Exploration of the Potential Mechanisms of Wumei Pill for the Treatment of Ulcerative Colitis by Network Pharmacology by Jinke Huang, Yijun Zheng, Jinxin Ma, Jing Ma, Mengxiong Lu, Xiangxue Ma, Fengyun Wang, Xudong Tang

“…Based on the identified overlapping common targets, drug-ingredient-target gene network, Gene Ontology (GO) analysis, Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, and protein-protein interaction (PPI) analysis were conducted. …”
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Real-world experiences with brentuximab vedotion-based regimens in systemic anaplastic large cell lymphoma: a multi-center retrospective study by Zhiqiang Zhao, Qinchuan Yu, Liping Su, Jianxia He, Jie Tao, Yanfeng Xi, Yujiao Guo, Yanhong Luo, Lieyang Wang

“…Neurological toxicities were commonly observed but resolved following the completion of treatment.ConclusionBV has proven to be effective and well-tolerated in real-world settings for the treatment of sALCL, reinforcing its potential as a promising option for first-line or subsequent therapy. …”
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Sequence of episodic memory-related behavioral and brain-imaging abnormalities in type 2 diabetes by Bo Hu, Ying Yu, Xin-Wen Yu, Min-Hua Ni, Yan-Yan Cui, Xin-Yu Cao, Ai-Li Yang, Yu-Xin Jin, Sheng-Ru Liang, Si-Ning Li, Pan Dai, Ke Wu, Lin-Feng Yan, Bin Gao, Guang-Bin Cui

“…Abstract Background Episodic memory decline is a common complication of type 2 diabetes (T2D). To comprehensively explore the neural mechanisms underlying it, we aimed to explore the sequence that episodic memory-related behavioral and brain-imaging biomarkers appear abnormal in the progression of T2D. …”
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Linking the Historical Sample of the Netherlands with the USA Censuses, 1850–1940 by Diogo Paiva, Francisco Anguita, Kees Mandemakers

“…The Historical Sample of the Netherlands (HSN) contains about 85,500 persons born in the Netherlands between 1812 and 1922. …”
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Examining the Impact of MOCK OSCE on Test Anxiety and clinical Performance of First-Term Nursing Students in the OSCE Exam by Masoumeh Fuladvandi, Shirin Ghazi, Masoumeh Abdi, Shahin Salarvand

“…Background: The Objective Structured Clinical Examination (OSCE) is a commonly used method for assessing clinical skills among nursing students. …”
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Management of Canine Leishmaniasis and the Treatment Trends of Veterinarians in Aegean Region of Türkiye: A Questionnaire-based Survey by Metin Pekağırbaş, Mehmet Karakuş, Elif Dönmez, Hüseyin Gökhan Özdemir, Yusuf Özbel, Seray Töz

“…Results: Most of the clinicians (n=99; 96.1%) reported that localized alopecia was one of the most common clinical findings in the suspicion of CanL, while only four clinician did not consider this finding in the suspicion of CanL. …”
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A Real-World Comparison Between Adjuvant Docetaxel with Cyclophosphamide (TC) and Anthracycline–Taxane Chemotherapy in Early HER-2 Negative Breast Cancer by Danilo Giffoni de Mello Morais Mata, Rossanna C. Pezo, Kelvin K. W. Chan, Ines Menjak, Andrea Eisen, Maureen Trudeau

“…Conclusion: Our study shows that anthracycline–taxane regimens were the most commonly prescribed adjuvant chemotherapy options in HER2-negative BC. …”
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Combination of Composite Autonomic Symptom Score 31 and Heart Rate Variability for Diagnosis of Cardiovascular Autonomic Neuropathy in People with Type 2 Diabetes by Zhiyin Zhang, Yujin Ma, Liujun Fu, Liping Li, Jie Liu, Huifang Peng, Hongwei Jiang

“…Cardiovascular autonomic neuropathy (CAN) is a common but severe problem of diabetes, which a timely diagnosis may have important clinical implications. …”
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Preliminary Studies on the Development and Evaluation of Instant Pounded Yam from <i>Dioscorea alata</i> by Abiodun A Adeola, Bolanle O Otegbayo, Sola Ogunnoiki

“…Of all the species of Dioscorea, D. alata possesses higher multiplication ratio and better storability, and requires less capital and labour to produce than the most common specie, D. rotundata. Exploitation of the industrial potential of D. alata by diversifying its utilisation through the development of novel products will expand its utilisation. …”
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Autonomous security analysis and penetration testing model based on attack graph and deep Q-learning network by Cheng FAN, Guoqing HU, Taojie DING, Zhanhua ZHANG

