<i>Ex Vivo</i> Regional Gene Therapy Compared to Recombinant BMP-2 for the Treatment of Critical-Size Bone Defects: An In Vivo Single-Cell RNA-Sequencing Study by Arijita Sarkar, Matthew C. Gallo, Jennifer A. Bell, Cory K. Mayfield, Jacob R. Ball, Mina Ayad, Elizabeth Lechtholz-Zey, Stephanie W. Chang, Osamu Sugiyama, Denis Evseenko, Jay R. Lieberman

“…Additionally, gene therapy was associated with an anti-inflammatory microenvironment; macrophages expressing canonical anti-inflammatory markers were more common in the gene therapy group. In contrast, pro-inflammatory markers were more highly expressed in the rhBMP-2 group. …”
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Achieving Medication‐Free Remission in Patients With Juvenile Dermatomyositis by Ilaria Maccora, Hermine I. Brunner, Amy Cassedy, Mekibib Altaye, Megan Quinlan‐Waters, Daniel J. Lovell, Alexei Grom, Sheila T. Angeles‐Han

“…Results Of 55 patients with JDM (63.6% female, age median [interquartile range (IQR)] 6 [3.5–12] years), 29 (52.7%) achieved MFR after a median (IQR) of 33 (22.5–55.2) months. MFR was more common in those who were younger at JDM diagnosis (median 5 vs 8 years, P = 0.008), had early resolution of disease activity (median 11 vs 18 months, P < 0.001), and presented with Gottron papules (χ2 = 5.25; P = 0.022) and elevated lactate dehydrogenase (χ2 = 4.82, P = 0.028). …”
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Severe Acute Respiratory Syndrome Coronavirus 2 Infection Symptoms in Pregnancy and Maternal and Neonatal Complications Due to COVID-19: A Systematic Review by Sepideh Miraj, Azadeh Asgarian, Abolfazl Mohammadbeigi, Maryam Derakhshani

“…Neonatal ICU admission, newborn death, neonatal sepsis, low birth weight and respiratory distress syndrome, tachypnoea, asphyxia and pneumothorax were the most common outcomes of COVID-19 infection in offspring of pregnant subjects. …”
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Aging Alters Olfactory Bulb Network Oscillations and Connectivity: Relevance for Aging-Related Neurodegeneration Studies by A. Ahnaou, D. Rodriguez-Manrique, S. Embrechts, R. Biermans, N. V. Manyakov, S. A. Youssef, W. H. I. M. Drinkenburg

“…The olfactory bulb (OB) and the hippocampus, both regions of the brain considered critical for the processing of odors and spatial memory, are commonly affected by aging. Using an aged wild-type C57B/6 mouse model, we sought to define the effects of aging on hippocampal plasticity and the integrity of cortical circuits. …”
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Therapeutic Effect of Traditional Chinese Medicine on a Rat Model of Branch Retinal Vein Occlusion by Pan Long, Weiming Yan, Jianwen Liu, Manhong Li, Tao Chen, Zuoming Zhang, Jing An

“…Branch retinal vein occlusion (BRVO) is a common retinal vascular disorder leading to visual impairment. …”
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Delayed-release prednisone improves fatigue and health-related quality of life: findings from the CAPRA-2 double-blind randomised study in rheumatoid arthritis by Frank Buttgereit, Rieke Alten, Amy Grahn, Robert J Holt, Patricia Rice

“…Objectives Like morning stiffness, fatigue is a common, debilitating symptom of rheumatoid arthritis (RA). …”
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Genomic data suggest parallel dental vestigialization within the xenarthran radiation by Emerling, Christopher A, Gibb, Gillian C, Tilak, Marie-Ka, Hughes, Jonathan J, Kuch, Melanie, Duggan, Ana T, Poinar, Hendrik N, Nachman, Michael W, Delsuc, Frédéric

“…First, we found strong evidence of complete enamel loss in the common ancestor of sloths and anteaters, suggested by the inactivation of five enamel-associated genes (AMELX, AMTN, MMP20, ENAM, ACP4). …”
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Synovial sarcoma. Evaluation of Prognosis with Emphasis on the Study of DNA Ploidy and Proliferation (PCNA and Ki-67) Markers by José M. Lopes, Einar Hannisdal, Bodil Bjerkehagen, Øyvind S. Bruland, Håvard E. Danielsen, Erik O. Pettersend, Manuel Sobrinho-Simões, Jahn M. Nesland

“…Controversy still exists regarding the validity of parameters commonly used in the evaluation of prognosis of patients with synovial sarcoma (SS). …”
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Do Upper and Lower Camptocormias Affect Gait and Postural Control in Patients with Parkinson’s Disease? An Observational Cross-Sectional Study by Christian Geroin, Marialuisa Gandolfi, Isacco Maddalena, Nicola Smania, Michele Tinazzi

