Single-cell multiomics reveal divergent effects of DNMT3A- and TET2-mutant clonal hematopoiesis in inflammatory response by Wazim Mohammed Ismail, Jenna A. Fernandez, Moritz Binder, Terra L. Lasho, Minsuk Kim, Susan M. Geyer, Amelia Mazzone, Christy M. Finke, Abhishek A. Mangaonkar, Jeong-Heon Lee, Liguo Wang, Kwan Hyun Kim, Vernadette A. Simon, Fariborz Rakhshan Rohakthar, Amik Munankarmy, Seul Kee Byeon, Susan M. Schwager, Jonathan J. Harrington, Melissa R. Snyder, Keith D. Robertson, Akhilesh Pandey, Eric D. Wieben, Nicholas Chia, Alexandre Gaspar-Maia, Mrinal M. Patnaik

“…Abstract: DNMT3A and TET2 are epigenetic regulator genes commonly mutated in age-related clonal hematopoiesis (CH). …”
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The process of pain assessment in people with dementia living in nursing homes: a scoping review by Caroline Kreppen Overen, Maria Larsson, Adelheid Hummelvoll Hillestad, Ingela Karlsson, Siren Eriksen

“…Background: Pain is a common symptom in people with dementia living in nursing homes, but cognitive impairment, including language and communication difficulties, challenges pain assessment and the ability to self-report pain. …”
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Determination of synbiotic mango fruit yogurt and its bioactive peptides for biofunctional properties by Jagrani Minj, Shilpa Vij

“…Fortification of yogurt with different food components, including fruit pulp, is a common practice to make it more palatable and healthier. …”
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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…Routine clinical data, including general patient demographics, diagnosis, treatment and outcomes, were collated and pseudonymised.Setting Patients diagnosed with uterine sarcoma in the UK National Health Service between 1 January 2008 and 31 December 2017 were identified from electronic records.Participants A total of 406 patients from eight centres were eligible for inclusion.Results The median age at diagnosis was 56 years, with leiomyosarcoma the most common diagnosis (54.4%). The majority (57.9%) were diagnosed at the International Federation of Gynecology and Obstetrics stage I, with 19.7% diagnosed at stage IV. …”
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Polysomnographic features of children with obesity: body mass index predict severe obstructive sleep apnea in obese children? by Rungrat Sukharom, Prakarn Tovichien, Kanokporn Udomittipong, Pinyapach Tiamduangtawan, Wattanachai Chotinaiwattarakul

“…Conclusion Severe OSA is common in children with obesity; thus, we recommend screening children with obesity and a BMI greater than 29.2 kg/m2 for severe OSA.…”
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Assessing health governance across countries: a scoping review protocol on indices and assessment tools applied globally by Kun Tang, Liyuan Zhang, Aidan Huang, Yuling Lin, Jingwen Dong, Qiwei He

“…This scoping review aims to review the existing multicountry indices and assessment tools applied globally with measurable indicators assessing health governance; summarise their differences and commonalities; identify the lessons learnt through analysis of their advantages and gaps; and evaluate the feasibility and necessity to establish a new index or consensus framework for assessing global health governance.Methods and analysis This scoping review protocol follows Arksey and O’Malley’s methodological framework, the Joanna Briggs Institute guidelines and the Preferred Reporting Items for Systematic Reviews and Meta-analyses methodology for scoping reviews. …”
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AOZORA: long-term safety and joint health in paediatric persons with haemophilia A without factor VIII inhibitors receiving emicizumab – protocol for a multicentre, open-label, pha... by Seitaro Yoshida, Masashi Taki, Hideyuki Takedani, Midori Shima, Keiji Nogami, Azusa Nagao, Haruko Yamaguchi-Suita, Yui Kyogoku, Akira Ishiguro, Kaoru Kitsukawa

“…Introduction Persons with haemophilia A (PwHA) commonly experience regular bleeding into joints, which may result in joint damage and complications such as degenerative arthritis. …”
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Comparing the effects of intercostal and subcostal flank incision on post-operative pain and incisional hernia or bulge in patients undergoing open kidney surgery: A randomized cli... by Alireza Abdi, Behzad Imani, Seyed Habibollah Mousavibahar, Salman Khazaei, Shima Bahrami Jalal

“…BACKGROUND: Flank incision, a common approach in kidney surgery, has several types. …”
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The Present and the Future of the Special Relationship: The Debate in the United States and the United Kingdom by A. O. Mamedova

“…Particular attention is paid to the House of Commons Foreign Affairs Committee’s reports on UK–U.S. relations and the Report of the Iraq Inquiry (Chilcot report). …”
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Jean-Baptiste Camps, La Chanson d’Otinel. Édition complète du corpus manuscrit et prolégomènes à l’édition critique by Jean-Baptiste Camps

