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1861
A novel mRNA-based multi-epitope vaccine for rabies virus computationally designed via reverse vaccinology and immunoinformatics
Published 2025-08-01“…The cytotoxic T lymphocytes (CTLs), helper T lymphocytes (HTLs), and linear B-cell epitopes (LBLs) were mapped and prioritized from four top-ranking vaccine targets (nucleoprotein, phosphoprotein, matrix, and glycoprotein) that were highly antigenic, nonallergenic, nontoxic, and nonhuman homologs. The selected epitopes exhibited strong binding affinity to high-frequency HLA alleles, as evidenced by highly negative ΔG values and low dissociation constants, predicting efficient T-cell recognition and broad population coverage (96.01% globally). …”
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1862
Development of a fluorophilic ion-exchange material with dual binding mechanism for solid-phase extraction of PFAS
Published 2025-11-01“…The findings underscore the potential of this innovative polyelectrolyte as a selective, regenerable, and efficient alternative to conventional SPE materials, qualifying it as a superior candidate for PFAS analysis.…”
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1863
MATHEMATICAL MODELS OF DECISION SUPPORT IN THE PROBLEMS OF LOGISTICS NETWORKS OPTIMIZATION
Published 2021-12-01“…The practical use of the proposed models and procedures will reduce the time and capacity complexity of decision support technologies, and through the use of the proposed selection procedures - to improve their quality across a variety of functional and cost indicators.…”
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1864
AIpollen: An Analytic Website for Pollen Identification Through Convolutional Neural Networks
Published 2024-11-01“…With the rapid development of artificial intelligence, deep learning has been widely applied to complex tasks such as computer vision and natural language processing, demonstrating its outstanding performance. …”
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1865
Introducing a Novel Figure of Merit for Evaluating Stability of Perovskite Solar Cells: Utilizing Long Short-Term Memory Neural Networks
Published 2025-01-01“…Our findings indicate that the LSTM model effectively captures and predicts the complex relationships between key design parameters—efficiency, fill factor, and open-circuit voltage—and degradation-induced changes in PSCs. …”
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1866
The Impact of Natural Resources on the Development of Countries
Published 2017-09-01“…In the present study, qualitative comparative analysis method has been used as a means of quantitative and qualitative research and a powerful tool to analyze the causal complexities. Therefore, four phases of data fuzzy, formation of values table, a method to analyze the variables using complex causality and validation of the results of the research were considered. …”
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1867
Methods of Digital Bite Registration: A Narrative Review
Published 2025-05-01“…However, in patients with complex conditions such as edentulous patients or patients with improper bites, the use of digital scanners can pose challenges. …”
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1868
Impacts of clinical research units on clinical research — a systematic review of empirical studies
Published 2025-04-01“…While previous studies suggest that clinical research units (CRUs) provide critical support and expertise for complex clinical research, their necessity for ensuring high-quality clinical research remains uncertain. …”
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1869
Infrastructure support for software import substitution
Published 2018-06-01“…The purpose of the research is to improve the efficiency of software import substitution processes. …”
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1870
Insights into the effects of biomass feedstock and pyrolysis conditions on the energy storage capacity and durability of standard biochar-based phase-change composites
Published 2025-01-01“…Abstract Material selection and production conditions are imperative for determining the functional performances of composite materials. …”
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1871
Spatial Characteristics and Influencing Factors of Human Settlement Environment in the Kuye River Basin
Published 2025-06-01“…From living by water and grass of early human beings to today’s “Four Determinations Based on Water”, the complex relationship between people and water is an important clue for the formation and development of human civilization, and the harmonious relationship between people and water in river basins is an important basis for achieving sustainable development. …”
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1872
Towards the Integration of Additive Manufacturing for Freeform Steel and Glass Façade Construction
Published 2024-04-01“…For the structural node, three different nodes are designed per the design guidelines of selected metal AM methods. The three node prototypes are manufactured, and compared in terms of their fabrication efficiency and material efficiency. …”
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1873
In Silico Design of Dual Estrogen Receptor and Hsp90 Inhibitors for ER-Positive Breast Cancer Through a Mixed Ligand/Structure-Based Approach
Published 2024-12-01“…Traditional endocrine therapies, including aromatase inhibitors, selective estrogen receptor degraders/antagonists (SERDs), and selective estrogen receptor modulators (SERMs), have improved outcomes for metastatic ER+ breast cancer. …”
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1874
Fluorescent EGTA-derived carbon dots for turn on–off–on detection of Fe3+ and ascorbic acid via hydrothermal synthesis and cellular imaging
Published 2025-07-01“…This approach demonstrates excellent selectivity for AA over dopamine and other amino acids, providing a reliable method for distinguishing AA in complex biological matrices. …”
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1875
Tailored nano clay blends for enhanced dye mixture adsorption in wastewater treatment
Published 2024-12-01“…The maximum dye removal efficiency was attained using HAMT (1:1) blend for effluent with an equimolar concentration of selected dyes. …”
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1876
Seasonal fluctuations in individual milk parameters in free-range cows
Published 2025-04-01“…Their minimum and maximum limits were determined at Komyshuvatskyi Milk Complex LLC, which is key when determining the grade of milk. …”
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1877
Process and Performance of Desulfurizing Thenardite Resource Utilization Based on Electrodialysis with Modified Ion Exchange Membranes
Published 2025-08-01“…Notably, after six testing cycles, the modified membranes exhibited excellent stability in ion selectivity and migration efficiency, meeting the requirements for long-term industrial operation. …”
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1878
SWIPT-Enabled Cooperative Wireless IoT Networks With Friendly Jammer and Eavesdropper: Outage and Intercept Probability Analysis
Published 2023-01-01“…In this context, a low-complexity, sub-optimal, but efficient relay selection method is proposed. …”
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1879
Phosphorus-solubilizing fungi promote the growth of Fritillaria taipaiensis P. Y. Li by regulating physiological and biochemical reactions and protecting enzyme system–related gene...
Published 2025-01-01“…Phosphorus-solubilizing fungi can promote the dissolution of insoluble phosphate complex, which benefits plant nutrition. Another strategy for efficiently cultivating traditional Chinese medicine plants is to combine the soil with phosphorus-solubilizing fungi to provide nutrients and other desired features. …”
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1880
Key technologies for exploration and geological evaluation of deep carbon storage spaces
Published 2025-05-01“…Methods such as the analytic hierarchy process (AHP), GIS, and machine learning are combined to optimize site selection decisions. To address the complexity of deep carbon storage spaces, integrated seismic and electrical exploration technologies significantly improve reservoir identification accuracy: full-waveform inversion (FWI) characterizes pore-fracture structures, gravity-magnetic inversion constructs deep structural models, and multiphysical data fusion reduces the non-uniqueness of inversion results. …”
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