A metaproteomic analysis of the piglet fecal microbiome across the weaning transition by Israel Rivera, KaLynn Harlow, KaLynn Harlow, Robert N. Cole, Robert O’Meally, Wesley Garrett, Weili Xiong, William Oliver, James E. Wells, Katie Lynn Summers, Nisan Chhetri, Olga Postnikova, Lea Rempel, Matt Crouse, Bryan Neville, Cary Pirone Davies

Get full text

Uso de la videocolonoscopia para el tamizaje del cáncer colorrectal: estudio descriptivo by F.E. Jabif, P.N. Cherne, C. Pintos, J.A. Pollán, A. Murujosa

“…The prevalence of CRC diagnosis was 0.6% and the most common findings were polyps (36.7%) and diverticula (35.5%). …”
Get full text

Pan‐Cancer Survival Impact of Immune Checkpoint Inhibitors in a National Healthcare System by Sean R. Miller, Matthew Schipper, Lars G. Fritsche, Ralph Jiang, Garth Strohbehn, Erkin Ötleş, Benjamin H. McMahon, Silvia Crivelli, Rafael Zamora‐Resendiz, Nithya Ramnath, Shinjae Yoo, Xin Dai, Kamya Sankar, Donna M. Edwards, Steven G. Allen, Michael D. Green, Alex K. Bryant

Get full text

Genomic, transcriptomic, and immunogenomic landscape of over 1300 sarcomas of diverse histology subtypes by Alex Soupir, Oscar E. Ospina, Oliver Hampton, Michelle Churchman, Michael Radmacher, Dale Hedges, David McKean, Phaedra Agius, Saman Zeeshan, Nathan D. Seligson, Raphael Pollock, David Liebner, James L. Chen, Gabriel Tinoco, Bodour Salhia, Martin McCarter, Breelyn A. Wilky, Benjamin J. Miller, Michael J. Cavnar, John S. Groundland, Bryan P. Schneider, Gregory Riedlinger, Stephen B. Edge, Christopher A. Moskaluk, Kenneth Cardona, Abdul Rafeh Naqash, Ricardo J. Gonzalez, John E. Mullinax, David M. Joyce, Odion Binitie, G. Douglas Letson, Arash O. Naghavi, Mihaela Druta, Damon R. Reed, Erin M. Siegel, Jamie K. Teer, Brooke L. Fridley, Andrew S. Brohl

Get full text

Effects of neoadjuvant immunotherapy on hearing in patients with head and neck squamous cell carcinoma by Bryce Hambach, Anhelina Bilokon, John Lee, L. Noelle Allemang, Jennifer Chisholm, Chris K. Zalewski, Julie Christensen, Carmen C. Brewer, James L. Gulley, Clint T. Allen, Lisa L. Cunningham, Katharine A. Fernandez

Get full text

Medicinal plants: bioactive compounds, biological activities, combating multidrug-resistant microorganisms, and human health benefits - a comprehensive review by Mohamed T. El-Saadony, Ahmed M. Saad, Dina Mostafa Mohammed, Sameh A. Korma, Mohammad Y. Alshahrani, Ahmed Ezzat Ahmed, Essam H. Ibrahim, Essam H. Ibrahim, Heba M. Salem, Heba M. Salem, Samar Sami Alkafaas, Abdullah M. Saif, Sara Samy Elkafas, Sara Samy Elkafas, Mohamed A. Fahmy, Taia A. Abd El-Mageed, Mariam M. Abady, Mariam M. Abady, Hanya Y. Assal, Marawan K. El-Tarabily, Betty T. Mathew, Synan F. AbuQamar, Khaled A. El-Tarabily, Salam A. Ibrahim

Get full text

Patient-derived tumor explant models of tumor immune microenvironment reveal distinct and reproducible immunotherapy responses by Rita Turpin, Karita Peltonen, Jenna H. Rannikko, Ruixian Liu, Anita N. Kumari, Daniel Nicorici, Moon Hee Lee, Minna Mutka, Panu E. Kovanen, Laura Niinikoski, Tuomo Meretoja, Johanna Mattson, Petrus Järvinen, Kanerva Lahdensuo, Riikka Järvinen, Sara Tornberg, Tuomas Mirtti, Pia Boström, Ilkka Koskivuo, Anil Thotakura, Jeroen Pouwels, Maija Hollmén, Satu Mustjoki, Juha Klefström

