Determining the association of hyperoxia while on extracorporeal life support with mortality in neonates following Norwood operation by Beshish Asaad G., Aljiffry Alaa, Xiang Yijin, Evans Sean, Scheel Amy, Harriott Ashley, Patel Shayli, Amedi Alan, Harding Amanda, Davis Joel, Shashidharan Subhadra, Kwiatkowski David M.

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Caracterização das crianças com síndrome de Down concomitante ao hipotireoidismo congênito no estado de Mato Grosso, Região Central do Brasil, 2010–2021 by Camila Moraes Mello, Stela Maris Silvestrin

“…OBJECTIVE: Congenital hypothyroidism is a frequent disease in pediatric endocrinology, with a high prevalence among children with Down syndrome. In Brazil, publications on the coexistence of these two syndromes in children are scarce. …”
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Two Paediatric Patients with Encephalopathy and Concurrent COVID-19 Infection: Two Sides of the Same Coin? by Katerina Vraka, Dipak Ram, Siobhan West, Wei Yen Evelyn Chia, Praveen Kurup, Gayathri Subramanian, Hui Jeen Tan

“…However, the first patient was positive for serum MOG antibodies with normal CSF analysis, and the second had negative MOG antibodies but showed significant CSF lymphocytic pleocytosis. …”
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Intestine-derived fibroblast growth factor 19 alleviates lipopolysaccharide-induced liver injury by regulating bile acid homeostasis and directly improving oxidative stress by Xiaomeng Tang, Jingjing Ning, Yilin Zhao, Shuyun Feng, Lujing Shao, Tiantian Liu, Huijie Miao, Yucai Zhang, Chunxia Wang

“…Compound C (CC), an inhibitor of AMP-activated protein kinase (AMPK) activation, was used to confirm the roles of AMPK activation in FGF19-mediated hepatoprotective effects. Results: Serum FGF19 levels were significantly lower in children with sepsis than in healthy controls (115 pg/mL vs. 79 pg/mL, P=0.03). …”
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Hepatic Iron Quantification on 3 Tesla (3 T) Magnetic Resonance (MR): Technical Challenges and Solutions by Muhammad Anwar, John Wood, Deepa Manwani, Benjamin Taragin, Suzette O. Oyeku, Qi Peng

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Clinical value of miR-200b in diagnosis and prognosis of childhood pneumonia by Weiwei Qi, Beibei Teng, Fan Zhang, Ying Chen, Jinmei Xu, Jinling Luan

“…Results The expression of miR-200b in serum of CP children was upregulated. ROC analysis prompted that upregulation of miR-200b could be effective in distinguishing between CP and healthy children. …”
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Factors associated with low bone mineral density in Turner syndrome: a multicenter prospective observational study by Kento Ikegawa, Eri Koga, Tomoyo Itonaga, Hideya Sakakibara, Masanobu Kawai, Yukihiro Hasegawa

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Increased Incidence of Thyroid Dysfunction and Autoimmunity in Patients with Vernal Keratoconjunctivitis by Stefano Stagi, Neri Pucci, Laura Di Grande, Cinzia de Libero, Roberto Caputo, Stefano Pantano, Ivan Mattei, Francesca Mori, Maurizio de Martino, Elio Novembre

“…Thyroid function and autoimmunity abnormalities are frequently present in children with VKC. Children with VKC should be screened for thyroid function and evaluated for thyroid autoimmunity.…”
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Evaluating the Correlation between High Titers of Tissue-Transglutaminase Antibody with the Grade of Severity of Villous Atrophy in Syrian Patients with Celiac Disease by A. Alhabbal, I. Abou Khamis

“…Two samples were taken from the duodenum and were evaluated by an expert pathologist according to Marsh grading. Serum anti-tTG IgA levels were measured as well to determine any association between the levels of serum anti-tTG IgA and Marsh grading.Results. …”
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Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and gut microbiota composition: what do we know? by Veronica Maria Tagi, Veronica Maria Tagi, Martina Tosi, Martina Tosi, Ilenia Pia Greco, Eliana Stucchi, Elvira Verduci, Elvira Verduci, Gianvincenzo Zuccotti, Gianvincenzo Zuccotti

