Conjunctival scarring in trachoma is associated with the HLA-C ligand of KIR and is exacerbated by heterozygosity at KIR2DL2/KIR2DL3. by Chrissy H Roberts, Sandra Molina, Pateh Makalo, Hassan Joof, Emma M Harding-Esch, Sarah E Burr, David C W Mabey, Robin L Bailey, Matthew J Burton, Martin J Holland

“…<h4>Background</h4>Chlamydia trachomatis is globally the predominant infectious cause of blindness and one of the most common bacterial causes of sexually transmitted infection. …”
Get full text

Dynamic Monitoring of sTREM-1 and Other Biomarkers in Acute Cholangitis by Jiahui Jiang, Xiaolei Wang, Tongtong Cheng, Mingyue Han, Xinxin Wu, Haitong Wan, DaojunYu

“…Background. Sepsis is a common complication of acute cholangitis (AC), which is associated with a high mortality rate. …”
Get full text

Research on leakage and diffusion behavior of hydrogen doped natural gas in integrated pipeline corridors based on data drive by Xiaolong Gong, Hua Li, Cheng Li, Mingyue Kou, Lingxu Kong, Hongcheng Liu

“…Abstract With the wide application of hydrogen-doped natural gas (HBNG) in end users, laying pipelines in urban, comprehensive pipe corridors has become increasingly common. However, the leakage and diffusion of hydrogen-doped natural gas in confined or semi-confined spaces (e.g., utility corridors) can pose a severe safety hazard, as methane and hydrogen gas mixtures have a higher risk of explosion. …”
Get full text

Implications of cytokine genes polymorphisms in Jordanian patients with obsessive compulsive disorder by Ahmad M. Khalil, Manal W. Khrais, Khaled M. Al-Qaoud, Mohamad Y. Al Ta’any

“…Abstract Background Obsessive–compulsive disorder (OCD) is a common and often highly debilitating chronic neuropsychiatric condition. …”
Get full text

Класифікація міжнародних злочинів by V. V. Nalutsyshyn, V. V. Nalutsyshyn, R. V. Nalutsyshyn

“…Наголошено, що основна розбіжність між національним законодавством та загальновизнаними складами міжнародних злочинів в міжнародному кримінальному праві полягає у відсутності криміналізації злочину проти людяності та відсутності інституту командної відповідальності (chief of command). Зроблено висновок, що основним законодавчим кроком є приведення національного кримінального законодавства України у повну відповідність до вимог Римського статуту Міжнародного кримінального суду для забезпечення справедливого, необхідного і невідворотного покарання осіб, які вчиняють міжнародні злочини. …”
Get full text

Prognosis Analysis and Validation of Fatty Acid Metabolism-Related lncRNAs and Tumor Immune Microenvironment in Cervical Cancer by Xiaolin Lang, Changchang Huang, Hongyin Cui

“…Cervical cancer (CC) is the third most common carcinoma and the fourth leading cause of cancer-associated mortality in women. …”
Get full text

Modelling the impact of environmental responsibility on the development of enterprises by M. Pinskaya, O. Meleshchenko, O. Kovalchuk, O. Karpenko, E. Kompanets

“…This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. …”
Get full text

Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53. by Kenneth Y Wertheim, Robert Chisholm, Paul Richmond, Dawn Walker

“…Neuroblastoma is the most common extra-cranial solid tumour in children. Over half of all high-risk cases are expected to succumb to the disease even after chemotherapy, surgery, and immunotherapy. …”
Get full text

COVID-19 Mortality in Children: A Referral Center Experience from Iran (Mofid Children’s Hospital, Tehran, Iran) by Shahnaz Armin, Seyed Alireza Fahimzad, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaiee, Noushin Marhamati, Seyyedeh Narjes Ahmadizadeh, Azita Behzad, Seyedeh Masumeh Hashemi, Saeed Sadr, Maryam Rajabnejad, Mahnaz Jamee, Abdollah Karimi

“…In addition, the most common reasons for death in our study were related to respiratory and multiorgan failure. …”
Get full text

Metaverse Clinic for Pregnant Women With Subclinical Hypothyroidism: Prospective Randomized Study by Yuanyuan Zheng, Yizhen Chen, Yan Chen, Liang Lin, Ting Xue, Chuhui Chen, Junping Wen, Wei Lin, Gang Chen

“…Subclinical hypothyroidism (SCH) is the most common thyroid disorder during pregnancy and is frequently associated with adverse pregnancy outcomes. …”
Get full text

Chronique d’un non-lieu: le marxisme en Grande-Bretagne by Emmanuel Jousse

“…Un examen plus approfondi de la question permet en réalité de mesurer l’importance de chronologies différenciées qui, toutes ensemble, empêchent le marxisme de devenir le discours commun du socialisme anglais. Les idées de Marx peinent à s’implanter parce qu’elles sont assez peu adaptées aux réalités politiques et sociologiques du monde ouvrier anglais, qui dispose déjà d’autres cadres d’interprétation pour expliquer son expérience historique. …”
Get full text

