Planning a Clinical Development Programme for Medicinal Products for Irritable Bowel Syndrome: An Analysis of the European Medicines Agency’s Recommendations by E. A. Gerasimets, N. A. Rumyantsev, R. S. Ilin, D. V. Goryachev

“…The intensification of drug development aimed at improving the safety and efficacy of IBS therapy in the context of the growing common pharmaceutical market of the Eurasian Economic Union (EAEU) requires guidelines for planning and conducting clinical trials of medicinal products for IBS.AIM. …”
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Evaluation of Government Programmes on Enhancing the Lives of the Elderly: A Case Study of Social Assistance Grant for Empowerment in Mitooma District. by Natuha, Prossy

“…The study was about evaluating government programmes on enhancing the lives of the elderly: A case study of social assistance grant for empowerment in Mitooma District, Uganda. …”
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Impact evaluation of a social protection programme paired with fee waivers on enrolment in Ghana’s National Health Insurance Scheme by Tia M Palermo, Clare Barrington, Elsa Valli, Gustavo Ángeles-Tagliaferro, Marlous de Milliano, Clement Adamba, Tayllor Renee Spadafora, Tia Palermo, Richard de Groot, Isaac Osei-Akoto, Joseph K. Darko, Robert Darko Osei, Francis Dompae, Nana Yaw, Gustavo Angeles, Sudhanshu Handa, Frank Otchere, Marlous de Miliano, Akalpa J Akaligaung, Raymond Aborigo

“…Common reasons for not enrolling were fees and travel.Conclusion While impacts on NHIS enrolment were significant, gaps remain to maximise the potential of integrated programming. …”
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First Dental Steps intervention: feasibility study of a health visitor led infant oral health improvement programme by Joanna G. Williams, Patricia Nicole Albers, Sarab El-Yousfi, Zoe Marshman, Reena Patel, Alice Porter, Katrina d’Apice, Katie Breheny, Frank de Vocht, Chris Metcalfe, Robert Witton, Ruth Kipping

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A home-based exercise programme attenuates fatigue in primary biliary cholangitis: Results from the EXCITED clinical trial by Alice Freer, Felicity R. Williams, Simon Durman, Jennifer Hayden, Matthew J. Armstrong, Palak J. Trivedi

“…Background & Aims: Fatigue is a commonly reported symptom of primary biliary cholangitis (PBC). …”
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Reducing time for vascular access salvage: initial results from a single institution’s clinical practice improvement programme by Li Zhang, Malcolm Han Wen Mak, Ying Pan, Enhui Yong, Pua Uei, Justin Kwan, Enming Yong, Kai Siang Chan, Shufen Neo, Xueping Zhou, Joana Marie Eugenio Gray, Diomampo Katriz Abanto Elah, Ee Ling Ong, Qiantai Hong, Lester Rhan Chaen Chong, Glenn Wei Leong Tan, Sundeep Punamiya, Gavin Lim, Gabriel Chan, Krishna Gummalla, Lawrence Han Hwee Quek, Bien Peng Tan

“…Background One of the most common causes of arteriovenous fistula (AVF) and/or arteriovenous graft (AVG) failure is thrombosis. …”
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Developmental programming of cardiovascular dysfunction by prenatal hypoxia and oxidative stress. by Dino A Giussani, Emily J Camm, Youguo Niu, Hans G Richter, Carlos E Blanco, Rachel Gottschalk, E Zachary Blake, Katy A Horder, Avnesh S Thakor, Jeremy A Hansell, Andrew D Kane, F B Peter Wooding, Christine M Cross, Emilio A Herrera

“…Fetal hypoxia is a common complication of pregnancy. It has been shown to programme cardiac and endothelial dysfunction in the offspring in adult life. …”
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Piloting the options assessment toolkit with national malaria programme leaders from the Asia–Pacific countries: a meeting report by Manash Shrestha, Sanjaya Acharya, Josselyn Neukom, Karma Lhazeen, Ngo Duc Thang, Muhammad Naeem Habib, Lyndes Wini, Tobgyel Tobgyel, Kesang Wangchuk, Huy Rekol, Lek Dysoley, Siv Sovannaroth, Minerva Simatuopang, Helen Dewi Prameswari, Asik Surya, Zau Ring, Mohammad Qasim Khan, Boualam Khamlome, Mohd Hafizi Abdul Hamid, Ram Kumar Mahato, Top Thapa, Sheen Angelou Juangco, Hee Il Lee, Hyun Il Shin, Kumudu Gunasekera, Champa Aluthwera, Prayuth Sudathip, Rungrawee Timpontree, Hoang Dinh Canh, Sonia Cheung, Muhammad Zeeshan Haroon, Shreehari Acharya, Robert J. Commons, Bipin Adhikari, Varunika Ruwanpura, Phone Si Hein, Abhijit Sharma, Poe Poe Aung, Neena Valecha, Kamala Thriemer, Caroline A. Lynch

