Caregiving burdens of task time and task difficulty among paid and unpaid caregivers of persons living with dementia by Matthew Lee Smith, Matthew Lee Smith, Jodi L. Southerland, Malinee Neelamegam, Gang Han, Gang Han, Shinduk Lee, Shinduk Lee, Chung Lin Kew, Juanita-Dawne R. Bacsu, Elyse Couch, Steffi M. Kim, Monique J. Brown, Ayse Malatyali, Lucas Wilson, Zahra Rahemi, Jeremy Holloway, Marcia G. Ory, Marcia G. Ory

“…Findings highlight the importance of caregiver support services and programming for mental health.…”
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COMORBIDITIES OF ISCHEMIC HEART DISEASE WITH OTHER NON-COMMUNICABLE DISEASES IN ADULT POPULATION: AGE AND RISK FACTORS ASSOCIATION by S. A. Shalnova, R. G. Oganov, A. D. Deev, A. E. Imaeva, М. М. Lukyanov, G. V. Artamonova, Т. М. Gatagonova, Yu. I. Grinshtein, D. V. Duplyakov, А. Yu. Efanov, Yu. V. Zhernakova, V. A. Ilyin, R. A. Libis, A. V. Minakov, V. A. Nevzorova, S. V. Nedogoda, S. A. Romanchuk, O. P. Rotar, I. A. Trubacheva, E. V. Shlyakhto, S. A. Boytsov, Yu. A. Balanova, G. A. Muromtseva, S. E. Evstifeeva, A. V. Kapustina, M. N. Mamedov, S. K. Gutnova, Z. A. Toguzova, G. V. Tolparov, N. V. Kulakova, N. V. Shestakova, M. V. Mokshina, L. V. Rodionova, E. V. Chumachek, A. A. Ledyaeva, R. A. Kasimov, A. A. Shabunova, G. V. Leonidova, K. N. Kalashnikov, O. N. Kalachikova, A. I. Rossoshansky, N. A. Kondakova, A. V. Popov, K. A. Ustinova, G. I. Furmenko, N. I. Babenko, O. G. Azarin, L. V. Bondartsov, A. E. Khvostikova, O. A. Nazarova, O. A. Belova, E. A. Shutemova, M. M. Petrova, L. K. Danilova, A. A. Evsyukov, N. V. Topolskaya, V. V. Shabalin, A. I. Aristov, R. R. Ruf, A. A. Kosinova, E. N. Shmatova, D. S. Kaskaeva, I. R. Basyrova, V. Yu. Kondratenko, E. A. Lopina, D. V. Safonova, S. A. Gudkova, N. A. Cherepanova, R. S. Karpov, V. S. Kaveshnikov, V. N. Serebryakova, I. V. Medvedeva, V. P. Shava, S. V. Shalaev, O. L. Barbarash, A. E. Skripchenko, E. V. Indukaeva, T. A. Mulerova, S. A. Maksimov, N. V. Cherkass, M. V. Tabakaev, Ya. V. Danilchenko

“…Comorbidities of IHD with AH, DM and LD in adult population are common, are associated with the general FR, are increasing with the age. …”
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HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysisResearch in context by Brian C. Zhang, Tilman Schneider-Hohendorf, Rebecca Elyanow, Beatrice Pignolet, Simon Falk, Christian Wünsch, Marie Deffner, Erik Yusko, Damon May, Daniel Mattox, Eva Dawin, Lisa Ann Gerdes, Florence Bucciarelli, Lisa Revie, Gisela Antony, Sven Jarius, Christiane Seidel, Makbule Senel, Stefan Bittner, Felix Luessi, Joachim Havla, Matthias Knop, Manuel A. Friese, Susanne Rothacher, Anke Salmen, Fumie Hayashi, Roland Henry, Stacy Caillier, Adam Santaniello, Maria Seipelt, Christoph Heesen, Sandra Nischwitz, Antonios Bayas, Hayrettin Tumani, Florian Then Bergh, Gerd Meyer zu Hörste, Tania Kümpfel, Catharina C. Gross, Brigitte Wildemann, Martin Kerschensteiner, Ralf Gold, Sven G. Meuth, Frauke Zipp, Bruce A.C. Cree, Jorge Oksenberg, Michael R. Wilson, Stephen L. Hauser, Scott S. Zamvil, Luisa Klotz, Roland Liblau, Harlan Robins, Joseph J. Sabatino, Jr., Heinz Wiendl, Nicholas Schwab, Jessa Alexander, Riley Bove, Sergio Baranzini, Bruce A.C. Cree, Eduardo Caverzasi, Richard Cuneo, Stacy J. Caillier, Tiffany Cooper, Ari J. Green, Chu-Yueh Guo, Jeffrey M. Gelfand, Refujia Gomez, Sasha Gupta, Jill Hollenbach, Meagan Harms, Roland G. Henry, Stephen L. Hauser, Myra Mendoza, Jorge R. Oksenberg, Nico Papinutto, Sam Pleasure, Adam Santaniello, Joseph J. Sabatino, Jr., William A. Stern, Michael R. Wilson, Scott Zamvil, Orhan Aktas, Antje Giede-Jeppe, Barbara Gisevius, Markus Kowarik, Friedemann Paul, Veit Rothhammer, Corinna Trebst, Uwe Zettl