“…It aims at overcoming the debate between “New” and Traditional Philology, based on the common errors method or of Bedierist inspiration, to place itself in the perspective of a “Fourth Way” and of an edition “oriented towards the tradition”.Digital scholarly editing and Digital Philology techniques are used in order to provide a full edition of the manuscript corpus, with “layered” transcriptions that give access to different representations and to the graphic system of all witnesses. …”
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Examining the structure of images in the sonnets of the return period by Mostafa Mirdar Rezaei, Farzad Baloo

“…The current research, which is written in a quantitative-statistical way and with a stylistic approach and by examining the geometry of the images of the sonnets of six prominent poets of the return period (Mushtaq Esfahani, Hatef Esfahani, Azar Bigdeli, Soroush Esfahani, Sabai Kashani and Fethullah Khan Shibani), tries to avoid common generalizations regarding the similarity of the poetry of the poets of the period of return to the poetry of the poets of the previous styles, by presenting accurate statistics and It is clear about the amount of use of individual and combined artistic structures by each poet, apart from determining the level and quality of the structure of the images in terms of simplicity or complexity, by comparing the geometry of the images of the sonnets of the poets of this literary school with the structure of the images of the Iraqi and Indian style poets. …”
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Biological peculiarities and cultivation of groundnut (a review) by N. V. Kishlyan, V. D. Bemova, T. V. Matveeva, V. A. Gavrilova

“…The modern phylogenetic system of the genus Arachis L. includes 79 wild species and one cultivated species of common peanut (A. hypogaea L.). Diploid species contain 2n = 20 chromosomes of the A, B or D genome, tetraploids have A and B genomes. …”
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Disrupted Regional Spontaneous Neural Activity in Mild Cognitive Impairment Patients with Depressive Symptoms: A Resting-State fMRI Study by Xiaozheng Liu, Yunhai Tu, Yirou Zang, Aiqin Wu, Zhongwei Guo, Jiawei He

“…Depressive symptoms are common in individuals with mild cognitive impairment (MCI) who have an increased risk of dementia. …”
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Evaluation of laboratory findings indicating pancreatitis in healthy lean, obese, and diabetic cats by Freja K. Jørgensen, Charlotte R. Bjornvad, Birgit Krabbe, Stinna Nybroe, Ida N. Kieler

“…Abstract Background Obesity is a risk factor for diabetes mellitus, which commonly coexists with pancreatitis in cats. However, obesity has not previously been associated with pancreatitis in cats. …”
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Efficacy of Diltiazem for the Control of Blood Pressure in Puerperal Patients with Severe Preeclampsia: A Randomized, Single-Blind, Controlled Trial by Gilberto Arias-Hernández, Cruz Vargas-De-León, Claudia C Calzada-Mendoza, María Esther Ocharan-Hernández

“…Postpartum preeclampsia is a serious disease related to high blood pressure that occurs commonly within the first six days after delivery. …”
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Comparative analysis of acids and temperatures in gelatin extraction from the skin of yellowfin tuna (Thunnus albacares) by Vicky Prajaputra, Sri Agustina, Nadia Isnaini, Agillia Nabila, Hikma Kasih Margolang, Sahra Apriani, Siti Maqfirah

“…Gelatin, a valuable biopolymer, is commonly derived from animal by-products such as fish skin, providing a sustainable alternative to traditional bovine and porcine sources. …”
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What are the lived healthcare experiences of patients with primary sclerosing cholangitis? A community-based qualitative interview study by Sheila Greenfield, Gideon Hirschfield, Jayne Parry, Katherine Arndtz, Madeline Cameron

“…Overcoming the unusual combination of uncertainties that PSC presents was of particular concern to participants; these differ from those observed in more common chronic diseases with established treatment pathways. …”
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Procedural aspects of the crime scene inspection as an investigative (search) activity: some issues for discussion by Y. Yu. Koniushenko

“…The importance of researching the issues raised in the article is due to the fact that in practice, conducting various types of inspections is the most common procedural action aimed at collecting and verifying evidence. …”
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Natural Polymer Derivative-based pH responsive Nanoformulations Entrapped Diketo-tautomers of 5-fluorouracil for Enhanced Cancer Therapy by Anbazhagan Thirumalai, Koyeli Girigoswami, Karthick Harini, Venkatakrishnan Kiran, Pazhani Durgadevi, Agnishwar Girigoswami

“… Background and purpose: Despite significant advancements in cancer therapies, chemotherapeutics continue to be the mainstay for treating cancer patients, with 5-fluorouracil (5-FU) being commonly used for various cancers. However, its limited ability to penetrate cell membranes and its short half-life, caused by rapid metabolism, necessitate frequent administration of high doses to maintain effective therapeutic levels. …”
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Association between the levels of urinary cell cycle biomarkers and non-recovery of renal function among critically ill geriatric patients with acute kidney injury by Li Cheng, Hui-Miao Jia, Xi Zheng, Yi-Jia Jiang, Xin Xin, Wen-Xiong Li

“…The lack of early renal function recovery among geriatric patients with acute kidney injury (AKI) in the intensive care unit (ICU) is a commonly observed and acknowledged poor prognostic factor, especially for older adults. …”
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