The role of cyclooxygenase-2 (COX-2) and inflammatory markers in the progress of Alport syndrome in Egyptian children by Moushira Zaki, Hisham A. Orban, Mohamed A. Shahba, Rehab S. I. Moustafa, Ahmed Adel, Fatina I. Fadel, Abeer Selim, Hala T. El-Bassyouni, Eman R. Youness

Get full text

Subclinical systolic dysfunction in children with steroid-resistant nephrotic syndrome identified by speckle tracking echocardiography by Mohamed Hashem Mahgoob, Amr Mostafa Setouhi

“…Multiple binary regression analysis for the predictors of systolic dysfunction in SRNS patients revealed that the serum albumin is the only variable that predicts systolic dysfunction in these children. …”
Get full text

The role of adhesion molecules in inflammatory bowel disease in children. Assessment of the possible risk of cardiovascular complications by Aneta Trzeciak-Jędrzejczyk, Ryszard Makosiej, Michał Kolejwa, Ewa Głowacka, Elżbieta Czkwianianc

“…Aim : To assess the risk of atherosclerosis in IBD in children. Material and methods : The study included 40 patients with IBD (25 with Crohn’s disease – CD and 15 with ulcerative colitis – UC) aged 4–17 years. …”
Get full text

Measuring Measuring iron concentration in the blood samples of some autistic children from Baghdad City by Ezzuldin sulaiman, Hind Suhail Abdulhay

“…This study aimed to measure iron levels in samples of autistic children in Baghdad City. Blood serum samples were collected from 60 patients with autism spectrum disorder and 35 healthy controls to measure iron levels. …”
Get full text

Acute Abdomen as a Clinical Presentation of COVID-19-Associated Multisystem Inflammatory Syndrome in Children by Elmira Hajiesmaeil Memar, Fatemeh Tahghighi, Sedigheh Yousefzadegan, Parisa Sadeghirad, Ashraf Mousavi, Ramin Zare Mahmoudabadi, Hossein Saeidi, Mehri Ayati, Sahar Naderi, Sara Memarian, Seyedmusa Zeinalabedin, Bahar Ashjaei, Hojatollah Raji, Leila Tahernia, Hosein Alimadadi, Vahid Ziaee

“…Multisystem inflammatory syndrome in children (MIS-C) due to cytokine release syndrome following COVID-19 presents with various manifestations. …”
Get full text

Early Markers of Liver Fibrosis in Children with Beta-thalassaemia Major: A Cross-sectional Study by Himani Aggarwal, Monica Verma, Shuchi Bhalla, Dinkar Yadav, Kapil Bhalla, Abhishek Soni

“…Early markers for liver fibrosis were evaluated using serum YKL-40 levels, APRI, and FIB-4 scores, which were then compared to fibrosis scores obtained from TE. …”
Get full text

Understanding secondary hypogammaglobulinemia and its implications for cancer prognosis in children: A retrospective cohort study by Ana Lucía Guzmán, Isabella Villamil, Sofía Martínez-Betancur, Oriana Arias-Valderrama, Jacobo Triviño-Arias, Jessica Largo, Viviana Lotero, Alexis Franco, Ximena Castro, Pamela Rodríguez, Luz Angela Urcuqui, Diego Medina, Manuela Olaya

Get full text

Correlation of serum Vitamin D levels and disease severity in patients with atopic dermatitis: A hospital-based, cross-sectional study from North India by Shreya Malhan, Loveleen Kaur, Maninder Kaur, Dimple Chopra, Sharang Gupta, Snehdeep Kaur

“…AIMS AND OBJECTIVES: This study was designed to determine the serum levels of Vitamin D in children with AD and to establish a correlation between serum Vitamin D levels and disease severity. …”
Get full text

Sex Hormones in Allergic Conjunctivitis: Altered Levels of Circulating Androgens and Estrogens in Children and Adolescents with Vernal Keratoconjunctivitis by Marta Sacchetti, Alessandro Lambiase, Costanzo Moretti, Flavio Mantelli, Stefano Bonini

“…To evaluate a possible role of sex hormones in VKC, serum levels of sex hormones in children and adolescents with VKC were assessed. …”
Get full text

Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study by Mehryar Mehrkash, Seyed-javad Golestaneh, Yahya Madihi, Fatemeh Paknazar, Mahdi Hadian, Mojtaba Akbari, Bahareh Abtahi-Naeini

“…Conclusion. Increased level of serum Ca and higher age were associated with increased odds of having more severe pruritus score in children.…”
Get full text

Anthropometric and Biochemical Profile of Children and Adolescents with Chronic Kidney Disease in a Predialysis Pediatric Interdisciplinary Program by Vanessa R. Silva, Cristina B. Soares, Juliana O. Magalhães, Isabella Peixoto de Barcelos, Debora C. Cerqueira, Ana Cristina Simões e Silva, Eduardo A. Oliveira

“…This is longitudinal retrospective observational cohort study that evaluated anthropometric and biochemical variables of children and adolescents admitted to a Predialysis Interdisciplinary Management Program (PDIMP) responsible for the follow-up of children and adolescents at stages 2 to 4 of chronic kidney disease (CKD) at a tertiary center. …”
Get full text

Impact of Different Metabolic Indicators on Ventricular Repolarization Indices in Obese Children: A Case Control Study by Asmaa A El Sehmawy, Rasha Abd El Samad Fawaz, Nadia Ahmed Agiba, Eman Aziz Elsherbiny, Nglaa Fathi Agaba, Doaa Sayed Mohammed, Haidy Mahmoud Nasr, Fatma Elzhraa AE Diab, Amal M Ahmed, Shorouk Issa Mahfouz, Heba T Okda, Doaa Sadek Ahmed

