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27781
Chemical Constituents of the Bark of Zanthoxylum gilletii (Rutaceae) and Their In Vitro Antiplasmodial and Molecular Docking Studies
Published 2022-01-01“…The phytochemical investigations of the methanol extract of Zanthoxylum gilletii bark led to the isolation of thirteen compounds identified as two alkaloids including one acridone 5-hydroxynoracronycine (1) and one benzo [c] phenanthridine decarine (2), three lignans trans- and cis-fagaramide (3 and 4) and sesamin (5), two coumarins scoparone (6) and scopoletin (7), three pentacyclic triterpenoids fridelin (8), lupeol (9) and erythrodiol-3-O-palmitate (10), one phenolic compound vanillic acid (11) as well as two common steroids stigmasterol (12), and its derivative stigmasterol-3-O-β-D-glucopyranoside (13). …”
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27782
Spatiotemporal variability and functional redundancy obscure effects of urbanization on strawberry pollinators
Published 2025-01-01“…We observed 61 bee species visiting strawberry flowers, most commonly Lasioglossum, Ceratina, and Augochlorella species. …”
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27783
The association between melatonin hormone and reproductive hormones in polycystic ovary syndrome: A case–control study
Published 2024-01-01“…Abstract Background: One of the common endocrine disorders is polycystic ovary syndrome (PCOS) with prevalence of about 5%–15% of women within reproductive age. …”
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27784
Organizational readiness for implementation: a qualitative assessment to explain survey responses
Published 2025-01-01“…Conclusion Study findings reinforce the importance of collaborative and community-engaged survey design and the need to address the common challenges dissemination and implementation surveys may be vulnerable to. …”
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27785
Activity of CDK4/6 inhibitors and parameters affecting survival in elderly patients in age-subgroups: Turkish Oncology Group (TOG) retrospective study
Published 2024-12-01“…Grade 3–4 AEs were reported in 42.7% for the entire group, and neutropenia was the most common (37.3%). It can be concluded that combination therapy with palbociclib or ribociclib with an ET partner has similar efficacy and is safe among subgroups of older patients diagnosed with HR+/HER2-MBC.…”
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27786
DENND5B Gene Expression as a Trigger for the Development of Diabetes Mellitus–Peripheral Artery Disease: Insights from a Univariate and Multivariate Mendelian Randomization Study
Published 2024-12-01“…The COLOC analysis provided strong evidence suggesting that DENND5B and the DM-PAD trait were influenced by the common causal variant rs1150948. Conclusion: Our study has pinpointed several crucial genes (DENND5B, C4A, and CYP21A2), notably the DENND5B gene, as potential regulators in the pathogenesis of DM-PAD. …”
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27787
Lecturers' teaching competencies towards improving teaching and learning process in universities in Tanzania: Students’ perspectives
Published 2025-01-01“…This will help lecturers to develop a common understanding of the teaching competencies and maintain teaching quality. …”
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27788
Inequalities in physical comorbidity: a longitudinal comparative cohort study of people with severe mental illness in the UK
Published 2015-12-01“…We calculated the prevalence of SMI by UK country, English region and deprivation quintile, antipsychotic and antidepressant medication prescription rates for people with SMI, and prevalence rates of common comorbidities in people with SMI compared with people without SMI.Design Retrospective cohort study from 2000 to 2012.Setting 627 general practices contributing to the Clinical Practice Research Datalink, a UK primary care database.Participants Each identified case (346 551) was matched for age, sex and general practice with 5 randomly selected control cases (1 732 755) with no diagnosis of SMI in each yearly time point.Outcome measures Prevalence rates were calculated for 16 conditions.Results SMI rates were highest in Scotland and in more deprived areas. …”
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27789
The age-adjusted international prognostic index 2 (A-FLIPI2) for elderly patients with follicular lymphoma
Published 2025-02-01“…Follicular lymphoma (FL) is a common B-cell lymphoma and typically affects the elderly population. …”
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27790
Philosophical and Cognitive Aspects of Visual Metaphor in Political Discourse
Published 2024-12-01“…Eco, R. Barth, Yu.M. Lotman. For the purpose of the present research methodology of analysis of visual metaphor with subsequent parameters were developed, which includes research methods of cognitive linguistics, semiotics and cultural studies. …”
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27791
Genetic basis of depressive disorders
Published 2019-07-01“…Depression is a common mental disorder being one of the main causes of disability and mortality worldwide. …”
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27792
An online intervention relationship enhancement couple therapy program versus systematic desensitization on sexual performance anxiety in women undergoing infertility treatment wit...
Published 2025-02-01“… Background: Sexual performance anxiety is common among infertility treatments. Psychological interventions are options for couples who do not tolerate psychiatric medications or like psychotherapy with pharmacotherapy. …”
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27793
Towards global elimination of lymphatic filariasis: a systematic review of the application of spatial epidemiological methods to enhance surveillance and support elimination progra...
Published 2024-05-01“…Thirty-one (50.8%) studies used spatial statistical modelling, with model-based geostatistics being the most common method. Spatial autocorrelation and hotspot analysis were applied in 30 studies (49.2%). …”
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27794
A literature review of recent advances in gastric cancer treatment: exploring the cross-talk between targeted therapies
Published 2025-01-01“…Abstract Background Gastric cancer (GC) ranks fourth in global mortality rates and fifth in prevalence, making it one of the most common cancers worldwide. Recent clinical studies have highlighted the potential of immunotherapies as a promising approach to treating GC. …”
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27795
Exploring genetic structures and shared sites between alcohol, cheese intake, and inflammatory bowel disease
Published 2025-01-01“…BackgroundAn association has been observed between alcohol and cheese intake and the onset of inflammatory bowel disease (IBD), necessitating further exploration from a genetic structural perspective.MethodsThe present analysis was focused on the intake of alcohol and cheese in conjunction with IBD genome-wide association study (GWAS) data, with the objective of exploring genetic correlations and identifying common loci. Initially, overall genetic correlations were assessed employing two methodologies: linkage disequilibrium score regression (LDSC) and genetic covariance analyzer (GNOVA). …”
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27796
Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3
Published 2025-01-01“…EoxPL are altered in ASCVD by a commonly used cardiovascular therapy, and LPCAT3 was identified as the acyltransferase generating aspirin-sensitive 12-LOX diacyl forms. …”
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27797
Adaptive deep feature representation learning for cross-subject EEG decoding
Published 2024-12-01“…Utilizing sufficient EEG data from other subjects to aid in modeling the target subject presents a potential solution, commonly referred to as domain adaptation. Most current domain adaptation techniques for EEG decoding primarily focus on learning shared feature representations through domain alignment strategies. …”
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27798
On the Adversarial Robustness of Decision Trees and a Symmetry Defense
Published 2025-01-01“…Second, GBDT adversarial robustness as currently defined can decrease by training with additional samples, even training samples, which counters the common wisdom that more training samples should increase robustness. …”
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27799
Diagnostic value of miR-193a-5p in severe pneumonia and its correlation with prognosis
Published 2025-01-01“…Abstract Background Severe pneumonia is a common disease in children, with rapid progression and easy complications of respiratory failure, endangering the lives of children. …”
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27800
Conservation networks do not match the ecological requirements of amphibians
Published 2023-06-01“…We highlighted a mismatch between the most suitable amphibian habitats at the regional scale and the conservation network, both for common species and for species of high conservation concern. …”
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