Characterization of a blaKPC-3-carrying plasmid in a clinical isolate of Klebsiella pneumoniae belonging to the emerging successful clone ST147 by Esther Recacha, Mercedes Delgado-Valverde, Marina R. Pulido, Elena Pérez-Nadales, Patricia Pérez-Palacios, Inés Portillo-Calderón, Juan Manuel Sánchez-Calvo, Irene Gracia-Ahufinger, Álvaro Pascual

“…ABSTRACT Klebsiella pneumoniae ST147 has emerged as a successful clone able to efficiently disseminate a number of carbapenemases, including blaKPC. …”
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Isolation and identification of a matrine-producing fungal strain from petroleum-contaminated soil by Mao Dongxia, Guo Dandan, Wu Lingling, Tian Xiaoxue, Zhang Shengxiang, Liu Tao, Ma Xiaokui

“…In addition, the production efficiency is not high enough, and the product has many impurities. …”
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Identification of tRF-29-79MP9P9NH525 as a biomarker and tumor suppressor of gastric cancer via regulating KIF14/AKT pathway by Jiaxin Ge, Ji Dai, Haoqiang Ji, Jie Guo, Xiaoban Shen, Desen Sun, Qiang Chen, Pan Chen, Guoliang Ye, Junming Guo, Shuangshuang Zhang

“…It was found that tissue tRF-29 showed effective diagnostic efficiency in GC and could discriminate different gastric mucosa. …”
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Identification of Metabolites of Ferulic Acid in Human after Oral Administration by Qian PAN, Wei LI, Yang YANG, Yong-qiang ZHAO, Li LIAN, Qing-qing CONG, Li-hong WANG, Yue-lin SONG, Qian HONG

“…Liquid chromatography coupled with mass spectrometry (LC-MS) combines the high-efficiency separation capabilities of LC with the powerful qualitative analysis advantage of MS, playing a vital and irreplaceable role in the in-depth study of chemical profiles in complex systems. …”
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Metallurgical Waste for Sustainable Agriculture: Converter Slag and Blast-Furnace Sludge Increase Oat Yield in Acidic Soils by Olga V. Zakharova, Peter A. Baranchikov, Svetlana P. Chebotaryova, Gregory V. Grigoriev, Nataliya S. Strekalova, Tatiana A. Grodetskaya, Igor N. Burmistrov, Sergey V. Volokhov, Denis V. Kuznetsov, Alexander A. Gusev

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Global biogeography of N₂-fixing microbes: <i>nifH</i> amplicon database and analytics workflow by M. Morando, J. D. Magasin, S. Cheung, S. Cheung, M. M. Mills, J. P. Zehr, K. A. Turk-Kubo

“…Multiple datasets are efficiently and consistently processed with a specialized DADA2 pipeline to identify amplicon sequence variants (ASVs). …”
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Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice by Yan Gong, Yuzhuo Zhang, Xingda Chen, Zelin Zhou, Weicheng Qin, Yanchi Gan, Jiahui He, Jizhi Ma, Guifeng Chen, Qi Shang, Kai Tang, Honglin Chen, Yu Liu, De Liang, De Liang, Gengyang Shen, Xiaobing Jiang, Zhaojun Cheng, Zhaojun Cheng, Zhaojun Cheng

“…BackgroundThe origin of intervertebral disc degeneration (IDD) is highly complex, where both cartilage endplate remodeling and vertebral osteoporosis are of utmost importance. …”
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Integrative review of artificial intelligence applications in nursing: education, clinical practice, workload management, and professional perceptions by Rabie Adel El Arab, Omayma Abdulaziz Al Moosa, Mette Sagbakken, Ahmed Ghannam, Fuad H. Abuadas, Joel Somerville, Joel Somerville, Abbas Al Mutair, Abbas Al Mutair, Abbas Al Mutair, Abbas Al Mutair, Abbas Al Mutair

“…Learners also reported an increased cognitive load and heightened stress levels when navigating these more complex, AI-driven activities.Clinical decision support and monitoringAI-enabled alert algorithms and wearable sensors enabled nurses to detect subtle signs of patient deterioration and fever significantly earlier than conventional methods, supporting timelier clinical interventions. …”
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Development and retrospective validation of an artificial intelligence system for diagnostic assessment of prostate biopsies: study protocol by Martin Eklund, Brett Delahunt, Lars Egevad, Hemamali Samaratunga, Mattias Rantalainen, Marcello Gambacorta, Einar Gudlaugsson, Bodil Ginnerup Pedersen, Xiaoyi Ji, Karina Dalsgaard Sørensen, Kelvin Szolnoky, Nita Mulliqi, Anders Blilie, Henrik Olsson, Matteo Titus, Geraldine Martinez Gonzalez, Sol Erika Boman, Masi Valkonen, Svein Reidar Kjosavik, José Asenjo, Paolo Libretti, Marcin Braun, Radzislaw Kordek, Roman Łowicki, Kristina Hotakainen, Päivi Väre, Benedicte Parm Ulhøi, Pekka Ruusuvuori, Toyonori Tsuzuki, Emilius Adrianus Maria Janssen, Kimmo Kartasalo

