improved understanding of the underlying mechanisms and neuroprotective strategies. …”
Get full text

Effects of Nutritional Strategies on Glucose Homeostasis in Gestational Diabetes Mellitus: A Systematic Review and Network Meta-Analysis by Shixiao Jin, Liyan Sha, Jianli Dong, Jing Yi, Yang Liu, Zhongxian Guo, Bing Hu

“…Gestational diabetes mellitus (GDM) is one of the most common complications of pregnancy, and nutritional therapy is the basis of GDM treatment. …”
Get full text

Hospital attendance, malaria prevalence and self-medication with an antimalarial drug before and after the start of COVID-19 pandemic in a sentinel site for malaria surveillance in... by Denise Patricia Mawili-Mboumba, Fanny Bertrande Batchy Ognagosso, Noé Patrick M’Bondoukwé, Jacques Mari Ndong Ngomo, Bridy Chesly Moutombi Ditombi, Ahmed Adissa Agbanrin, Tatiana Nymane, Bedrich Pongui Ngondza, Reinne Moutongo Mouandza, Coella Joyce Mihindou, Dimitri Ardin Mabika Moussavou, Ornella Anaïse Mbang Nguema, Marielle Karine Bouyou-Akotet

“…Previous self-medication was more common during the COVID-19 period compared to the COVID-19 one (aOR = 2.15 [1.91–2.42]) (p < 0.01). …”
Get full text

Evaluation of the Effectiveness of Soil Improvement Measures in Apple Orchards on the Loess Plateau: A Meta-Analysis by DUAN Shunxia, LIU Jiayuan, ZHAO Hongxiang, LI Yangyang

“…[Objective] Soil acidification, structure and fertility degradation and poor water-holding capacities are common problems in the apple orchard on the Loess Plateau, effective soil improvement techniques are crucial for enhancing soil quality, and promoting the healthy and sustainable development of the orchards. …”
Get full text

Longitudinal impact of past-year reproductive coercion on contraceptive use dynamics in Sub-Saharan Africa: evidence from eight population-based cohortsResearch in context by Shannon N. Wood, Haley L. Thomas, Georges Guiella, Rosine Mosso, Peter Gichangi, Simon P.S. Kibira, Fredrick Makumbi, Pierre Z. Akilimali, Funmilola M. OlaOlorun, Elizabeth Omoluabi, Michele R. Decker

“…Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission.…”
Get full text

The Concurrent Validity and Reliability of Single Leg Squat Among Physically Active Females with and without Dynamic Knee Valgus by Nazatul Izzati Jamaludin, Farhah Nadhirah Aiman Sahabuddin, Nur Syahmina Rasudin, Shazlin Shaharudin

“…# Background The single leg squat (SLS) motion imitates various maneuvers in sports. It is commonly used as a functional test for the lower limb. …”
Get full text