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Cemiplimab and diabetic ketoacidosis: a case report of a rare endocrinopathy associated with immune checkpoint inhibitors by Anna Arecco, Cristian Petolicchio, Alessandro Pastorino, Enrica Teresa Tanda, Enrica Teresa Tanda, Lara Vera, Mara Boschetti, Mara Boschetti, Francesco Cocchiara, Davide Carlo Maggi, Davide Carlo Maggi, Diego Ferone, Diego Ferone, Federico Gatto, Federico Gatto

“…ICIs are antibodies blocking several immune checkpoint pathways, as cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) with its ligand PD-L1. …”
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Proteogenomic characterization of invasive breast tumors in young women by Praveen-Kumar Raj-Kumar, Jianfang Liu, Anthony R. Soltis, Nicholas W. Bateman, Qingrong Chen, Lori A. Sturtz, Brenda Deyarmin, Mariaelena Pierobon, Tamara A. Abulez, Anupama Praveen-Kumar, Xijun Zhang, Trinh Nguyen, Chunhua Yan, Ying Hu, Kate Guion, Jeffrey A. Hooke, Albert J. Kovatich, Leigh Fantacone-Campbell, Brad Mostoller, Leonid Kvecher, Stella Somiari, Patricia S. Steeg, Padma Sheila Rajagopal, Kathleen M. Darcy, Jerry S. H. Lee, Clifton L. Dalgard, Thomas P. Conrads, Emanuel F. Petricoin, Daoud Meerzaman, Matthew D. Wilkerson, APOLLO Research Network, Xiaoying Lin, Craig D. Shriver, Stanley Lipkowitz, Hai Hu

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HPV DNA screening and vaccination strategies in Tunisia by Anas Lahdhiri, Beya Benzina, Emna Ennaifer, Haifa Tounsi, Ahlem Gzara, Soumaya Rammeh-Rommani, Oumaima Laraj, Heger Arfaoui, Robyn Stuart, Amira Kebir, Slimane BenMiled

“…Abstract In Tunisia, cervical cancer ranks as the 14th most common cancer, largely driven by high-risk of Human Papillomavirus (HPV) types, notably HPV 16 and 18. …”
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Durvalumab and tremelimumab with or without stereotactic body radiation therapy in relapsed small cell lung cancer: a randomized phase II study by Chao Zhang, Shuhua Wang, Suresh Ramalingam, Sagar Lonial, Walter Curran, Edmund K Waller, Bassel Nazha, Taofeek K Owonikoko, Conor Steuer, Suchita Pakkala, Kristin Higgins, Zhengjia Chen, Gabriel Sica, Guojing Zhang, Mohammad S Hossain, Tyler Beardslee, Fadlo R Khuri

“…Background Immune checkpoint blockade (ICB) targeting programmed cell death protein 1 and cytotoxic T lymphocyte-associated protein 4 has achieved modest clinical activity as salvage therapy in relapsed small cell lung cancer (SCLC). …”
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Claudin-9 (CLDN9) promotes gastric cancer progression by enhancing the glycolysis pathway and facilitating PD-L1 lactylation to suppress CD8+ T cell anti-tumor immunity by Xingbin Hu, Wenhao Ouyang, Haizhu Chen, Zhihong Liu, Zijia Lai, Herui Yao

“…Background: Gastric cancer (GC) is a common malignancy characterized by the absence of reliable prognostic indicators and effective therapeutic targets. …”
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Survival and transfer of Escherichia coli to fresh produce from organically managed soils amended with poultry litter by Petrina McKenzie-Reynolds, Petrina McKenzie-Reynolds, Patricia Millner, Fawzy Hashem, Lurline Marsh, Brett Smith, Annette Kenney, Arthur Allen, Salina Parveen, Amy S. Collick

“…IntroductionPoultry litter (PL) compost and heat-treated PL-pellets (PP) are common organic fertilizer/soil amendments in specialty crop production and soil health management. …”
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Take charge during treatment: a protocol for a pilot study to evaluate the impact of exercise on cardiovascular biomarkers among black and white breast cancer patients undergoing t... by Natalia Do Couto, Mary Hidde, Georgios Grigoriadis, Rodney Sparapani, Matt Durand, Michael Widlansky, Courtney Jankowski, Madeline Berendt, Bethany Canales, Sarah Golus, Laura E. Norwood Toro, Purushottam Laud, Amanda Kong, Kent Hoskins, David Lewandowski, Shane A. Phillips, David D. Gutterman, Alison J. Kriegel, Kirsten M. M. Beyer, Andreas M. Beyer, Melinda Stolley

“…Abstract Cardiotoxicity is a significant challenge associated with common first-line breast cancer (BC) anti-neoplastic (CTx) treatments including anthracyclines (AC) and targeted immunotherapies, such as anti-Her-2 therapy. …”
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Clinical features and antibiotic resistance in pediatric pneumococcal meningitis in Southern Vietnam, 2012–2023: A multicenter retrospective study by Hieu Cong Truong, Thanh Van Phan, Hung Thanh Nguyen, Thang Vinh Ho, Dai Thi Trang Vo, Thuong Vu Nguyen, Trung Vu Nguyen, Niko Speybroeck

