A new approach to children’s work that prioritises resilience, well-being and agency: emerging findings from a ‘cash plus’ intervention in Bangladesh by Neil Howard, Keetie Roelen, Giel Ton, Mauricio Espinoza Hermoza, Saklain Al Mamun, Kabita Chowdhury, Taslima Aktar, Lopita Huq

“…They further suggest that case work and community organising act as a beneficial form of social protection and a tool for developing locally appropriate micro-responses to collective problems that commonly impact directly on well-being and indirectly on children’s work. …”
Get full text

Real-world clinical outcome of unresectable locally advanced & de-novo metastatic pancreatic ductal adenocarcinoma: a multicentre retrospective study by Mohamed Aseafan, Ali H. Alfakeeh, Emad Tashkandi, Mervat Mahrous, Mohammed Alghamdi, Bader Alshamsan, Marwan Al-Hajeili, Safwan Bakhsh, Kanan Alshammari, Fahad A. Almugbel, Abdulhameed H. Alfagih, Ahmed Allehebi, Mohamed Montaser, Mohamed Hamdy Elsafty, Khaled Abd Elaziz Elnaghi, Ibrahim Issa, Eesa Bakshi, Sadeem AlSubaie, Bandar AlMutairi, Hoda Mokhtar, Mohamed Aboelatta, Nedal Bukhari, Ali M. Alzahrani, Tusneem Elhassan, Ali Alqahtani, Shouki Bazarbashi

“…FOLFIRINOX was the most common first-line treatment (55.1%), followed by gemcitabine plus nab-paclitaxel (15.1%). …”
Get full text

Individual and Obstetric Risk Factors of Preeclampsia among Singleton Pregnancy in Hospitals of Southern Ethiopia by Kassahun Fikadu Tessema, Feleke Gebremeskel, Firdawek Getahun, Nega Chufamo, Direslgne Misker

“…Preeclampsia is the second most common problem that causes maternal morbidity and complication in low-income countries. …”
Get full text

A patient choice‐driven lifestyle intervention lowers HbA1c in type 2 diabetes: A feasibility study by Nathan R. Weeldreyer, Mindy L. McEntee, Matthew P. Martin, Chong D. Lee, Farshad Fani Marvasti, Glenn A. Gaesser, Rodger Kessler, Siddhartha S. Angadi

“…Abstract Type 2 diabetes (T2D) is a common metabolic disorder in which only 25% of patients meet management targets. …”
Get full text

Self-Perceived Barriers to Pediatric Cancer Care in Sub-Saharan Africa: A Cross-Sectional Multinational Study by Ole Stoeter, Nikolaus C.S. Mezger, Tamara Koenig, Eric Chokunonga, Girum Tessema, Adugna Fekadu Damise, Alda Stevy Makouanzi, Esther Majaliwa, Mahine Ivanga, Bakarou Kamate, Franck Gnahatin, Sarah Nambooze, Ima-Obong A. Ekanem, Toralf Bernig, Biying Liu, Sumit Gupta, Eva Johanna Kantelhardt

“…For radiotherapy, long waiting time and (limited) availability in the country were more commonly barriers (OR, 7.53 [95% CI, 3.38 to 16.78]; OR, 11.11 [95% CI, 2.04 to 60.46], respectively) than for chemotherapy.CONCLUSIONDespite known barriers such as the availability of therapy, our study additionally indicates the importance of the patients' and families' perceptions of the disease and its treatment. …”
Get full text

Prevalence and Characterization of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Isolated in Canadian Hospitals: Results from CANWARD 2007 by Patricia J Baudry, Melissa McCracken, Philippe Lagacé-Wiens, Michael R Mulvey, George G Zhanel, Daryl J Hoban

“…CONCLUSION: CTX-M has become the most common enzyme among both ESBL-producing E coli and K pneumoniae. …”
Get full text

Toxicity Evaluation of a Polyphenolic Extract from Flourensia cernua DC through Artemia Lethality Assay, Hemolytic Activity, and Acute Oral Test by Yulma Lizbeth Aguirre-García, Ainara Castillo-Manzanares, Lissethe Palomo-Ligas, Juan Alberto Ascacio-Valdés, Lizeth Guadalupe Campos-Múzquiz, Sandra Cecilia Esparza-González, Raúl Rodríguez-Herrera, Sendar Daniel Nery-Flores

“…Flourensia cernua DC, commonly known as hojasen or tarbush, is a medicinal plant used in arid regions due to its therapeutic properties, especially in the treatment of gastrointestinal disorders. …”
Get full text

Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial by Fang Chen, Cheng Li, Dongliang Li, Jinxuan Tang, Jiayu Huang

“…Introduction Propofol is a fast-acting intravenous anaesthetic widely used for sedation and anaesthesia in gastrointestinal endoscopy, bronchoscopy, and the induction/maintenance of general anaesthesia in outpatients and inpatients; however, propofol has several undesirable effects, including injection pain, which affects the physical and mental health of patients, and cardiopulmonary depression, characterised by hypotension, bradycardia and apnea, which commonly occur in clinical practice. Ciprofol (HSK3486) is a propofol analogue with good clinical safety, high potency and some advantages over propofol, including lower injection pain and haemodynamic depression in patients undergoing gastroscopy and colonoscopy. …”
Get full text