“…Results: Obese children had significantly higher serum levels of triglycerides, cholesterol, LDL, fasting insulin, and HOMA-IR compared to controls. …”
Get full text

Changes in blood glucose and lipid metabolism levels in children with central precocious puberty and its correlation with obesity by Xin Cui, Xin Cui, Xin Sun, Qiubo Li, Zongbo Chen

“…ObjectiveThis study analyzed the changes in blood glucose and lipid metabolism levels in children with central precocious puberty (CPP) and the correlation between CPP and obesity.MethodsIn total, 88 children with CPP aged 6–10 years who were admitted to our hospital between January 2023 and June 2024 (the CPP group), and 88 children without CPP in the same age group who received health check-ups (the non-CPP group) were retrospectively enrolled in this study. …”
Get full text

Effect of exposure to environmental phenols and parabens on folate concentrations among 3–19 years old children and adolescents: A cross-sectional study in NHANES 2005–2016 by Meng Ni, Zhenying Lin, Ze Chen, Ziwen Xu, Qianqian Zhang, Jiuru Zhao, Wei Li, Yanan Tang, Zelin Cao, Baihe Li, Dongting Yao, Chunyu Cheng, Yi Hu, Xiaorui Liu, Jiji Chen, Zhiwei Liu

“…Similar associations were found with serum folate. The weighted quantile sum index showed a decrease in both RBC and serum folate levels with an increase in the mixture of phenols and parabens. …”
Get full text

Prevalence of peripheral neuropathy in children with transfusion-dependent thalassemia: A hospital-based cross-sectional study by Aniruddha Rathore, Mukesh Dhankar, Sharmila B. Mukherjee, Suvasini Sharma, Shailaja Shukla, Piali Mandal

“…Background: Our study aimed to determine the prevalence of Peripheral Neuropathy (using nerve conduction studies (NCS)) in children with transfusion-dependent thalassemia aged between 5 to 18 years and to study its correlation with chronic anemia, ferritin levels, chelation status, annual transfusion requirement, deficiency of serum Vitamin B12, and Folate levels. …”
Get full text

A systematic review and meta-analysis of correlation between cough variant asthma and mycoplasma pneumonia in children by Luyan Jiao, Guoqing Zhang, Yi Yuan, Ling Cao

“…The results of the heterogeneity test suggested that the serum level of IgE (MD = 80.69, 95% CI: 77.75–83.62, p < 0.001; p for heterogeneity < 0.001, I 2 = 95%), eosinophil count (MD = 2.93, 95% CI: 2.72–3.13, p < 0.001; p for heterogeneity < 0.001, I 2 = 71%) and the number of children with positive IgM (OR = 4.44, 95% CI: 3.73–5.29, p < 0.001; p for heterogeneity = 0.63, I 2 = 0%) were significantly different. …”
Get full text

NGAL as an Early Predictive Marker of Diabetic Nephropathy in Children and Young Adults with Type 1 Diabetes Mellitus by Nektaria Papadopoulou-Marketou, Alexandra Margeli, Ioannis Papassotiriou, George P. Chrousos, Christina Kanaka-Gantenbein, Jeanette Wahlberg

“…Serum concentrations of NGAL (ELISA) were determined, and SAP and DAP were examined (SAP and DAP also expressed as z-scores in the younger group). …”
Get full text

The effectiveness of ERCP in managing preoperative complications of choledochal cysts in children and its role in facilitating early surgical intervention by Tian Zhang, Wenjie Wu, Yijun Shu, Hao Weng, Mingzhe Weng, Ying Zhou, Xuefeng Wang

“…Significant improvements were observed in serum amylase levels and liver function tests following ERCP. …”
Get full text

Reference Intervals (RIs) of the Bone Turnover Markers (BTMs) in Children and Adolescents: A Proposal for Effective Use by Vincenzo Brescia, Roberto Lovero, Antonietta Fontana, Roberta Zerlotin, Silvia Concetta Colucci, Maria Grano, Angela Pia Cazzolla, Francesca Di Serio, Vito Crincoli, Maria Felicia Faienza

“…The aim of this study was to establish the RI for the BTM [specific bone alkaline phosphatase (BALP), carboxy-terminal cross-linked collagen type I telopeptide (CTX), N-terminal propeptide pro-collagen type I (PINP), osteocalcin (OC), resistant to acid tartrate phosphatase isoform 5b (TRAcP-5b)] on serum samples from children and adolescents. Method: 202 samples from children and adolescents (ages 1–18 years) (51.48% male), considered apparently healthy. …”
Get full text

Oxycodone for analgesia in children undergoing endoscopic retrograde cholangiopancreatography: a randomized, double-blind, parallel study by Wei Ji, Wei Ji, Liping Sun, Liping Sun, Yue Huang, Yue Huang, Jie Bai, Jie Bai, Jijian Zheng, Jijian Zheng, Kan Zhang, Kan Zhang

“…Additionally, inflammatory cytokines in the serum, including tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10 were examined by blood sampling at baseline, 6 h, and 24 h after ERCP.ResultsCompared to fentanyl, children receiving oxycodone had significantly lower pain scores at 30 min, 6 h, and 24 h after ERCP, while the scores at 10 and 20 min were similar in both groups. …”
Get full text