“…Gait impairments and camptocormia (CC) are common and debilitating in patients with Parkinson’s disease (PD). …”
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Investigating the Relationship between Socioeconomic Status and Traffic Behaviors of Pedestrians in Marand by Sepideh Harzand-Jadidi, Abolfazl Rahimi Bonab, Morteza Haghighi, Mohammad Saadati, Saeid Mousavi

“…Also, unsafe behaviors were more common among female pedestrians and young age groups. …”
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Creative Cuisine in The Mountains: Yörük Food Culture by Akdag Gürkan, Soylu Aykut Göktuğ

“…Cooking dried meat and eating natural herbs collected from the highlands are common. In the Yörük food culture, grains such as bulgur and wheat are used to prepare staple dishes such as flatbreads and tortillas. …”
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Static Standing Trunk Sway Assessment in Amputees – Effects of Sub-Threshold Stimulation by L. Ming-Yih, S. Kok-Soon, L. Chih-Feng

“…The single leg quiet standing test is measure considered to assess postural steadiness in a static position by a spatial measurement. The common notion is that a better postural steadiness, i.e. less postural sway, allows for longer time single leg quiet standing. …”
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Exploring Force Production Reliability across Different Levels of Clinical Experience during a Simulated One-handed Instrument-Assisted Soft Tissue Mobilization Treatment: A Pilot... by Moni Syeda, Jason Bartholomew, Shayane Valenzuela Santiago, Ashley J Reeves, Nickolai JP Martonick, Scott W Cheatham, Russell T Baker Jr.

“…# Background Instrument-assisted soft tissue mobilization (IASTM) is a commonly utilized intervention for musculoskeletal pain and dysfunction. …”
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Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome by Yu Wang, Yicong Wang, Yuning Chen, Wenhan Lu, Xiaoyu Tong, Jiajia Li, Wenhao Gao, Rui Huang, Wei Hu, Yi Feng

“…Both EA and MA share a common therapeutic target in the integrin family. …”
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Intraocular Foreign Bodies: Clinical Characteristics and Factors Affecting Visual Outcome by Yanyan Liang, Shuang Liang, Xiaoli Liu, Danyan Liu, Jialiang Duan

“…The demographic data, cause of injury, characteristics of IOFBs, postinjury ocular manifestations, and surgical details of the subjects were collected, and the factors affecting visual outcome and endophthalmitis development were analyzed. Results. The most common cause of IOFBs was the propulsion of foreign bodies into the eye due to hammering (149 cases, 61.57%), followed by foreign body penetration (57 cases, 23.55%). …”
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Changes in Vertical Stratification of Neotropical Nymphalid Butterflies at Forest Edges Are Not Directly Caused by Light and Temperature Conditions by Brian K. Oye, Ryan I. Hill

“…We found strong evidence of an edge effect in these butterflies and confirmed strong differences in light and temperature, showing that the edge understory differs little from forest canopy conditions. Of 41 species common to both forests and edges, 28 shifted to have a lower canopy probability at the edge, and our model detected a decrease in canopy probability of 0.165. …”
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Pharmacovigilance imbalance analysis of VEGFR-TKI-related taste and smell disorders by Zhong-hua Fu, Chenglong Zhao, Yaqin Wang, Lei Zhang, Lei Wang

“…Dysgeusia, taste disorder, and ageusia were the most commonly reported preferred terms (PTs) in VEGFR-TKI-related TSDs, accounting for more than 90% of the reported cases. …”
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The frequency of distribution of the genotypes of the IL4 polymorphism (rs 2243250) in psoriasis and psoriatic arthritis by A. A. Barilo, M. V. Smolnikova, S. V. Smirnova

“…The study of genetic polymorphism of PS and PsA will allow identification of common diagnostic criteria for the progression of pathology. …”
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SpikeDroidDB: AN INFORMATION SYSTEM FOR ANNOTATION OF MORPHOMETRIC CHARACTERISTICS OF WHEAT SPIKE by M. A. Genaev, E. G. Komyshev, Fu Hao, V. S. Koval, N. P. Goncharov, D. A. Afonnikov

“…We used SpikeDroidDB for the digitization and annotation of a collection of ears of F2 hybrids from crosses between the Australian cultivar of common wheat Triple Dirk and accession KU506 of Chinese wheat Triticum yunnanense. …”
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Immunohistochemical Expression of FOXP3+ Regulatory T Cells in Proteinuric Primary Glomerulopathies by Georgios Vlachopanos, Argyrios Georgalis, Pinelopi Korkolopoulou, Efstratios Patsouris, Harikleia Gakiopoulou

“…FOXP3+ Tregs intrarenal infiltration in primary glomerulopathies is common. FOXP3+ Tregs’ increased expression may be associated with milder histological lesions. …”
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