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Extracellular vesicles derived from mature dendritic cells loaded with cDC1-specific chemokine XCL1 combined with chemotherapy-induced ICD for the treatment of castration-resistant...
Published 2025-06-01“…This approach offers a new strategy and preclinical evidence for the immunotherapy of “cold tumors” prostate cancer.…”
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142
ZmNF-YB10, a maize NF-Y transcription factor, positively regulates drought and salt stress response in Arabidopsis thaliana
Published 2025-12-01“…The results indicated that the gene was 1209 base pairs (bp) in length, with a coding sequence (CDS) region of 618 bp, encoding a polypeptide composed of 205 amino acid residues. …”
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143
Adulteration detection in cactus seed oil: Integrating analytical chemistry and machine learning approaches
Published 2025-01-01“…Therefore, combining MC simulation with RF as a robust method for detecting CO adulteration is proposed. The proposed method, coded in Python and available as open-source, offers a flexible framework for continuous adaptation with new data.…”
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144
Genome-wide identification and characterization of the CCT gene family in Chinese cabbage (Brassica rapa) response to abiotic stress
Published 2025-07-01“…Quantitative real-time polymerase chain reaction (qRT-PCR) analysis of ten CCT genes confirmed their response to heat stress, cold stress, drought stress, and abscisic acid stress. …”
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145
Evolutionary dynamics of the calcium/cation antiporter superfamily in Brassicaceae: codon usage, selection pressure, and BnCaCAs role in abiotic stress response
Published 2025-07-01“…Comprehensive analyses of their coding proteins physicochemical properties, subcellular localization, conserved motifs, and gene structures were performed. …”
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146
Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas
Published 2025-01-01“…Surfactant-associated 3 (SFTA3), a long non-coding RNA predominantly expressed in normal lung epithelial cells, plays a crucial role in lung development. …”
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147
Overexpression of ornithine decarboxylase 1 mediates the immune-deserted microenvironment and poor prognosis in diffuse large B-cell lymphoma
Published 2025-02-01“…Genomic analysis revealed widespread copy number losses in the chemokine and interferon coding regions 8p23.1 and 9p21.3 in HRG. We identified ODC1 as a therapeutic vulnerability for HRG-DLBCL. …”
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148
Assessment of Antimycobacterial Activity of Newly Synthesized Pyrimidine Derivatives Against Mycobacterium tuberculosis
Published 2022-08-01“…A 4-week culture of M.tuberculosis, synchronized by cold (+4°C) for 72 hours, was used to prepare a suspension of mycobacteria. …”
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149
7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas
Published 2025-04-01“…The lack of ICIs efficacy in GBM is attributed to the accumulation of tumor-reprogrammed glioma-associated myeloid cells (GAMs) that create a “cold” immunosuppressive tumor microenvironment (TME), impeding the infiltration and activation of effector T cells. …”
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150
Adolescent vaccine introductions scoping review: A decade of insights from low- and middle-income countries (2013−2023)
Published 2025-08-01“…We further searched the citations of included articles. We coded included articles for key characteristics and analyzed for thematic commonalities. …”
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151
Semantic representation of anarchist thought in contemporary feature films
Published 2025-08-01“…The idea of anarchism grows in the film and is represented by the use of double codes as techniques whose connotations are intertwined in the structure of the femme narration. 2. …”
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152
Selection of suitable reference lncRNAs for gene expression analysis in Osmanthus fragrans under abiotic stresses, hormone treatments, and metal ion treatments
Published 2025-01-01“…Despite its importance, research on long non-coding RNAs (lncRNAs) in O. fragrans has been constrained by the absence of reliable reference genes (RGs).MethodsWe employed five distinct algorithms, i.e., delta-Ct, NormFinder, geNorm, BestKeeper, and RefFinder, to evaluate the expression stability of 17 candidate RGs across various experimental conditions.Results and discussionThe results indicated the most stable RG combinations under different conditions as follows: cold stress: lnc00249739 and lnc00042194; drought stress: lnc00042194 and lnc00174850; salt stress: lnc00239991 and lnc00042194; abiotic stress: lnc00239991, lnc00042194, lnc00067193, and lnc00265419; ABA treatment: lnc00239991 and 18S; MeJA treatment: lnc00265419 and lnc00249739; ethephon treatment: lnc00229717 and lnc00044331; hormone treatments: lnc00265419 and lnc00239991; Al3+ treatment: lnc00087780 and lnc00265419; Cu2+ treatment: lnc00067193 and 18S; Fe2+ treatment: lnc00229717 and ACT7; metal ion treatment: lnc00239991 and lnc00067193; flowering stage: lnc00229717 and RAN1; different tissues: lnc00239991, lnc00042194, lnc00067193, TUA5, UBQ4, and RAN1; and across all samples: lnc00239991, lnc00042194, lnc00265419 and UBQ4. …”
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153
Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT
Published 2025-05-01“…Overall, the number of adverse reactions was also similar between groups; there was an excess of adverse reactions coded ‘vascular disorders’ in the bisoprolol group. …”
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154
The near-complete genome assembly of Ampelopsis grossedentata provides insights into its origin, evolution, and the regulation of flavonoid biosynthesis
Published 2025-08-01“…The dried stems, leaves, and shoot tips, known as “vine tea,” are consumed as a health beverage and traditional remedy for colds and fever. In this study, we assembled a near-complete reference genome of A. grossedentata spanning 555.42 Mb, where Hi-C-based correction resolved 18 out of its 20 chromosomes into gap-free assemblies. …”
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155
The Effect of Serish Root Gum (Eremurus luteus) as Fat Replacer on Rheological, Physical and Sensory Properties of Low Fat Ice Cream
Published 2025-05-01“…In the sensory evaluation section, the characteristics of creaminess, sweetness, viscosity, roughness, coldness and hardness were evaluated by transient dominant sensation test and these changes were significant in most cases. …”
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