“…Many pathology departments are also facing an increasingly unsustainable workload due to rising prostate cancer incidence and a decreasing pathologist workforce coinciding with increasing requirements for more complex assessments and reporting. Digital pathology and artificial intelligence (AI) algorithms for analysing whole slide images show promise in improving the accuracy and efficiency of histopathological assessments. …”
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Timescales of Polycyclic Aromatic Hydrocarbon and Dust Continuum Emission from Gas Clouds Compared to Molecular Gas Cloud Lifetimes in PHANGS-JWST Galaxies by Jaeyeon Kim, Mélanie Chevance, Lise Ramambason, Kathryn Kreckel, Ralf S. Klessen, Daniel A. Dale, Adam K. Leroy, Karin Sandstrom, Ryan Chown, Thomas G. Williams, Sumit K. Sarbadhicary, Francesco Belfiore, Frank Bigiel, Enrico Congiu, Oleg V. Egorov, Eric Emsellem, Simon C. O. Glover, Kathryn Grasha, Annie Hughes, J. M. Diederik Kruijssen, Janice C. Lee, Debosmita Pathak, Ismael Pessa, Erik Rosolowsky, Jiayi Sun, Jessica Sutter, David A. Thilker

“…After star formation is detected in H α , mid-IR emission persists for 3–7 Myr during the stellar feedback phase, covering 70%–80% of the H α emission. …”
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Research advances on reisistance to kiwifruit bacterial canker by ZHANG Min, SUN Leiming, FU Rong, LIN Miaomiao, WANG Ran, QI Xiujuan

“…Since the first KBC was detected in Japan in 1984, it has been discovered in various countries around the world. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…While HCPs recognised complexities of the DPC, data also support the feasibility of delivery by non-allergy specialists with appropriate resources, training, facilities, local policies and governance framework and escalation or referral pathways to allergy specialists. …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…In line with Medical Research Council guidance for complex interventions, we also conducted an integrated multimethod multiperspective (from patients, suitable informants and NHS professionals) process evaluation. …”
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Hierarchical diagnostic approach for performance problems in cloud computing platforms by MI Hai-bo1, WANG Huai-min1, CAI Hua2, YIN Gang1, ZHOU Qi2, SUN Ting-tao2, ZHOU Yang-fan3

“…A hierarchical diagnosis approach,namely Magnifier,was proposed,which models the execution path graph of a user request as component layer,module layer and function layer,and detects anomalies from higher layer to lower layer separately.Extensive experiments were conducted on the Alibaba cloud computing platform.The results indicate that,under the conditions of large volume of data and high complexity of execution paths,Magnifier can accurately and efficiently locate the prime causes of performance degradation.…”
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Utilizing process mining in quality management: A case study in radiation oncology. by Mohammad Bakhtiari

“…Radiation oncology is known for its complexity, inherent risks, and sheer volume of data. …”
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Load identification method based on one class classification combined with fuzzy broad learning by Wang Yi, Wang Xiaoyang, Li Songnong, Chen Tao, Hou Xingzhe, Fu Xiuyuan

“…Considering the recognition rate and model complexity, the fuzzy broad learning system is used to classify and recognize the screened samples. …”
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Sparse Cumulants Fitting for Direction-of-Arrival Estimation without Redundancy by Shuang Li, Xiaoxiao Jiang, Sai Ma, Yingguan Wang

“…Simulation results are presented to illustrate the effectiveness and efficiency of the proposed method.…”
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Multi-Objective Optimization of Manufacturing Process Using Artificial Neural Networks by Katarína Marcineková, Andrea Janáková Sujová

“…This multi-objective optimizing solution facilitates enhanced process efficiency. By integrating Systems Theory, Complexity Theory, and adaptive management, this research advances sustainable process improvements by minimizing resource use, reducing waste, and enhancing overall system efficiency.…”
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Intronomics-MIP: a snakemake pipeline for analyzing multilocus intron polymorphisms in species identification and population genomics by A. Scapolatiello, E. Boscari, L. Schiavon, N. Vitulo, L. Congiu

“…These MIPs serve as powerful multiple-allelic markers, primarily useful for distinguishing species, identifying cryptic species, disentangling species complexes and detecting hybridization, but can also be informative for assessing population structure without prior species knowledge. …”
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Background reference frame generation method for surveillance video based on image block codebook model by Wei ZHANG, Yu WANG, Xinyi CHEN, Yanwen WANG, Qingyang JING, Weimin LEI

“…To solve the problems that the background reference frames are seriously contaminated by the foreground, and the bit rate increases suddenly incurred by the one-time transmission of the background frames, a progressive background frame generation method with image block as the basic unit was proposed for surveillance video application.An image block codebook model based on clustering was formulated.The image blocks at the same position in the video sequence were effectively clustered by using perceptual hash-based element matching.The background symbol was accurately detected by using the characteristics of the background image area.A complete background frame was produced by extracting the background blocks in different frames based on the codebook model.Experimental results demonstrate that the proposed method achieves 17.89% coding efficiency for luma component compared with standard HM16.20, and can effectively improve the quality of the produced background reference frame.Besides, the proposed method complexity meets the real-time requirements of video applications.…”
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