Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Funding This award was funded by the National Institute for Health and Care Research (NIHR) Health Technology Assessment programme (NIHR award ref: 15/130/20) and is published in full in Health Technology Assessment; Vol. 29, No. 17. …”
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Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…Scientific summary Background In the UK, asthma remains a common medical condition affecting over 1 million children, one of the highest prevalence rates worldwide. …”
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Correlation of PD-L1 and HIF-1 Alpha Expression with KRAS Mutation and Clinicopathological Parameters in Non-Small Cell Lung Cancer by Seda Er Özilhan, Safa Can Efil, Doğukan Çanakçı, Yetkin Ağaçkıran, Didem Şener Dede, Nilüfer Onak Kandemir, Mehmet Doğan, Tuba Dilay Kökenek Ünal, Merve Meryem Kıran, Serra Kayaçetin, Hilal Balta, Hayriye Tatlı Doğan

“…<b>Background:</b> Lung cancer remains the leading cause of cancer-related deaths worldwide, with non-small cell lung carcinomas (NSCLCs) comprising the majority of cases. Among the common driver mutations, KRAS plays a critical role in guiding treatment strategies. …”
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Prevalence of Bacterial Pathogens Isolated from Canines with Pyoderma and Otitis Externa in Korea: A Systematic Review and Meta-Analysis by Maryum Tanveer, Eurade Ntakiyisumba, Fabrice Hirwa, Hakyoung Yoon, Sang-Ik Oh, Chongchan Kim, Mi Hye Kim, Ji-Seon Yoon, Gayeon Won

“…Publication bias was evaluated using funnel plots and Egger’s regression test, with all analyses conducted using the R program. Of the 944 articles, 29 met the eligibility criteria. …”
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Auricular acupressure promotes uterine involution after cesarean section: A randomized controlled trial by Shu-xin Wang, Jing-chun Zeng, Ting Li, Wan-lan Zhang, Yan-fang Li, Run-jin Zhou, Zi-jun Liu, Yu-ling Liu, Xun Zhuang, Rui Zhang, Li-ming Lu, Guo-hua Lin

“…Background: Postpartum subinvolution of the uterus is a more common condition after cesarean section. Auricular acupressure (AA) is widely used for the treatment of postpartum diseases. …”
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Association between executive functions and fear of falling among people aged 80 years or older: a cross-sectional study by Anna Awad, Anna Sundström, Felicia Gramner, Ursula Werneke, Annika Toots, Birgitta Olofsson, Albin Dahlin Almevall, Erik Rosendahl, Stefan Söderberg, Yngve Gustafson, Johan Niklasson

“…Abstract Objectives Fear of falling (FoF) is a common problem among older adults. It can lead to reduced quality of life and less physical activity, which increases fall risk. …”
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Sewage Sludge Biochar Improves Water Use Efficiency and Bean Yield in a Small-Scale Field Experiment with Different Doses on Sandy Soil Under Semiarid Conditions by Raví Emanoel de Melo, Vanilson Pedro da Silva, Diogo Paes da Costa, Maria Fernanda de A. Tenório Alves, Márcio Henrique Leal Lopes, Eline Dias Barbosa, José Henrique de Souza Júnior, Argemiro Pereira Martins Filho, Gustavo Pereira Duda, Antonio Celso Dantas Antonino, Maria Camila de Barros Silva, Claude Hammecker, José Romualdo de Sousa Lima, Érika Valente de Medeiros

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Somatostatin interneuron fate-mapping and structure in a Pten knockout model of epilepsy by Austin W. Drake, Austin W. Drake, Austin W. Drake, Lilian G. Jerow, Lilian G. Jerow, Justin V. Ruksenas, Carlie McCoy, Steve C. Danzer, Steve C. Danzer, Steve C. Danzer, Steve C. Danzer

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Validation of the Toronto recurrence inference using machine-learning for post-transplant hepatocellular carcinoma model by Zhihao Li, Itsuko Chih-Yi Chen, Leonardo Centonze, Christian T. J. Magyar, Woo Jin Choi, Tommy Ivanics, Grainne M. O’Kane, Arndt Vogel, Lauren Erdman, Luciano De Carlis, Jan Lerut, Quirino Lai, Vatche G. Agopian, Neil Mehta, Chao-Long Chen, Gonzalo Sapisochin

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Neuropsychiatric and laboratory outcomes of hepatitis C treatment in an early-treated HIV cohort in Thailand by Ferron Ocampo, Carlo Sacdalan, Suteeraporn Pinyakorn, Misti Paudel, Tanyaporn Wansom, Nathornsorn Poltubtim, Somchai Sriplienchan, Nittaya Phanuphak, Robert Paul, Denise Hsu, Donn Colby, Lydie Trautmann, Serena Spudich, Phillip Chan, the RV254/SEARCH 010 Study Team

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Descriptive characterization of measles in Kebbi State, Nigeria, 2013-2017 by Hashim Abdulmumin Bala, Mohammed Yahaya, Nyampa Barau, Lukman Surajudeen, Ismail Raji Abdullateef, Charles Rahab Amaza