Get full text

Discovery of a novel class NSD2 inhibitor for multiple myeloma with t(4;14)+ by Sae Matsuoka, Naoki Osada, Hirokazu Kubota, Ko Kikuzato, Hiroo Koyama, Takeshi Sonoda, Akiko Idei, Minoru Yoshida, Masaki Kikuchi, Takashi Umehara, Chiduru Watanabe, Teruki Honma, Hiroshi Yasui, Sho Ikeda, Naoto Takahashi, Hideki Nakasone, Jiro Kikuchi, Yusuke Furukawa

Get full text

Cuproptosis: a novel therapeutic mechanism in lung cancer by Cheng Luo, Xinhui Wu, Shipeng Zhang, Junwen Tan, Yuzhi Huo, Xinyue Zhang, Bo Ning, Yuanhang Ye, Fei Wang

“…Abstract Background Lung cancer, one of the most prevalent and deadly malignant tumors, is increasingly common globally in terms of both morbidity and mortality rates. …”
Get full text

Small fiber damage in patients with chemo-induced polyneuropathy by O. A. Tikhonova, D. S. Druzhinin, O. P. Tuchina, A. V. Vinogradova, S. A. Doktorova, M. I. Dolgaleva, A. M. Tynterova

“…Statistical processing was performed using the GraphPad Prism 8.0.1 program package. Quantitative variables were evaluated using the Kolmogorov–Smirnov test. …”
Get full text

Impact of yoga on the central and peripheral vascular function among desk-based workers: A single-centered trial study [version 4; peer review: 1 approved, 2 approved with reservat... by Suresh Sukumar, Guruprasad V, Rajagopal Kadavigere, Banumathe K R, Poovitha Shruthi P, Koustubh Kamath, Peter Hogg, Shovan Saha, Leena R David, Sneha Ravichandran, Shivashankar K N, Vaishali K

Get full text

Translational randomized phase II trial of cabozantinib in combination with nivolumab in advanced, recurrent, or metastatic endometrial cancer by John Wright, Stephanie Lheureux, Ilaria Colombo, Ramy Gadalla, Pamela S Ohashi, Xuan Li, Lisa Wang, Matthew S Block, David G Brooks, Andrea Jewell, Carolyn McCourt, Eugenia Girda, Sarah Temkin, Gini F Fleming, Linda Duska, Daniela E Matei, Panagiotis A Konstantinopoulos, Ben X Wang, Stephanie L Gaillard, Michael McHale, Floor J Backes, Theresa L Werner, Siobhan Kehoe, Rachel Wildman, Shirin Soleimani, Scott Lien, Trevor Pugh

Get full text

Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity by Pereira AP, Janela D, Areias AC, Molinos M, Tong X, Bento V, Yanamadala V, Cohen SP, Correia FD, Costa F

“…Satisfaction was very high (> 9/10) in all BMI groups.Conclusion: Despite worse baseline clinical presentations, obesity groups achieved high completion rates, engagement, and significant clinical improvements comparable to the non-obesity group, highlighting the potential of a digital program for this population.Plain Language Summary: Obesity is a common risk factor for musculoskeletal conditions. …”
Get full text

The Black and African American Connections to Parkinson’s Disease (BLAAC PD) study protocol by Lana M. Chahine, Naomi Louie, J Solle, Fulya Akçimen, Andrew Ameri, Samantha Augenbraun, Sabrina Avripas, Sarah Breaux, Christopher Causey, Shivika Chandra, Marissa Dean, Elizabeth A. Disbrow, Lauren Fanty, Jessica Fernandez, Erin R. Foster, Erin Furr Stimming, Deborah Hall, Vanessa Hinson, Ashani Johnson-Turbes, Cabell Jonas, Camilla Kilbane, Scott A. Norris, Bao-Tran Nguyen, Mahesh Padmanaban, Kimberly Paquette, Carly Parry, Natalia Pessoa Rocha, Ashley Rawls, Ejaz A. Shamim, Lisa M. Shulman, Rebeka Sipma, Julia Staisch, Rami Traurig, Rainer von Coelln, Peter Wild Crea, Tao Xie, Zih-Hua Fang, Alyssa O’Grady, Catherine M. Kopil, Maggie McGuire Kuhl, Andrew Singleton, Cornelis Blauwendraat, Sara Bandres-Ciga, the BLAAC PD Study and the Global Parkinson’s Genetics Program (GP2)