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Unmet needs in adult patients with ulcerative colitis in Spain: a real-world Adelphi Disease Specific Programme study by Ignacio Marín-Jiménez, Itxaso Aguirregabiria, Silvia Díaz-Cerezo, Sebastián Moyano, Hugo Gabilondo, Hannah Knight, Niamh Harvey, Theresa Hunter Gibble, Pilar Nos

“…Among patients classified as having moderate-to-severe UC, commonly reported symptoms included abdominal pain (41%), bowel urgency (37%), and bloody diarrhea (37%). …”
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Improved population coverage of the human papillomavirus vaccine after implementation of a school-based vaccination programme: the Singapore experience by Karuppiah Vijayalakshmi, Anne Hui Yi Goei

“…This model can be applied to future school health programmes.…”
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Optimal control of hepatitis C antiviral treatment programme delivery for prevention amongst a population of injecting drug users. by Natasha K Martin, Ashley B Pitcher, Peter Vickerman, Anna Vassall, Matthew Hickman

“…Previous modelling studies have shown antiviral treatment for active IDUs could reduce HCV prevalence, and there is emerging interest in developing targeted IDU treatment programmes. However, the optimal timing and scale-up of treatment is unknown, given the real-world constraints commonly existing for health programmes. …”
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Second-line antiretroviral therapy in a workplace and community-based treatment programme in South Africa: determinants of virological outcome. by Victoria Johnston, Katherine Fielding, Salome Charalambous, Mildred Mampho, Gavin Churchyard, Andrew Phillips, Alison D Grant

“…Following switch, 48.3% (workplace) and 72.0% (community) achieved VL<400, with non-adherence (17.9% vs. 1.4%) and virological rebound (35.6% vs. 13.2% with available measures) reported more commonly in the workplace programme. In adjusted analysis of the workplace programme, lower switch VL and younger age were associated with VL<400. …”
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Patient and public involvement in preclinical and medical research: Evaluation of an established programme in a Discovery‐Based Medical Research Institute by Robyn A. Smith, Judith Slocombe, Jo Cockwill, Kathy Minas, George Kiossoglou, Katya Gray, William Lawrence, Michelle Iddles, Clare Scott, Lorraine A. O'Reilly

“…Few formal evaluations of these programmes are reported in the literature. Objective This study aimed to evaluate an established patient and public involvement programme operating in a major Australian Discovery‐Based Medical Research Institute (DBMRI) to inform programme development and the wider field. …”
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Microbiological and Nutritional Characteristics of Locally Fermented Fufu Commonly Sold in Amai, Delta State, Nigeria by C. S. Akpeji, D. U. Ewetan, B. O. Bosah, C. C. Otali, C. O. Ossai

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The Otolaryngology boot camp: a scoping review evaluating commonalities and appraisal for curriculum design and delivery by Adom Bondzi-Simpson, C. J. Lindo, Monica Hoy, Justin T. Lui

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Practice of community-service doctors in the assessment and medico-legal documentation of common physical assault cases by L Fouché, J Bezuidenhout, C Liebenberg, A O Adefuye

“…This study investigates the practice of CSDs in relation to the assessment and medico-legal documentation of allegations of common assault, with a view to identifying gaps in their knowledge of clinical forensic medicine. …”
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Imposter Syndrome Among Orthopaedic Surgery Residents is Extremely Common and Disproportionately Affects Female Residents by Harsh Wadhwa, MD, Harmon S. Khela, BS, Monty S. Khela, BA, Noelle Van Rysselberghe, MD, Anastasia A. Hunt, MD, Laura Lu, MD, Julius Bishop, MD

“…Imposter syndrome is common among orthopaedic surgery residents, with 73% experiencing significant or intense symptoms. …”
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Genomic insights into genetic diversity and seed coat color change in common bean composite populations by Eva Plestenjak, Eva Plestenjak, Mohamed Neji, Lovro Sinkovič, Vladimir Meglič, Barbara Pipan

“…The strong genetic differentiation between standard varieties and composite populations highlights the role of selective breeding in shaping the genetic landscape of common bean. The results suggest that variation in seed coat color is controlled by both regulatory and structural genetic changes, providing valuable information for breeding programs.ConclusionThis study provides a detailed analysis of the genetic architecture of seed coat color variation in common bean. …”
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Augmenting Parenting Programs With the Pause Mobile App: Mixed Methods Evaluation by Nathan Hodson, Peter Ivor Woods, Stephanie Donohoe, Juan Luque Solano, James Gardner, Manuel Giardino, Michael Sobolev, Domenico Giacco

“… BackgroundParenting programs are the recommended treatment for common mental health problems of childhood such as conduct disorder. …”
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Implementation of a life quality program in a retail company by Maria Elisa Gonzalez Manso

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