Subclinical systolic dysfunction in children with steroid-resistant nephrotic syndrome identified by speckle tracking echocardiography by Mohamed Hashem Mahgoob, Amr Mostafa Setouhi

“…Multiple binary regression analysis for the predictors of systolic dysfunction in SRNS patients revealed that the serum albumin is the only variable that predicts systolic dysfunction in these children. …”
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Diagnostic Value of Dynamics Serum sCD163, sTREM-1, PCT, and CRP in Differentiating Sepsis, Severity Assessment, and Prognostic Prediction by Longxiang Su, Lin Feng, Qing Song, Hongjun Kang, Xingang Zhang, Zhixin Liang, Yanhong Jia, Dan Feng, Changting Liu, Lixin Xie

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Measuring Measuring iron concentration in the blood samples of some autistic children from Baghdad City by Ezzuldin sulaiman, Hind Suhail Abdulhay

“…This study aimed to measure iron levels in samples of autistic children in Baghdad City. Blood serum samples were collected from 60 patients with autism spectrum disorder and 35 healthy controls to measure iron levels. …”
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Acute Abdomen as a Clinical Presentation of COVID-19-Associated Multisystem Inflammatory Syndrome in Children by Elmira Hajiesmaeil Memar, Fatemeh Tahghighi, Sedigheh Yousefzadegan, Parisa Sadeghirad, Ashraf Mousavi, Ramin Zare Mahmoudabadi, Hossein Saeidi, Mehri Ayati, Sahar Naderi, Sara Memarian, Seyedmusa Zeinalabedin, Bahar Ashjaei, Hojatollah Raji, Leila Tahernia, Hosein Alimadadi, Vahid Ziaee

“…Multisystem inflammatory syndrome in children (MIS-C) due to cytokine release syndrome following COVID-19 presents with various manifestations. …”
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Understanding secondary hypogammaglobulinemia and its implications for cancer prognosis in children: A retrospective cohort study by Ana Lucía Guzmán, Isabella Villamil, Sofía Martínez-Betancur, Oriana Arias-Valderrama, Jacobo Triviño-Arias, Jessica Largo, Viviana Lotero, Alexis Franco, Ximena Castro, Pamela Rodríguez, Luz Angela Urcuqui, Diego Medina, Manuela Olaya

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Effect of exposure to environmental phenols and parabens on folate concentrations among 3–19 years old children and adolescents: A cross-sectional study in NHANES 2005–2016 by Meng Ni, Zhenying Lin, Ze Chen, Ziwen Xu, Qianqian Zhang, Jiuru Zhao, Wei Li, Yanan Tang, Zelin Cao, Baihe Li, Dongting Yao, Chunyu Cheng, Yi Hu, Xiaorui Liu, Jiji Chen, Zhiwei Liu

“…Similar associations were found with serum folate. The weighted quantile sum index showed a decrease in both RBC and serum folate levels with an increase in the mixture of phenols and parabens. …”
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A systematic review and meta-analysis of correlation between cough variant asthma and mycoplasma pneumonia in children by Luyan Jiao, Guoqing Zhang, Yi Yuan, Ling Cao

“…The results of the heterogeneity test suggested that the serum level of IgE (MD = 80.69, 95% CI: 77.75–83.62, p < 0.001; p for heterogeneity < 0.001, I 2 = 95%), eosinophil count (MD = 2.93, 95% CI: 2.72–3.13, p < 0.001; p for heterogeneity < 0.001, I 2 = 71%) and the number of children with positive IgM (OR = 4.44, 95% CI: 3.73–5.29, p < 0.001; p for heterogeneity = 0.63, I 2 = 0%) were significantly different. …”
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The effectiveness of ERCP in managing preoperative complications of choledochal cysts in children and its role in facilitating early surgical intervention by Tian Zhang, Wenjie Wu, Yijun Shu, Hao Weng, Mingzhe Weng, Ying Zhou, Xuefeng Wang

“…Significant improvements were observed in serum amylase levels and liver function tests following ERCP. …”
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Sex Hormones in Allergic Conjunctivitis: Altered Levels of Circulating Androgens and Estrogens in Children and Adolescents with Vernal Keratoconjunctivitis by Marta Sacchetti, Alessandro Lambiase, Costanzo Moretti, Flavio Mantelli, Stefano Bonini

“…To evaluate a possible role of sex hormones in VKC, serum levels of sex hormones in children and adolescents with VKC were assessed. …”
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Pruritus Features in Children with End-Stage Renal Disease Underwent Dialysis: A Cross-Sectional Study by Mehryar Mehrkash, Seyed-javad Golestaneh, Yahya Madihi, Fatemeh Paknazar, Mahdi Hadian, Mojtaba Akbari, Bahareh Abtahi-Naeini

“…Conclusion. Increased level of serum Ca and higher age were associated with increased odds of having more severe pruritus score in children.…”
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Anthropometric and Biochemical Profile of Children and Adolescents with Chronic Kidney Disease in a Predialysis Pediatric Interdisciplinary Program by Vanessa R. Silva, Cristina B. Soares, Juliana O. Magalhães, Isabella Peixoto de Barcelos, Debora C. Cerqueira, Ana Cristina Simões e Silva, Eduardo A. Oliveira

