Identification of the microglia-associated signature in experimental autoimmune encephalomyelitis by Yan Wu, Jianhong Wang, Jianhong Wang, Bo Chen, Yuxue Guo, Yuxue Guo, Ping Gan, Yanbing Han

“…A machine learning approach incorporating five distinct algorithms was applied to select a robust multigene signature. …”
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Evaluation of internal reference genes for photodynamic inactivation-based quantitative PCR studies in Staphylococcus aureus by Kamila Koči, Jozefína Theissová, Katarína Bilská, Juraj Koči

“…Raw qPCR data of six candidate reference genes (femA, glyA, hu, rho, rpoD, rrsC) were analyzed with four standard algorithms, geNorm and NormFinder included in a GenEx software package, as well as with BestKeeper and ΔCq to determine the stability of the genes. …”
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The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy by Jifeng Feng, Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Qixun Chen

“…It is yet unknown how SOS levels relate to the prognosis of esophageal squamous cell carcinoma (ESCC). The current research aims to explore the prognostic role of systemic oxidative stress index (SOSI) on ESCC receiving neoadjuvant immunochemotherapy (nICT).MethodsRetrospective recruitment was used to identify 224 nICT-treated ESCC patients. …”
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First M87 Event Horizon Telescope Results. VI. The Shadow and Mass of the Central Black Hole by The Event Horizon Telescope Collaboration, Kazunori Akiyama, Antxon Alberdi, Walter Alef, Keiichi Asada, Rebecca Azulay, Anne-Kathrin Baczko, David Ball, Mislav Baloković, John Barrett, Dan Bintley, Lindy Blackburn, Wilfred Boland, Katherine L. Bouman, Geoffrey C. Bower, Michael Bremer, Christiaan D. Brinkerink, Roger Brissenden, Silke Britzen, Avery E. Broderick, Dominique Broguiere, Thomas Bronzwaer, Do-Young Byun, John E. Carlstrom, Andrew Chael, Chi-kwan Chan, Shami Chatterjee, Koushik Chatterjee, Ming-Tang Chen, Yongjun Chen, Ilje Cho, Pierre Christian, John E. Conway, James M. Cordes, Geoffrey B. Crew, Yuzhu Cui, Jordy Davelaar, Mariafelicia De Laurentis, Roger Deane, Jessica Dempsey, Gregory Desvignes, Jason Dexter, Sheperd S. Doeleman, Ralph P. Eatough, Heino Falcke, Vincent L. Fish, Ed Fomalont, Raquel Fraga-Encinas, Per Friberg, Christian M. Fromm, José L. Gómez, Peter Galison, Charles F. Gammie, Roberto García, Olivier Gentaz, Boris Georgiev, Ciriaco Goddi, Roman Gold, Minfeng Gu, Mark Gurwell, Kazuhiro Hada, Michael H. Hecht, Ronald Hesper, Luis C. Ho, Paul Ho, Mareki Honma, Chih-Wei L. Huang, Lei Huang, David H. Hughes, Shiro Ikeda, Makoto Inoue, Sara Issaoun, David J. James, Buell T. Jannuzi, Michael Janssen, Britton Jeter, Wu Jiang, Michael D. Johnson, Svetlana Jorstad, Taehyun Jung, Mansour Karami, Ramesh Karuppusamy, Tomohisa Kawashima, Garrett K. Keating, Mark Kettenis, Jae-Young Kim, Junhan Kim, Jongsoo Kim, Motoki Kino, Jun Yi Koay, Patrick M. Koch, Shoko Koyama, Michael Kramer, Carsten Kramer, Thomas P. Krichbaum, Cheng-Yu Kuo, Tod R. Lauer, Sang-Sung Lee, Yan-Rong Li, Zhiyuan Li, Michael Lindqvist, Kuo Liu, Elisabetta Liuzzo, Wen-Ping Lo, Andrei P. Lobanov, Laurent Loinard, Colin Lonsdale, Ru-Sen Lu, Nicholas R. MacDonald, Jirong Mao, Sera Markoff, Daniel P. Marrone, Alan P. Marscher, Iván Martí-Vidal, Satoki Matsushita, Lynn D. Matthews, Lia Medeiros, Karl M. Menten, Yosuke Mizuno, Izumi Mizuno, James M. Moran, Kotaro Moriyama, Monika Moscibrodzka, Cornelia Müller, Hiroshi Nagai, Neil M. Nagar, Masanori Nakamura, Ramesh Narayan, Gopal Narayanan, Iniyan Natarajan, Roberto Neri, Chunchong Ni, Aristeidis Noutsos, Hiroki Okino, Héctor Olivares, Tomoaki Oyama, Feryal Özel, Daniel C. M. Palumbo, Nimesh Patel, Ue-Li Pen, Dominic W. Pesce, Vincent Piétu, Richard Plambeck, Aleksandar PopStefanija, Oliver Porth, Ben Prather, Jorge A. Preciado-López, Dimitrios Psaltis, Hung-Yi Pu, Venkatessh Ramakrishnan, Ramprasad Rao, Mark G. Rawlings, Alexander W. Raymond, Luciano Rezzolla, Bart Ripperda, Freek Roelofs, Alan Rogers, Eduardo Ros, Mel Rose, Arash Roshanineshat, Helge Rottmann, Alan L. Roy, Chet Ruszczyk, Benjamin R. Ryan, Kazi L. J. Rygl, Salvador Sánchez, David Sánchez-Arguelles, Mahito Sasada, Tuomas Savolainen, F. Peter Schloerb, Karl-Friedrich Schuster, Lijing Shao, Zhiqiang Shen, Des Small, Bong Won Sohn, Jason SooHoo, Fumie Tazaki, Paul Tiede, Remo P. J. Tilanus, Michael Titus, Kenji Toma, Pablo Torne, Tyler Trent, Sascha Trippe, Shuichiro Tsuda, Ilse van Bemmel, Huib Jan van Langevelde, Daniel R. van Rossum, Jan Wagner, John Wardle, Jonathan Weintroub, Norbert Wex, Robert Wharton, Maciek Wielgus, George N. Wong, Qingwen Wu, André Young, Ken Young, Ziri Younsi, Feng Yuan, Ye-Fei Yuan, J. Anton Zensus, Guangyao Zhao, Shan-Shan Zhao, Ziyan Zhu, Joseph R. Farah, Zheng Meyer-Zhao, Daniel Michalik, Andrew Nadolski, Hiroaki Nishioka, Nicolas Pradel, Rurik A. Primiani, Kamal Souccar, Laura Vertatschitsch, Paul Yamaguchi