“…Scant literature is available regarding the microbiota composition in children with PANDAS, however few studies support the hypothesis that streptococcal infections may alter gut microbiota composition in these patients, leading to chronic inflammation that may impact the brain function and behavior. …”
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Assessment of Immunological, Skeletal, and Thyroid Function Abnormalities in Paediatric Morphoea by Vibhu Mendiratta, Anuja Yadav, Amit K. Meena, Suvarna Samudrala, Ritu Singh, Vishal Parmar

“…Anaemia was present in 14.28% patients. Serum IgE levels were raised in 33.33% patients. …”
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Odevixibat treatment in a child with hypoplastic left heart syndrome and severe cholestatic pruritus: a case report by Rainer Ganschow, Christof Maucksch, Peter Rauschkolb, Martin B. E. Schneider

“…The patient's serum bile acids decreased from 111 μmol/L before treatment with odevixibat to 24 μmol/L within 1 month of initiating therapy. …”
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Genetic and environmental contribution to phenotypic resemblance between Iranian couples: Tehran Cardiometabolic and Genetic Study (TCGS) by Parisa Riahi, Amir Hossein Saeidian, Albert Tenesa, Carolyn T. Hogan, Michael March, Kamran Guity, Mahmoud Amiri Roudbar, Asieh Zahedi, Maryam Zarkesh, Farideh Neshati, Mehdi Hedayati, Fereidoun Azizi, Hakon Hakonarson, Maryam S. Daneshpour, Mahdi Akbarzadeh

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Enhancement of CD8+T cell cytotoxicity activity by IFN-α implies alternative pathologic role in systemic lupus erythematosus by Chen-xing Zhang, You-ying Mao, Yu-pin Tan, Mei-yu Zhang, Kang Shao, Shu-jun Wang, Ping Ji, Jia-yuan Wang, Lei Yin, Ying Wang

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Interpretable machine learning-based prediction of 28-day mortality in ICU patients with sepsis: a multicenter retrospective study by Li Shen, Li Shen, Jiaqiang Wu, Jianger Lan, Chao Chen, Yi Wang, Zhiping Li

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Relapsing Campylobacter jejuni Systemic Infections in a Child with X-Linked Agammaglobulinemia by Paola Ariganello, Giulia Angelino, Alessia Scarselli, Irene Salfa, Martina Della Corte, Arianna De Matteis, Patrizia D'Argenio, Susanna Livadiotti, Emma C. Manno, Cristina Russo, Andrea Finocchi, Caterina Cancrini

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Assessment of myocardial deformation by CMR tissue tracking reveals left ventricular subclinical myocardial dysfunction in patients with gynecologic cancer undergoing chemotherapy by Kai Tao, Kai Tao, Lu Ye, Yan-Jia-Ni Xu, Yan-Jia-Ni Xu, Meng-Xi Yang, Ru-Tie Yin, Qing-Li Li, Xiao-Juan Lin, Ke-Min Li, Liang Song, Yu Ma, Lan Zhong, Ying Hu, Hua-Yan Xu, Dan-Qing Wang, Ying-Kun Guo

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Autoantibodies to Zinc Transporter 8 and SLC30A8 Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa by Raouia Fakhfakh, Sana Kmiha, Safa Tahri, Sawsan Feki, Ferjeni Zouidi, Olfa Abida, Mongia Hachicha, Thouraya Kammoun, Hatem Masmoudi

“…As no data on ZnT8-Ab in Tunisian patients has been reported, we aim to evaluate the relationships between ZnT8-Ab, ZnT8 coding gene (SLC30A8) promoter polymorphism, and T1D risk in newly diagnosed children. Methods. ZnT8-Ab were measured in the serum of T1D newly affected children (n=156) who were admitted to the pediatric department of the Hedi Chaker University Hospital of Sfax. …”
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γ-Secretase Inhibitor Alleviates Acute Airway Inflammation of Allergic Asthma in Mice by Downregulating Th17 Cell Differentiation by Weixi Zhang, Xueya Zhang, Anqun Sheng, Cuiye Weng, Tingting Zhu, Wei Zhao, Changchong Li

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Common Variable Immunodeficiency Associated with Hepatosplenic T-Cell Lymphoma Mimicking Juvenile Systemic Lupus Erythematosus by A. A. Jesus, C. M. A. Jacob, C. A. Silva, M. Dorna, A. C. Pastorino, M. Carneiro-Sampaio

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