The global, regional, and national patterns of change in the burden of bacterial pyoderma from 1990 to 2019 and the forecast for the next decade by Hao Wang, Zihao Bai, Chong Shen, Jiaxi Kou, Yanqing Zhu, Huaxia Xie, Chen Chen, Ran Mo

“…Abstract Pyoderma, commonly known as impetigo, is a bacterial skin infection causing pus formation, prevalent globally, especially in resource-poor areas. …”
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First-in-human phase 1 study of the arginase inhibitor INCB001158 alone or combined with pembrolizumab in patients with advanced or metastatic solid tumours by Michael Smith, Aung Naing, Todd Bauer, Kyriakos P Papadopoulos, Osama Rahma, Elena Garralda, Glenn J Hanna, Michael J Pishvaian, Xuejun Chen, Sven Gogov, Omar Saavedra, Howard Kallender, LuLu Cheng, Emil Kuriakose

“…INCB001158 exposure was similar between groups (median, 56 days (monotherapy); 84 days (combination)). 49 patients (45.8%) on monotherapy and 76 (51.7%) on combination therapy experienced grade ≥3 treatment-emergent adverse events (AEs). The most common INCB001158-related AEs were fatigue (n=10/107 (9.3%)) and nausea (n=10/107 (9.3%)) with monotherapy and diarrhoea (n=24/147 (16.3%)) and fatigue (n=22/147 (15.0%)) with combination therapy. …”
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Longitudinal Invariance Testing Of The Knee Injury Osteoarthritis Outcome Score For Joint Replacement Scale (KOOS-JR) by Alexandra Dluzniewski, Caleb Allred, Madeline P Casanova, Jonathan D Moore, Adam C Cady, Russell T Baker

“…# Background The Knee Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR) is a seven-item patient reported outcome measure used to assess perceived knee health. Though commonly used, the longitudinal psychometric properties of the KOOS-JR have not been established and further characterization of its structural validity and multi-group invariance properties is warranted…”
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How Reliable Is Endoscopic Scoring of Postoperative Recurrence in Crohn Disease?: A Systematic Review and Meta-Analysis by Eline M. L. van der Does de Willebois, MD, Vittoria Bellato, MD, Marjolijn Duijvestein, MD, PhD, Susan van Dieren, MD, PhD, Silvio Danese, MD, PhD, Pierpaolo Sileri, MD, PhD, Christianne J. Buskens, MD, PhD, Andrea Vignali, MD, PhD, Willem A. Bemelman, MD, PhD

“…This study aims to assess the variation in endoscopic recurrence (ER) rates in patients after ICR for CD using the most commonly used classification systems, the Rutgeerts score (RS) and modified Rutgeerts score (mRS) classifications. …”
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Predicting purulent meningitis in very preterm infants: a novel clinical model by Xiaowei Sun, Rui Jing, Yang Li

“…Abstract Background Purulent meningitis (PM) is a commonly encountered infectious condition in newborns, which unfortunately can result in infant mortality. …”
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Virulence diversity of the yellow rust pathogen population in Dagestan by E. I. Gultyaeva, E. L. Shaydayuk, R. E. Smirnova, K. M. Abdullaev, K. U. Kurkiev

“…The Dagestan collection demonstrated high genetic diversity. Common phenotypes were identified on cv. ‘Graf’ in 2021 and 2020. …”
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Reliability of Goniometric Techniques for Measuring Hip Flexor Length Using the Modified Thomas Test by Kira Eimiller, Emma Stoddard, Briana Janes, Mason Smith, Andrew Vincek

“…# Background The modified Thomas test (MTT) is commonly used to assess the flexibility of hip musculature, including the iliopsoas, rectus femoris, and tensor fascia latae. …”
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Acquired hypothyroidism, iodine status and hearing impairment in adults: A pilot study. by Tereza Grimmichova, Ludmila Verespejova, Zuzana Urbaniova, Martin Chovanec, Martin Hill, Radovan Bilek

“…However, some forms of hearing impairment, mostly mild, were very common in both studied groups.…”
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Prevalence of ESBL resistance genes and fecal carriage of multidrug-resistant Pseudomonas aeruginosa isolates from patients with chronic kidney disease at the Laquintinie Hospital... by Ballue S.T. Dadjo, Armelle T. Mbaveng, Michael F. Kengne, Ornella D. Tsobeng, Giresse D.T. Fonjou, Victor Kuete

“…ESBL resistance genes were more common in CKD patients (72.22 %) compared to patients without CKD (27.78 %). …”
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Artificial Visual System for Stereo-Orientation Recognition Based on Hubel-Wiesel Model by Bin Li, Yuki Todo, Zheng Tang