“…These findings emphasize the urgent need for PCV introduction in the national immunization program and ongoing resistance surveillance.…”
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Knowledge about metabolic dysfunction-associated steatotic liver disease among the medical professionals from countries in the MENA region by Saleh A. Alqahtani, Yusuf Yilmaz, Mohamed El-Kassas, Khalid Alswat, Mohamed Mawardi, Faisal M. Sanai, Faisal Abaakhail, Saad Alghamdi, Waleed K. Al-Hamoudi, Fatema Nader, Maria Stepanova, Zobair M. Younossi

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Interferon gamma inhibits CXCL8–CXCR2 axis mediated tumor-associated macrophages tumor trafficking and enhances anti-PD1 efficacy in pancreatic cancer by Mingjie Zhang, Lifeng Huang, Guoping Ding, Huilian Huang, Guoliang Cao, Xu Sun, Neng Lou, Qiang Wei, Tao Shen, Xiaodong Xu, Liping Cao, Qiang Yan

“…Background Pancreatic cancer (PC) is a common malignancy of the digestive system and is characterized by poor prognosis and early metastasis. …”
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Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer by Larysa Poluben, Mannan Nouri, Jiaqian Liang, Shaoyong Chen, Andreas Varkaris, Betul Ersoy-Fazlioglu, Olga Voznesensky, Irene I. Lee, Xintao Qiu, Laura Cato, Ji-Heui Seo, Matthew L. Freedman, Adam G. Sowalsky, Nathan A. Lack, Eva Corey, Peter S. Nelson, Myles Brown, Henry W. Long, Joshua W. Russo, Steven P. Balk

“…Summary: Androgen receptor (AR) splice variants, of which ARv7 is the most common, are increased in castration-resistant prostate cancer, but the extent to which they drive AR activity is unclear. …”
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Tislelizumab in Chinese patients with advanced solid tumors: an open-label, non-comparative, phase 1/2 study by Lin Shen, Qing Zhou, Ting Sun, Jie Wang, Hongming Pan, Yi-Long Wu, Jun Zhao, Jun Guo, Qingyuan Zhang, Ying Yuan, Yuxian Bai, Tianshu Liu, Yongqian Shu, Siyang Wang, Aiping Zhou, Dingwei Ye, Yujuan Gao, Silu Yang, Zuobai Wang

“…Most treatment-related adverse events (62%) were grade 1 or 2, with the most common being anemia (n=70; 23%) and increased aspartate aminotransferase (n=67; 22%). …”
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Development of a Customizable Web-Based Dashboard for Remote Blood Pressure Monitoring: Feasibility and Usability Implementation Study by Joshua Wollen, Thuy Nguyen, Charles Coton, Gina DeWildt, Gabretta Cooksey, Audrey Cohen, Nicholas Hoang, Munachi Okpala, Michael Gonzalez, Mengxi Wang, Chigozirim Izeogu, Elmer Bernstam, Charles Green, Sean Savitz, Jose-Miguel Yamal, Anjail Sharrief

“…ObjectiveThis study aims to describe the development and design of a web-based EDC system tailored for remote BP monitoring and management to overcome common patient-, provider-, and system-specific challenges. …”
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Nonadherence to Diabetes Complications Screening in a Multiethnic Asian Population: Protocol for a Mixed Methods Prospective Study by Amudha Aravindhan, Eva Fenwick, Aurora Wing Dan Chan, Ryan Eyn Kidd Man, Wern Ee Tang, Ngiap Chuan Tan, Charumathi Sabanayagam, Junxing Chay, Lok Pui Ng, Wei Teen Wong, Wern Fern Soo, Shin Wei Lim, Ecosse L Lamoureux

“…Poor adherence to screening is common, but prospective data on the magnitude and predictors of nonadherence to DR, DN, and DFC screening in Singapore are unavailable. …”
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Investigating the Relationship between Changes in the Expression Level of the CLU Gene and the Prognosis of Gastric Cancer Patients by Arezoo Farhadi, Erfan Cheraghi, Nastaran Farahani, Fatemeh Khodabandehloo, Mohammad Foad Heidari, Reza Heydari, Mehdi Ghorbani, Mahmood Vahidi, Javad Behroozi

“…Background and purpose: Gastric cancer is one of the most common cancers, with over one million new cases annually, and is the second leading cause of cancer-related deaths worldwide, after lung cancer. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…This investigation was conducted within the framework of the interdisciplinary scientific program «Stress factors and mental disorders in rheumatic diseases». …”
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The state of the biogeometric profile of the posture of young athletes specializing in hand-to-hand combat as a prerequisite for the development of corrective and preventive measur... by Vitalii Kashuba, Аndrii Radchenko, Yuri Radchenko, Ilia Vako, Vitaly Usychenko

“…Results: It has been established that poor posture of various types is common among athletes aged 8-14 years, specializing in hand-to-hand combat, covering a contingent of 46.7 to 60% in different age groups. …”
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