A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in... by Thomas R. Moench, Lakshmi Botta, Brian Farrer, Jason D. Lickliter, Hyunah Kang, Yoona Park, Cheolmin Kim, Marshall Hoke, Miles Brennan, Morgan D. McSweeney, Zachary Richardson, John B. Whelan, Jong Moon Cho, Soo Young Lee, Frances Faurot, Jeff Hutchins, Samuel K. Lai

“…Army Medical Research and Development Command (W81XWH-15-9-0001) and regdanvimab was provided by Celltrion, Inc.…”
Get full text

Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis by Yafei Zhao, Yuanyuan Qi, Xinran Liu, Yan Cui, Zhanzheng Zhao

“…Systemic lupus erythematosus (SLE) has become increasingly common in the clinic and requires complicated evidence of both clinical manifestations and laboratory examinations. …”
Get full text

mRNA-lncRNA gene expression signature in HPV-associated neoplasia and cervical cancer by E. D. Kulaeva, E. S. Muzlaeva, E. V. Mashkina

“…Only two genes were observed to be differentially expressed in the “neoplasia vs. control” comparison. The search for common genes among the most strongly differentially expressed genes among all comparison groups resulted in the identification of an expression signature consisting of the CCL20, CDKN2A, CTCFL, piR-55219, TRH, SLC27A6 and EPHA5 genes. …”
Get full text

How does individualised physiotherapy work for people with low back pain? A Bayesian Network analysis using randomised controlled trial data. by Bernard X W Liew, Jon J Ford, Marco Scutari, Andrew J Hahne

“…Sequences of variables in the Bayesian Network showed the most common direct and indirect recovery pathways followed by participants with low back pain receiving individualised physiotherapy versus advice.…”
Get full text

LA FORMAZIONE PLURILINGUE DI OPERATORI DELLA RISTORAZIONE E DEL TURISMO: ASPETTI METODOLOGICI E COMPITI DIDATTICI PER LA TELECOLLABORAZIONE by Emanuela Paone

“…Inoltre, mira a discutere le scelte metodologiche che hanno guidato la creazione di un syllabus task-based per la formazione linguistica in contesti professionali e a fornire strumenti operativi per stimolare i docenti a sperimentare in classe attività comunicative autentiche e aperte al plurilinguismo. L’elaborazione del syllabus è stata guidata dai descrittori di tre referenziali fondamentali: il Quadro Comune Europeo di Riferimento per le Lingue (QCER), il Référentiel de Compétences de Communication Plurilingue en Intercompréhension (REFIC), e il Cadre de Référence pour les Approches Plurielles des Langues et des Cultures (CARAP). …”
Get full text

Evaluating Medical Students' Perspectives on the CBME Curriculum: A Qualitative Exploration of Curriculum Structure, Pedagogical Approaches, and Educational Integration by Amit Kumar Kamboj, Mudit Sharma, Rashmi Ramanathan, Vivin Vincent, Jeevithan Shanmugam

“…Recommendations for new curriculum elements included mental health support, interactive learning formats, and direct patient exposure. Common challenges cited were the extensive logbook requirements and lengthy assessments. …”
Get full text

Antimicrobial Resistance and Biofilm-Forming Ability in ESBL-Producing and Non-ESBL-Producing <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> Isolated from Canine Urinary... by Alessia Facchin, Joel Filipe, Irene Mauri, Filippo Tagliasacchi, Guido Grilli, Tiziana Vitiello, Gabriele Ratti, Laura Musa, Martina Penati, Paola Scarpa, Stefania Lauzi

“…<i>E. coli</i> was confirmed as the most commonly identified urinary isolate in dogs. <b>Conclusions</b>: The high presence of ESBL producers and MDR in <i>K. pneumoniae</i> suggests mandatory in vitro susceptibility testing in the presence of this bacterium in dogs with UTI. …”
Get full text

Thrombophilia screening in women with recurrent first trimester miscarriage: is it time to stop testing? – a cohort study and systematic review of the literature by Hassan Shehata, Ranjit Akolekar, Amanda Ali, Mariane Silva-Edge, Shahla Haroon, Abdullatif Elfituri, Radhika Viswanatha, Haider Jan

“…All patients had three or more first trimester miscarriages and a full thrombophilia screen.Results The overall prevalence of thrombophilia in our study population is 9.2% (106/1155) with 8.1% (94/1155) of cases positive for inherited thrombophilia, which is similar to the general population; Factor V Leiden (4.9%; 57/1155) and prothrombin gene mutation (2.9%; 34/1155) were the most common inherited thrombophilias, while only 1% (12/1155) tested positive for acquired thrombophilia. …”
Get full text

Pregnancy Outcomes among Patients with Sickle Cell Disease in Brazzaville by F. O. Galiba Atipo Tsiba, C. Itoua, C. Ehourossika, N. Y. Ngakegni, G. Buambo, N. S. B. Potokoue Mpia, A. Elira Dokekias

“…Sickle cell disease (SCD) is one of the most common genetic diseases in the world. It combines, in its homozygous form, chronic hemolytic anemia, vasoocclusive complications, and susceptibility to infections. …”
Get full text