“…However, due to the recognition process of high-dimensional spatial information commonly occurring in high-order cortex, we still know little about the mechanisms underlying stereo-orientation selectivity and lack a modeling strategy. …”
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Are Functional Performance Test Scores Better When Compared to Baseline or Contralateral Limb Scores Following LE Injury in Adolescent Athletes? by Edward Jones, Jessica Jochum, Hannah Corn, Michaela O'Brien, Melissa Parks, Jamal Armoush, Amanda Annee

“… # Hypothesis/Purpose This study aimed to compare common functional performance test scores from injured athletes at the time of release to RTP to both preseason baseline scores and to the contralateral limb. …”
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The sphingosine‐1‐phosphate signaling pathway (sphingosine‐1‐phosphate and its receptor, sphingosine kinase) and epilepsy by Lin Wang, Qingxia Kong, Xinyi Leng, Howan Leung, Yang Li

“…Abstract Epilepsy is one of the common chronic neurological diseases, affecting more than 70 million people worldwide. …”
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Factors Affecting the Presence of Renal Cortical Cysts in Kidney Donors by Sevim Nuran Kuşlu Çiçek, Amil Huseynov

“…Conclusion: The study confirms that SRCs are the most common renal cyst type and are more frequently observed in the elderly population. …”
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Annotation and characterization of immunoglobulin loci and CDR3 polymorphism in water buffalo (Bubalus bubalis) by Yunlan Deng, Fengli Wu, Fengli Wu, Qianqian Li, Lidie Yao, Chengzhi Yang, Long Ma, Xinsheng Yao, Jun Li

“…Repertoire diversity, gene usage, and clonal frequencies were analyzed using the Immunarch R package.ResultsThe IgH locus spans approximately 667 kb on chromosome 20, containing two D-J-C clusters, 54 VH genes, 10 DH genes, 8 JH genes, and 9 CH genes. …”
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Modern classification and molecular-genetic aspects of osteogenesis imperfecta by A. R. Zaripova, R. I. Khusainova

“…Osteogenesis imperfecta (imperfect osteogenesis in the Russian literature) is the most common hereditary form of bone fragility, it is a genetically and clinically heterogeneous disease with a wide range of clinical severity, often leading to disability from early childhood. …”
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Tourism planning and development: The case of Portugal’s Norte region by Ana Paula Lopes, Filomena Soares

“…Comparing the forecast values in terms of overnight stays, tourists and revenue set by PENT, the reality showed that the results were a little bit far from the expected; however, the findings confirm the common perception that Portugal’s Norte region is still experiencing a trend towards growth as a tourist destination.…”
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Clinical and Histopathological Characteristics of Acquired Inflammatory Blaschko-Linear Disorders by Nikhil Mehta, Binod K. Khaitan, M. Ramam, Neetu Bhari, Gomathy Sethuraman, Manoj K. Singh

“…Results: Out of 99 patients, linear lichen planus (n = 47), linear morphea (n = 31), and lichen striatus (n = 9) were observed most commonly. Skin lesions were present in multiple lines in 52 (52.5%). …”
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Quality of Life as Medicine: A Pilot Studyof Patients with Chronic Illness and Pain by Soren Ventegodt, Joav Merrick, JØrgen Anderson

“…As far as diagnoses were concerned, the group was inhomogeneous. Common for the group was a low QoL, poor quality of working life QWL, and numerous health problems. …”
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Safety and Efficacy of Subcutaneous Rituximab in Previously Untreated Patients with CD20+ Diffuse Large B-Cell Lymphoma or Follicular Lymphoma: Results from an Italian Phase IIIb S... by Mario Petrini, Gianluca Gaidano, Andrea Mengarelli, Ugo Consoli, Armando Santoro, Anna Maria Liberati, Marco Ladetto, Vincenzo Fraticelli, Attilio Guarini, Donato Mannina, Paola Ferrando, Paolo Corradini, Pellegrino Musto, Caterina Stelitano, Dario Marino, Andrea Camera, Marco Murineddu, Roberta Battistini, Giuseppe Caparrotti, Mauro Turrini, Luca Arcaini, Simone Santini, Manuela Cerqueti, Andres J. M. Ferreri, Nicola Cantore, Alessandro Inzoli, Giovanni Cardinale, Benedetto Ronci, Giorgio La Nasa, Stefano Massimi, Gianfranco Gaglione, Valentina Barbiero, Maurizio Martelli

“…Neutropenia (14 patients, 8.9%) was the most common treatment-related TEAE. Two patients with DLBCL (2.8%) and 6 with FL (7.0%) discontinued rituximab due to TEAEs. 65.2% and 69.7% of patients with DLBCL and 67.9% and 73.6% of patients with FL had complete response (CR) and CR unconfirmed, respectively. …”
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Empowerment key factors in shaping women's awareness of household waste management by D. Asteria, J. Haryanto

“…This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. …”
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