“…With the continuous development and widespread application of network technology, network security issues have become increasingly prominent.Penetration testing has emerged as an important method for assessing and enhancing network security.However, traditional manual penetration testing methods suffer from inefficiency,human error, and tester skills, leading to high uncertainty and poor evaluation results.To address these challenges, an autonomous security analysis and penetration testing framework called ASAPT was proposed, based on attack graphs and deep Q-learning networks (DQN).The ASAPT framework was consisted of two main components:training data construction and model training.In the training data construction phase, attack graphs were utilized to model the threats in the target network by representing vulnerabilities and possible attacker attack paths as nodes and edges.By integrating the common vulnerability scoring system (CVSS) vulnerability database, a “state-action”transition matrix was constructed, which depicted the attacker’s behavior and transition probabilities in different states.This matrix comprehensively captured the attacker’s capabilities and network security status.To reduce computational complexity, a depth-first search (DFS) algorithm was innovatively applied to simplify the transition matrix, identifying and preserving all attack paths that lead to the final goal for subsequent model training.In the model training phase, a deep reinforcement learning algorithm based on DQN was employed to determine the optimal attack path during penetration testing.The algorithm interacted continuously with the environment, updating the Q-value function to progressively optimize the selection of attack paths.Simulation results demonstrate that ASAPT achieves an accuracy of 84% in identifying the optimal path and exhibits fast convergence speed.Compared to traditional Q-learning, ASAPT demonstrates superior adaptability in dealing with large-scale network environments, which could provide guidance for practical penetration testing.…”
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Russian University Cities: Expectations vs. Reality by I. D. Turgel, K. D. Bugrov, A. D. Oykher

“…The article concludes that, due to the specifics of its genesis and evolution, the phenomenon of a university city in Russia receives a new significance, reflecting the diversity of relationships between a large city and a complex, hierarchical system of universities operating in the socio-economic space of a common territory.…”
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Blue Light Therapy: A Skin Treatment Mask using Blue Light to cure Skin Disorders by Aleena Kamal, Minahil Kamal, Bushra Mehboob, Tayaba Naz, Shoaib Zafar, Syed Muddusir Hussain

“… Skin acne and disease are the most common medical conditions that lead from mild to moderate if not treated in time. …”
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The Associations Between Temperament and Self-Oriented, Other-Oriented, and Dual-Harmful Behaviors in Emerging Adults by Serafine Dierickx, Dirk Smits, Glenn Kiekens, Laurence Claes

“…Self- and other-oriented harmful behaviors are common among emerging adults. Individuals who engage in both forms of behavior, termed dual-harm, experience more adverse outcomes in comparison to individuals who engage in either. …”
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Enhancing oral cancer treatment via photodynamic therapy: Gold nanoparticle-based delivery system for 5-aminolevulinic acid (5-ALA) by Romesa Soomro, Mohamed Abdelmonem, Bachren Azra Saputra, Che Azurahanim Che Abdullah

“…Oral squamous cell carcinoma (OSCC) is a significant global health concern, responsible for approximately 300,000 new cases and 145,000 deaths annually, making it the sixth most common malignancy worldwide. Traditional treatments, including surgery, radiation, and chemotherapy, often lead to severe side effects such as physical disfigurement, functional loss, and systemic toxicity. …”
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A sector fast encryption algorithm for color images based on one-dimensional composite sinusoidal chaos map. by Ye Tao, Wenhua Cui, Shanshan Wang, Yayun Wang

“…The algorithm can also resist some common attacks and accidents, such as exhaustion attack, differential attack, noise attack, information loss and so on.…”
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The focal mechanism and field investigations of mining-induced earthquake by super-thick and weak cementation overburden strata fracturing by Xianxi Bai, Anye Cao, Changbin Wang, Yaoqi Liu, Chengchun Xue, Xu Yang, Yao Yang, Songwei Wang, Qi Hao

“…In Ordos mining area, super-thick and weak cementation overburden strata (STWCS) are common occurrence in Jurassic coal seam overlying strata. …”
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The Use of Iliac Stem Prosthesis for Acetabular Defects following Resections for Periacetabular Tumors by Massimiliano De Paolis, Alessio Biazzo, Carlo Romagnoli, Nikolin Alì, Sandro Giannini, Davide Maria Donati

“…Between 1999 and 2012, 45 patients underwent pelvic resections for periacetabular bone tumors followed by reconstruction with stem cup prosthesis. The most common diagnosis was CS (chondrosarcoma, 29 cases), followed by OS (osteosarcoma, 9 cases) and metastasis (3 cases). …”
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Increase in assisted suicide in Switzerland: did the socioeconomic predictors change? Results from the Swiss National Cohort by Marcel Zwahlen, Nicole Steck, Christoph Junker

“…Crude rates of assisted suicide more than tripled during the study period from 3.60 to 11.21 per 100 000 person-years; the increase was more pronounced in the older age group. Cancer was the most common underlying diagnosis (41.8%), but the percentage dying assisted was highest among patients with diseases of the nervous system (5.25% in the younger and 1.23% in the older age group). …”
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Otsu’s Image Segmentation Algorithm with Memory-Based Fruit Fly Optimization Algorithm by Ruishuai Chai

“…In this paper, the most common pepper noise in grayscale image noise is investigated in depth in the median filtering algorithm, and the improved median filtering algorithm, adaptive switching median filtering algorithm, and adaptive polar median filtering algorithm are applied to the OTSU algorithm. …”
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GENERAL EQUATION OF THE HYDRAULIC FRICTION LAW FOR HINDERED FALLING OF AN INDIVIDUAL BALL AND FLUID MOTION IN GRANULAR LAYERS by M. V. Krautsov, A. M. Krautsov

“…The authors generalize the results of theoretical and experimental studies, employ the theory of similarity, and establish that the laws of hydraulic friction for the mentioned hydromechanical processes share the common ground described by one general equation that provides basis for obtaining the individual formulae computing the studied hydromechanical processes. …”
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