“…The genetics of PD spans the etiological risk spectrum, from rare, highly deleterious variants linked to monogenic forms with Mendelian patterns of inheritance, to common variation involved in sporadic disease. A major limitation in PD genomics research is lack of racial and ethnic diversity. …”
Get full text

Association Between Visceral Fat and Lung Function Impairment in Overweight and Grade I Obese Women: A Cross-Sectional Study by Anamei Silva-Reis, Boris Brill, Maysa Alves Rodrigues Brandao-Rangel, Renilson Moraes-Ferreira, Dobroslav Melamed, Helida Cristina Aquino-Santos, Claudio Ricardo Frison, Regiane Albertini, Rodrigo Álvaro Brandao Lopes-Martins, Luís Vicente Franco de Oliveira, Gustavo Paixao-Santos, Carlos Rocha Oliveira, Asghar Abbasi, Rodolfo P. Vieira

Get full text

Discovery and validation of frameshift-derived neopeptides in Lynch syndrome: paving the way for novel cancer prevention strategies by Marta Pineda, Sabela Carballal, María Pellisé, Liseth Rivero, Francesc Balaguer, Fátima Marín, Leticia Moreira, Teresa Ocaña, Manel Juan, Daniel Benitez-Ribas, Georgina Flórez-Grau, Joaquín Castillo-Iturra, Cristina Bayó, Giancarlo Castellano, Hardeep Kumari, Maria Daca-Alvarez, Oswaldo Ortiz, Rebeca Moreira, Julia Canet-Hermida, Capella Gabriel

Get full text

AI-powered literature search: some observations and concerns by Farooq Azam Rathore, Fareeha Farooq

“… • Institutions should provide comprehensive training to researchers and faculty members, as part of faculty development programs, emphasizing the importance of critical evaluation and ethical uses of AI-generated outputs…”
Get full text

Upstream therapy of reperfusion disorders of hemodynamics, rhythm and conduction in patients with acute myocardial infarction with diabetes mellitus and metabolic syndrome (second... by M.I. Shved, I.O. Yastremska, R.M. Ovsiychuk, L.P. Martyniuk, O.A. Prokopovych, Ya.M. Kitsak

“…STEMI on the background of T2DM and MS is significantly more common in middle-aged men. The development of STEMI was associated with the presence of comorbid conditions: hypertension, T2DM and MS, chronic kidney disease, and combined risk factors for coronary heart disease. …”
Get full text

Investigating the effect of polygenic background on epilepsy phenotype in ‘monogenic’ familiesResearch in context by Karen L. Oliver, Ingrid E. Scheffer, Colin A. Ellis, Bronwyn E. Grinton, Samuel F. Berkovic, Melanie Bahlo, Zaid Afawi, Dina Amrom, Eva Andermann, Jocelyn F. Bautista, Susannah T. Bellows, Judith Bluvstein, Gregory D. Cascino, Seo-Kyung Chung, Patrick Cossette, Sarah W. Curtis, Norman Delanty, Orrin Devinsky, Dennis Dlugos, Michael P. Epstein, Catharine Freyer, Micheline Gravel, Rebekah V. Harris, Erin L. Heinzen, Olivia J. Henry, Heidi E. Kirsch, Robert C. Knowlton, Eric H. Kossoff, Rebecca Loeb, Daniel H. Lowenstein, Anthony G. Marson, Heather C. Mefford, Paul V. Motika, Terence J. O'Brien, Ruth Ottman, Juliann M. Paolicchi, Slave Petrovski, William O. Pickrell, Mark I. Rees, Lynette G. Sadleir, Jerry J. Shih, Rani K. Singh, Michael C. Smith, Philip E.M. Smith, Rhys H. Thomas, Judith Weisenberg, Peter Widdess-Walsh, Melodie R. Winawer

Get full text

Peripheral MicroRNA Signatures in Adolescent Depression by Alice Morgunova, Nicholas O’Toole, Fatme Abboud, Saché Coury, Gary Gang Chen, Maxime Teixeira, Eamon Fitzgerald, Gustavo Turecki, Anthony J. Gifuni, Ian H. Gotlib, Corina Nagy, Michael J. Meaney, Tiffany C. Ho, Cecilia Flores

Get full text