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Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study by Yejing Zhao, Yejing Zhao, Xiang Wang, Jie Zhang, Yanyan Zhao, Yi Li, Ji Shen, Ying Yuan, Jing Li

“…The contemporary consensus firmly emphasizes the urgent need to reorient research efforts toward the early detection of preclinical Alzheimer’s disease (AD) or mild cognitive impairment (MCI). …”
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Preoxygenation in difficult airway management: high-flow oxygenation by nasal cannula versus face mask (the PREOPTIDAM study). Protocol for a single-centre randomised study by Samir Jaber, Karim Asehnoune, Fanny Feuillet, Mickael Vourc’h, Donatien Huard, Gabrielle Baud, Arthur Guichoux, Marielle Surbled, Melanie Tissot, Anne Chiffoleau, Christophe Guitton

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A review of altimetry waveform retracking for inland water levels by Xinyuan Deng, Linghong Ke, Liguang Jiang, Karina Nielsen, Xiaomei Fan, Jida Wang, Chunqiao Song

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A Comparison of Recent Global Time-Series Land Cover Products by Peilin Li, Yan Wang, Chisheng Wang, Lin Tian, Meijiao Lin, Siyao Xu, Chuanhua Zhu

“…This study addresses the critical gap in cross-product comparability by systematically comparing five recent global time-series land cover products (GLC_FCS30D, Esri Land Cover, MCD12Q1, ESA CCI, and Dynamic World) against a reference dataset (CGLS-LC100). …”
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Electrophysiological changes in the acute phase after deep brain stimulation surgery by Lucia K. Feldmann, Diogo Coutinho Soriano, Jeroen Habets, Valentina D'Onofrio, Jonathan Kaplan, Varvara Mathiopoulou, Katharina Faust, Gerd-Helge Schneider, Doreen Gruber, Georg Ebersbach, Hayriye Cagnan, Andrea A. Kühn

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Prevalence of Rocahepevirus ratti (rat hepatitis E virus) in humans and rats in China by Xiuji Cui, Jianwen Situ, Ting Tang, Zhiyu Li, Dongzhui Chen, Stanley Siu-Fung Ho, Hiu-Laam Chung, Tsz-Chung Wong, Yonghao Liang, Chaowen Deng, Yongxian Su, Huijun Cai, Simon Kam-Fai Lo, Shiyao Huang, Sheng Zeng, Liyuan Zhang, Yunchun Chen, Shusheng Wu, Estie Hon-Kiu Shun, Nicholas Foo-Siong Chew, James Yiu-Hung Tsoi, Kelvin Hon-Yin Lo, Fanfan Xing, Vincent Chi-Chung Cheng, Kwok-Yung Yuen, Feifei Yin, Jasper Fuk-Woo Chan, Siddharth Sridhar

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Evaluation of the shielding initiative in Wales (EVITE Immunity): protocol for a quasiexperimental study by Stephen Jolles, Ashley Akbari, Andrew Carson-Stevens, Helen Snooks, Alan Watkins, Adrian Edwards, Ann John, Alison Porter, Victoria Williams, Bridie Angela Evans, Ronan Lyons, Bernadette Sewell, Mark Rhys Kingston, Tony Whiffen, Jane Lyons, Rowena Bailey, Catherine A Thornton, Lesley Bethell, Samantha Bufton, Lucy Dixon