“…This is longitudinal retrospective observational cohort study that evaluated anthropometric and biochemical variables of children and adolescents admitted to a Predialysis Interdisciplinary Management Program (PDIMP) responsible for the follow-up of children and adolescents at stages 2 to 4 of chronic kidney disease (CKD) at a tertiary center. …”
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Impact of Different Metabolic Indicators on Ventricular Repolarization Indices in Obese Children: A Case Control Study by Asmaa A El Sehmawy, Rasha Abd El Samad Fawaz, Nadia Ahmed Agiba, Eman Aziz Elsherbiny, Nglaa Fathi Agaba, Doaa Sayed Mohammed, Haidy Mahmoud Nasr, Fatma Elzhraa AE Diab, Amal M Ahmed, Shorouk Issa Mahfouz, Heba T Okda, Doaa Sadek Ahmed

“…Results: Obese children had significantly higher serum levels of triglycerides, cholesterol, LDL, fasting insulin, and HOMA-IR compared to controls. …”
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NGAL as an Early Predictive Marker of Diabetic Nephropathy in Children and Young Adults with Type 1 Diabetes Mellitus by Nektaria Papadopoulou-Marketou, Alexandra Margeli, Ioannis Papassotiriou, George P. Chrousos, Christina Kanaka-Gantenbein, Jeanette Wahlberg

“…Serum concentrations of NGAL (ELISA) were determined, and SAP and DAP were examined (SAP and DAP also expressed as z-scores in the younger group). …”
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Reference Intervals (RIs) of the Bone Turnover Markers (BTMs) in Children and Adolescents: A Proposal for Effective Use by Vincenzo Brescia, Roberto Lovero, Antonietta Fontana, Roberta Zerlotin, Silvia Concetta Colucci, Maria Grano, Angela Pia Cazzolla, Francesca Di Serio, Vito Crincoli, Maria Felicia Faienza

“…The aim of this study was to establish the RI for the BTM [specific bone alkaline phosphatase (BALP), carboxy-terminal cross-linked collagen type I telopeptide (CTX), N-terminal propeptide pro-collagen type I (PINP), osteocalcin (OC), resistant to acid tartrate phosphatase isoform 5b (TRAcP-5b)] on serum samples from children and adolescents. Method: 202 samples from children and adolescents (ages 1–18 years) (51.48% male), considered apparently healthy. …”
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Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Peripheral Blood Leukocytes and Plasma of Children with Nonalcoholic Fatty Liver Disease by Joanna B. Trojanek, Jacek Michałkiewicz, Renata Grzywa-Czuba, Wojciech Jańczyk, Lidia Gackowska, Izabela Kubiszewska, Anna Helmin-Basa, Aldona Wierzbicka-Rucińska, Mieczysław Szalecki, Piotr Socha

“…The MMP-9, TIMP-2 expression levels, plasma amounts of MMP-9, TIMP-1, and the MMP-9/TIMP-1 ratio were increased in children with NAFLD. Concentrations of AST, ALT, GGT, and leptin were elevated in serum patients with NAFLD, while concentration of other inflammatory or liver injury markers was unchanged. …”
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Booster Vaccination against Yellow Fever in Gambian children-(BoVY) -a Phase 3 clinical trial to establish safety and immunogenicity of repeated YF vaccination in healthy Gambian c... by David Jeffries, Caitlin Pley, Beate Kampmann, Mam Nabou Leigh, Julia Strandmark, Ed Clarke, Peter Ndow, Ebrima Kanteh, Amadou Faal, Elishia Roberts

“…The children will receive booster doses at 15 months, 4 years, or 8.5 years. …”
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Thyroid Function in Chronically Transfused Children with Beta Thalassemia Major: A Cross-Sectional Hospital Based Study by Suraj Haridas Upadya, M. S. Rukmini, Sowmya Sundararajan, B. Shantharam Baliga, Nutan Kamath

“…Methodology. BTM children, 3 years old and above, on regular blood transfusions with serum ferritin > 1500 mcg/l were included in the study. …”
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Seroprevalence of Hepatitis C, Hepatitis B, Cytomegalovirus, and Human Immunodeficiency Viruses in Multitransfused Thalassemic Children in Upper Egypt by Ramadan A. Mahmoud, Abdel-Azeem M. El-Mazary, Ashraf Khodeary

“…Frequent blood transfusions in thalassemia major children expose them to the risk of transfusion-transmitted infections (TTIs). …”
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Neonatal BCG vaccination and child survival in TB-exposed and TB-unexposed children: a prospective cohort study by Peter Aaby, Per Kallestrup, Christine Stabell Benn, Sanne M Thysen, Ane Fisker, Victor Francisco Gomes, Frauke Rudolf, Christian Wejse, Adam Roth

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Vitamin B12, folate, and homocysteine levels in children and adolescents with obesity: a systematic review and meta-analysis by Juan R. Ulloque-Badaracco, Esteban A. Alarcon-Braga, Enrique A. Hernandez-Bustamante, Enrique A. Hernandez-Bustamante, Beatrix M. Von-Koeller-Jones, Miguel Huayta-Cortez, Esduardo Saavedra-Custodio, Percy Herrera-Añazco, Vicente A. Benites-Zapata

“…There were no significant differences between children/adolescents with and without obesity with respect to serum vitamin B12 levels (SMD: −0.24; 95% CI: −0.53 to 0.06; p &gt; 0.05, I2 = 74.93%) and folate levels (SMD: −0.12; 95% CI: −0.29 to 0.06; p &gt; 0.05, I2 = 19.6%). …”
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