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27961
In vitro and in vivo investigations of selected varieties of Areca catechu L - Phytochemical analysis, antiulcer, and wound healing activity
Published 2025-05-01“…Background: This study investigated the phytochemical composition and potential medicinal properties of arecanut grown in various regions of Karnataka. Arecanut, commonly chewed in the Indian subcontinent and Southeast Asia for its purported medicinal benefits, contains arecoline, a pyridine alkaloid known for its pharmacological effects. …”
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27962
CARDIAC-STAR: prevalence of cardiovascular comorbidities in patients with HR + /HER2 − metastatic breast cancer
Published 2025-01-01“…Conclusions We found that CV comorbidities and use of medications with risk of QTc prolongation were common in patients with newly diagnosed HR + /HER2 − mBC. …”
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27963
Novel hormonal agents in men with metastatic castration resistant prostate cancer and reduced performance status: Experiences of a specialized single center
Published 2024-12-01“…Median overall survival (OS) was 9.1 months in the BSC group and 7.0 months in the NHA group, with no significant OS benefits associated with NHA treatment. AEs and severe AEs commonly occurred, but remained indifferent between treatment groups. …”
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27964
The Impact of Preoperative Opioid Use Disorder on Complications and Costs following Primary Total Hip and Knee Arthroplasty
Published 2019-01-01“…Opioid use disorder is becoming a more common comorbidity among THA and TKA patients. This is concerning as it represents a significant risk factor for postoperative complication. …”
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27965
Reliability of Chest Wall Mobility and Its Correlation with Lung Functions in Healthy Nonsmokers, Healthy Smokers, and Patients with COPD
Published 2019-01-01“…Chest wall circumference measurements are common evaluation methods in clinical settings by therapists in order to obtain chest wall mobility. …”
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27966
Yeti claws: Cheliped sexual dimorphism and symmetry in deep-sea yeti crabs (Kiwaidae).
Published 2025-01-01“…Sexual dimorphism is a common feature of decapod crustaceans, but little is known about its prevalence in species from deep-sea habitats. …”
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27967
Machine learning identification of a novel vasculogenic mimicry-related signature and FOXM1’s role in promoting vasculogenic mimicry in clear cell renal cell carcinoma
Published 2025-03-01“…Background: Clear Cell Renal Cell Carcinoma (ccRCC), the predominant subtype of renal cell carcinoma (RCC), ranks among the most common malignancies worldwide. Vasculogenic mimicry (VM) plays a pivotal role in tumor progression, being closely linked with heightened chemoresistance and adverse prognosis in cancer patients. …”
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27968
Single‐cell landscape of the intrahepatic ecosystem in alcohol‐related liver disease
Published 2025-01-01“…Abstract Alcohol‐related liver disease (ALD) is a common chronic liver disease caused by long‐term excessive alcohol consumption and responsible for more than half of all liver‐related deaths worldwide. …”
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27969
Efficacy and safety of immunotherapy for head and neck squamous cell carcinoma: a meta-analysis of randomized clinical trials
Published 2025-01-01“…BackgroundHead and neck squamous cell carcinoma (HNSCC) is one of the most common types of cancer worldwide and immune checkpoint inhibitors have shown favorable therapeutic effects in recurrent or metastatic or locally advanced head and neck squamous cell carcinoma (R/M/LA HNSCC). …”
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27970
Epidemiology & genotyping of rotavirus gastroenteritis and rotavirus associated intussusception in preschool children in central Uttar Pradesh
Published 2025-01-01“…Conclusion: The study confirms a significant burden of RV among young children admitted with AGE this region of India. G3 P8 was the most common RV strain isolated.…”
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27971
Four decades of phenology in an alpine amphibian: trends, stasis, and climatic drivers
Published 2023-01-01“…The goal of this study is to assess the main factors determining the timing of breeding in an alpine population of the common toad (Bufo bufo) and to describe the observed shifts in its breeding phenology. …”
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27972
Transcriptomic reprogramming and epigenetic regulation underlying pollination-dependent and auxin-induced fruit set in tomato
Published 2025-02-01“…Genome-wide transcriptomic profiling of the flower-to-fruit transition, either pollination-induced or triggered by auxin treatment, shows that both types of triggers modulate the expression of a common large set of genes primarily expressed in maternal tissues. …”
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27973
Burnout in healthcare – the Emperor’s New Clothes
Published 2023-09-01“…Burnout is common among physicians; it severely alters their health and has a negative impact on functioning of healthcare systems. …”
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27974
Higher detectability of amyloid with phenol Congo red compared with alkaline Congo red
Published 2024-11-01“…Early diagnosis, when the deposits are minimal, determines the prognosis and requires histological confirmation. The commonly adopted gold standard technique is alkaline Congo red (ACR) staining, though its sensitivity is limited. …”
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27975
On the risks of secure attachment in infancy: Childhood irritability and adolescent depression predicted by secure attachment and high approach behaviours at 14-months towards a ca...
Published 2023-04-01“…Analyses used path analysis using the gsem command in Stata.ResultsThere were interactions between attachment security and inter-parental violence for age 9 irritability (p = .084) and age 13 depression (p = .039) which arose from greater levels of psychopathology among secure children exposed to inter-parental violence. …”
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27976
Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs
Published 2021-01-01“…Combination therapy is a common approach for clinical treatment of type 2 diabetes mellitus, especially for patients with poor monotherapy. …”
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27977
Best practices in the management of thyroid dysfunction induced by immune checkpoint inhibitors
Published 2025-01-01“…Immune checkpoint inhibitors (ICIs) frequently cause immune-related adverse events (irAEs), with thyroid irAEs being the most common endocrine-related irAEs. The incidence of overt thyroid irAEs was in the range of 8.9–22.2% in real-world settings, typically triggered by antibodies against PD-1 and PD-L1 and rarely by anti-CTLA-4 antibodies alone. …”
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27978
Digital eye strain: prevalence and associated socio-demographic factors among banking assistants in Colombo District, Sri Lanka
Published 2025-01-01“…With the excess usage, digital eye strain is now becoming the most common occupational hazard among the digital device users. …”
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27979
Catastrophic expenditure associated with childhood hospitalisation for acute illness in Kenya and Uganda: a cross-sectional study
Published 2025-01-01“…Caregivers reported borrowing, selling property and withdrawing other children from school to cope with costs.Conclusions Despite intentions of free healthcare services for under 5, families of acutely ill children very commonly faced catastrophic expenditure, especially for children with CSM. …”
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27980
The milpa, from Mesoamerica to present days, a multicropping traditional agricultural system serving agroecology
Published 2024-11-01“…The association of maize (Zea mays ssp. mays), common bean (Phaseolus vulgaris), and squash (Cucurbita ssp.) within the milpa represents the most emblematic multi-cropping subsistence system of Mesoamerica. …”
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