“…Clinically extremely vulnerable people identified through algorithms and screening of routine National Health Service (NHS) data were individually and strongly advised to stay at home and strictly self-isolate even from others in their household. …”
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Prehospital critical care beyond advanced life support for out-of-hospital cardiac arrest: A systematic review by Adam J. Boulton, Rachel Edwards, Andrew Gadie, Daniel Clayton, Caroline Leech, Michael A. Smyth, Terry Brown, Joyce Yeung

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Older people and stroke: a machine learning approach to personalize the rehabilitation of gait by Elvira Maranesi, Federico Barbarossa, Leonardo Biscetti, Marco Benadduci, Elisa Casoni, Ilaria Barboni, Fabrizia Lattanzio, Lorenzo Fantechi, Daniela Fornarelli, Enrico Paci, Sara Mecozzi, Manuela Sallei, Mirko Giannoni, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Valentina Di Donna, Roberta Bevilacqua

“…Machine learning (ML) algorithms—Random Forest (RF), Support Vector Machine (SVM), and k-Nearest Neighbors (KNN)—were employed for classification, with RF demonstrating superior performance in accuracy, precision, recall (all exceeding 85%), and F1 score compared to SVM and KNN. …”
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Improving Sleep Disorder Diagnosis Through Optimized Machine Learning Approaches by Md. Atiqur Rahman, Israt Jahan, Maheen Islam, Taskeed Jabid, Md Sawkat Ali, Mohammad Rifat Ahmmad Rashid, Mohammad Manzurul Islam, Md. Hasanul Ferdaus, Md Mostofa Kamal Rasel, Mahmuda Rawnak Jahan, Shayla Sharmin, Tanzina Afroz Rimi, Atia Sanjida Talukder, Md. Mafiul Hasan Matin, M. Ameer Ali

“…This fact highlights the need for accurate machine learning algorithms (MLAs) for analyzing, monitoring, and diagnosing sleep disorders. …”
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Machine Learning-Driven Transcriptome Analysis of Keratoconus for Predictive Biomarker Identification by Shao-Hsuan Chang, Lung-Kun Yeh, Kuo-Hsuan Hung, Yen-Jung Chiu, Chia-Hsun Hsieh, Chung-Pei Ma

“…Our findings provide a novel research platform for the evaluation of keratoconus using machine learning-based approaches, offering valuable insights into its pathogenesis and potential therapeutic targets.…”
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Evaluation of a content-based image retrieval system for radiologists in high-resolution CT of interstitial lung diseases by Benjamin Böttcher, Marly van Assen, Roberto Fari, Philipp L. von Knebel Doeberitz, Eun Young Kim, Eugene A. Berkowitz, Felix G. Meinel, Carlo N. De Cecco

“…Accuracy was assessed on the CT pattern level, comparing readers’ diagnoses with reference diagnoses and CBIR results with region-of-interest (ROI) patterns. …”
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Influencing factors of cross screening rate and its intelligent prediction model by Lala ZHAO, Feng XU, Chenlong DUAN, Chenhao GUO, Wei WANG, Haishen JIANG, Jinpeng QIAO

“…The research results provide a reference for the establishment of the machine learning intelligent prediction model of the screening rate of the cross screen. …”
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Retrotransposon methylation profiles and survival in Black women with high-grade serous ovarian carcinoma by Christelle Colin-Leitzinger, Katherine A. Lawson-Michod, Courtney E. Johnson, Irma M. Vlasac, Sean Yoder, Tania Mesa, Dana Roeber, Chad Huff, Michelle A. T. Hildebrandt, Kristin Haller, Anthony J. Alberg, Elisa V. Bandera, Melissa Bondy, Michele L. Cote, Theresa Hastert, Edward S. Peters, Paul D. Terry, Andrew B. Lawson, Andrew Berchuck, Brooke L. Fridley, Jing-Yi Chern, Jennifer A. Doherty, Jeffrey R. Marks, Joellen M. Schildkraut, Brock C. Christensen, Lucas A. Salas, Lauren C. Peres

“…Methods Methylation levels of LTR, LINE-1, and Alu (type of SINE) in 200 HGSOC tumors were predicted using a random forest approach and clustered using multiple consensus algorithms. Associations between RE methylation clusters and survival were evaluated using Cox proportional hazard regression, adjusting for age, stage, and debulking status. …”
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Estimation and evaluation of iron reserves in the eastern area of Eileh1 mine, Razavi Khorasan province by Hamid Esmati Daroneh, Maryam Gholamzadeh

“…Introduction The evaluation of mineral reserves is conducted using various methods, which differ in calculation algorithms, accuracy, speed, the state of the mineral, and the characteristics of exploration activities (Madani, 1997; Ahmadi, 2010). …”
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In-Silico discovery of novel cephalosporin antibiotic conformers via ligand-based pharmacophore modelling and de novo molecular design by Rayhan Chowdhury, Samia Akter Saima, Md. Al Amin, Md. Kawsar Habib, Ramisa Binti Mohiuddin, Ali Mohamod Wasaf Hasan, Roksana Khanam, Shahin Mahmud

“…These candidates were then fused with the cephalosporin core using genetic algorithms and fragment-based design, resulting in 30 novel synthetic models. …”
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