Blocks identical by descent in the genomes of the indigenous population of Siberia demonstrate genetic links between populations by N. A. Kolesnikov, V. N. Kharkov, K. V. Vagaitseva, A. A. Zarubin, V. A. Stepanov

“…For this, DNA fragments were analyzed, which had been inherited without recombination by each pair of individuals from their recent common ancestor, that is, segments (blocks) identical by descent (IBD). …”
Get full text

Lessons Learned from Van Earthquake in the Context of Urban Environment and Health by Bilge Kalanlar

“…In addition, disaster in our city or in common areas on the point of being prepared, determined winterized tents, container depots should be created to store the offered guaranteed health and needed sleeping bags for staff, food supplies which have available stock opportunities, catalytic stoves, cleaning supplies, portable toilets, kitchen are the most important findings are issued in the context of the urban environment and health.…”
Get full text

Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility by Rosalyn W Sayaman, Masaru Miyano, Eric G Carlson, Parijat Senapati, Arrianna Zirbes, Sundus F Shalabi, Michael E Todhunter, Victoria E Seewaldt, Susan L Neuhausen, Martha R Stampfer, Dustin E Schones, Mark A LaBarge

“…Age-dependent variant responses were common to both lineages, whereas directional changes were almost exclusively detected in luminal epithelia and involved altered regulation of chromatin and genome organizers such as SATB1. …”
Get full text

Pleiotropic Effects of a KCNQ1 Variant on Lipid Profiles and Type 2 Diabetes: A Family-Based Study in China by Xiaowen Wang, Junhui Wu, Yao Wu, Mengying Wang, Zijing Wang, Tao Wu, Dafang Chen, Xun Tang, Xueying Qin, Yiqun Wu, Yonghua Hu

“…The genetic variant rs2237895, located in the Potassium Voltage-Gated Channel Subfamily Q Member 1 (KCNQ1) gene, has been replicated to be associated with type 2 diabetes mellitus (T2DM) susceptibility, but the relationship with lipids is conflicting. Furthermore, the common genetic predisposition to T2DM and lipids was not fully detected. …”
Get full text

Atmospheric cold plasma alters plant traits and negatively affects the growth and development of fall armyworm in rice by Deepak Dilip, Nikitha Modupalli, Md Mahfuzur Rahman, Rupesh Kariyat

“…Abstract Plasma is considered as the fourth state of matter, and atmospheric cold plasma (cold plasma) is a type of plasma consisting of ionized gases containing excited species of atoms, molecules, ions, and free radicals at near room temperature. …”
Get full text

Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Increasing evidence has suggested that NEOs may affect glucose homeostasis, but little research has linked NEOs exposure to gestational diabetes mellitus (GDM), which is the most common disease in pregnancy. We here aimed to investigate the association between NEOs exposure and GDM occurrence. …”
Get full text

Is Topical Tranexamic Acid Effective in Reducing Hematoma and Seroma in Breast Surgery? A Systematic Review and Meta-analysis by Ammar S.A. Hashemi, MD, Sara M. Hussein, MD, Zainab H. Alshehab, Abdullah A. Al Qurashi, MD, Lucas Kreutz-Rodrigues, MD, Basel A. Sharaf, MD, DDS, FACS

“…Postoperative fluid-related complications, such as hematoma and seroma formation, are common concerns in breast surgery, adversely affecting surgical outcomes and patient recovery. …”
Get full text

Nursing of a patient with radiotherapy- and chemotherapy-induced adverse reactions treated with aruricualr acupoint pressing combined with meridian acupoint Tuina (耳穴贴压联合经穴推拿治疗放化疗后... by JIN Yi (金艺), MIN Tingyan (闵婷燕)

“…After 1 week of outpatient chemo-radiotherapy, the patient developed various adverse effects including common problems including bone marrow suppression, nausea and loss of appetite. …”
Get full text

Comparative Analysis of Natural Fibre Reinforced Composite Material Using ANSYS by K. G. Saravanan, R. Prabu, A. Sivapragasam, Nahom Daniel

“…Green composites or more commonly known as bio-composites are made up of natural fibres. …”
Get full text

Open Archives initiative: A fast way of integration into global open science by Yurii Tkachov

“…Practical Implications: Practical recommendations are provided for administrators and managers of open journals, conferences, and repositories to avoid common mistakes and effectively use OAI-PMH to ensure data interoperability and accessibility. …”
Get full text

Pimavanserin Treatment for Parkinson’s Disease Psychosis in Clinical Practice by Khashayar Dashtipour, Fiona Gupta, Robert A. Hauser, Cherian A. Karunapuzha, John C. Morgan

“…Parkinson’s disease psychosis (PDP) is a common, nonmotor symptom of Parkinson’s disease (PD), which may affect up to 60% of patients and is associated with impaired quality of life, increased healthcare costs, and nursing home placement, among other adverse outcomes. …”
Get full text

High Prevalence of Low Back Pain in College Rifle Athletes by Bailey Urbach, Cody Mansfield, Mica Harr, Matthew S. Briggs, James Onate, Laura Boucher

“…Anecdotal reports of low back pain (LBP) are common among collegiate rifle athletes, but the prevalence of LBP in this population has not yet been established in the literature…”
Get full text