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Comparative evaluation of three polymerase chain reaction primer sets for accurate molecular detection of Trypanosoma lewisi in wild rodents in Indonesia by Aditya Yudhana, Gusti Ayu Illiyin Putri Santosa, April Hari Wardhana, Frenky Laksana Putra, Ryanka Edila, Dyah Haryuningtyas Sawitri, Ratih Novita Praja, Muhammad Aqil Kurnianto, Aldi Gusnizar Rizaldy Tanjung, Marc Desquesnes, Makoto Matsubayashi

“…Background and Aim: Trypanosoma lewisi is a flea-transmitted protozoan parasite commonly infecting rodents and posing zoonotic risks. …”
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Design and validation of an energy level diary for fatigue management in patients with post-COVID syndrome by Maryam Balke, Maryam Balke, René Garbsch, René Garbsch, Jessica Cormann, Pantea Pape, Frank C. Mooren, Frank C. Mooren, Boris Schmitz, Boris Schmitz

“…Cognitive and motor fatigue are common clinical manifestations, limiting patients’ occupational, educational, and social activities severely.ObjectiveThis study aimed to develop a diary to keep record of daily changes in energy levels of patients with PCS to adapt their rehabilitation program.Material and methodsWe conducted a prospective observational study at two German rehabilitation centers in a codesign approach with repeated feedback loops. …”
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Delineating urban flooding when incorporating community stormwater knowledge by Madeline Scolio, Peleg Kremer, Virginia Smith, Achira Amur, Bridget Wadzuk, Kate Homet, Eric Devlin, Md Abdullah Al Mehedi, Laura Moore

“…Community stormwater knowledge is a powerful tool that can be used as a complement to hydrologic flood delineation techniques to overcome common limitations in urban landscapes.…”
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PhotoNeuro: A compact photodetector for synchronization of visual stimulus presentation during behavioural experiments in neuroscience by Xavier Cano-Ferrer, Marcelo J. Moglie, George Konstantinou, Antonin Blot, Gaia Bianchini, Albane Imbert, Petr Znamenskiy, M. Florencia Iacaruso

“…Here, we present a compact, low-cost photodetector system designed for compatibility with common 3.3–5 V microcontroller-based development boards (e.g., Arduino) and the open-source visual programming language Bonsai, widely used in neuroscience for experiment control. …”
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Trade-off between resistance and persistence in high cell density cultures by F. Beulig, J. Bafna-Rührer, P. E. Jensen, S. H. Kim, A. Patel, V. Kandasamy, C. Steffen, K. Decker, D. Zielinski, L. Yang, E. Özdemir, S. Sudarsan, B. Palsson

“…This study deepens our understanding of high-density physiology, illustrates a common link between biomanufacturing and infection, and suggests that persistence phenotypes are programmed as hidden transcriptional states in E. coli.IMPORTANCEThis study presents the first systems-level characterization of Escherichia coli high-cell-density physiology, using an integrated experimental and computational approach. …”
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Genome wide identification and characterization of Bax inhibitor-1 gene family in cucumber (Cucumis sativus) under biotic and abiotic stress by Samia Anwar, Riffat Siddique, Shakeel Ahmad, Muhammad Zeshan Haider, Haider Ali, Adnan Sami, Rosa Sanchez Lucas, Muhammad Shafiq, Bader Un Nisa, Bilal Javed, Jannat Akram, Javaria Tabassum, Muhammad Arshad Javed

“…These genes share conserved domains, indicating common evolutionary history and function. Physicochemical analysis revealed their molecular weights and isoelectric points, while subcellular localization showed their presence in different cellular compartments. …”
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Incidence trends of non-Hodgkin lymphoma in children in the United States from 2000 to 2020 by Seyed Ehsan Mousavi, Kimia Motlagh Asghari, Armin Aslani, Farzin Tahmasbi Arashlow, Zahra Yekta, Seyed Aria Nejadghaderi

“…Results: From 2000 to 2019, there were 38,098 reported cases of pediatric NHL, with B-cell NHL being the most common subtype (84.31 %). Most cases were observed in non-Hispanic Whites (46.71 %) and children aged ≤4 years (37.26 %). …”
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Indicators of Quality of Clinical Care for Type 2 Diabetes Patients in Primary Health Care Centers in Qatar: A Retrospective Analysis by Saleh Attal, Mohamed H. Mahmoud, Muna Taher Aseel, Ady Candra, Paul Amuna, Mohamed Elnagmi, Mostafa Abdallah, Nahed Ismail, Ahmed Abdelrazek, Dia Albaw, Abdulsalam Albashir, Hisham Elmahdi

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Prevalence, Awareness, Treatment, Control, and Related Factors of Hypertension among Tajik Nomads Living in Pamirs at High Altitude by Lin Wang, Nanfang Li, Mulalibieke Heizhati, Suofeiya Abulikemu, Delian Zhang, Qin Luo, Ling Zhou, Jing Hong, Junli Hu, Li Cai, Xin Zhao, Le Sun, Liang Shao

“…Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers were the most commonly used antihypertensive medication (45.4%) as monotherapy, and 13.6% of treated hypertensive patients used two drugs. …”
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